Details for: P4HA1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 358.2238
Cell Significance Index: -55.7200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 212.8579
Cell Significance Index: -53.9900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 147.5794
Cell Significance Index: -60.8000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 124.1415
Cell Significance Index: -58.6100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 115.6410
Cell Significance Index: -46.9800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 107.6819
Cell Significance Index: -55.3900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 87.5083
Cell Significance Index: -58.7200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 49.3641
Cell Significance Index: -47.1300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 45.5653
Cell Significance Index: -56.1800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 21.1601
Cell Significance Index: -56.6900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.3181
Cell Significance Index: -56.5000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 13.3282
Cell Significance Index: -29.1700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 5.3825
Cell Significance Index: 131.3300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.2064
Cell Significance Index: 82.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.5476
Cell Significance Index: 195.5000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.3359
Cell Significance Index: 463.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.5046
Cell Significance Index: 301.8200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4216
Cell Significance Index: 776.3600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.2835
Cell Significance Index: 21.6200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1443
Cell Significance Index: 64.2100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.0988
Cell Significance Index: 29.3400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0497
Cell Significance Index: 54.5300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.9034
Cell Significance Index: 1701.0400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.8998
Cell Significance Index: 1385.1800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.8949
Cell Significance Index: 122.8900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.8742
Cell Significance Index: 313.5700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.7161
Cell Significance Index: 973.6300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.6548
Cell Significance Index: 17.5500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6508
Cell Significance Index: 450.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5720
Cell Significance Index: 56.5800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5178
Cell Significance Index: 63.6700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.5147
Cell Significance Index: 233.5900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5088
Cell Significance Index: 82.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4903
Cell Significance Index: 53.3300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.4640
Cell Significance Index: 855.7400 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.4152
Cell Significance Index: 2.5800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3568
Cell Significance Index: 64.3200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3172
Cell Significance Index: 286.4200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2995
Cell Significance Index: 38.3900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2871
Cell Significance Index: 182.3100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2466
Cell Significance Index: 3.6400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1982
Cell Significance Index: 37.7200 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1942
Cell Significance Index: 3.7900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1362
Cell Significance Index: 2.9500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1092
Cell Significance Index: 7.3400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.1008
Cell Significance Index: 1.4500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0782
Cell Significance Index: 34.5800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0743
Cell Significance Index: 3.3700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0677
Cell Significance Index: 2.3800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0329
Cell Significance Index: 2.0200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0172
Cell Significance Index: 0.3600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0128
Cell Significance Index: 2.1800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0041
Cell Significance Index: -0.4300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0301
Cell Significance Index: -22.3300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0304
Cell Significance Index: -23.0500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0428
Cell Significance Index: -26.7100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0476
Cell Significance Index: -0.5900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0502
Cell Significance Index: -36.8400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0745
Cell Significance Index: -42.0400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1111
Cell Significance Index: -11.3500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1548
Cell Significance Index: -2.5900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1623
Cell Significance Index: -46.7100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1705
Cell Significance Index: -1.0300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1733
Cell Significance Index: -25.1900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1898
Cell Significance Index: -22.3800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2023
Cell Significance Index: -8.9500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2076
Cell Significance Index: -43.7200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2168
Cell Significance Index: -5.9000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2517
Cell Significance Index: -13.1100 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.2639
Cell Significance Index: -3.3800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.2836
Cell Significance Index: -19.6100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2857
Cell Significance Index: -10.8200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3122
Cell Significance Index: -23.2700 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.3135
Cell Significance Index: -4.7700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3166
Cell Significance Index: -36.9000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3270
Cell Significance Index: -15.2500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3373
Cell Significance Index: -7.2100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3435
Cell Significance Index: -39.2100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3523
Cell Significance Index: -22.7300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3563
Cell Significance Index: -46.0400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3767
Cell Significance Index: -17.7100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3886
Cell Significance Index: -44.5200 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.3963
Cell Significance Index: -5.8500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4353
Cell Significance Index: -22.8600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4900
Cell Significance Index: -14.0500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.5052
Cell Significance Index: -35.7300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.5377
Cell Significance Index: -14.1400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5398
Cell Significance Index: -9.2500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.5466
Cell Significance Index: -34.4500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.5936
Cell Significance Index: -16.9400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6232
Cell Significance Index: -31.4900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6468
Cell Significance Index: -51.2300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.6516
Cell Significance Index: -18.2100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6786
Cell Significance Index: -41.6100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.6965
Cell Significance Index: -15.2500 - Cell Name: peg cell (CL4033014)
Fold Change: -0.7318
Cell Significance Index: -16.9100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7560
Cell Significance Index: -26.2700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.8045
Cell Significance Index: -23.1800 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.8253
Cell Significance Index: -11.5400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.8780
Cell Significance Index: -8.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1362491801
Symbol: P4HA1_HUMAN
Name: Prolyl 4-hydroxylase subunit alpha-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2543975
Title: Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.
PubMed ID: 2543975
PubMed ID: 7961714
Title: Structure and expression of the human gene for the alpha subunit of prolyl 4-hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.
PubMed ID: 7961714
PubMed ID: 15028279
Title: PCR isolation and cloning of novel splice variant mRNAs from known drug target genes.
PubMed ID: 15028279
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9211872
Title: Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
PubMed ID: 9211872
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 15456751
Title: The peptide-substrate-binding domain of collagen prolyl 4-hydroxylases is a tetratricopeptide repeat domain with functional aromatic residues.
PubMed ID: 15456751
Sequence Information:
- Length: 534
- Mass: 61049
- Checksum: EBAFA8CCF09A1DDB
- Sequence:
MIWYILIIGI LLPQSLAHPG FFTSIGQMTD LIHTEKDLVT SLKDYIKAEE DKLEQIKKWA EKLDRLTSTA TKDPEGFVGH PVNAFKLMKR LNTEWSELEN LVLKDMSDGF ISNLTIQRQY FPNDEDQVGA AKALLRLQDT YNLDTDTISK GNLPGVKHKS FLTAEDCFEL GKVAYTEADY YHTELWMEQA LRQLDEGEIS TIDKVSVLDY LSYAVYQQGD LDKALLLTKK LLELDPEHQR ANGNLKYFEY IMAKEKDVNK SASDDQSDQK TTPKKKGVAV DYLPERQKYE MLCRGEGIKM TPRRQKKLFC RYHDGNRNPK FILAPAKQED EWDKPRIIRF HDIISDAEIE IVKDLAKPRL RRATISNPIT GDLETVHYRI SKSAWLSGYE NPVVSRINMR IQDLTGLDVS TAEELQVANY GVGGQYEPHF DFARKDEPDA FKELGTGNRI ATWLFYMSDV SAGGATVFPE VGASVWPKKG TAVFWYNLFA SGEGDYSTRH AACPVLVGNK WVSNKWLHER GQEFRRPCTL SELE
Genular Protein ID: 3935894727
Symbol: Q5VSQ6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
PubMed ID: 11181995
Sequence Information:
- Length: 534
- Mass: 60967
- Checksum: 5FE1B10A8AC5E792
- Sequence:
MIWYILIIGI LLPQSLAHPG FFTSIGQMTD LIHTEKDLVT SLKDYIKAEE DKLEQIKKWA EKLDRLTSTA TKDPEGFVGH PVNAFKLMKR LNTEWSELEN LVLKDMSDGF ISNLTIQRQY FPNDEDQVGA AKALLRLQDT YNLDTDTISK GNLPGVKHKS FLTAEDCFEL GKVAYTEADY YHTELWMEQA LRQLDEGEIS TIDKVSVLDY LSYAVYQQGD LDKALLLTKK LLELDPEHQR ANGNLKYFEY IMAKEKDVNK SASDDQSDQK TTPKKKGVAV DYLPERQKYE MLCRGEGIKM TPRRQKKLFC RYHDGNRNPK FILAPAKQED EWDKPRIIRF HDIISDAEIE IVKDLAKPRL SRATVHDPET GKLTTAQYRV SKSAWLSGYE NPVVSRINMR IQDLTGLDVS TAEELQVANY GVGGQYEPHF DFARKDEPDA FKELGTGNRI ATWLFYMSDV SAGGATVFPE VGASVWPKKG TAVFWYNLFA SGEGDYSTRH AACPVLVGNK WVSNKWLHER GQEFRRPCTL SELE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.