Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 293.6124
Cell Significance Index: -45.6700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 190.0109
Cell Significance Index: -48.2000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 160.6515
Cell Significance Index: -66.1800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 139.4553
Cell Significance Index: -65.8400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 135.7515
Cell Significance Index: -55.1500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 123.9732
Cell Significance Index: -63.7700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 98.1488
Cell Significance Index: -65.8600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 58.5812
Cell Significance Index: -55.9300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 50.1843
Cell Significance Index: -61.8800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.3432
Cell Significance Index: -46.4600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 16.7687
Cell Significance Index: -66.1700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 13.6287
Cell Significance Index: -41.8600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.1690
Cell Significance Index: -15.6900 - Cell Name: germ cell (CL0000586)
Fold Change: 4.3254
Cell Significance Index: 32.6600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.6368
Cell Significance Index: 104.2500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 3.3078
Cell Significance Index: 35.9600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.8397
Cell Significance Index: 59.4400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.5780
Cell Significance Index: 121.1700 - Cell Name: theca cell (CL0000503)
Fold Change: 2.1872
Cell Significance Index: 12.8500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.1807
Cell Significance Index: 299.4700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.1521
Cell Significance Index: 56.5900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.1494
Cell Significance Index: 74.6900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.8682
Cell Significance Index: 120.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.6478
Cell Significance Index: 212.8800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.6455
Cell Significance Index: 44.7900 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.6407
Cell Significance Index: 13.1000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.6106
Cell Significance Index: 113.9100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.4924
Cell Significance Index: 183.5000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4844
Cell Significance Index: 810.6600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.4694
Cell Significance Index: 264.8800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.3553
Cell Significance Index: 599.1900 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.2625
Cell Significance Index: 161.8400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2622
Cell Significance Index: 58.8500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.2481
Cell Significance Index: 147.1900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.1863
Cell Significance Index: 25.7000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.1849
Cell Significance Index: 62.2100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.9889
Cell Significance Index: 17.4800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9224
Cell Significance Index: 183.0600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.8393
Cell Significance Index: 62.5500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.8324
Cell Significance Index: 43.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.8185
Cell Significance Index: 42.5200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8168
Cell Significance Index: 23.5400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7284
Cell Significance Index: 146.1200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.6533
Cell Significance Index: 17.4500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.6347
Cell Significance Index: 5.8500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5251
Cell Significance Index: 85.4000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.5044
Cell Significance Index: 5.7300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.4520
Cell Significance Index: 77.1800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3617
Cell Significance Index: 39.3400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.3053
Cell Significance Index: 3.9100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2532
Cell Significance Index: 48.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2485
Cell Significance Index: 224.3300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2227
Cell Significance Index: 79.8900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1836
Cell Significance Index: 5.1300 - Cell Name: peg cell (CL4033014)
Fold Change: 0.1565
Cell Significance Index: 3.6200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1219
Cell Significance Index: 3.5800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0064
Cell Significance Index: 4.6900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0012
Cell Significance Index: 0.0200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0014
Cell Significance Index: -1.0300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0071
Cell Significance Index: -0.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0094
Cell Significance Index: -0.9300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0116
Cell Significance Index: -21.8200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0250
Cell Significance Index: -18.5100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0318
Cell Significance Index: -58.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0367
Cell Significance Index: -22.9300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0385
Cell Significance Index: -59.3000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0464
Cell Significance Index: -63.1200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0514
Cell Significance Index: -35.5200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0519
Cell Significance Index: -32.9600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0628
Cell Significance Index: -6.4200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0635
Cell Significance Index: -35.8300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0857
Cell Significance Index: -5.2700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1068
Cell Significance Index: -48.4800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1403
Cell Significance Index: -29.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1643
Cell Significance Index: -18.8300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1748
Cell Significance Index: -5.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1759
Cell Significance Index: -50.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1905
Cell Significance Index: -22.2100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2226
Cell Significance Index: -14.0300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2564
Cell Significance Index: -6.5500 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.2913
Cell Significance Index: -1.7600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3067
Cell Significance Index: -17.2100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3224
Cell Significance Index: -46.8600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3465
Cell Significance Index: -39.5500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3972
Cell Significance Index: -10.6300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.4327
Cell Significance Index: -19.6200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5076
Cell Significance Index: -34.1300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5381
Cell Significance Index: -42.6200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.5583
Cell Significance Index: -14.9600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6328
Cell Significance Index: -65.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.6753
Cell Significance Index: -51.8200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.7044
Cell Significance Index: -9.6100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8616
Cell Significance Index: -52.8200 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.8658
Cell Significance Index: -5.4200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.9155
Cell Significance Index: -19.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.1058
Cell Significance Index: -18.9500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.1866
Cell Significance Index: -34.9500 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -1.2156
Cell Significance Index: -8.7300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.2290
Cell Significance Index: -54.3600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.2345
Cell Significance Index: -12.7800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 365594821
Symbol: TCPA_HUMAN
Name: T-complex protein 1 subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2377466
Title: Nucleotide and amino-acid sequence of human testis-derived TCP1.
PubMed ID: 2377466
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 3653076
Title: The human homologue of the mouse T-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region.
PubMed ID: 3653076
PubMed ID: 1630492
Title: T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol.
PubMed ID: 1630492
DOI: 10.1038/358249a0
PubMed ID: 14532270
Title: A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.
PubMed ID: 14532270
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20080638
Title: BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
PubMed ID: 20080638
PubMed ID: 21098288
Title: Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.
PubMed ID: 21098288
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 25467444
Title: Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
PubMed ID: 25467444
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 33144677
Title: Dlec1 is required for spermatogenesis and male fertility in mice.
PubMed ID: 33144677
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 556
- Mass: 60344
- Checksum: 486ECA836EA258A1
- Sequence:
MEGPLSVFGD RSTGETIRSQ NVMAAASIAN IVKSSLGPVG LDKMLVDDIG DVTITNDGAT ILKLLEVEHP AAKVLCELAD LQDKEVGDGT TSVVIIAAEL LKNADELVKQ KIHPTSVISG YRLACKEAVR YINENLIVNT DELGRDCLIN AAKTSMSSKI IGINGDFFAN MVVDAVLAIK YTDIRGQPRY PVNSVNILKA HGRSQMESML ISGYALNCVV GSQGMPKRIV NAKIACLDFS LQKTKMKLGV QVVITDPEKL DQIRQRESDI TKERIQKILA TGANVILTTG GIDDMCLKYF VEAGAMAVRR VLKRDLKRIA KASGATILST LANLEGEETF EAAMLGQAEE VVQERICDDE LILIKNTKAR TSASIILRGA NDFMCDEMER SLHDALCVVK RVLESKSVVP GGGAVEAALS IYLENYATSM GSREQLAIAE FARSLLVIPN TLAVNAAQDS TDLVAKLRAF HNEAQVNPER KNLKWIGLDL SNGKPRDNKQ AGVFEPTIVK VKSLKFATEA AITILRIDDL IKLHPESKDD KHGSYEDAVH SGALND
Genular Protein ID: 3780249750
Symbol: E7EQR6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 401
- Mass: 43886
- Checksum: AAE1912CB35EBF2B
- Sequence:
MSSKIIGING DFFANMVVDA VLAIKYTDIR GQPRYPVNSV NILKAHGRSQ MESMLISGYA LNCVVGSQGM PKRIVNAKIA CLDFSLQKTK MKLGVQVVIT DPEKLDQIRQ RESDITKERI QKILATGANV ILTTGGIDDM CLKYFVEAGA MAVRRVLKRD LKRIAKASGA TILSTLANLE GEETFEAAML GQAEEVVQER ICDDELILIK NTKARTSASI ILRGANDFMC DEMERSLHDA LCVVKRVLES KSVVPGGGAV EAALSIYLEN YATSMGSREQ LAIAEFARSL LVIPNTLAVN AAQDSTDLVA KLRAFHNEAQ VNPERKNLKW IGLDLSNGKP RDNKQAGVFE PTIVKVKSLK FATEAAITIL RIDDLIKLHP ESKDDKHGSY EDAVHSGALN D
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.