Details for: RO60
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 299.1413
Cell Significance Index: -46.5300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 201.7794
Cell Significance Index: -51.1800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 127.8270
Cell Significance Index: -60.3500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 119.3087
Cell Significance Index: -48.4700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 109.2761
Cell Significance Index: -56.2100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 90.6527
Cell Significance Index: -60.8300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 51.0818
Cell Significance Index: -48.7700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 45.5410
Cell Significance Index: -56.1500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.8513
Cell Significance Index: -50.5000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.8959
Cell Significance Index: -58.7800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.6292
Cell Significance Index: -38.7900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 10.4040
Cell Significance Index: -22.7700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.8337
Cell Significance Index: 115.5700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.6078
Cell Significance Index: 55.8700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.3080
Cell Significance Index: 259.5800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2496
Cell Significance Index: 250.6700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.2360
Cell Significance Index: 169.7400 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.1739
Cell Significance Index: 150.4900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.1647
Cell Significance Index: 60.6700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9914
Cell Significance Index: 26.9900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8665
Cell Significance Index: 106.5400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.8119
Cell Significance Index: 48.7400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.7978
Cell Significance Index: 49.0400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7654
Cell Significance Index: 42.9500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7382
Cell Significance Index: 264.7800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6954
Cell Significance Index: 125.3500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.6335
Cell Significance Index: 13.2600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.6070
Cell Significance Index: 31.8700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.5764
Cell Significance Index: 67.9800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5558
Cell Significance Index: 245.7200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.4560
Cell Significance Index: 5.1800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4460
Cell Significance Index: 28.7800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4101
Cell Significance Index: 223.9800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3699
Cell Significance Index: 70.3900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3328
Cell Significance Index: 36.2000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3092
Cell Significance Index: 279.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.2406
Cell Significance Index: 31.0800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2360
Cell Significance Index: 163.2100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2220
Cell Significance Index: 15.7000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2143
Cell Significance Index: 15.9700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.1455
Cell Significance Index: 7.3500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1443
Cell Significance Index: 11.0700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1336
Cell Significance Index: 3.8500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0890
Cell Significance Index: 4.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0693
Cell Significance Index: 4.7900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0605
Cell Significance Index: 113.9500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0563
Cell Significance Index: 1.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0452
Cell Significance Index: 28.7200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0223
Cell Significance Index: 10.1300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0072
Cell Significance Index: 11.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0060
Cell Significance Index: 0.5900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0053
Cell Significance Index: -3.9000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0054
Cell Significance Index: -10.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0155
Cell Significance Index: -21.1300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0212
Cell Significance Index: -0.4600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0316
Cell Significance Index: -1.1100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0388
Cell Significance Index: -6.3200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0466
Cell Significance Index: -35.2600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0573
Cell Significance Index: -1.5300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0574
Cell Significance Index: -42.5300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0580
Cell Significance Index: -0.9700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0700
Cell Significance Index: -1.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0720
Cell Significance Index: -12.2900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0813
Cell Significance Index: -3.8200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0902
Cell Significance Index: -50.8700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0952
Cell Significance Index: -9.7200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1077
Cell Significance Index: -3.0100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1242
Cell Significance Index: -77.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1346
Cell Significance Index: -15.4300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1400
Cell Significance Index: -7.2700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1515
Cell Significance Index: -22.0200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1581
Cell Significance Index: -45.4900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1743
Cell Significance Index: -5.0000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1795
Cell Significance Index: -2.1400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2018
Cell Significance Index: -4.8400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2103
Cell Significance Index: -14.1400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2248
Cell Significance Index: -10.1900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2982
Cell Significance Index: -62.8000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3127
Cell Significance Index: -13.8300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3393
Cell Significance Index: -5.0100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3613
Cell Significance Index: -42.1000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3617
Cell Significance Index: -7.9200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4099
Cell Significance Index: -8.0000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4389
Cell Significance Index: -16.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4986
Cell Significance Index: -51.9200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5323
Cell Significance Index: -17.0500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5518
Cell Significance Index: -43.7000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5632
Cell Significance Index: -16.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5909
Cell Significance Index: -14.7700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.5986
Cell Significance Index: -17.6300 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.6325
Cell Significance Index: -5.0500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.7115
Cell Significance Index: -18.2900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7291
Cell Significance Index: -44.7000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.7520
Cell Significance Index: -10.2600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7670
Cell Significance Index: -31.4300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7796
Cell Significance Index: -4.7100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.8361
Cell Significance Index: -9.0900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.8674
Cell Significance Index: -22.1600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8778
Cell Significance Index: -23.4800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.9003
Cell Significance Index: -11.5300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 363853676
Symbol: RO60_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3200833
Title: Molecular analysis of the 60-kDa human Ro ribonucleoprotein.
PubMed ID: 3200833
PubMed ID: 2649513
Title: Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen.
PubMed ID: 2649513
DOI: 10.1172/jci114013
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10545525
Title: Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies.
PubMed ID: 10545525
DOI: 10.1172/jci8003
PubMed ID: 10668799
Title: Interaction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteins.
PubMed ID: 10668799
PubMed ID: 18056422
Title: Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control.
PubMed ID: 18056422
DOI: 10.1101/gad.1603907
PubMed ID: 17289661
Title: Molecular composition of IMP1 ribonucleoprotein granules.
PubMed ID: 17289661
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 26382853
Title: The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression.
PubMed ID: 26382853
Sequence Information:
- Length: 538
- Mass: 60671
- Checksum: CD735B1DF2B13098
- Sequence:
MEESVNQMQP LNEKQIANSQ DGYVWQVTDM NRLHRFLCFG SEGGTYYIKE QKLGLENAEA LIRLIEDGRG CEVIQEIKSF SQEGRTTKQE PMLFALAICS QCSDISTKQA AFKAVSEVCR IPTHLFTFIQ FKKDLKESMK CGMWGRALRK AIADWYNEKG GMALALAVTK YKQRNGWSHK DLLRLSHLKP SSEGLAIVTK YITKGWKEVH ELYKEKALSV ETEKLLKYLE AVEKVKRTRD ELEVIHLIEE HRLVREHLLT NHLKSKEVWK ALLQEMPLTA LLRNLGKMTA NSVLEPGNSE VSLVCEKLCN EKLLKKARIH PFHILIALET YKTGHGLRGK LKWRPDEEIL KALDAAFYKT FKTVEPTGKR FLLAVDVSAS MNQRVLGSIL NASTVAAAMC MVVTRTEKDS YVVAFSDEMV PCPVTTDMTL QQVLMAMSQI PAGGTDCSLP MIWAQKTNTP ADVFIVFTDN ETFAGGVHPA IALREYRKKM DIPAKLIVCG MTSNGFTIAD PDDRGMLDMC GFDTGALDVI RNFTLDMI
Genular Protein ID: 3411088213
Symbol: G5E9R9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 263
- Mass: 28858
- Checksum: DA536816CB22FD62
- Sequence:
MPLTALLRNL GKMTANSVLE PGNSEVSLVC EKLCNEKLLK KARIHPFHIL IALETYKTGH GLRGKLKWRP DEEILKALDA AFYKTFKTVE PTGKRFLLAV DVSASMNQRV LGSILNASTV AAAMCMVVTR TEKDSYVVAF SDEMVPCPVT TDMTLQQVLM AMSQIPAGGT DCSLPMIWAQ KTNTPADVFI VFTDNETFAG GVHPAIALRE YRKKMDIPAK LIVCGMTSNG FTIADPDDRG MLDMCGFDTG ALDVIRNFTL DMI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.