Details for: HELLS

Gene ID: 3070

Symbol: HELLS

Ensembl ID: ENSG00000119969

Description: helicase, lymphoid specific

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 2.1
    Marker Score: 3023
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.86
    Marker Score: 1607
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.65
    Marker Score: 1552
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.56
    Marker Score: 1954
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.52
    Marker Score: 1833
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.49
    Marker Score: 4060
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168513
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.45
    Marker Score: 1545
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.35
    Marker Score: 759
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.35
    Marker Score: 2297
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.31
    Marker Score: 377
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.28
    Marker Score: 3786.5
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.22
    Marker Score: 1233
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.16
    Marker Score: 2429.5
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.14
    Marker Score: 4420
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.09
    Marker Score: 1235
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 1.07
    Marker Score: 806
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.04
    Marker Score: 4270
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 1.03
    Marker Score: 645
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.02
    Marker Score: 816
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.02
    Marker Score: 13441
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71743
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47967
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30400
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.97
    Marker Score: 708
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.97
    Marker Score: 3802.5
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2403
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 484
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 439
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5274
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.92
    Marker Score: 3393
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.91
    Marker Score: 5475
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2716
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.89
    Marker Score: 1186
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.89
    Marker Score: 1438
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5295
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 310.5
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.86
    Marker Score: 7358.5
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.82
    Marker Score: 407
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.81
    Marker Score: 626
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.81
    Marker Score: 49958
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.8
    Marker Score: 2006
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.79
    Marker Score: 3276
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.77
    Marker Score: 482
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 0.76
    Marker Score: 626
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.76
    Marker Score: 2070
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.76
    Marker Score: 417
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.76
    Marker Score: 303
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 575
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.75
    Marker Score: 1768
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 378
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.71
    Marker Score: 176
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.71
    Marker Score: 6655
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 0.69
    Marker Score: 971
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.68
    Marker Score: 10682
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.68
    Marker Score: 25115.5
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.68
    Marker Score: 621
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.68
    Marker Score: 249
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.67
    Marker Score: 2830
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.66
    Marker Score: 4930
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.66
    Marker Score: 323
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.66
    Marker Score: 1566
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.66
    Marker Score: 154
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.65
    Marker Score: 267.5
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.64
    Marker Score: 682
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.64
    Marker Score: 6070
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.64
    Marker Score: 586
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.63
    Marker Score: 696
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.62
    Marker Score: 357
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.62
    Marker Score: 1484
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.62
    Marker Score: 372
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.62
    Marker Score: 1013.5
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.62
    Marker Score: 23434
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.61
    Marker Score: 296
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.61
    Marker Score: 21222
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.61
    Marker Score: 278
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.6
    Marker Score: 2500
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.6
    Marker Score: 300
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.6
    Marker Score: 566
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.6
    Marker Score: 626
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.6
    Marker Score: 158
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.59
    Marker Score: 2284
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.59
    Marker Score: 222
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.59
    Marker Score: 247
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.58
    Marker Score: 161
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.58
    Marker Score: 2359
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.58
    Marker Score: 161
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.57
    Marker Score: 305
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.57
    Marker Score: 381
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.56
    Marker Score: 110
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.56
    Marker Score: 398
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.55
    Marker Score: 9841
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 435
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.54
    Marker Score: 459
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.54
    Marker Score: 512
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.54
    Marker Score: 578.5
  • Cell Name: pre-conventional dendritic cell (CL0002010)
    Fold Change: 0.53
    Marker Score: 158
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.53
    Marker Score: 683
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.52
    Marker Score: 4016

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Other Information

**Key characteristics:** - The protein is a helicase, which is an enzyme that breaks DNA strands. - It is a lymphoid-specific protein, which means that it is only expressed in cells of the immune system. - It is involved in the apoptotic process, as it is expressed in cells that are about to die. - It is also involved in the regulation of cell cycle progression, as it is expressed in cells that are dividing. **Pathways and functions:** - The HELLS protein is involved in the apoptotic process by breaking DNA strands and releasing fragments that can trigger the activation of caspases, which are enzymes that break down the body's proteins. - It is also involved in the regulation of cell cycle progression by promoting the transition from G1 to S phase. - It is involved in the negative regulation of gene expression via cpg island methylation, as it can bind to DNA methyl groups and prevent them from binding to transcription factors, which can then activate gene expression. - It is also involved in the negative regulation of intrinsic apoptotic signaling pathway, as it can bind to DNA and prevent it from binding to transcription factors that can activate apoptosis. **Clinical significance:** - Mutations in the HELLS gene have been linked to several human cancers, including leukemia and lymphoma. - Targeting the HELLS gene has been investigated as a potential treatment for cancer, as it could be used to inhibit cancer cell growth. - However, further research is needed to develop effective therapeutic strategies that target the HELLS gene in a safe and effective manner.

Genular Protein ID: 1361080485

Symbol: HELLS_HUMAN

Name: Lymphoid-specific helicase

UniProtKB Accession Codes:

Q9NRZ9 B2RB41 Q3LID1 Q6I7N7 Q76H76 Q76H77 Q76H78 Q76H79 Q76H80 Q76H81 Q7Z397 Q7Z5X2 Q8N6P4 Q9H4P5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChEBI 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 26 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 20 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 9 Pumba 1 RNAct 1 RefSeq 10 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10910076

Title: Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia.

PubMed ID: 10910076

PubMed ID: 15305370

Title: Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer.

PubMed ID: 15305370

DOI: 10.1002/ijc.20407

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12880961

Title: Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma.

PubMed ID: 12880961

DOI: 10.1016/s0304-3835(03)00085-5

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26216346

Title: Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

PubMed ID: 26216346

DOI: 10.1038/ncomms8870

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

Sequence Information:

  • Length: 838
  • Mass: 97074
  • Checksum: FE8C644C23F2526E
  • Sequence:
    • MPAERPAGSG GSEAPAMVEQ LDTAVITPAM LEEEEQLEAA GLERERKMLE KARMSWDRES 
TEIRYRRLQH LLEKSNIYSK FLLTKMEQQQ LEEQKKKEKL ERKKESLKVK KGKNSIDASE 
EKPVMRKKRG REDESYNISE VMSKEEILSV AKKNKKENED ENSSSTNLCV EDLQKNKDSN 
SIIKDRLSET VRQNTKFFFD PVRKCNGQPV PFQQPKHFTG GVMRWYQVEG MEWLRMLWEN 
GINGILADEM GLGKTVQCIA TIALMIQRGV PGPFLVCGPL STLPNWMAEF KRFTPDIPTM 
LYHGTQEERQ KLVRNIYKRK GTLQIHPVVI TSFEIAMRDR NALQHCYWKY LIVDEGHRIK 
NMKCRLIREL KRFNADNKLL LTGTPLQNNL SELWSLLNFL LPDVFDDLKS FESWFDITSL 
SETAEDIIAK EREQNVLHML HQILTPFLLR RLKSDVALEV PPKREVVVYA PLSKKQEIFY 
TAIVNRTIAN MFGSSEKETI ELSPTGRPKR RTRKSINYSK IDDFPNELEK LISQIQPEVD 
RERAVVEVNI PVESEVNLKL QNIMMLLRKC CNHPYLIEYP IDPVTQEFKI DEELVTNSGK 
FLILDRMLPE LKKRGHKVLL FSQMTSMLDI LMDYCHLRDF NFSRLDGSMS YSEREKNMHS 
FNTDPEVFIF LVSTRAGGLG INLTAADTVI IYDSDWNPQS DLQAQDRCHR IGQTKPVVVY 
RLVTANTIDQ KIVERAAAKR KLEKLIIHKN HFKGGQSGLN LSKNFLDPKE LMELLKSRDY 
EREIKGSREK VISDKDLELL LDRSDLIDQM NASGPIKEKM GIFKILENSE DSSPECLF

Genular Protein ID: 3784979962

Symbol: Q76H82_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q76H82

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GO 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

Sequence Information:

  • Length: 97
  • Mass: 11210
  • Checksum: 0DB80077AA17A3FE
  • Sequence:
    • MPAERPAGSG GSEAPAMVEQ LDTAVITPAM LEEEEQLEAA GLERERKMLE KARMSWDRES 
TEIRYRRLQH LLEKSNIYSK FLLTKMEQQQ LETVMKI

Genular Protein ID: 3860705216

Symbol: A0A087WSW7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WSW7

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 700
  • Mass: 81036
  • Checksum: AEE7C610A32B3161
  • Sequence:
    • MQVKRSQEIL SVAKKNKKEN EDENSSSTNL CVEDLQKNKD SNSIIKDRLS ETVRQNTKFF 
FDPVRKCNGQ PVPFQQPKHF TGGVMRWYQV EGMEWLRMLW ENGINGILAD EMGLGKTVQC 
IATIALMIQR GVPGPFLVCG PLSTLPNWMA EFKRFTPDIP TMLYHGTQEE RQKLVRNIYK 
RKGTLQIHPV VITSFEIAMR DRNALQHCYW KYLIVDEGHR IKNMKCRLIR ELKRFNADNK 
LLLTGTPLQN NLSELWSLLN FLLPDVFDDL KSFESWFDIT SLSETAEDII AKEREQNVLH 
MLHQILTPFL LRRLKSDVAL EVPPKREVVV YAPLSKKQEI FYTAIVNRTI ANMFGSSEKE 
TIELSPTGRP KRRTRKSINY SKIDDFPNEL EKLISQIQPE VDRERAVVEV NIPVESEVNL 
KLQNIMMLLR KCCNHPYLIE YPIDPVTQEF KIDEELVTNS GKFLILDRML PELKKRGHKV 
LLFSQMTSML DILMDYCHLR DFNFSRLDGS MSYSEREKNM HSFNTDPEVF IFLVSTRAGG 
LGINLTAADT VIIYDSDWNP QSDLQAQDRC HRIGQTKPVV VYRLVTANTI DQKIVERAAA 
KRKLEKLIIH KNHFKGGQSG LNLSKNFLDP KELMELLKSR DYEREIKGSR EKVISDKDLE 
LLLDRSDLID QMNASGPIKE KMGIFKILEN SEDSSPECLF

Genular Protein ID: 1494177214

Symbol: Q0VGL2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q0VGL2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GenomeRNAi 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 8 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 97
  • Mass: 11292
  • Checksum: 8CD805C6488F87FB
  • Sequence:
    • MPAERPAGSG GSEAPAMVEQ LDTAVITPAM LEEEEQLEAA GLERERKMLE KARMSWDRES 
TEIRYRRLQH LLEKSNIYSK FLLTKMEQQK KKKKKKK

Genular Protein ID: 3374547472

Symbol: A0A0B4J1V9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0B4J1V9

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 4 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 884
  • Mass: 102715
  • Checksum: 35FE7D7294C66283
  • Sequence:
    • MPAERPAGSG GSEAPAMVEQ LDTAVITPAM LEEEEQLEAA GLERERKMLE KARMSWDRES 
TEIRYRRLQH LLEKSNIYSK FLLTKMEQQQ LEEQKKKEKL ERKKESLKVK KGKNSIDASE 
EKPVMRKKRG REDESYNISE VMSKEEILSV AKKNKKENED ENSSSTNLCV EDLQKNKDSN 
SIIKDRLSET VRQNTKFFFD PVRKCNGQPV PFQQPKHFTG GVMRWYQVEG MEWLRMLWEN 
GINGILADEM GLGKTVQCIA TIALMIQRGV PGPFLVCGPL STLPNWMAEF KRFTPDIPTM 
LYHGTQEERQ KLVRNIYKRK GTLQIHPVVI TSFEIAMRDR NALQHCYWKY LIVDEGHRIK 
NMKCRLIREL KRFNADNKLL LTGTPLQNNL SELWSLLNFL LPDVFDDLKS FESWFDITSL 
SETAEDIIAK EREQNVLHML HQERIPRMYV SEFTDEGFFE GKLPSRKDLY DIRPYENTYL 
LKLHTNFEIL TPFLLRRLKS DVALEVPPKR EVVVYAPLSK KQEIFYTAIV NRTIANMFGS 
SEKETIELSP TGRPKRRTRK SINYSKIDDF PNELEKLISQ IQPEVDRERA VVEVNIPVES 
EVNLKLQNIM MLLRKCCNHP YLIEYPIDPV TQEFKIDEEL VTNSGKFLIL DRMLPELKKR 
GHKVLLFSQM TSMLDILMDY CHLRDFNFSR LDGSMSYSER EKNMHSFNTD PEVFIFLVST 
RAGGLGINLT AADTVIIYDS DWNPQSDLQA QDRCHRIGQT KPVVVYRLVT ANTIDQKIVE 
RAAAKRKLEK LIIHKNHFKG GQSGLNLSKN FLDPKELMEL LKSRDYEREI KGSREKVISD 
KDLELLLDRS DLIDQMNASG PIKEKMGIFK ILENSEDSSP ECLF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.