Details for: UBXN1

Gene ID: 51035

Symbol: UBXN1

Ensembl ID: ENSG00000162191

Description: UBX domain protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 398.2122
    Cell Significance Index: -61.9400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 218.4957
    Cell Significance Index: -55.4200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 213.8379
    Cell Significance Index: -88.0900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 175.2585
    Cell Significance Index: -71.2000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 162.1507
    Cell Significance Index: -76.5600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 151.5207
    Cell Significance Index: -77.9400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 114.5044
    Cell Significance Index: -76.8400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 75.8424
    Cell Significance Index: -72.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 60.0914
    Cell Significance Index: -74.0900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.1214
    Cell Significance Index: -79.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.1966
    Cell Significance Index: -55.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.5118
    Cell Significance Index: -38.8800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.9927
    Cell Significance Index: -21.8700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 3.1031
    Cell Significance Index: 54.8400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.9045
    Cell Significance Index: 187.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.8819
    Cell Significance Index: 135.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.7957
    Cell Significance Index: 383.9300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.6901
    Cell Significance Index: 79.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.5981
    Cell Significance Index: 74.4800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.4286
    Cell Significance Index: 27.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.3552
    Cell Significance Index: 61.9300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.1923
    Cell Significance Index: 258.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.1266
    Cell Significance Index: 274.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.0101
    Cell Significance Index: 142.1600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.9979
    Cell Significance Index: 104.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9228
    Cell Significance Index: 236.4300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.7928
    Cell Significance Index: 19.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7886
    Cell Significance Index: 322.4400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.7378
    Cell Significance Index: 36.3800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.7074
    Cell Significance Index: 127.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.6537
    Cell Significance Index: 903.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.6394
    Cell Significance Index: 724.8000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.5146
    Cell Significance Index: 52.6300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.4403
    Cell Significance Index: 11.5000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4086
    Cell Significance Index: 38.3400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.2788
    Cell Significance Index: 23.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.1483
    Cell Significance Index: 53.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0828
    Cell Significance Index: 56.8500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9722
    Cell Significance Index: 124.6300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.9337
    Cell Significance Index: 21.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7311
    Cell Significance Index: 15.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7280
    Cell Significance Index: 37.8200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.6372
    Cell Significance Index: 108.8000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6150
    Cell Significance Index: 117.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5200
    Cell Significance Index: 469.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4087
    Cell Significance Index: 40.4300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.3073
    Cell Significance Index: 8.2100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2063
    Cell Significance Index: 1.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1308
    Cell Significance Index: 5.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0708
    Cell Significance Index: 1.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0701
    Cell Significance Index: 14.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0679
    Cell Significance Index: 13.4800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0400
    Cell Significance Index: 0.6700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0304
    Cell Significance Index: 23.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0109
    Cell Significance Index: 7.9900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0038
    Cell Significance Index: 0.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0021
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0139
    Cell Significance Index: -10.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0192
    Cell Significance Index: -36.2000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0216
    Cell Significance Index: -0.7600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0305
    Cell Significance Index: -56.2700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0405
    Cell Significance Index: -62.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0573
    Cell Significance Index: -77.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0579
    Cell Significance Index: -36.1300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0644
    Cell Significance Index: -0.8300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0732
    Cell Significance Index: -41.3000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0849
    Cell Significance Index: -30.4700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0874
    Cell Significance Index: -55.4800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0961
    Cell Significance Index: -66.4500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1238
    Cell Significance Index: -3.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1504
    Cell Significance Index: -68.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1976
    Cell Significance Index: -23.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2155
    Cell Significance Index: -24.6900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2242
    Cell Significance Index: -64.5100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2425
    Cell Significance Index: -51.0700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3108
    Cell Significance Index: -7.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3473
    Cell Significance Index: -21.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3898
    Cell Significance Index: -23.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4467
    Cell Significance Index: -64.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4526
    Cell Significance Index: -9.6400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5011
    Cell Significance Index: -57.2000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5614
    Cell Significance Index: -17.9800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6568
    Cell Significance Index: -52.0200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.6944
    Cell Significance Index: -11.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7490
    Cell Significance Index: -77.9900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.7800
    Cell Significance Index: -4.8000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.9810
    Cell Significance Index: -75.2800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.0097
    Cell Significance Index: -67.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.0312
    Cell Significance Index: -14.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.0712
    Cell Significance Index: -60.1100
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -1.2045
    Cell Significance Index: -7.5400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2576
    Cell Significance Index: -77.1100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.4075
    Cell Significance Index: -21.0900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.4151
    Cell Significance Index: -8.5500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -1.4250
    Cell Significance Index: -11.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.4854
    Cell Significance Index: -43.7500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.6122
    Cell Significance Index: -71.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.6199
    Cell Significance Index: -41.6400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.6899
    Cell Significance Index: -28.9600
  • Cell Name: germ cell (CL0000586)
    Fold Change: -1.8085
    Cell Significance Index: -13.6600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** UBXN1 is a gene with a relatively short coding sequence, spanning approximately 4,500 nucleotides. Its expression is widespread across various cell types, including hematopoietic oligopotent progenitor cells, embryonic stem cells, and smooth muscle fibers. The protein product of UBXN1, UBXN1_HUMAN, is a ubiquitin-binding protein with a UBX domain, which is characterized by its ability to interact with ubiquitin and other proteins. This domain is crucial for the protein's function in various cellular processes. **Pathways and Functions** UBXN1 is implicated in multiple cellular pathways, including: 1. **DNA double-strand break repair**: UBXN1 plays a crucial role in the recruitment and activation of repair proteins at DNA double-strand breaks, ensuring the integrity of the genome. 2. **Protein degradation**: UBXN1 is involved in the regulation of protein degradation through its interaction with ubiquitin-binding proteins, such as UBE2M. 3. **N-glycan trimming**: UBXN1 participates in the regulation of N-glycan trimming in the endoplasmic reticulum, which is essential for protein quality control. 4. **Metabolism of proteins**: UBXN1 is involved in the regulation of protein metabolism, including protein degradation and synthesis. **Clinical Significance** UBXN1 has been implicated in various diseases, including: 1. **Cancer**: UBXN1 has been associated with cancer development and progression, particularly in hematological malignancies. 2. **Neurodegenerative diseases**: UBXN1 has been linked to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Immunological disorders**: UBXN1 has been implicated in immunological disorders, including autoimmune diseases and immunodeficiency syndromes. In conclusion, UBXN1 is a multifaceted gene with a wide range of cellular functions. Its involvement in DNA double-strand break repair, protein degradation, and N-glycan trimming highlights its importance in maintaining cellular homeostasis. The clinical significance of UBXN1 in various diseases underscores the need for further research into its role in human health and disease. As an expert immunologist, I believe that a deeper understanding of UBXN1's functions and implications will provide valuable insights into the development of novel therapeutic strategies for various diseases.

Genular Protein ID: 1586459026

Symbol: UBXN1_HUMAN

Name: UBX domain-containing protein 1

UniProtKB Accession Codes:

Q04323 Q9BV93 Q9BVV5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15362974

Title: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.

PubMed ID: 15362974

DOI: 10.1042/bj20041498

PubMed ID: 18775313

Title: UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

PubMed ID: 18775313

DOI: 10.1016/j.cell.2008.06.048

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20351172

Title: The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

PubMed ID: 20351172

DOI: 10.1128/mcb.01056-09

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23545497

Title: UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.

PubMed ID: 23545497

DOI: 10.1016/j.celrep.2013.02.027

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25681446

Title: Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor kappaB (NF-kappaB) signaling.

PubMed ID: 25681446

DOI: 10.1074/jbc.m114.631689

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28152074

Title: Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFkappaBeta signaling by stabilizing IkappaBalpha.

PubMed ID: 28152074

DOI: 10.1371/journal.ppat.1006187

PubMed ID: 29769705

Title: Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1.

PubMed ID: 29769705

DOI: 10.1038/s41598-018-25815-9

Sequence Information:

  • Length: 297
  • Mass: 33325
  • Checksum: E4E0C8BBAC93F2BB
  • Sequence:
    • MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHIL 
GREPTSSEQG GLEGSGSAAG EGKPALSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 
ERQRRRQGQE LSAARQRLQE DEMRRAAEER RREKAEELAA RQRVREKIER DKAERAKKYG 
GSVGSQPPPV APEPGPVPSS PSQEPPTKRE YDQCRIQVRL PDGTSLTQTF RAREQLAAVR 
LYVELHRGEE LGGGQDPVQL LSGFPRRAFS EADMERPLQE LGLVPSAVLI VAKKCPS

Genular Protein ID: 4220902295

Symbol: A0A087WTZ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WTZ5

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 238
  • Mass: 27016
  • Checksum: 11C6FC2E14E4F85A
  • Sequence:
    • MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWML ELVAQKQRER EEREEREALE 
RERQRRRQGQ ELSAARQRLQ EDEMRRAAEE RRREKAEELA ARQRVREKIE RDKAERAKKY 
GGSVGSQPPP VAPEPGPVPS SPSQEPPTKR EYDQCRIQVR LPDGTSLTQT FRAREQLAAV 
RLYVELHRGE ELGGGQDPVQ LLSGFPRRAF SEADMERPLQ ELGLVPSAVL IVAKKCPS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.