Details for: CCT3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 429.7785
Cell Significance Index: -66.8500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 232.7283
Cell Significance Index: -59.0300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 202.5986
Cell Significance Index: -83.4600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 172.3493
Cell Significance Index: -81.3700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 164.7848
Cell Significance Index: -66.9500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 151.8123
Cell Significance Index: -78.0900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 121.5310
Cell Significance Index: -81.5500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 71.5219
Cell Significance Index: -68.2900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 64.6576
Cell Significance Index: -79.7200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 22.8418
Cell Significance Index: -61.1900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 21.0578
Cell Significance Index: -83.1000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.5243
Cell Significance Index: -53.8300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 5.8239
Cell Significance Index: 402.7500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 5.2339
Cell Significance Index: 609.9500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 4.0455
Cell Significance Index: 43.9800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 3.4465
Cell Significance Index: 3111.9200 - Cell Name: kidney cell (CL1000497)
Fold Change: 3.2614
Cell Significance Index: 26.0400 - Cell Name: germ cell (CL0000586)
Fold Change: 3.0746
Cell Significance Index: 23.2200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.6288
Cell Significance Index: 69.1300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.5543
Cell Significance Index: 53.4700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.5368
Cell Significance Index: 119.2300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.4602
Cell Significance Index: 85.4900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.4233
Cell Significance Index: 65.9600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.4140
Cell Significance Index: 1318.3400 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.2581
Cell Significance Index: 291.7300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.2105
Cell Significance Index: 438.6800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.1727
Cell Significance Index: 298.3700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.1639
Cell Significance Index: 25.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.0705
Cell Significance Index: 146.4400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.0044
Cell Significance Index: 129.3200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.0022
Cell Significance Index: 246.1900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.9925
Cell Significance Index: 359.1800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.8553
Cell Significance Index: 17.0900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.8105
Cell Significance Index: 114.1100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.5627
Cell Significance Index: 184.2900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.5367
Cell Significance Index: 114.5300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.5328
Cell Significance Index: 677.6800 - Cell Name: peg cell (CL4033014)
Fold Change: 1.4102
Cell Significance Index: 32.5800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1363
Cell Significance Index: 59.0300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.0678
Cell Significance Index: 214.2000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.0634
Cell Significance Index: 31.2300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.0215
Cell Significance Index: 53.2100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.0052
Cell Significance Index: 46.8700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.9946
Cell Significance Index: 52.2200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9316
Cell Significance Index: 119.4300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8625
Cell Significance Index: 24.8500 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.8433
Cell Significance Index: 9.5800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.7737
Cell Significance Index: 20.6600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.7579
Cell Significance Index: 129.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.7016
Cell Significance Index: 15.2000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.6761
Cell Significance Index: 19.3800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.6208
Cell Significance Index: 222.6700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4515
Cell Significance Index: 20.4700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3417
Cell Significance Index: 55.5700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2523
Cell Significance Index: 7.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1552
Cell Significance Index: 29.5300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0975
Cell Significance Index: 5.9900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0962
Cell Significance Index: 3.3800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0860
Cell Significance Index: 1.5200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0754
Cell Significance Index: 2.0200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0672
Cell Significance Index: 6.6500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0525
Cell Significance Index: 38.4800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0326
Cell Significance Index: 0.5500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0199
Cell Significance Index: 15.0400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0185
Cell Significance Index: -11.5400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0216
Cell Significance Index: -40.6400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0315
Cell Significance Index: -23.3200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0359
Cell Significance Index: -66.2400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0384
Cell Significance Index: -52.2100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0409
Cell Significance Index: -63.0000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0493
Cell Significance Index: -1.5800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.0574
Cell Significance Index: -0.7300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0641
Cell Significance Index: -40.7000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0678
Cell Significance Index: -6.9300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0806
Cell Significance Index: -2.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0929
Cell Significance Index: -52.4000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1135
Cell Significance Index: -51.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1677
Cell Significance Index: -35.3300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1774
Cell Significance Index: -3.0400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2111
Cell Significance Index: -24.1900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2232
Cell Significance Index: -64.2200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2825
Cell Significance Index: -15.8500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3243
Cell Significance Index: -4.8600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3834
Cell Significance Index: -55.7400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4156
Cell Significance Index: -31.9000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.4436
Cell Significance Index: -2.6800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5160
Cell Significance Index: -58.9000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5715
Cell Significance Index: -38.4300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6308
Cell Significance Index: -49.9600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.7365
Cell Significance Index: -19.7000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.7838
Cell Significance Index: -81.6100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.8722
Cell Significance Index: -11.9000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.2236
Cell Significance Index: -75.0200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3573
Cell Significance Index: -34.8900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.3954
Cell Significance Index: -14.4500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.4325
Cell Significance Index: -63.3700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.5234
Cell Significance Index: -44.8700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -1.7215
Cell Significance Index: -65.1900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.7392
Cell Significance Index: -49.6300 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.7679
Cell Significance Index: -10.8800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2823290949
Symbol: TCPG_HUMAN
Name: T-complex protein 1 subunit gamma
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8573069
Title: Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma.
PubMed ID: 8573069
DOI: 10.1042/bj3130381
PubMed ID: 8001976
Title: Assignment of the human homologue of the mTRiC-P5 gene (TRIC5) to band 1q23 by fluorescence in situ hybridization.
PubMed ID: 8001976
PubMed ID: 14532270
Title: A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.
PubMed ID: 14532270
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20080638
Title: BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
PubMed ID: 20080638
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 25467444
Title: Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
PubMed ID: 25467444
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 33144677
Title: Dlec1 is required for spermatogenesis and male fertility in mice.
PubMed ID: 33144677
Sequence Information:
- Length: 545
- Mass: 60534
- Checksum: 0A528762EF24F36B
- Sequence:
MMGHRPVLVL SQNTKRESGR KVQSGNINAA KTIADIIRTC LGPKSMMKML LDPMGGIVMT NDGNAILREI QVQHPAAKSM IEISRTQDEE VGDGTTSVII LAGEMLSVAE HFLEQQMHPT VVISAYRKAL DDMISTLKKI SIPVDISDSD MMLNIINSSI TTKAISRWSS LACNIALDAV KMVQFEENGR KEIDIKKYAR VEKIPGGIIE DSCVLRGVMI NKDVTHPRMR RYIKNPRIVL LDSSLEYKKG ESQTDIEITR EEDFTRILQM EEEYIQQLCE DIIQLKPDVV ITEKGISDLA QHYLMRANIT AIRRVRKTDN NRIARACGAR IVSRPEELRE DDVGTGAGLL EIKKIGDEYF TFITDCKDPK ACTILLRGAS KEILSEVERN LQDAMQVCRN VLLDPQLVPG GGASEMAVAH ALTEKSKAMT GVEQWPYRAV AQALEVIPRT LIQNCGASTI RLLTSLRAKH TQENCETWGV NGETGTLVDM KELGIWEPLA VKLQTYKTAV ETAVLLLRID DIVSGHKKKG DDQSRQGGAP DAGQE
Genular Protein ID: 1927609812
Symbol: Q59H77_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 577
- Mass: 63576
- Checksum: 29E5AA6307107793
- Sequence:
EAAFSGLLSG SLSPEGSAGS PSSGYPALHR VAMMGHRPVL VLSQNTKRES GRKVQSGNIN AAKTIADIIR TCLGPKSMMK MLLDPMGGIV MTNDGNAILR EIQVQHPAAK SMIEISRTQD EEVGDGTTSV IILAGEMLSV AEHFLEQQMH PTVVISAYRK ALDDMISTLK KISIPVDISD SDMMLNIINS SITTKAISRW SSLACNIALD AVKMVQFEEN GRKEIDIKKY ARVEKIPGGI IEDSCVLRGV MINKDVTHPR MRRYIKNPRI VLLDSSLEYK KGESQTDIEI TREEDFTRIL QMEEEYIQQL CEDIIQLKPD VVITEKGISD LAQHYLMRAN ITAIRRVRKT DNNRIARACG ARIVSRPEEL REDDVGTGAG LLEIKKIGDE YFTFITDCKD PKACTILLRG ASKEILSEVE RNLQDAMQVC RNVLLDPQLV PGGGASEMAV AHALTEKSKA MTGVEQWPYR AVAQALEVIP RTLIQNCGAS TIRLLTSLRA KHTQENCETW GVNGETGTLV DMKELGIWEP LAVKLQTYKT AVETAVLLLR IDDIVSGHKK KGDDQSRQGG APDAGQE
Genular Protein ID: 2359054202
Symbol: B3KX11_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 522
- Mass: 57946
- Checksum: BC05982B7448414B
- Sequence:
MMGHRPVLVL SQNTKRESGR KVQSGNINAA KTIADIIRTC LGPKSMMKML LDPMGGIVMT NDGNAILREI QVQHPAAKSM IEISRTQDEE VGDGTTTVVI SAYRKALDDM ISTLKKISIP VDISDSDMML NIINSSITTK AISRWSSLAC NIALDAVKMV QFEENGRKEI DIKKYARVEK IPGGIIEDSC VLRGVMINKD VTHPRMRRHI KNPRIVLLDS SLEYKKGESQ TDIEITREED FTRILQMEEE YIQQLCEDII QLKPDVVITE KGISDLAQHY LMRANITAIR RVRKTDNNRI ARACGARIVS RPEELREDDV GTGAGLLEIK KIGDEYFTFI TDCKDPKACT ILLRGASKEI LSEVERNLQD AMQVCRNVLL DPQLVPGGGA SEMAVAHALT EKSKAMTGVE QWPYRAVAQA LEVIPRTLIQ NCGASTIRLL TSLRAKHTQE NCETWGVNGE TGTLVDMKEL GIWEPLAVKL QTYKTAVETA VLLLRIDDIV SGHKKKGDDQ SRQGGAPDAG QE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.