Details for: HSPD1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 7.76
Marker Score: 137,835 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 4.12
Marker Score: 4,297 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 3.95
Marker Score: 3,371 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.91
Marker Score: 133,006 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.6
Marker Score: 8,793 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.57
Marker Score: 3,814 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.1
Marker Score: 20,133 - Cell Name: radial glial cell (CL0000681)
Fold Change: 3.05
Marker Score: 1,124 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.97
Marker Score: 39,167 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.9
Marker Score: 1,208 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.88
Marker Score: 99,691 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 2.88
Marker Score: 2,252 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 2.84
Marker Score: 10,092 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 2.83
Marker Score: 4,005 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 2.81
Marker Score: 4,892 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 2.78
Marker Score: 2,107 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 2.78
Marker Score: 7,438 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 2.76
Marker Score: 13,565 - Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 2.74
Marker Score: 2,065 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 2.7
Marker Score: 4,157 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.69
Marker Score: 2,115 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.68
Marker Score: 5,588 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 2.67
Marker Score: 2,102 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.64
Marker Score: 1,659 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 2.64
Marker Score: 844 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.62
Marker Score: 4,299 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.61
Marker Score: 2,200 - Cell Name: theca cell (CL0000503)
Fold Change: 2.6
Marker Score: 1,860 - Cell Name: pro-T cell (CL0000827)
Fold Change: 2.58
Marker Score: 10,540 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 2.57
Marker Score: 15,259 - Cell Name: oogonial cell (CL0000024)
Fold Change: 2.53
Marker Score: 3,643 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 2.53
Marker Score: 18,858 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 2.53
Marker Score: 2,377 - Cell Name: neural crest cell (CL0011012)
Fold Change: 2.53
Marker Score: 2,699 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 2.51
Marker Score: 827 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 2.51
Marker Score: 3,027 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.5
Marker Score: 4,251 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.48
Marker Score: 2,910 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.47
Marker Score: 1,407 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 2.46
Marker Score: 6,691 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.45
Marker Score: 24,696 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 2.43
Marker Score: 1,214 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.42
Marker Score: 1,086 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.42
Marker Score: 4,282 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.4
Marker Score: 27,051 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.4
Marker Score: 1,600 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.39
Marker Score: 5,636 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.39
Marker Score: 2,517 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 2.38
Marker Score: 2,395 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.38
Marker Score: 899 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 2.35
Marker Score: 2,827 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.35
Marker Score: 561 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.35
Marker Score: 6,966 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.35
Marker Score: 1,056 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.34
Marker Score: 3,882 - Cell Name: renal intercalated cell (CL0005010)
Fold Change: 2.34
Marker Score: 1,249 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 2.34
Marker Score: 1,692 - Cell Name: Unknown (CL0002371)
Fold Change: 2.33
Marker Score: 2,479 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 2.33
Marker Score: 20,255 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.33
Marker Score: 3,275 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 2.33
Marker Score: 4,154 - Cell Name: mature T cell (CL0002419)
Fold Change: 2.33
Marker Score: 23,027 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 2.32
Marker Score: 2,452 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 2.32
Marker Score: 8,581 - Cell Name: memory B cell (CL0000787)
Fold Change: 2.31
Marker Score: 1,751 - Cell Name: Leydig cell (CL0000178)
Fold Change: 2.31
Marker Score: 2,491 - Cell Name: stem cell (CL0000034)
Fold Change: 2.3
Marker Score: 5,473 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.3
Marker Score: 4,323 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.29
Marker Score: 6,437 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 2.29
Marker Score: 1,051 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.29
Marker Score: 9,874 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 2.28
Marker Score: 1,644 - Cell Name: blood cell (CL0000081)
Fold Change: 2.27
Marker Score: 26,443 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 2.27
Marker Score: 1,308 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.26
Marker Score: 3,329 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 2.26
Marker Score: 877 - Cell Name: hepatocyte (CL0000182)
Fold Change: 2.25
Marker Score: 1,535 - Cell Name: basal cell (CL0000646)
Fold Change: 2.24
Marker Score: 2,897 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.24
Marker Score: 7,021 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.22
Marker Score: 8,743 - Cell Name: pro-B cell (CL0000826)
Fold Change: 2.22
Marker Score: 2,142 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.22
Marker Score: 4,429 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.22
Marker Score: 2,410 - Cell Name: erythroblast (CL0000765)
Fold Change: 2.21
Marker Score: 1,379 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 2.21
Marker Score: 1,467 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.2
Marker Score: 706 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 2.19
Marker Score: 2,322 - Cell Name: ependymal cell (CL0000065)
Fold Change: 2.18
Marker Score: 759 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 2.17
Marker Score: 1,144 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.16
Marker Score: 8,339 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.16
Marker Score: 982 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 2.15
Marker Score: 1,055 - Cell Name: epithelial cell (CL0000066)
Fold Change: 2.15
Marker Score: 3,420 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.15
Marker Score: 3,455 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.15
Marker Score: 4,895 - Cell Name: Unknown (CL0000548)
Fold Change: 2.13
Marker Score: 1,555 - Cell Name: plasmablast (CL0000980)
Fold Change: 2.13
Marker Score: 2,837 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 2.12
Marker Score: 529 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 2.11
Marker Score: 996 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 2.11
Marker Score: 529
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2962778335
Symbol: CH60_HUMAN
Name: 60 kDa heat shock protein, mitochondrial
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2568584
Title: Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.
PubMed ID: 2568584
PubMed ID: 1980192
Title: Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families.
PubMed ID: 1980192
PubMed ID: 12483302
Title: Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter.
PubMed ID: 12483302
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2907406
Title: Amino-acid sequence homology of a polymorphic cellular protein from human lymphocytes and the chaperonins from Escherichia coli (groEL) and chloroplasts (Rubisco-binding protein).
PubMed ID: 2907406
PubMed ID: 2079031
Title: Development of a database of amino acid sequences for human colon carcinoma proteins separated by two-dimensional polyacrylamide gel electrophoresis.
PubMed ID: 2079031
PubMed ID: 1731090
Title: Complex formation of human T-cell leukemia virus type I p40tax transactivator with cellular polypeptides.
PubMed ID: 1731090
PubMed ID: 9150946
Title: Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2.
PubMed ID: 9150946
PubMed ID: 7895732
Title: The human myocardial two-dimensional gel protein database: update 1994.
PubMed ID: 7895732
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 1286669
Title: Human liver protein map: a reference database established by microsequencing and gel comparison.
PubMed ID: 1286669
PubMed ID: 15242332
Title: Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.
PubMed ID: 15242332
DOI: 10.1042/bj20040647
PubMed ID: 9150948
Title: A two-dimensional gel database of human colon carcinoma proteins.
PubMed ID: 9150948
PubMed ID: 1972619
Title: Mitochondrial import of the human chaperonin (HSP60) protein.
PubMed ID: 1972619
PubMed ID: 1346131
Title: Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring.
PubMed ID: 1346131
PubMed ID: 11422376
Title: The effect of nucleotides and mitochondrial chaperonin 10 on the structure and chaperone activity of mitochondrial chaperonin 60.
PubMed ID: 11422376
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 15120623
Title: Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis.
PubMed ID: 15120623
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21908771
Title: The first identification of lysine malonylation substrates and its regulatory enzyme.
PubMed ID: 21908771
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 22664726
Title: ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.
PubMed ID: 22664726
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23349634
Title: A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
PubMed ID: 23349634
PubMed ID: 24286120
Title: GTP binding controls complex formation by the human ROCO protein MASL1.
PubMed ID: 24286120
DOI: 10.1111/febs.12593
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 25918392
Title: Crystal structure of the human mitochondrial chaperonin symmetrical football complex.
PubMed ID: 25918392
PubMed ID: 11898127
Title: Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60.
PubMed ID: 11898127
DOI: 10.1086/339935
PubMed ID: 18571143
Title: Mitochondrial Hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy.
PubMed ID: 18571143
Sequence Information:
- Length: 573
- Mass: 61055
- Checksum: E51E1BAD9615899C
- Sequence:
MLRLPTVFRQ MRPVSRVLAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ DAYVLLSEKK ISSIQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL TLNLEDVQPH DLGKVGEVIV TKDDAMLLKG KGDKAQIEKR IQEIIEQLDV TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR VTDALNATRA AVEEGIVLGG GCALLRCIPA LDSLTPANED QKIGIEIIKR TLKIPAMTIA KNAGVEGSLI VEKIMQSSSE VGYDAMAGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG GMF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.