Details for: TAF7
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 375.2606
Cell Significance Index: -58.3700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 167.8341
Cell Significance Index: -42.5700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 157.3744
Cell Significance Index: -64.8300 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 136.7018
Cell Significance Index: -64.5400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 123.0984
Cell Significance Index: -63.3200 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 96.5840
Cell Significance Index: -64.8100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 50.5776
Cell Significance Index: -62.3600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.9909
Cell Significance Index: -48.2000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 16.4240
Cell Significance Index: -64.8100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.1882
Cell Significance Index: -46.6500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.8681
Cell Significance Index: -17.2200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.0952
Cell Significance Index: 84.2500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.8933
Cell Significance Index: 100.5400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.7777
Cell Significance Index: 145.8400 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 2.3833
Cell Significance Index: 18.3700 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.3296
Cell Significance Index: 18.6000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.1838
Cell Significance Index: 299.8900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.9155
Cell Significance Index: 123.5800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.9099
Cell Significance Index: 33.7500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.9067
Cell Significance Index: 39.9100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.8681
Cell Significance Index: 53.5500 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.6290
Cell Significance Index: 208.8300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.5807
Cell Significance Index: 74.2900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.4879
Cell Significance Index: 242.0000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4153
Cell Significance Index: 772.9200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.4112
Cell Significance Index: 166.4300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.3313
Cell Significance Index: 35.0100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2550
Cell Significance Index: 56.8900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2113
Cell Significance Index: 119.8200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.1895
Cell Significance Index: 525.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.0287
Cell Significance Index: 126.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.9903
Cell Significance Index: 127.9400 - Cell Name: peg cell (CL4033014)
Fold Change: 0.9674
Cell Significance Index: 22.3500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.8644
Cell Significance Index: 11.0700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.8176
Cell Significance Index: 147.3900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8072
Cell Significance Index: 728.8800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.7614
Cell Significance Index: 35.5000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.7150
Cell Significance Index: 53.2900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6825
Cell Significance Index: 19.6700 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.6577
Cell Significance Index: 7.1500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.6459
Cell Significance Index: 7.7000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6338
Cell Significance Index: 125.7800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.4710
Cell Significance Index: 33.3100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4649
Cell Significance Index: 88.4800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4178
Cell Significance Index: 83.8200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4159
Cell Significance Index: 45.2400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.3327
Cell Significance Index: 3.7800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2572
Cell Significance Index: 16.2100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2539
Cell Significance Index: 6.7800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2258
Cell Significance Index: 11.7300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1962
Cell Significance Index: 11.0100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1869
Cell Significance Index: 67.0600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1461
Cell Significance Index: 24.9500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0905
Cell Significance Index: 3.1800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0499
Cell Significance Index: 0.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0160
Cell Significance Index: 11.7600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0022
Cell Significance Index: 2.9300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0066
Cell Significance Index: -12.4800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0078
Cell Significance Index: -5.8000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0120
Cell Significance Index: -9.0900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0240
Cell Significance Index: -0.6700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0265
Cell Significance Index: -48.9400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0314
Cell Significance Index: -48.3600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0361
Cell Significance Index: -22.5200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0488
Cell Significance Index: -4.9800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0521
Cell Significance Index: -33.0900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0596
Cell Significance Index: -33.6400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1099
Cell Significance Index: -49.9000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1202
Cell Significance Index: -7.3900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1213
Cell Significance Index: -25.5500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1553
Cell Significance Index: -17.7300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1758
Cell Significance Index: -50.5900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1889
Cell Significance Index: -1.2800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2189
Cell Significance Index: -5.3400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2247
Cell Significance Index: -26.1900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2608
Cell Significance Index: -29.8800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3112
Cell Significance Index: -7.9500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3268
Cell Significance Index: -47.5000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3801
Cell Significance Index: -29.1700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4020
Cell Significance Index: -27.0300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4126
Cell Significance Index: -13.2200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.5165
Cell Significance Index: -7.7400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.5314
Cell Significance Index: -7.2500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5571
Cell Significance Index: -16.3600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5848
Cell Significance Index: -46.3200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6069
Cell Significance Index: -63.1900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.6305
Cell Significance Index: -15.7600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.6652
Cell Significance Index: -11.4000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7150
Cell Significance Index: -4.3200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.7188
Cell Significance Index: -19.2600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.7441
Cell Significance Index: -16.1200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.7525
Cell Significance Index: -10.5600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8099
Cell Significance Index: -21.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9556
Cell Significance Index: -58.5900 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -1.0303
Cell Significance Index: -6.4500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.0938
Cell Significance Index: -48.3800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.1676
Cell Significance Index: -21.5800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -1.2999
Cell Significance Index: -25.3700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -1.3093
Cell Significance Index: -49.5800 - Cell Name: theca cell (CL0000503)
Fold Change: -1.3140
Cell Significance Index: -7.7200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1084545750
Symbol: TAF7_HUMAN
Name: Transcription initiation factor TFIID subunit 7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8702684
Title: Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein.
PubMed ID: 8702684
PubMed ID: 7824954
Title: Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators.
PubMed ID: 7824954
PubMed ID: 11340078
Title: The intronless and TATA-less human TAFII55 gene contains a functional initiator and a downstream promoter element.
PubMed ID: 11340078
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10438527
Title: Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription.
PubMed ID: 10438527
PubMed ID: 11592977
Title: TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.
PubMed ID: 11592977
PubMed ID: 15960975
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
PubMed ID: 15960975
PubMed ID: 20937824
Title: Novel functions for TAF7, a regulator of TAF1-independent transcription.
PubMed ID: 20937824
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16415881
Title: Structural basis for the methylation site specificity of SET7/9.
PubMed ID: 16415881
DOI: 10.1038/nsmb1045
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22711989
Title: Phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7.
PubMed ID: 22711989
DOI: 10.1128/mcb.00416-12
PubMed ID: 24036077
Title: Transcriptional coactivator CIITA, a functional homolog of TAF1, has kinase activity.
PubMed ID: 24036077
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 29203640
Title: Transforming Growth Factor beta-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.
PubMed ID: 29203640
DOI: 10.1128/mcb.00449-17
PubMed ID: 25412659
Title: Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
PubMed ID: 25412659
DOI: 10.1038/cr.2014.148
PubMed ID: 27007846
Title: Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.
PubMed ID: 27007846
DOI: 10.1038/nature17394
PubMed ID: 33795473
Title: Structural insights into preinitiation complex assembly on core promoters.
PubMed ID: 33795473
Sequence Information:
- Length: 349
- Mass: 40259
- Checksum: 0AAFD3E33E3CCD6E
- Sequence:
MSKSKDDAPH ELESQFILRL PPEYASTVRR AVQSGHVNLK DRLTIELHPD GRHGIVRVDR VPLASKLVDL PCVMESLKTI DKKTFYKTAD ICQMLVSTVD GDLYPPVEEP VASTDPKASK KKDKDKEKKF IWNHGITLPL KNVRKRRFRK TAKKKYIESP DVEKEVKRLL STDAEAVSTR WEIIAEDETK EAENQGLDIS SPGMSGHRQG HDSLEHDELR EIFNDLSSSS EDEDETQHQD EEDINIIDTE EDLERQLQDK LNESDEQHQE NEGTNQLVMG IQKQIDNMKG KLQETQDRAK RQEDLIMKVE NLALKNRFQA VLDELKQKED REKEQLSSLQ EELESLLEK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.