Details for: HIC1

Gene ID: 3090

Symbol: HIC1

Ensembl ID: ENSG00000177374

Description: HIC ZBTB transcriptional repressor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 61.6541
    Cell Significance Index: -9.5900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 37.7301
    Cell Significance Index: -9.5700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 21.1492
    Cell Significance Index: -9.9900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 20.1843
    Cell Significance Index: -8.2000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.7353
    Cell Significance Index: -8.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.7862
    Cell Significance Index: -9.6000
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 2.9805
    Cell Significance Index: 24.6500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.5011
    Cell Significance Index: -6.7000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4075
    Cell Significance Index: -9.5000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.3902
    Cell Significance Index: 30.6100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.3189
    Cell Significance Index: 68.7000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.2541
    Cell Significance Index: 26.2500
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 0.8604
    Cell Significance Index: 5.0800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7170
    Cell Significance Index: 98.4600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.6538
    Cell Significance Index: 4.0500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.6492
    Cell Significance Index: 10.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6311
    Cell Significance Index: 18.0900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3259
    Cell Significance Index: 6.3600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.3081
    Cell Significance Index: 5.4500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.2738
    Cell Significance Index: 2.6400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2648
    Cell Significance Index: 5.7400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2310
    Cell Significance Index: 43.9600
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: 0.1861
    Cell Significance Index: 1.1400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.1738
    Cell Significance Index: 1.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1442
    Cell Significance Index: 7.2900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1219
    Cell Significance Index: 110.0300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1156
    Cell Significance Index: 11.4400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0810
    Cell Significance Index: 10.3900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0723
    Cell Significance Index: 45.1500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0722
    Cell Significance Index: 49.9200
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 0.0593
    Cell Significance Index: 0.4400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0481
    Cell Significance Index: 7.8200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0397
    Cell Significance Index: 0.6700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0320
    Cell Significance Index: 0.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0195
    Cell Significance Index: 3.8600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0160
    Cell Significance Index: 1.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0006
    Cell Significance Index: 0.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0017
    Cell Significance Index: -0.0600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0027
    Cell Significance Index: -5.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0032
    Cell Significance Index: -5.8500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0039
    Cell Significance Index: -6.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0049
    Cell Significance Index: -6.7200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0055
    Cell Significance Index: -4.0700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0059
    Cell Significance Index: -0.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0096
    Cell Significance Index: -5.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0104
    Cell Significance Index: -4.6200
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0108
    Cell Significance Index: -0.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0120
    Cell Significance Index: -7.6300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0121
    Cell Significance Index: -8.8800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0128
    Cell Significance Index: -9.6800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0132
    Cell Significance Index: -7.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0159
    Cell Significance Index: -0.7200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0165
    Cell Significance Index: -1.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0172
    Cell Significance Index: -0.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0180
    Cell Significance Index: -8.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0183
    Cell Significance Index: -3.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0232
    Cell Significance Index: -8.3100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0254
    Cell Significance Index: -4.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0261
    Cell Significance Index: -4.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0283
    Cell Significance Index: -8.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0305
    Cell Significance Index: -3.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0315
    Cell Significance Index: -1.9300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0347
    Cell Significance Index: -6.9700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0376
    Cell Significance Index: -2.6000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0584
    Cell Significance Index: -8.4900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0638
    Cell Significance Index: -8.2400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0653
    Cell Significance Index: -3.0700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0733
    Cell Significance Index: -4.4000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0792
    Cell Significance Index: -6.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0825
    Cell Significance Index: -9.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0845
    Cell Significance Index: -9.9600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0849
    Cell Significance Index: -8.6800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0854
    Cell Significance Index: -6.0400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0867
    Cell Significance Index: -9.0300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0877
    Cell Significance Index: -0.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0932
    Cell Significance Index: -6.0100
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.1102
    Cell Significance Index: -0.6900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1122
    Cell Significance Index: -5.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1138
    Cell Significance Index: -9.0200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1178
    Cell Significance Index: -6.1200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1195
    Cell Significance Index: -3.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1208
    Cell Significance Index: -9.0000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1350
    Cell Significance Index: -5.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1407
    Cell Significance Index: -7.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1428
    Cell Significance Index: -9.0000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1433
    Cell Significance Index: -8.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1446
    Cell Significance Index: -9.7200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1471
    Cell Significance Index: -3.9400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1671
    Cell Significance Index: -2.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1750
    Cell Significance Index: -9.8200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1812
    Cell Significance Index: -2.6000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1862
    Cell Significance Index: -2.5400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1866
    Cell Significance Index: -2.1200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1926
    Cell Significance Index: -4.9500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1972
    Cell Significance Index: -6.3200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2011
    Cell Significance Index: -3.0300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.2077
    Cell Significance Index: -5.1800
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2081
    Cell Significance Index: -1.4100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2090
    Cell Significance Index: -9.0900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2130
    Cell Significance Index: -9.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** HIC1 is a transcriptional repressor that belongs to the ZBTB family of proteins. It possesses a characteristic zinc finger DNA-binding domain, which enables it to bind to specific DNA sequences. HIC1's primary function is to repress transcription by interacting with RNA polymerase II and histone deacetylases, thereby inhibiting the expression of target genes. Additionally, HIC1 can regulate the Wnt signaling pathway and DNA damage response, modulating cell growth, proliferation, and survival. **Pathways and Functions** HIC1's regulatory activities are mediated through its interactions with various cellular pathways, including: 1. **Chromatin and DNA-binding transcription factor activity**: HIC1 binds to specific DNA sequences, recruiting histone deacetylases and RNA polymerase II to modulate chromatin structure and transcriptional activity. 2. **Intrinsic apoptotic signaling pathway in response to DNA damage**: HIC1 can regulate the expression of pro-apoptotic and anti-apoptotic genes, influencing cell survival and death in response to DNA damage. 3. **Metabolism of proteins**: HIC1 may interact with proteins involved in protein degradation, influencing cellular protein homeostasis. 4. **Wnt signaling pathway**: HIC1 can modulate the Wnt signaling pathway, which is involved in cell proliferation, differentiation, and survival. 5. **Negative regulation of transcription by RNA polymerase II**: HIC1 inhibits the activity of RNA polymerase II, a key enzyme responsible for transcription. **Clinical Significance** Dysregulation of HIC1 expression has been implicated in various diseases, including: 1. **Cancer**: HIC1 is frequently hypermethylated and silenced in tumors, leading to the loss of tumor suppressor function. 2. **Neurodegenerative diseases**: HIC1 expression has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's, where it may contribute to neuronal death and disease progression. 3. **Autoimmune diseases**: HIC1 may play a role in autoimmune diseases, such as multiple sclerosis, where it influences the regulation of immune cell function and tissue damage. In conclusion, HIC1 is a critical regulator of cellular processes, including transcription, DNA damage response, and apoptosis. Its dysregulation has been implicated in various diseases, highlighting the importance of HIC1 as a potential therapeutic target.

Genular Protein ID: 1975442005

Symbol: HIC1_HUMAN

Name: Hypermethylated in cancer 1 protein

UniProtKB Accession Codes:

Q14526 D3DTI4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 4 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7585125

Title: p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3.

PubMed ID: 7585125

DOI: 10.1038/nm0695-570

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 10611298

Title: Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B.

PubMed ID: 10611298

DOI: 10.1073/pnas.96.26.14831

PubMed ID: 11554746

Title: Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.

PubMed ID: 11554746

DOI: 10.1006/bbrc.2001.5624

PubMed ID: 12052894

Title: The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.

PubMed ID: 12052894

DOI: 10.1128/mcb.22.13.4890-4901.2002

PubMed ID: 15231840

Title: The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties.

PubMed ID: 15231840

DOI: 10.1074/jbc.m401610200

PubMed ID: 16269335

Title: Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.

PubMed ID: 16269335

DOI: 10.1016/j.cell.2005.08.011

PubMed ID: 16690027

Title: Mechanism of fibroblast growth factor-binding protein 1 repression by TGF-beta.

PubMed ID: 16690027

DOI: 10.1016/j.bbrc.2006.04.052

PubMed ID: 16724116

Title: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.

PubMed ID: 16724116

DOI: 10.1038/sj.emboj.7601147

PubMed ID: 16762039

Title: A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.

PubMed ID: 16762039

DOI: 10.1111/j.1742-4658.2006.05301.x

PubMed ID: 17283066

Title: An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.

PubMed ID: 17283066

DOI: 10.1128/mcb.01098-06

PubMed ID: 17213307

Title: Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex.

PubMed ID: 17213307

DOI: 10.1073/pnas.0610590104

PubMed ID: 25646486

Title:

PubMed ID: 25646486

DOI: 10.1073/pnas.1501052112

PubMed ID: 18347096

Title: Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.

PubMed ID: 18347096

DOI: 10.1101/gad.1640908

PubMed ID: 19486893

Title: HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.

PubMed ID: 19486893

DOI: 10.1016/j.bbrc.2009.05.115

PubMed ID: 19525223

Title: Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

PubMed ID: 19525223

DOI: 10.1074/jbc.m109.022350

PubMed ID: 20547755

Title: Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells.

PubMed ID: 20547755

DOI: 10.1128/mcb.00582-09

PubMed ID: 20154726

Title: A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.

PubMed ID: 20154726

DOI: 10.1038/onc.2010.12

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 733
  • Mass: 76508
  • Checksum: 6DDD0F49C4E490D3
  • Sequence:
    • MTFPEADILL KSGECAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA 
HKNVLAASSA YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLADGA EAAAAAAVAP 
GAEPSLGAVL AAASYLQIPD LVALCKKRLK RHGKYCHLRG GGGGGGGYAP YGRPGRGLRA 
ATPVIQACYP SPVGPPPPPA AEPPSGPEAA VNTHCAELYA SGPGPAAALC ASERRCSPLC 
GLDLSKKSPP GSAAPERPLA ERELPPRPDS PPSAGPAAYK EPPLALPSLP PLPFQKLEEA 
APPSDPFRGG SGSPGPEPPG RPDGPSLLYR WMKHEPGLGS YGDELGRERG SPSERCEERG 
GDAAVSPGGP PLGLAPPPRY PGSLDGPGAG GDGDDYKSSS EETGSSEDPS PPGGHLEGYP 
CPHLAYGEPE SFGDNLYVCI PCGKGFPSSE QLNAHVEAHV EEEEALYGRA EAAEVAAGAA 
GLGPPFGGGG DKVAGAPGGL GELLRPYRCA SCDKSYKDPA TLRQHEKTHW LTRPYPCTIC 
GKKFTQRGTM TRHMRSHLGL KPFACDACGM RFTRQYRLTE HMRIHSGEKP YECQVCGGKF 
AQQRNLISHM KMHAVGGAAG AAGALAGLGG LPGVPGPDGK GKLDFPEGVF AVARLTAEQL 
SLKQQDKAAA AELLAQTTHF LHDPKVALES LYPLAKFTAE LGLSPDKAAE VLSQGAHLAA 
GPDGRTIDRF SPT

Genular Protein ID: 3532470486

Symbol: A0PJI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0PJI1

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 141
  • Mass: 15222
  • Checksum: 1B780DC577812D29
  • Sequence:
    • RGEDGPAGQT DRGPGGRRAA QPRPPWIRRQ PGPGLSTCPP GECAGQTMLD TMEAPGHSRQ 
LLLQLNNQRT KGFLCDVIIV VQNALFRAHK NVLAASSAYL KSLVVHDNLL NLDHDMVSPA 
VFRLVLDFIY TGRLADGAEA A

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.