RPS27 | ENSG00000177954 | NCBI 6232

Details for: RPS27

Gene ID: 6232

Symbol: RPS27

Ensembl ID: ENSG00000177954

Description: ribosomal protein S27

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-HSA-72662)
Amplification of signal from the kinetochores
(R-HSA-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-HSA-141444)
Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cell cycle checkpoints
(R-HSA-69620)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-HSA-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
Mitotic spindle checkpoint
(R-HSA-69618)
M phase
(R-HSA-68886)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Peptide chain elongation
(R-HSA-156902)
Regulation of expression of slits and robos
(R-HSA-9010553)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Ribosomal scanning and start codon recognition
(R-HSA-72702)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1 modulates host translation machinery
(R-HSA-9735869)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2 modulates host translation machinery
(R-HSA-9754678)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signaling by robo receptors
(R-HSA-376176)
Signal transduction
(R-HSA-162582)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Translation initiation complex formation
(R-HSA-72649)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic ribosome
(GO:0022626)
Cytosolic small ribosomal subunit
(GO:0022627)
Dna binding
(GO:0003677)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Ribosomal small subunit assembly
(GO:0000028)
Ribosomal small subunit biogenesis
(GO:0042274)
Ribosome
(GO:0005840)
Rna binding
(GO:0003723)
Rrna processing
(GO:0006364)
Small-subunit processome
(GO:0032040)
Structural constituent of ribosome
(GO:0003735)
Translation
(GO:0006412)
Zinc ion binding
(GO:0008270)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: embryonic stem cell (CL0002322)
Fold Change: 802.9176
Cell Significance Index: -330.7600
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 668.6186
Cell Significance Index: -315.6700
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 654.1595
Cell Significance Index: -336.4900
Cell Name: ileal goblet cell (CL1000326)
Fold Change: 472.6074
Cell Significance Index: -317.1300
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 33.4881
Cell Significance Index: -89.7100
Cell Name: hepatic pit cell (CL2000054)
Fold Change: 27.8157
Cell Significance Index: 74.5200
Cell Name: theca cell (CL0000503)
Fold Change: 23.8688
Cell Significance Index: 140.2300
Cell Name: abnormal cell (CL0001061)
Fold Change: 18.3137
Cell Significance Index: 1870.7400
Cell Name: pro-T cell (CL0000827)
Fold Change: 16.5186
Cell Significance Index: 422.0000
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 15.2615
Cell Significance Index: 437.4800
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 13.9447
Cell Significance Index: 655.3900
Cell Name: granulosa cell (CL0000501)
Fold Change: 13.7376
Cell Significance Index: 361.2300
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 13.1306
Cell Significance Index: 232.0400
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 11.7302
Cell Significance Index: 313.7800
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 11.2667
Cell Significance Index: 235.8300
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 11.2267
Cell Significance Index: 127.5400
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 10.7818
Cell Significance Index: 1325.7200
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 10.6598
Cell Significance Index: 1921.6300
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 10.5819
Cell Significance Index: 748.4000
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 10.1404
Cell Significance Index: 129.8700
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 9.8526
Cell Significance Index: 1353.0400
Cell Name: lactocyte (CL0002325)
Fold Change: 9.7838
Cell Significance Index: 1264.0000
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 9.5702
Cell Significance Index: 1128.6200
Cell Name: odontoblast (CL0000060)
Fold Change: 9.4162
Cell Significance Index: 1207.1000
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 9.3374
Cell Significance Index: 4128.3100
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 9.1812
Cell Significance Index: 684.2700
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 8.5237
Cell Significance Index: 157.5400
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 8.1100
Cell Significance Index: 6138.5900
Cell Name: cell in vitro (CL0001034)
Fold Change: 7.9123
Cell Significance Index: 4321.1100
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 6.4785
Cell Significance Index: 39.8700
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 6.4693
Cell Significance Index: 70.3300
Cell Name: early pro-B cell (CL0002046)
Fold Change: 6.4266
Cell Significance Index: 414.6100
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 6.3537
Cell Significance Index: 220.7900
Cell Name: peg cell (CL4033014)
Fold Change: 5.5148
Cell Significance Index: 127.4100
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 5.4592
Cell Significance Index: 160.3300
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 5.4257
Cell Significance Index: 284.8700
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 5.2827
Cell Significance Index: 143.7900
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 5.2250
Cell Significance Index: 48.1200
Cell Name: kidney cell (CL1000497)
Fold Change: 4.8733
Cell Significance Index: 38.9100
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.8341
Cell Significance Index: 225.3900
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 4.0912
Cell Significance Index: 698.5900
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 3.4856
Cell Significance Index: 157.9900
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 3.3148
Cell Significance Index: 2993.0200
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.6572
Cell Significance Index: 44.2500
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.4009
Cell Significance Index: 266.6000
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 1.2102
Cell Significance Index: 887.3200
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 1.0277
Cell Significance Index: 81.3900
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9700
Cell Significance Index: 192.5100
Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 0.8391
Cell Significance Index: 7.2100
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4764
Cell Significance Index: 77.4800
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1969
Cell Significance Index: 13.6200
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0491
Cell Significance Index: 4.8500
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0142
Cell Significance Index: -26.8300
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1175
Cell Significance Index: -216.7900
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1246
Cell Significance Index: -92.3200
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1448
Cell Significance Index: -222.9800
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.2308
Cell Significance Index: -313.7700
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.2528
Cell Significance Index: -90.6900
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2730
Cell Significance Index: -153.9900
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.2919
Cell Significance Index: -182.2700
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.3338
Cell Significance Index: -211.9800
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.3791
Cell Significance Index: -172.0800
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4433
Cell Significance Index: -27.2500
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5842
Cell Significance Index: -30.3500
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.6438
Cell Significance Index: -135.6100
Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.6534
Cell Significance Index: -74.5900
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.6766
Cell Significance Index: -19.5000
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.7584
Cell Significance Index: -38.3300
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.8376
Cell Significance Index: -168.0300
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.8724
Cell Significance Index: -251.0100
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.8957
Cell Significance Index: -15.4400
Cell Name: neuron associated cell (CL0000095)
Fold Change: -1.0023
Cell Significance Index: -41.0700
Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -1.0328
Cell Significance Index: -21.5400
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.3305
Cell Significance Index: -152.4300
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.5286
Cell Significance Index: -48.9600
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.8236
Cell Significance Index: -265.0800
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.8924
Cell Significance Index: -106.1900
Cell Name: mesenchymal cell (CL0008019)
Fold Change: -2.1206
Cell Significance Index: -35.4900
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -2.2851
Cell Significance Index: -57.1200
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -2.3496
Cell Significance Index: -148.0900
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.8811
Cell Significance Index: -300.0000
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -2.9462
Cell Significance Index: -103.5300
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -3.3194
Cell Significance Index: -18.1000
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -3.7591
Cell Significance Index: -288.4700
Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -3.9624
Cell Significance Index: -23.9400
Cell Name: paneth cell of colon (CL0009009)
Fold Change: -4.1564
Cell Significance Index: -62.2800
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -4.5001
Cell Significance Index: -275.9000
Cell Name: gut absorptive cell (CL0000677)
Fold Change: -4.5139
Cell Significance Index: -270.9900
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -4.7229
Cell Significance Index: -317.5700
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -4.7580
Cell Significance Index: -103.0800
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -4.8096
Cell Significance Index: -65.6200
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -6.5087
Cell Significance Index: -191.7100
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -6.9035
Cell Significance Index: -305.3600
Cell Name: perivascular cell (CL4033054)
Fold Change: -7.1970
Cell Significance Index: -33.2300
Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -7.5433
Cell Significance Index: -129.2700
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -7.5698
Cell Significance Index: -277.8800
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -8.1772
Cell Significance Index: -309.6500
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -8.6829
Cell Significance Index: -223.1900
Cell Name: Sertoli cell (CL0000216)
Fold Change: -9.0322
Cell Significance Index: -126.6900
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -9.0659
Cell Significance Index: -116.7500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics:** RPS27 is a 10-kDa protein that belongs to the ribosomal protein family. It is highly conserved across species, with high sequence similarity to its counterparts in other organisms. RPS27 is a critical component of the 40S ribosomal subunit, which is responsible for translating mRNA into proteins. The protein is also involved in the assembly of the 40S subunit and the formation of the 43S complex, a crucial step in translation initiation. **Pathways and Functions:** RPS27 is involved in various cellular processes, including: 1. **Ribosome biogenesis:** RPS27 plays a crucial role in the assembly of the 40S ribosomal subunit, which is essential for protein synthesis. 2. **Translation initiation:** RPS27 is involved in the formation of the 43S complex, a critical step in translation initiation. 3. **Cell cycle regulation:** RPS27 is involved in the regulation of the cell cycle, particularly during mitosis, where it plays a role in the separation of sister chromatids. 4. **Signal transduction:** RPS27 is involved in signal transduction pathways, including those mediated by Rho GTPases and Miro GTPases. 5. **Antigen presentation:** RPS27 is expressed on the surface of professional antigen-presenting cells, such as dendritic cells and macrophages. **Clinical Significance:** RPS27 has been implicated in various diseases, including: 1. **Influenza infection:** RPS27 has been shown to play a role in the replication of influenza virus, highlighting its importance in antiviral defense. 2. **Cancer:** RPS27 has been found to be overexpressed in various types of cancer, including breast, lung, and colon cancer. 3. **Neurological disorders:** RPS27 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it plays a role in protein aggregation and translation regulation. 4. **Infectious diseases:** RPS27 has been shown to be involved in the pathogenesis of infectious diseases, such as SARS-CoV-1 and SARS-CoV-2. **Conclusion:** RPS27 is a crucial protein that plays a vital role in ribosome biogenesis, translation, and cell cycle regulation. Its involvement in various cellular processes highlights its importance in maintaining cellular homeostasis and responding to environmental stresses. Further research is needed to fully understand the mechanisms by which RPS27 regulates cellular processes and to explore its potential as a therapeutic target in various diseases. **Future Directions:** 1. **Investigating RPS27's role in disease:** Further research is needed to explore RPS27's role in various diseases, including cancer, neurological disorders, and infectious diseases. 2. **Developing therapeutic strategies:** RPS27 could be a potential therapeutic target for diseases where its expression is dysregulated. 3. **Understanding RPS27's interactions with other proteins:** Further research is needed to understand RPS27's interactions with other proteins and how these interactions regulate cellular processes.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

40S ribosomal protein S27

Genular Protein ID: 4260677873

Symbol: RS27_HUMAN

Name: 40S ribosomal protein S27

UniProtKB Accession Codes:

P42677 Q5T4L6

Database IDs:

Citations:

PubMed ID: 8407955

Title: A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure.

PubMed ID: 8407955

DOI: 10.1016/s0021-9258(19)36910-8

PubMed ID: 8908372

Title: Primary structures and sequence analysis of human ribosomal proteins L39 and S27.

PubMed ID: 8908372

DOI: 10.1080/15216549600201203

PubMed ID: 11875025

Title: The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.

PubMed ID: 11875025

DOI: 10.1101/gr.214202

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 9582194

Title: A map of 75 human ribosomal protein genes.

PubMed ID: 9582194

DOI: 10.1101/gr.8.5.509

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25424902

Title: Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.

PubMed ID: 25424902

DOI: 10.1111/bjh.13229

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

Length: 84
Mass: 9461
Checksum: 242C4466AC8A8900
Sequence:

MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS 
TVLCQPTGGK ARLTEGCSFR RKQH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RPS27

Associated with

Cells (max top 100)

Other Information

A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. PubMed ID: 8407955

Primary structures and sequence analysis of human ribosomal proteins L39 and S27. PubMed ID: 8908372

The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. PubMed ID: 11875025

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. PubMed ID: 8706699

A map of 75 human ribosomal protein genes. PubMed ID: 9582194

Proteomic characterization of the human centrosome by protein correlation profiling. PubMed ID: 14654843

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

A new system for naming ribosomal proteins. PubMed ID: 24524803

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. PubMed ID: 25424902

Structures of the human and Drosophila 80S ribosome. PubMed ID: 23636399

Nucleolar maturation of the human small subunit processome. PubMed ID: 34516797