Details for: FUT8
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 352.3734
Cell Significance Index: -54.8100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 214.0012
Cell Significance Index: -54.2800 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 125.4528
Cell Significance Index: -51.6800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 119.0157
Cell Significance Index: -56.1900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 114.0411
Cell Significance Index: -46.3300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 84.0509
Cell Significance Index: -56.4000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 48.4947
Cell Significance Index: -46.3000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 45.0300
Cell Significance Index: -55.5200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.6095
Cell Significance Index: -55.2100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 14.7035
Cell Significance Index: -32.1800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.1420
Cell Significance Index: -55.8100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 13.9185
Cell Significance Index: -42.7500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 6.4362
Cell Significance Index: 137.5800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.9749
Cell Significance Index: 65.1400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 2.7035
Cell Significance Index: 46.3300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.5113
Cell Significance Index: 503.7700 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 2.3265
Cell Significance Index: 23.4700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.1624
Cell Significance Index: 775.6000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.9994
Cell Significance Index: 47.9500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.9898
Cell Significance Index: 122.3000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.9842
Cell Significance Index: 322.7200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.8110
Cell Significance Index: 1252.5800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.6920
Cell Significance Index: 74.8400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.6419
Cell Significance Index: 62.1800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.3348
Cell Significance Index: 89.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1660
Cell Significance Index: 126.8200 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.1252
Cell Significance Index: 21.9600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1099
Cell Significance Index: 62.2800 - Cell Name: peg cell (CL4033014)
Fold Change: 1.0656
Cell Significance Index: 24.6200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.9820
Cell Significance Index: 58.9600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.8946
Cell Significance Index: 25.5300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7836
Cell Significance Index: 21.9000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5858
Cell Significance Index: 57.9500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5353
Cell Significance Index: 106.2300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4125
Cell Significance Index: 11.8900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2758
Cell Significance Index: 52.4900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2623
Cell Significance Index: 493.8100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2451
Cell Significance Index: 221.3100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.2153
Cell Significance Index: 2.6700 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.2141
Cell Significance Index: 3.0800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1928
Cell Significance Index: 122.4600 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 0.1924
Cell Significance Index: 2.6900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.1823
Cell Significance Index: 4.6900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1808
Cell Significance Index: 98.7400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1407
Cell Significance Index: 63.8500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1267
Cell Significance Index: 22.8400 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 0.1189
Cell Significance Index: 1.1900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0815
Cell Significance Index: 5.6400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0577
Cell Significance Index: 88.8000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0379
Cell Significance Index: 69.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0066
Cell Significance Index: 0.8100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0026
Cell Significance Index: 3.4700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0022
Cell Significance Index: 0.0600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0003
Cell Significance Index: 0.0200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0006
Cell Significance Index: -0.2600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0057
Cell Significance Index: -0.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0210
Cell Significance Index: -0.9500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0281
Cell Significance Index: -4.0800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0580
Cell Significance Index: -9.9000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0615
Cell Significance Index: -45.5400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0663
Cell Significance Index: -48.6400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0714
Cell Significance Index: -54.0200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0909
Cell Significance Index: -11.6500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0990
Cell Significance Index: -55.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1002
Cell Significance Index: -62.5800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1662
Cell Significance Index: -47.8300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1876
Cell Significance Index: -22.1200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2360
Cell Significance Index: -6.9300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2996
Cell Significance Index: -63.1100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3161
Cell Significance Index: -6.2500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3531
Cell Significance Index: -41.1500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3571
Cell Significance Index: -16.6500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3604
Cell Significance Index: -36.8100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3859
Cell Significance Index: -49.8600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4227
Cell Significance Index: -22.0200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.4264
Cell Significance Index: -9.0500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4323
Cell Significance Index: -45.0100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4777
Cell Significance Index: -24.8200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4818
Cell Significance Index: -35.9100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4893
Cell Significance Index: -56.0600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5567
Cell Significance Index: -17.8300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5646
Cell Significance Index: -36.4300 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.5698
Cell Significance Index: -7.3900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.6010
Cell Significance Index: -21.1200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.6211
Cell Significance Index: -29.1900 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: -0.6249
Cell Significance Index: -6.7000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.6402
Cell Significance Index: -45.2800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6428
Cell Significance Index: -50.9100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6505
Cell Significance Index: -39.8800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7553
Cell Significance Index: -24.7300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.7555
Cell Significance Index: -10.8200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7786
Cell Significance Index: -49.0700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7850
Cell Significance Index: -25.0000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7864
Cell Significance Index: -41.2900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.8258
Cell Significance Index: -17.8900 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.8830
Cell Significance Index: -12.6800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9073
Cell Significance Index: -18.2200 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.9450
Cell Significance Index: -16.3400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.9607
Cell Significance Index: -11.9800 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -1.0885
Cell Significance Index: -14.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1371197739
Symbol: FUT8_HUMAN
Name: Alpha-(1,6)-fucosyltransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9133635
Title: Purification and cDNA cloning of GDP-L-Fuc:N-acetyl-beta-D-glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT) from human gastric cancer MKN45 cells.
PubMed ID: 9133635
PubMed ID: 10814706
Title: Genomic structure and promoter analysis of the human alpha1,6-fucosyltransferase gene (FUT8).
PubMed ID: 10814706
PubMed ID: 14514715
Title: Activity and tissue distribution of splice variants of alpha6-fucosyltransferase in human embryogenesis.
PubMed ID: 14514715
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10764839
Title: A sequence motif involved in the donor substrate binding by alpha1,6-fucosyltransferase: the role of the conserved arginine residues.
PubMed ID: 10764839
PubMed ID: 25171405
Title: A secreted tyrosine kinase acts in the extracellular environment.
PubMed ID: 25171405
PubMed ID: 29304374
Title: Biallelic Mutations in FUT8 Cause a Congenital Disorder of Glycosylation with Defective Fucosylation.
PubMed ID: 29304374
PubMed ID: 17172260
Title: Crystal structure of mammalian alpha1,6-fucosyltransferase, FUT8.
PubMed ID: 17172260
PubMed ID: 30237576
Title: Autozygome and high throughput confirmation of disease genes candidacy.
PubMed ID: 30237576
Sequence Information:
- Length: 575
- Mass: 66516
- Checksum: 5AE24A93881E18D0
- Sequence:
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGK DHEILRRRIE NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWDGYS KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK
Genular Protein ID: 443855701
Symbol: A8K8P8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 575
- Mass: 66516
- Checksum: C52E5E78CCA05730
- Sequence:
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGE DHEILRRRIE NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWNGYS KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.