Details for: JAK1

Gene ID: 3716

Symbol: JAK1

Ensembl ID: ENSG00000162434

Description: Janus kinase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 3.22
    Marker Score: 7855
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 3.18
    Marker Score: 10030
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.13
    Marker Score: 8778.5
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.1
    Marker Score: 12980
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.07
    Marker Score: 4521
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.07
    Marker Score: 6731
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 3.07
    Marker Score: 3528
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 3.02
    Marker Score: 2476
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 3.01
    Marker Score: 1297.5
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3
    Marker Score: 101906
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 2.97
    Marker Score: 8657.5
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.95
    Marker Score: 12632
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.92
    Marker Score: 2741
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 2.86
    Marker Score: 28346
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 2.85
    Marker Score: 3166
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.84
    Marker Score: 150249
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.83
    Marker Score: 3908
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.83
    Marker Score: 60428
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.82
    Marker Score: 1570.5
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.8
    Marker Score: 2456
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.77
    Marker Score: 24346
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.76
    Marker Score: 2087
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.7
    Marker Score: 1541
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.7
    Marker Score: 788
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 2.61
    Marker Score: 860
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 2.61
    Marker Score: 5476
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 2.58
    Marker Score: 1589
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.58
    Marker Score: 1287
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.58
    Marker Score: 1043.5
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.57
    Marker Score: 19701.5
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 2.56
    Marker Score: 2186.5
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.55
    Marker Score: 96941
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.53
    Marker Score: 1983
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.52
    Marker Score: 797
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 2.5
    Marker Score: 633
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.49
    Marker Score: 37297
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.49
    Marker Score: 869
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.49
    Marker Score: 1812
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.48
    Marker Score: 2102
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.47
    Marker Score: 1866
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.46
    Marker Score: 6806.5
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 2.46
    Marker Score: 2970
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2.45
    Marker Score: 758
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.43
    Marker Score: 580.5
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.43
    Marker Score: 2274
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.42
    Marker Score: 2096
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.42
    Marker Score: 1862
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.42
    Marker Score: 1407
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.41
    Marker Score: 47961.5
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 2.41
    Marker Score: 1411
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.4
    Marker Score: 998
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.38
    Marker Score: 1254
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.36
    Marker Score: 2859
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 2.36
    Marker Score: 512.5
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.35
    Marker Score: 2319.5
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.34
    Marker Score: 2226.5
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 2.33
    Marker Score: 1707
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.33
    Marker Score: 2532
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.32
    Marker Score: 2447
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.31
    Marker Score: 2489
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.31
    Marker Score: 2227
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.28
    Marker Score: 1364
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.28
    Marker Score: 1922
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.28
    Marker Score: 1372
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 2.27
    Marker Score: 789
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.27
    Marker Score: 6736
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 2.25
    Marker Score: 4025
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.25
    Marker Score: 2066.5
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 2.21
    Marker Score: 753
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 2.2
    Marker Score: 10791
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 2.19
    Marker Score: 2589.5
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 2.18
    Marker Score: 499.5
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.18
    Marker Score: 1952
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 2.17
    Marker Score: 1806
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.17
    Marker Score: 5204.5
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 2.17
    Marker Score: 758
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.17
    Marker Score: 3151
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 2.17
    Marker Score: 2177
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.16
    Marker Score: 120710
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.16
    Marker Score: 3762
  • Cell Name: centroblast (CL0009112)
    Fold Change: 2.15
    Marker Score: 1060
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 2.15
    Marker Score: 14002
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.14
    Marker Score: 8292.5
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.14
    Marker Score: 7599
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 2.14
    Marker Score: 1439
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.13
    Marker Score: 78599
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.13
    Marker Score: 1059
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.13
    Marker Score: 1246
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.12
    Marker Score: 3763
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.12
    Marker Score: 24625
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.11
    Marker Score: 748
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 2.11
    Marker Score: 2273
  • Cell Name: pericyte (CL0000669)
    Fold Change: 2.11
    Marker Score: 1234
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 2.09
    Marker Score: 1518
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 2.09
    Marker Score: 635
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.08
    Marker Score: 2301
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 2.08
    Marker Score: 407
  • Cell Name: type I enteroendocrine cell (CL0002277)
    Fold Change: 2.07
    Marker Score: 515.5
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 2.07
    Marker Score: 4028
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.07
    Marker Score: 8569

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Other Information

**Key characteristics:** * JAK1 is a Janus kinase, meaning it can act as a kinase or a GTPase. * It is a key regulator of the adaptive immune response. * It is involved in the regulation of inflammation, cell growth, and differentiation. **Pathways and functions:** * JAK1 is involved in the antiviral mechanism of interferons. * It is also involved in the regulation of cytokine signaling, immune cell activation, and inflammation. * It plays a role in the regulation of the immune response to viral infection. **Clinical significance:** * Mutations in the JAK1 gene have been linked to an increased risk of autoimmune diseases, cancer, and viral infections. * Targeting JAK1 has been explored as a therapeutic strategy for these diseases. **Additional points:** * JAK1 is a key regulator of the innate immune response. * It is also involved in the regulation of adaptive immune responses. * It is a well-studied target for cancer immunotherapy.

Genular Protein ID: 2658596508

Symbol: JAK1_HUMAN

Name: Tyrosine-protein kinase JAK1

UniProtKB Accession Codes:

P23458 Q59GQ2 Q9UD26

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CORUM 1 CPTAC 3 CPTC 1 CTD 1 CarbonylDB 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 ComplexPortal 21 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 12 DrugCentral 1 EC 1 EMBL 5 EPD 1 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 39 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 17 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 59 PDBsum 50 PIR 1 PIRSF 1 PRINTS 3 PRO 1 PROSITE 5 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 28 RefSeq 7 Rhea 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1848670

Title: Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

PubMed ID: 1848670

DOI: 10.1128/mcb.11.4.2057-2065.1991

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8247543

Title: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.

PubMed ID: 8247543

PubMed ID: 7896447

Title: Receptor tyrosine kinases expressed in metastatic colon cancer.

PubMed ID: 7896447

DOI: 10.1002/ijc.2910600611

PubMed ID: 8232552

Title: The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.

PubMed ID: 8232552

DOI: 10.1038/366129a0

PubMed ID: 7615558

Title: The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors.

PubMed ID: 7615558

DOI: 10.1074/jbc.270.29.17528

PubMed ID: 7657660

Title: Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor.

PubMed ID: 7657660

DOI: 10.1074/jbc.270.35.20775

PubMed ID: 7759950

Title: Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor.

PubMed ID: 7759950

DOI: 10.1002/jlb.57.5.712

PubMed ID: 12200137

Title: IL-2 receptor signaling through the Shb adapter protein in T and NK cells.

PubMed ID: 12200137

DOI: 10.1016/s0006-291x(02)02016-8

PubMed ID: 11909529

Title: The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.

PubMed ID: 11909529

DOI: 10.1016/s0960-9822(02)00697-8

PubMed ID: 12133952

Title: Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors.

PubMed ID: 12133952

DOI: 10.4049/jimmunol.169.3.1302

PubMed ID: 15194700

Title: Characterization of the signaling capacities of the novel gp130-like cytokine receptor.

PubMed ID: 15194700

DOI: 10.1074/jbc.m401122200

PubMed ID: 15277531

Title: Jamip1 (marlin-1) defines a family of proteins interacting with Janus kinases and microtubules.

PubMed ID: 15277531

DOI: 10.1074/jbc.m401915200

PubMed ID: 16239216

Title: JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

PubMed ID: 16239216

DOI: 10.1074/jbc.c500358200

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26027934

Title: Downregulation of the ubiquitin ligase RNF125 underlies resistance of melanoma cells to BRAF inhibitors via JAK1 deregulation.

PubMed ID: 26027934

DOI: 10.1016/j.celrep.2015.04.049

PubMed ID: 28111307

Title: JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome.

PubMed ID: 28111307

DOI: 10.1016/j.jaci.2016.12.957

PubMed ID: 19361440

Title: Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

PubMed ID: 19361440

DOI: 10.1016/j.jmb.2009.01.041

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 32750333

Title: Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function.

PubMed ID: 32750333

DOI: 10.1016/j.immuni.2020.07.006

Sequence Information:

  • Length: 1154
  • Mass: 133277
  • Checksum: A2C4BE27851ACABB
  • Sequence:
    • MQYLNIKEDC NAMAFCAKMR SSKKTEVNLE APEPGVEVIF YLSDREPLRL GSGEYTAEEL 
CIRAAQACRI SPLCHNLFAL YDENTKLWYA PNRTITVDDK MSLRLHYRMR FYFTNWHGTN 
DNEQSVWRHS PKKQKNGYEK KKIPDATPLL DASSLEYLFA QGQYDLVKCL APIRDPKTEQ 
DGHDIENECL GMAVLAISHY AMMKKMQLPE LPKDISYKRY IPETLNKSIR QRNLLTRMRI 
NNVFKDFLKE FNNKTICDSS VSTHDLKVKY LATLETLTKH YGAEIFETSM LLISSENEMN 
WFHSNDGGNV LYYEVMVTGN LGIQWRHKPN VVSVEKEKNK LKRKKLENKH KKDEEKNKIR 
EEWNNFSYFP EITHIVIKES VVSINKQDNK KMELKLSSHE EALSFVSLVD GYFRLTADAH 
HYLCTDVAPP LIVHNIQNGC HGPICTEYAI NKLRQEGSEE GMYVLRWSCT DFDNILMTVT 
CFEKSEQVQG AQKQFKNFQI EVQKGRYSLH GSDRSFPSLG DLMSHLKKQI LRTDNISFML 
KRCCQPKPRE ISNLLVATKK AQEWQPVYPM SQLSFDRILK KDLVQGEHLG RGTRTHIYSG 
TLMDYKDDEG TSEEKKIKVI LKVLDPSHRD ISLAFFEAAS MMRQVSHKHI VYLYGVCVRD 
VENIMVEEFV EGGPLDLFMH RKSDVLTTPW KFKVAKQLAS ALSYLEDKDL VHGNVCTKNL 
LLAREGIDSE CGPFIKLSDP GIPITVLSRQ ECIERIPWIA PECVEDSKNL SVAADKWSFG 
TTLWEICYNG EIPLKDKTLI EKERFYESRC RPVTPSCKEL ADLMTRCMNY DPNQRPFFRA 
IMRDINKLEE QNPDIVSEKK PATEVDPTHF EKRFLKRIRD LGEGHFGKVE LCRYDPEGDN 
TGEQVAVKSL KPESGGNHIA DLKKEIEILR NLYHENIVKY KGICTEDGGN GIKLIMEFLP 
SGSLKEYLPK NKNKINLKQQ LKYAVQICKG MDYLGSRQYV HRDLAARNVL VESEHQVKIG 
DFGLTKAIET DKEYYTVKDD RDSPVFWYAP ECLMQSKFYI ASDVWSFGVT LHELLTYCDS 
DSSPMALFLK MIGPTHGQMT VTRLVNTLKE GKRLPCPPNC PDEVYQLMRK CWEFQPSNRT 
SFQNLIEGFE ALLK

Genular Protein ID: 2093571797

Symbol: Q6P669_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6P669

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 351
  • Mass: 40931
  • Checksum: 9763318A8CBF7B3E
  • Sequence:
    • MQYLNIKEDC NAMAFCAKMR SSKKTEVNLE APEPGVEVIF YLSDREPLRL GSGEYTAEEL 
CIRAAQACRI SPLCHNLFAL YDENTKLWYA PNRTITVDDK MSLRLHYRMR FYFTNWHGTN 
DNEQSVWRHS PKKQKNGYEK KKIPDATPLL DASSLEYLFA QGQYDLVKCL APIRDPKTEQ 
DGHDIENECL GMAVLAISHY AMMKKMQLPE LPKDISYKRY IPETLNKSIR QRNLLTRMRI 
NNVFKDFLKE FNNKTICDSS VSTHDLKVKY LATLETLTKH YGAEIFETSM LLISSENEMN 
WFHSNDGGNV LYYEVMVTGN LGIQWRHKPN VVSVEKEKNK LKKKKKKKKK K

Genular Protein ID: 2730941922

Symbol: A0A8V8TPQ9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8V8TPQ9

Database IDs:

ARBA 8 CDD 4 CTD 1 ChEBI 7 EC 1 EMBL 7 EPD 1 Ensembl 3 GO 11 Gene3D 2 GeneTree 1 HGNC 1 InterPro 17 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 3 PROSITE 8 PROSITE-ProRule 2 Pfam 4 Proteomes 2 RefSeq 2 Rhea 3 RuleBase 1 SMART 3 SUPFAM 4

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 1153
  • Mass: 133149
  • Checksum: 05C2FB9813191268
  • Sequence:
    • MQYLNIKEDC NAMAFCAKMR SSKKTEVNLE APEPGVEVIF YLSDREPLRL GSGEYTAEEL 
CIRAAQACRI SPLCHNLFAL YDENTKLWYA PNRTITVDDK MSLRLHYRMR FYFTNWHGTN 
DNEQSVWRHS PKKQKNGYEK KKIPDATPLL DASSLEYLFA QGQYDLVKCL APIRDPKTEQ 
DGHDIENECL GMAVLAISHY AMMKKMQLPE LPKDISYKRY IPETLNKSIR QRNLLTRMRI 
NNVFKDFLKE FNNKTICDSS VSTHDLKVKY LATLETLTKH YGAEIFETSM LLISSENEMN 
WFHSNDGGNV LYYEVMVTGN LGIQWRHKPN VVSVEKEKNK LKRKKLENKH KKDEEKNKIR 
EEWNNFSYFP EITHIVIKES VVSINKQDNK KMELKLSSHE EALSFVSLVD GYFRLTADAH 
HYLCTDVAPP LIVHNIQNGC HGPICTEYAI NKLRQEGSEE GMYVLRWSCT DFDNILMTVT 
CFEKSEVQGA QKQFKNFQIE VQKGRYSLHG SDRSFPSLGD LMSHLKKQIL RTDNISFMLK 
RCCQPKPREI SNLLVATKKA QEWQPVYPMS QLSFDRILKK DLVQGEHLGR GTRTHIYSGT 
LMDYKDDEGT SEEKKIKVIL KVLDPSHRDI SLAFFEAASM MRQVSHKHIV YLYGVCVRDV 
ENIMVEEFVE GGPLDLFMHR KSDVLTTPWK FKVAKQLASA LSYLEDKDLV HGNVCTKNLL 
LAREGIDSEC GPFIKLSDPG IPITVLSRQE CIERIPWIAP ECVEDSKNLS VAADKWSFGT 
TLWEICYNGE IPLKDKTLIE KERFYESRCR PVTPSCKELA DLMTRCMNYD PNQRPFFRAI 
MRDINKLEEQ NPDIVSEKKP ATEVDPTHFE KRFLKRIRDL GEGHFGKVEL CRYDPEGDNT 
GEQVAVKSLK PESGGNHIAD LKKEIEILRN LYHENIVKYK GICTEDGGNG IKLIMEFLPS 
GSLKEYLPKN KNKINLKQQL KYAVQICKGM DYLGSRQYVH RDLAARNVLV ESEHQVKIGD 
FGLTKAIETD KEYYTVKDDR DSPVFWYAPE CLMQSKFYIA SDVWSFGVTL HELLTYCDSD 
SSPMALFLKM IGPTHGQMTV TRLVNTLKEG KRLPCPPNCP DEVYQLMRKC WEFQPSNRTS 
FQNLIEGFEA LLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.