Details for: PTMA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 1671.1538
Cell Significance Index: -259.9400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 1046.6270
Cell Significance Index: -265.4700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 848.6395
Cell Significance Index: -349.6000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 722.3758
Cell Significance Index: -341.0500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 665.3379
Cell Significance Index: -342.2400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 510.8028
Cell Significance Index: -342.7600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 256.8786
Cell Significance Index: -316.7200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 87.1454
Cell Significance Index: -343.8800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 77.4112
Cell Significance Index: -237.7700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 49.8266
Cell Significance Index: -109.0500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 46.5067
Cell Significance Index: -124.5900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 14.9374
Cell Significance Index: 519.0700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 13.4604
Cell Significance Index: 353.9400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 11.2904
Cell Significance Index: 530.6400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 11.0501
Cell Significance Index: 580.1700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 10.1017
Cell Significance Index: 114.7600 - Cell Name: theca cell (CL0000503)
Fold Change: 9.7029
Cell Significance Index: 57.0100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 9.3720
Cell Significance Index: 165.6200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 8.5766
Cell Significance Index: 553.3200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 8.3753
Cell Significance Index: 987.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 8.3266
Cell Significance Index: 1143.4700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.9846
Cell Significance Index: 3530.1900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 7.9591
Cell Significance Index: 4346.6500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 7.7232
Cell Significance Index: 161.6600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 7.2487
Cell Significance Index: 512.6600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 7.1754
Cell Significance Index: 882.2900 - Cell Name: peg cell (CL4033014)
Fold Change: 7.1613
Cell Significance Index: 165.4500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 7.0000
Cell Significance Index: 200.6600 - Cell Name: lactocyte (CL0002325)
Fold Change: 6.9266
Cell Significance Index: 894.8700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 6.7133
Cell Significance Index: 500.3400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 6.5506
Cell Significance Index: 1180.8600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 6.5034
Cell Significance Index: 120.2000 - Cell Name: odontoblast (CL0000060)
Fold Change: 5.5594
Cell Significance Index: 712.6800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 5.2584
Cell Significance Index: 143.1300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 5.1769
Cell Significance Index: 56.2800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 4.0147
Cell Significance Index: 51.4200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 3.6078
Cell Significance Index: 356.8900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 3.3206
Cell Significance Index: 2513.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 2.9700
Cell Significance Index: 507.1500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.9176
Cell Significance Index: 136.0300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.6967
Cell Significance Index: 79.2000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1125
Cell Significance Index: 419.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.0501
Cell Significance Index: 589.8700 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 2.0011
Cell Significance Index: 12.3200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.5295
Cell Significance Index: 40.8400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.3360
Cell Significance Index: 82.1200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 1.2921
Cell Significance Index: 947.3800 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.9575
Cell Significance Index: 7.6500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.8244
Cell Significance Index: 46.2600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4550
Cell Significance Index: 91.2700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4110
Cell Significance Index: 66.8400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3766
Cell Significance Index: 71.6600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2538
Cell Significance Index: 91.0400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.1464
Cell Significance Index: 2.4500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0139
Cell Significance Index: -26.1100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1087
Cell Significance Index: -11.1000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1321
Cell Significance Index: -203.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1481
Cell Significance Index: -201.4000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1483
Cell Significance Index: -273.4200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1562
Cell Significance Index: -115.6900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2217
Cell Significance Index: -17.5600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.3052
Cell Significance Index: -190.5700 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -0.3619
Cell Significance Index: -3.1100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.3902
Cell Significance Index: -247.8100 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -0.4017
Cell Significance Index: -2.8800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.4312
Cell Significance Index: -243.1800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4322
Cell Significance Index: -49.3300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.6089
Cell Significance Index: -276.3500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.6960
Cell Significance Index: -36.1600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.7652
Cell Significance Index: -161.1700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.1486
Cell Significance Index: -32.1000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.5356
Cell Significance Index: -39.2300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -1.6267
Cell Significance Index: -14.9800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.8218
Cell Significance Index: -264.8300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.9057
Cell Significance Index: -120.1100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -1.9545
Cell Significance Index: -227.7700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.9801
Cell Significance Index: -226.8500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -2.6473
Cell Significance Index: -84.7900 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -2.8917
Cell Significance Index: -49.8500 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -2.9743
Cell Significance Index: -17.9700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -3.1024
Cell Significance Index: -140.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -3.1919
Cell Significance Index: -332.3500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -3.5993
Cell Significance Index: -276.2100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -3.8835
Cell Significance Index: -261.1300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -3.9610
Cell Significance Index: -67.8800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -4.9818
Cell Significance Index: -67.9700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -5.5365
Cell Significance Index: -339.4400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -5.8873
Cell Significance Index: -70.1800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -6.0818
Cell Significance Index: -131.7600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -6.0876
Cell Significance Index: -317.1000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -6.1012
Cell Significance Index: -91.4200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -6.2799
Cell Significance Index: -184.9700 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -6.7394
Cell Significance Index: -56.6100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -6.8444
Cell Significance Index: -302.7500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -6.8506
Cell Significance Index: -183.2500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -7.1996
Cell Significance Index: -172.6700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -7.6048
Cell Significance Index: -190.1000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -8.1573
Cell Significance Index: -299.4500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -8.2562
Cell Significance Index: -312.6400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -8.3232
Cell Significance Index: -213.9500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4066477721
Symbol: PTMA_HUMAN
Name: Prothymosin alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3467312
Title: The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA.
PubMed ID: 3467312
PubMed ID: 3466166
Title: Molecular cloning of cDNA for human prothymosin alpha.
PubMed ID: 3466166
PubMed ID: 2708378
Title: Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products.
PubMed ID: 2708378
PubMed ID: 2785990
Title: The expression of prothymosin alpha gene in T lymphocytes and leukemic lymphoid cells is tied to lymphocyte proliferation.
PubMed ID: 2785990
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7916742
Title: Prothymosin alpha gene in humans: organization of its promoter region and localization to chromosome 2.
PubMed ID: 7916742
DOI: 10.1007/bf00202480
PubMed ID: 3532956
Title: Human prothymosin alpha: amino acid sequence and immunologic properties.
PubMed ID: 3532956
PubMed ID: 8485135
Title: Phosphorylation of human and bovine prothymosin alpha in vivo.
PubMed ID: 8485135
DOI: 10.1021/bi00068a015
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16478804
Title: Regulation of apoptosis by the p8/prothymosin alpha complex.
PubMed ID: 16478804
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 22115779
Sequence Information:
- Length: 111
- Mass: 12203
- Checksum: 910BBF9D8D14B8E7
- Sequence:
MSDAAVDTSS EITTKDLKEK KEVVEEAENG RDAPANGNAE NEENGEQEAD NEVDEEEEEG GEEEEEEEEG DGEEEDGDED EEAESATGKR AAEDDEDDDV DTKKQKTDED D
Genular Protein ID: 86522470
Symbol: Q53S24_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 110
- Mass: 12074
- Checksum: 3A76436E79930993
- Sequence:
MSDAAVDTSS EITTKDLKEK KEVVEEAENG RDAPANGNAN EENGEQEADN EVDEEEEEGG EEEEEEEEGD GEEEDGDEDE EAESATGKRA AEDDEDDDVD TKKQKTDEDD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.