Details for: NRG1

Gene ID: 3084

Symbol: NRG1

Ensembl ID: ENSG00000157168

Description: neuregulin 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: granule cell (CL0000120)
    Fold Change: 11.48
    Marker Score: 86,552
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 10.72
    Marker Score: 56,216
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 10.56
    Marker Score: 7,949
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 10.12
    Marker Score: 54,376
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 9.73
    Marker Score: 13,688
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 9.31
    Marker Score: 21,407
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 8.46
    Marker Score: 28,365
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 8.31
    Marker Score: 280,711
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 4.43
    Marker Score: 2,128
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 4.23
    Marker Score: 2,458
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.7
    Marker Score: 8,129
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 3.51
    Marker Score: 1,158
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 3.33
    Marker Score: 4,147
  • Cell Name: bipolar neuron (CL0000103)
    Fold Change: 3.3
    Marker Score: 1,108
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.97
    Marker Score: 1,141
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 2.93
    Marker Score: 890
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.67
    Marker Score: 39,975
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.58
    Marker Score: 1,079
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.39
    Marker Score: 758
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.35
    Marker Score: 1,315
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.29
    Marker Score: 3,846
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.27
    Marker Score: 2,014
  • Cell Name: interneuron (CL0000099)
    Fold Change: 2.18
    Marker Score: 995
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.06
    Marker Score: 21,300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.05
    Marker Score: 125,845
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.97
    Marker Score: 1,145
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.92
    Marker Score: 18,290
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.87
    Marker Score: 7,628
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.86
    Marker Score: 509
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.85
    Marker Score: 5,281
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.82
    Marker Score: 3,709
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.79
    Marker Score: 1,014
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.74
    Marker Score: 14,941
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.65
    Marker Score: 2,552
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6
    Marker Score: 1,162
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.6
    Marker Score: 60,663
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.59
    Marker Score: 12,225
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.59
    Marker Score: 954
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.54
    Marker Score: 3,619
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.51
    Marker Score: 4,935
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.5
    Marker Score: 6,954
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.48
    Marker Score: 1,356
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,533
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.39
    Marker Score: 686
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 864
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 1.36
    Marker Score: 399
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.35
    Marker Score: 12,664
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.29
    Marker Score: 1,467
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.27
    Marker Score: 6,258
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.22
    Marker Score: 19,086
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.2
    Marker Score: 2,181
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.2
    Marker Score: 434
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.17
    Marker Score: 1,258
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.1
    Marker Score: 345
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.09
    Marker Score: 499
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.08
    Marker Score: 316
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 1.05
    Marker Score: 1,010
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.05
    Marker Score: 1,302
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.05
    Marker Score: 435
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.04
    Marker Score: 20,748
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.04
    Marker Score: 705
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251,766
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 791
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.03
    Marker Score: 6,636
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.03
    Marker Score: 2,519
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.02
    Marker Score: 880
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.01
    Marker Score: 379
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1
    Marker Score: 337
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1
    Marker Score: 4,324
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,790
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,013
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1
    Marker Score: 1,101
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.99
    Marker Score: 314
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.99
    Marker Score: 5,954
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.98
    Marker Score: 3,806
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,405
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 505
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 459
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.96
    Marker Score: 53,876
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,411
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.94
    Marker Score: 1,003
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.93
    Marker Score: 378
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 371
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,736
  • Cell Name: visceromotor neuron (CL0005025)
    Fold Change: 0.91
    Marker Score: 266
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.91
    Marker Score: 3,237
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.89
    Marker Score: 609
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.89
    Marker Score: 425
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.88
    Marker Score: 453
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,279
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.86
    Marker Score: 995
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.86
    Marker Score: 2,055
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.85
    Marker Score: 3,567
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.84
    Marker Score: 265
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 0.81
    Marker Score: 229
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.8
    Marker Score: 4,321
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.8
    Marker Score: 527
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.8
    Marker Score: 17,012

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NRG1 is a type of growth factor that belongs to the epidermal growth factor (EGF) family. It is a membrane-bound protein that interacts with the ErbB4 receptor tyrosine kinase, which is a member of the ErbB family of receptors. NRG1 is produced in various tissues, including the nervous system, and is involved in the regulation of cell growth, differentiation, and survival. **Pathways and Functions** NRG1 signaling pathways are complex and involve multiple steps. The primary pathway involves the binding of NRG1 to the ErbB4 receptor, which activates a cascade of downstream signaling events. These events include: 1. Activation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway, which promotes cell survival and proliferation. 2. Activation of the mitogen-activated protein kinase (MAPK) pathway, which regulates cell growth and differentiation. 3. Regulation of the NMDA receptor, which is involved in synaptic plasticity and learning. 4. Modulation of the ErbB2/3/4 signaling pathway, which regulates cell growth, differentiation, and survival. NRG1 has been implicated in various physiological and pathological processes, including: 1. Nervous system development and maturation 2. Cardiac muscle cell differentiation and development 3. Mammary gland development and cancer 4. Neurodegenerative diseases, such as Alzheimer's and Parkinson's 5. Wound healing and tissue repair **Clinical Significance** Dysregulation of NRG1 signaling has been implicated in various diseases, including: 1. Autism spectrum disorder (ASD) 2. Schizophrenia 3. Bipolar disorder 4. Cancer, including breast and lung cancer 5. Neurodegenerative diseases, such as Alzheimer's and Parkinson's Abnormal NRG1 expression has been observed in various tissues, including the brain, heart, and mammary gland. This suggests that NRG1 may play a critical role in the development and maintenance of these tissues. In addition, NRG1 has been used as a therapeutic target for various diseases, including cancer and neurodegenerative diseases. Small molecule inhibitors of NRG1 signaling have been developed, which have shown promise in preclinical models. In conclusion, NRG1 is a critical regulator of cell growth, differentiation, and survival in the nervous system and other tissues. Its dysregulation has been implicated in various diseases, and it has been identified as a potential therapeutic target for the treatment of these diseases. **References** 1. Yamaguchi et al. (1994). Neuregulin, a member of the EGF family, is a ligand for ErbB4 receptor tyrosine kinase. Journal of Biological Chemistry, 269(19), 12747-12754. 2. Lee et al. (1995). Neuregulin, a ligand for the ErbB4 receptor, promotes cell growth and differentiation in the nervous system. Journal of Neuroscience, 15(11), 6978-6988. 3. Zhang et al. (2001). Neuregulin 1 promotes cardiac muscle cell differentiation and development. Journal of Cardiovascular and Brain Disorders, 1(1), 1-9. 4. Wang et al. (2017). Neuregulin 1 signaling in cancer: a review. Journal of Cancer Research and Clinical Oncology, 143(10), 2017-2028.

Genular Protein ID: 2246918759

Symbol: NRG1_HUMAN

Name: Pro-neuregulin-1, membrane-bound isoform

UniProtKB Accession Codes:

Q02297 A5YAK4 A5YAK5 A8K1L2 B7Z4Z3 E9PHH4 O14667 P98202 Q02298 Q02299 Q07110 Q07111 Q12779 Q12780 Q12781 Q12782 Q12783 Q12784 Q15491 Q7RTV9 Q7RTW0 Q7RTW1 Q7RTW2 Q8NFN1 Q8NFN2 Q8NFN3 Q9UPE3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 9 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 40 EMDB 3 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 55 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 9 PIR 9 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 11 RNAct 1 Reactome 20 RefSeq 15 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1350381

Title: Identification of heregulin, a specific activator of p185erbB2.

PubMed ID: 1350381

DOI: 10.1126/science.256.5060.1205

PubMed ID: 7509448

Title: Structural and functional aspects of the multiplicity of Neu differentiation factors.

PubMed ID: 7509448

DOI: 10.1128/mcb.14.3.1909-1919.1994

PubMed ID: 8096067

Title: Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system.

PubMed ID: 8096067

DOI: 10.1038/362312a0

PubMed ID: 7782315

Title: Sensory and motor neuron-derived factor. A novel heregulin variant highly expressed in sensory and motor neurons.

PubMed ID: 7782315

DOI: 10.1074/jbc.270.24.14523

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 9333014

Title: Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175.

PubMed ID: 9333014

DOI: 10.1038/sj.onc.1201317

PubMed ID: 12145742

Title: Neuregulin 1 and susceptibility to Schizophrenia.

PubMed ID: 12145742

DOI: 10.1086/342734

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.m702953200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7689552

Title: Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor.

PubMed ID: 7689552

DOI: 10.1016/s0021-9258(17)46636-1

PubMed ID: 1348215

Title: Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells.

PubMed ID: 1348215

DOI: 10.1016/0092-8674(92)90131-u

PubMed ID: 7902537

Title: Heregulin induces tyrosine phosphorylation of HER4/p180erbB4.

PubMed ID: 7902537

DOI: 10.1038/366473a0

PubMed ID: 10523851

Title: Gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line.

PubMed ID: 10523851

DOI: 10.1038/sj.onc.1202950

PubMed ID: 10597312

Title: Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation.

PubMed ID: 10597312

DOI: 10.1038/sj.onc.1203136

PubMed ID: 10867024

Title: Ligand discrimination in signaling through an ErbB4 receptor homodimer.

PubMed ID: 10867024

DOI: 10.1074/jbc.c901015199

PubMed ID: 20682778

Title: Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling.

PubMed ID: 20682778

DOI: 10.1074/jbc.m110.113878

PubMed ID: 8062828

Title: Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.

PubMed ID: 8062828

DOI: 10.1002/j.1460-2075.1994.tb06658.x

PubMed ID: 8639490

Title: High-resolution solution structure of the EGF-like domain of heregulin-alpha.

PubMed ID: 8639490

DOI: 10.1021/bi952626l

Sequence Information:

  • Length: 640
  • Mass: 70392
  • Checksum: C30D3F614AADFF62
  • Sequence:
    • MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS 
SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 
DSASANITIV ESNEIITGMP ASTEGAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLV 
KCAEKEKTFC VNGGECFMVK DLSNPSRYLC KCQPGFTGAR CTENVPMKVQ NQEKAEELYQ 
KRVLTITGIC IALLVVGIMC VVAYCKTKKQ RKKLHDRLRQ SLRSERNNMM NIANGPHHPN 
PPPENVQLVN QYVSKNVISS EHIVEREAET SFSTSHYTST AHHSTTVTQT PSHSWSNGHT 
ESILSESHSV IVMSSVENSR HSSPTGGPRG RLNGTGGPRE CNSFLRHARE TPDSYRDSPH 
SERYVSAMTT PARMSPVDFH TPSSPKSPPS EMSPPVSSMT VSMPSMAVSP FMEEERPLLL 
VTPPRLREKK FDHHPQQFSS FHHNPAHDSN SLPASPLRIV EDEEYETTQE YEPAQEPVKK 
LANSRRAKRT KPNGHIANRL EVDSNTSSQS SNSESETEDE RVGEDTPFLG IQNPLAASLE 
ATPAFRLADS RTNPAGRFST QEEIQARLSS VIANQDPIAV

Genular Protein ID: 1124773042

Symbol: A6MW55_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6MW55

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 3 SUPFAM 2

Citations:

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.M702953200

Sequence Information:

  • Length: 498
  • Mass: 55035
  • Checksum: 90574C187B0C5E7C
  • Sequence:
    • MGKGRAGRVG TTALPPQLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKD 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNEIITGMPA 
STEGAYVSSE SPIRISVSTE GANTSSSTST STTGTSHLVK CAEKEKTFCV NGGECFMVKD 
LSNPSRYLCK CPNEFTGDRC QNYVMASFYK HLGIEFMEAE ELYQKRVLTI TGICIALLVV 
GIMCVVAYCK TKKQRKKLHD RLRQSLRSER NNMMNIANGP HHPNPPPENV QLVNQYASKN 
VISSEHIVER EAETPFSTSH YTSTAHHSTT VTQTPSHSWS NEHTESILSE SHSVIVMSSV 
ENSRHSSPTG GPRGRLNGTG GPRECNSFLR HARETPDSYR DSPHSERYVS AMTTPARMSP 
VDFHTPSSPK SPPSEMSPPV SSMTVSMPSM AVSPFMEEER PLLLVTPPRL REKKFDHHPQ 
QFSSFHHNPA HDSNSLPA

Genular Protein ID: 4023913363

Symbol: A5YAK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YAK6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 7 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.M702953200

Sequence Information:

  • Length: 214
  • Mass: 23059
  • Checksum: 2FE14468A5E76AB0
  • Sequence:
    • MGKGRAGRVG TTALPPQLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNEIITGMPA 
STEGAYVSSA TSTSTTGASH LVKCAEKEKT FCVNGGECFM VKDLSNPSRY LCKGGGAVPE 
ESADHNRHLH RPPCGRHHVF GGLLQNQETA EKAA

Genular Protein ID: 505547974

Symbol: A0A494C0Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C0Q4

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 700
  • Mass: 76700
  • Checksum: BBC65054BC493626
  • Sequence:
    • MEIYSPDMSE VAAERSSSPS TQLSADPSLD GLPAAEDMPE PQTEDGRTPG LVGLAVPCCA 
CLEAERLRGC LNSEKICIVP ILACLVSLCL CIAGLKWVFV DKIFEYDSPT HLDPGGLGQD 
PIISLDATAA SAVWVSSEAY TSPVSRAQSE SEVQVTVQGD KAVVSFEPSA APTPKNRIFA 
FSFLPSTAPS FPSPTRNPEV RTPKSATQPQ TTETNLQTAP KLSTSTSTTG TSHLVKCAEK 
EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI EFMEAEELYQ 
KRVLTITGIC IALLVVGIMC VVAYCKTKKQ RKKLHDRLRQ SLRSERNNMM NIANGPHHPN 
PPPENVQLVN QYVSKNVISS EHIVEREAET SFSTSHYTST AHHSTTVTQT PSHSWSNGHT 
ESILSESHSV IVMSSVENSR HSSPTGGPRG RLNGTGGPRE CNSFLRHARE TPDSYRDSPH 
SERYVSAMTT PARMSPVDFH TPSSPKSPPS EMSPPVSSMT VSMPSMAVSP FMEEERPLLL 
VTPPRLREKK FDHHPQQFSS FHHNPAHDSN SLPASPLRIV EDEEYETTQE YEPAQEPVKK 
LANSRRAKRT KPNGHIANRL EVDSNTSSQS SNSESETEDE RVGEDTPFLG IQNPLAASLE 
ATPAFRLADS RTNPAGRFST QEEIQARLSS VIANQDPIAV

Genular Protein ID: 709540922

Symbol: A0A494C1F5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C1F5

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 624
  • Mass: 68888
  • Checksum: 0AA7C095D1B3BC39
  • Sequence:
    • MGKGRAGRVG TTALPPRLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNEIITGMPA 
STEGAYVSSE SPIRISVSTE GANTSSSTST STTGTSHLVK CAEKEKTFCV NGGECFMVKD 
LSNPSRYLCK CPNEFTGDRC QNYVMASFYK HLGIEFMEAE ELYQKRVLTI TGICIALLVV 
GIMCVVAYCK TKKQRKKLHD RLRQSLRSER NNMMNIANGP HHPNPPPENV QLVNQYVSKN 
VISSEHIVER EAETSFSTSH YTSTAHHSTT VTQTPSHSWS NGHTESILSE SHSVIVMSSV 
ENSRHSSPTG GPRGRLNGTG GPRECNSFLR HARETPDSYR DSPHSERYVS AMTTPARMSP 
VDFHTPSSPK SPPSEMSPPV SSMTVSMPSM AVSPFMEEER PLLLVTPPRL REKKFDHHPQ 
QFSSFHHNPA HDSNSLPASP LRIVEDEEYE TTQEYEPAQE PVKKLANSRR AKRTKPNGHI 
ANRLEVDSNT SSQSSNSESE TEDERVGEDT PFLGIQNPLA ASLEATPAFR LADSRTNPAG 
RFSTQEEIQA RLSSVIANQD PIAV

Genular Protein ID: 4073230764

Symbol: A6MW54_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6MW54

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 3 SUPFAM 2

Citations:

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.M702953200

Sequence Information:

  • Length: 454
  • Mass: 50514
  • Checksum: 129727D7A36393FF
  • Sequence:
    • MGKGRAGRVG TTALPPRLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVIGKLGND SASANITIVE SNATSTSTTG 
TSHLVKCAEK EKAFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI 
EFMEAEELYQ KRVLTITGIC IALLVVGIMC VVAYCKTKKQ RKKLHDRLRQ SLRSERNNMM 
NIANGPHHPN PPPENVQLVN QYVSKNVISS EHIVEREAET SFSTSHYTST AHHSTTVTQT 
PSHSWSNGHT ESILSESHSV IVMSSVENSR HSSPTGGPRG RLNGTGGPRE CNSFLRHARE 
TPDSYRDSPH SERYVSAMTT PARMSPVDFH TPSSPKSPPS EMSPPVSSMT VSMPSMAVSP 
FMEEERPLLL VTPPRPREKK FDHHPQQFSS FHHN

Genular Protein ID: 966289420

Symbol: B0FYA8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FYA8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 176
  • Mass: 19196
  • Checksum: 4EEB2167FA7B0CB0
  • Sequence:
    • SERKEGRGKG KGKKKERGSG KKPESAAGSQ SPALPPRLKE MKSQESAAGS KLVLRCETSS 
EYSSLRFKWF KNGNELNRKN KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND 
SASANITIVE SNATSTSTTG TSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCK

Genular Protein ID: 404621202

Symbol: A0A494C1F8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C1F8

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 607
  • Mass: 67155
  • Checksum: 26201498D4F08462
  • Sequence:
    • MGKGRAGRVG TTALPPRLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNEIITGMPA 
STEGAYVSSA TSTSTTGTSH LVKCAEKEKT FCVNGGECFM VKDLSNPSRY LCKCPNEFTG 
DRCQNYVMAS FYKHLGIEFM EAEELYQKRV LTITGICIAL LVVGIMCVVA YCKTKKQRKK 
LHDRLRQSLR SERNNMMNIA NGPHHPNPPP ENVQLVNQYV SKNVISSEHI VEREAETSFS 
TSHYTSTAHH STTVTQTPSH SWSNGHTESI LSESHSVIVM SSVENSRHSS PTGGPRGRLN 
GTGGPRECNS FLRHARETPD SYRDSPHSER YVSAMTTPAR MSPVDFHTPS SPKSPPSEMS 
PPVSSMTVSM PSMAVSPFME EERPLLLVTP PRLREKKFDH HPQQFSSFHH NPAHDSNSLP 
ASPLRIVEDE EYETTQEYEP AQEPVKKLAN SRRAKRTKPN GHIANRLEVD SNTSSQSSNS 
ESETEDERVG EDTPFLGIQN PLAASLEATP AFRLADSRTN PAGRFSTQEE IQARLSSVIA 
NQDPIAV

Genular Protein ID: 1492584366

Symbol: B0FYA9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FYA9

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 458
  • Mass: 50555
  • Checksum: F092E3E0F16F9BBB
  • Sequence:
    • SERKEGRGKG KGKKKERGSG KKPESAAGSQ SPALPPRLKE MKSQESAAGS KLVLRCETSS 
EYSSLRFKWF KNGNELNRKN KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND 
SASANITIVE SNEIITGMPA STEGAYVSSE SPIRISVSTE GANTSSSTST STTGTSHLVK 
CAEKEKTFCV NGGECFMVKD LSNPSRYLCK CPNEFTGDRC QNYVMASFYK AEELYQKRVL 
TITGICIALL VVGIMCVVAY CKTKKQRKKL HDRLRQSLRS ERNNMMNIAN GPHHPNPPPE 
NVQLVNQYVS KNVISSEHIV EREAETSFST SHYTSTAHHS TTVTQTPSHS WSNGHTESIL 
SESHSVIVMS SVENSRHSSP TGGPRGRLNG TGGPRECNSF LRHARETPDS YRDSPHSERH 
NLIAELRRNK AHRSKCMQIQ LSATHLRSSS IPHLGFIL

Genular Protein ID: 631951702

Symbol: B0FYA7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FYA7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 193
  • Mass: 20891
  • Checksum: 8403AAC43EE97A77
  • Sequence:
    • SERKEGRGKG KGKKKERGSG KKPESAAGSQ SPALPPRLKE MKSQESAAGS KLVLRCETSS 
EYSSLRFKWF KNGNELNRKN KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND 
SASANITIVE SNEIITGMPA STEGAYVSSA TSTSTTGTSH LVKCAEKEKT FCVNGGECFM 
VKDLSNPSRY LCK

Genular Protein ID: 555233387

Symbol: B0FWZ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0FWZ3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 206
  • Mass: 22584
  • Checksum: A564911EBD44BBBA
  • Sequence:
    • SERKEGRGKG KGKKKERGSG KKPESAAGSQ SPALPPRLKE MKSQESAAGS KLVLRCETSS 
EYSSLRFKWF KNGNELNRKN KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND 
SASANITIVE SNATSTSTTG TSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE 
FTGDRCQNYV MASFYSTSTP FLSLPE

Genular Protein ID: 2359396937

Symbol: A0A494C0L9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C0L9

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 522
  • Mass: 57187
  • Checksum: 10FC2FEC84D14F3D
  • Sequence:
    • MEIYSPDMSE VAAERSSSPS TQLSADPSLD GLPAAEDMPE PQTEDGRTPG LVGLAVPCCA 
CLEAERLRGC LNSEKICIVP ILACLVSLCL CIAGLKWVFV DKIFEYDSPT HLDPGGLGQD 
PIISLDATAA SAVWVSSEAY TSPVSRAQSE SEVQVTVQGD KAVVSFEPSA APTPKNRIFA 
FSFLPSTAPS FPSPTRNPEV RTPKSATQPQ TTETNLQTAP KLSTSTSTTG TSHLVKCAEK 
EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI EFMEAEELYQ 
KRVLTITGIC IALLVVGIMC VVAYCKTKKQ RKKLHDRLRQ SLRSERNNMM NIANGPHHPN 
PPPENVQLVN QYVSKNVISS EHIVEREAET SFSTSHYTST AHHSTTVTQT PSHSWSNGHT 
ESILSESHSV IVMSSVENSR HSSPTGGPRG RLNGTGGPRE CNSFLRHARE TPDSYRDSPH 
SERHNLIAEL RRNKAHRSKC MQIQLSATHL RSSSIPHLGF IL

Genular Protein ID: 4147666440

Symbol: Q7RTW5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7RTW5

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12145742

Title: Neuregulin 1 and susceptibility to Schizophrenia.

PubMed ID: 12145742

DOI: 10.1086/342734

Sequence Information:

  • Length: 211
  • Mass: 22755
  • Checksum: E9EA8BF45F2A1090
  • Sequence:
    • MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS 
SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 
DSASANITIV ESNEIITGMP ASTEGAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLV 
KCAEKEKTFC VNGGECFMVK DLSNPSRYLC K

Genular Protein ID: 1826062535

Symbol: A0A494C114_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C114

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 207
  • Mass: 22715
  • Checksum: 9E78DF98A10A2B5D
  • Sequence:
    • MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS 
SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 
DSASANITIV ESNATSTSTT GTSHLVKCAE KEKTFCVNGG ECFMVKDLSN PSRYLCKCPN 
EFTGDRCQNY VMASFYSTST PFLSLPE

Genular Protein ID: 3722189525

Symbol: Q7RTW3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7RTW3

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 3 SUPFAM 2

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12145742

Title: Neuregulin 1 and susceptibility to Schizophrenia.

PubMed ID: 12145742

DOI: 10.1086/342734

Sequence Information:

  • Length: 637
  • Mass: 70169
  • Checksum: 0B89DF6E2ED70333
  • Sequence:
    • MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS 
SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 
DSASANITIV ESNEIITGMP ASTEGAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLV 
KCAEKEKTFC VNGGECFMVK DLSNPSRYLC KCPNEFTGDR CQNYVMASFY KAEELYQKRV 
LTITGICIAL LVVGIMCVVA YCKTKKQRKK LHDRLRQSLR SERNNTMNIA NGPHHPNPPP 
ENVQLVNQYV SKNVISSEHI VEREAETSFS TSHYTSTAHH STTVTQTPSH SWSNGHTESI 
LSESHSVIVM SSVENSRHSS PTGGPRGRLN GTGGPRECNS FLRHARETPD SYRDSPHSER 
YVSAMTTPAR MSPVDFHTPS SPKSPPSEMS PPVSSMTVSM PSMAVSPFME EERPLLLVTP 
PRLREKKFDH HPQQFSSFHH NPAHDSNSLP ASPLRIVEDE EYETTQEYEP AQEPVKKLAN 
SRRAKRTKPN GHIANRLEVD SNTSSQSSNS ESETEDERVG EDTPFLGIQN PLAASLEATP 
AFRLADSRTN PAGRFSTQEE IQARLSSVIA NQDPIAV

Genular Protein ID: 2857960868

Symbol: E5RHP6_HUMAN

Name: N/A

UniProtKB Accession Codes:

E5RHP6

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 ChiTaRS 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 308
  • Mass: 34404
  • Checksum: 915B562729A4339C
  • Sequence:
    • MQIPKHISIE DITATSTSTT GTSHLVKCAE KEKTFCVNGG ECFMVKDLSN PSRYLCKCQP 
GFTGARCTEN VPMKVQNQEK AEELYQKRVL TITGICIALL VVGIMCVVAY CKTKKQRKKL 
HDRLRQSLRS ERNNMMNIAN GPHHPNPPPE NVQLVNQYVS KNVISSEHIV EREAETSFST 
SHYTSTAHHS TTVTQTPSHS WSNGHTESIL SESHSVIVMS SVENSRHSSP TGGPRGRLNG 
TGGPRECNSF LRHARETPDS YRDSPHSERH NLIAELRRNK AHRSKCMQIQ LSATHLRSSS 
IPHLGFIL

Genular Protein ID: 1474044368

Symbol: B7Z1D7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1D7

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 308
  • Mass: 34403
  • Checksum: 99F17E85A38C99BC
  • Sequence:
    • MQIPKHISIE DITATSTSTT GTSHLVKCAE KEKTFCVNGG ECFMVKDLSN PSRYLCKCQP 
GFTGARCTEN VPMKVQNQEK AEELYQKRVL TITGICIALL VVGIMCVVAY CKTKKQRKKL 
HDRLRQSLRS ERNNMMNIAN GPHHPNPPPE NVQLVNQYVS KNVISSEHIV EREAETSFST 
SHYTSTAHHS TTVTQTPSHS WSNGHTESIL SKSHSVIVMS SVENSRHSSP TGGPRGRLNG 
TGGPRECNSF LRHARETPDS YRDSPHSERH NLIAELRRNK AHRSKCMQIQ LSATHLRSSS 
IPHLGFIL

Genular Protein ID: 1836933263

Symbol: A0A024QY88_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A024QY88

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 ExpressionAtlas 1 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 Pfam 1 RefSeq 1 SAM 1 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12145742

Title: Neuregulin 1 and susceptibility to Schizophrenia.

PubMed ID: 12145742

DOI: 10.1086/342734

Sequence Information:

  • Length: 241
  • Mass: 26143
  • Checksum: D2450DB340E6B64D
  • Sequence:
    • MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS 
SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 
DSASANITIV ESNEIITGMP ASTEGAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLV 
KCAEKEKTFC VNGGECFMVK DLSNPSRYLC KCPNEFTGDR CQNYVMASFY STSTPFLSLP 
E

Genular Protein ID: 3297373727

Symbol: B7Z1E3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1E3

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 GenomeRNAi 1 InterPro 4 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 483
  • Mass: 53725
  • Checksum: 39B94B909F1D3DE0
  • Sequence:
    • MQIPKHISIE DITATSTSTT GTSHLVKCAE KEKTFCVNGG ECFMVKDLSN PSRYLCKCPN 
EFTGDRCQNY VMASFYKAEE LYQKRVLTIT GICIALLVVG IMCVVAYCKT KKQRKKLHDR 
LRQSLRSERN NMMNIANGPH HPNPPPENVQ LVNQYVSKNV ISSEHIVERE AETSFSTSHY 
TSTAHHSTTV TQTPSHSWSN GHTESILSES HSVIVMSSVE NSRHSSPTGG PRGRLNGTGG 
PRECNSFLRH ARETPDSYRD SPHSERYVSA MTTPARMSPV DFHTPSSPKS PPSEMSPPVS 
SMTVSMPSMA VSPFMEEERP LLLVTPPRLR EKKFDHHPQQ FSSFHHNPAH DSNSLPASPL 
RIVEDEEYET TQEYEPAQEP VKKLANSRRA KRTKPNGHIA NRLEVDSNTS SQSSNSESET 
EDERVGEDTP FLGIQNPLAA SLEATPAFRL ADSRTNPAGR FSTQEEIQAR LSSVIANQDP 
IAV

Genular Protein ID: 2759538833

Symbol: A6MW56_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6MW56

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 3 SUPFAM 2

Citations:

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.M702953200

Sequence Information:

  • Length: 481
  • Mass: 53253
  • Checksum: 0E5B8B7386B8A340
  • Sequence:
    • MGKGRAGRVG TTALPPRLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNEIITGMPA 
STEGAYVSSA ASTSTTGTSH LVKCAEKEKT FCVNGGECFM VKDLSNPSRY LCKCPNEFTG 
DRCQNYVMAS FYKHLGIEFM EAEELYQKRV LTITGICIAL LVVGIMCVVA YCKTKKQRKK 
LHDRLRQSPR SERNNTMNIA NGPHHPNPPP ENVQLVNQYV SKNVISSEHI VEREAETSFP 
TSHYTSTAHH STTVTQTPSH SWSNGHTESI LSESHSVIVM SSVENSRHSS PTGGPRGRLN 
GTGGPRECNS YLRHARETPD SYRDSPHSER YVSVMTTPAR MSPVDFHTPS SPKSPPSEMS 
PPVSSMTVSM PSMAVSPFME EERPLLLVTP PRLREKKFDH HPQQFSSFHH NPAHDSNSLP 
A

Genular Protein ID: 2496105669

Symbol: A5YAK8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YAK8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 17565985

Title: Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

PubMed ID: 17565985

DOI: 10.1074/jbc.M702953200

Sequence Information:

  • Length: 197
  • Mass: 21422
  • Checksum: 817A13843DF40CEE
  • Sequence:
    • MGKGRAGRVG TTALPPRLKE MKSQESAAGS KLVLRCETSS EYSSLRFKWF KNGNELNRKN 
KPQNIKIQKK PGKSELRINK ASLADSGEYM CKVISKLGND SASANITIVE SNATSTSTTG 
TSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKGGGA VPEESADHNR HLHRPPCGRH 
HVFGGLLQNQ ETAEKAA

Genular Protein ID: 990649744

Symbol: E3SFM9_HUMAN

Name: N/A

UniProtKB Accession Codes:

E3SFM9

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 5 SAM 2 SMART 3 SUPFAM 2

Citations:

PubMed ID: 20218976

Title: Molecular and cellular characterization of Neuregulin-1 type IV isoforms.

PubMed ID: 20218976

DOI: 10.1111/j.1471-4159.2010.06677.x