Details for: RPL5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: embryonic stem cell (CL0002322)
Fold Change: 651.6363
Cell Significance Index: -268.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 589.9158
Cell Significance Index: -239.6600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 541.7448
Cell Significance Index: -255.7700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 520.0382
Cell Significance Index: -267.5000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 383.2064
Cell Significance Index: -257.1400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 256.1056
Cell Significance Index: -244.5200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 38.8486
Cell Significance Index: -104.0700 - Cell Name: pro-T cell (CL0000827)
Fold Change: 17.3881
Cell Significance Index: 444.2100 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 15.8386
Cell Significance Index: 202.8400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 13.6914
Cell Significance Index: 475.7700 - Cell Name: abnormal cell (CL0001061)
Fold Change: 13.4566
Cell Significance Index: 1374.5900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 11.8787
Cell Significance Index: 558.2900 - Cell Name: theca cell (CL0000503)
Fold Change: 11.4876
Cell Significance Index: 67.4900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 10.8691
Cell Significance Index: 311.5700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 10.3891
Cell Significance Index: 273.1800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 9.3328
Cell Significance Index: 195.3500 - Cell Name: peg cell (CL4033014)
Fold Change: 9.1510
Cell Significance Index: 211.4200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 9.0129
Cell Significance Index: 1237.7200 - Cell Name: lactocyte (CL0002325)
Fold Change: 8.9605
Cell Significance Index: 1157.6400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 8.6578
Cell Significance Index: 1064.5500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 8.6445
Cell Significance Index: 152.7600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 8.5997
Cell Significance Index: 93.4900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 8.5981
Cell Significance Index: 608.1000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 8.3694
Cell Significance Index: 95.0800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 8.2365
Cell Significance Index: 1484.7800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.5358
Cell Significance Index: 3331.7600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 7.4224
Cell Significance Index: 4053.5300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 7.2636
Cell Significance Index: 541.3500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 7.0589
Cell Significance Index: 832.4600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 6.9105
Cell Significance Index: 445.8300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.9728
Cell Significance Index: 278.4800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 5.8782
Cell Significance Index: 160.0000 - Cell Name: odontoblast (CL0000060)
Fold Change: 5.4408
Cell Significance Index: 697.4800 - Cell Name: kidney cell (CL1000497)
Fold Change: 5.3944
Cell Significance Index: 43.0700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 5.0730
Cell Significance Index: 866.2400 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 4.1143
Cell Significance Index: 25.3200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 4.0839
Cell Significance Index: 119.9400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 3.8635
Cell Significance Index: 35.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 3.8044
Cell Significance Index: 198.1700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.2027
Cell Significance Index: 168.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.0594
Cell Significance Index: 607.1500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.5437
Cell Significance Index: 67.9200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 2.1045
Cell Significance Index: 1592.9400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.4516
Cell Significance Index: 26.8300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4327
Cell Significance Index: 1293.6200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 1.1430
Cell Significance Index: 838.0400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8821
Cell Significance Index: 176.9500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.7972
Cell Significance Index: 63.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3942
Cell Significance Index: 75.0200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.3201
Cell Significance Index: 36.5400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2752
Cell Significance Index: 15.4400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2138
Cell Significance Index: 9.6900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2050
Cell Significance Index: 10.6500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1251
Cell Significance Index: 44.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0982
Cell Significance Index: 9.7100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0471
Cell Significance Index: 88.7100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0643
Cell Significance Index: -118.5000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0891
Cell Significance Index: -137.1300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0952
Cell Significance Index: -70.4900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1792
Cell Significance Index: -243.6800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2068
Cell Significance Index: -12.7100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2119
Cell Significance Index: -119.5000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.2148
Cell Significance Index: -134.1300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.2904
Cell Significance Index: -184.4400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.4241
Cell Significance Index: -192.4900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.4250
Cell Significance Index: -69.1200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.5008
Cell Significance Index: -105.4800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.8112
Cell Significance Index: -233.4100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.9769
Cell Significance Index: -111.9200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.4675
Cell Significance Index: -24.5600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.4835
Cell Significance Index: -215.6500 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.6962
Cell Significance Index: -29.2400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.7263
Cell Significance Index: -55.2900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.9357
Cell Significance Index: -11.7000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -2.0606
Cell Significance Index: -129.8700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -2.0735
Cell Significance Index: -72.8600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.2978
Cell Significance Index: -239.2600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -2.6394
Cell Significance Index: -202.5400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -2.7148
Cell Significance Index: -187.7400 - Cell Name: perivascular cell (CL4033054)
Fold Change: -3.0126
Cell Significance Index: -13.9100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -3.1938
Cell Significance Index: -214.7500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -3.7294
Cell Significance Index: -228.6500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -3.8583
Cell Significance Index: -83.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -4.0569
Cell Significance Index: -108.5200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -4.0678
Cell Significance Index: -55.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -4.6548
Cell Significance Index: -79.7700 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -5.0010
Cell Significance Index: -104.3000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -5.0387
Cell Significance Index: -75.5000 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -5.0611
Cell Significance Index: -43.4900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -5.1505
Cell Significance Index: -138.0100 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -5.3018
Cell Significance Index: -28.9100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -5.3188
Cell Significance Index: -156.6600 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -5.3692
Cell Significance Index: -45.1000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -5.3960
Cell Significance Index: -81.3200 - Cell Name: germ cell (CL0000586)
Fold Change: -5.5498
Cell Significance Index: -41.9100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -5.5918
Cell Significance Index: -139.7800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -5.7024
Cell Significance Index: -252.2300 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -6.2848
Cell Significance Index: -80.9400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -6.3910
Cell Significance Index: -234.6100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -6.8204
Cell Significance Index: -223.3000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3733615456
Symbol: RL5_HUMAN
Name: 60S ribosomal protein L5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7772601
Title: Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.
PubMed ID: 7772601
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12962325
Title: Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing.
PubMed ID: 12962325
PubMed ID: 8806611
Title: Interaction of the beta subunit of casein kinase II with the ribosomal protein L5.
PubMed ID: 8806611
PubMed ID: 7937132
Title: U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals.
PubMed ID: 7937132
PubMed ID: 9687515
Title: Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells.
PubMed ID: 9687515
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 15469983
Title: NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence.
PubMed ID: 15469983
PubMed ID: 19061985
Title: Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients.
PubMed ID: 19061985
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20926688
Title: RRP1B targets PP1 to mammalian cell nucleoli and is associated with pre-60S ribosomal subunits.
PubMed ID: 20926688
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24120868
Title: The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress.
PubMed ID: 24120868
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24524803
Title: A new system for naming ribosomal proteins.
PubMed ID: 24524803
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 23636399
Title: Structures of the human and Drosophila 80S ribosome.
PubMed ID: 23636399
DOI: 10.1038/nature12104
PubMed ID: 32669547
Title: Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
PubMed ID: 32669547
PubMed ID: 19191325
Title: Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemia.
PubMed ID: 19191325
DOI: 10.1002/humu.20874
Sequence Information:
- Length: 297
- Mass: 34363
- Checksum: 07CA9FBA842BD2A3
- Sequence:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVKV GLTNYAAAYC TGLLLARRLL NRFGMDKIYE GQVEVTGDEY NVESIDGQPG AFTCYLDAGL ARTTTGNKVF GALKGAVDGG LSIPHSTKRF PGYDSESKEF NAEVHRKHIM GQNVADYMRY LMEEDEDAYK KQFSQYIKNS VTPDMMEEMY KKAHAAIREN PVYEKKPKKE VKKKRWNRPK MSLAQKKDRV AQKKASFLRA QERAAES
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.