Details for: UBA7

Gene ID: 7318

Symbol: UBA7

Ensembl ID: ENSG00000182179

Description: ubiquitin like modifier activating enzyme 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 61.4934
    Cell Significance Index: -9.5700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 23.3350
    Cell Significance Index: -9.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 23.0449
    Cell Significance Index: -10.8800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 22.2110
    Cell Significance Index: -11.4300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 22.0388
    Cell Significance Index: -5.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.7778
    Cell Significance Index: -10.2900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.2404
    Cell Significance Index: -10.1600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.3437
    Cell Significance Index: -10.2700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.2365
    Cell Significance Index: -8.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 3.0411
    Cell Significance Index: 578.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.6305
    Cell Significance Index: -10.3800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1872
    Cell Significance Index: 129.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1024
    Cell Significance Index: 66.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0819
    Cell Significance Index: 175.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9931
    Cell Significance Index: 13.5500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8522
    Cell Significance Index: 44.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8152
    Cell Significance Index: 52.6000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6319
    Cell Significance Index: 570.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5985
    Cell Significance Index: 31.0900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5964
    Cell Significance Index: 12.9200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4688
    Cell Significance Index: 13.1000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.4520
    Cell Significance Index: 8.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4451
    Cell Significance Index: 11.9100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.4333
    Cell Significance Index: 6.5300
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.3893
    Cell Significance Index: 3.2200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.3400
    Cell Significance Index: 39.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2903
    Cell Significance Index: 8.3700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2875
    Cell Significance Index: 33.9000
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.2799
    Cell Significance Index: 1.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2775
    Cell Significance Index: 7.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2222
    Cell Significance Index: 10.0700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2033
    Cell Significance Index: 9.4800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1894
    Cell Significance Index: 18.7400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1559
    Cell Significance Index: 19.9900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1534
    Cell Significance Index: 4.5100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1459
    Cell Significance Index: 17.9400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1359
    Cell Significance Index: 4.7800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1126
    Cell Significance Index: 20.3100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1054
    Cell Significance Index: 2.8700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0902
    Cell Significance Index: 4.5600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0601
    Cell Significance Index: 1.2800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0370
    Cell Significance Index: 4.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0342
    Cell Significance Index: 15.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0279
    Cell Significance Index: 15.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0227
    Cell Significance Index: 3.1200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0197
    Cell Significance Index: 0.4600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0001
    Cell Significance Index: 0.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0034
    Cell Significance Index: -2.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0035
    Cell Significance Index: -0.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0042
    Cell Significance Index: -0.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0048
    Cell Significance Index: -8.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0054
    Cell Significance Index: -8.3800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0061
    Cell Significance Index: -3.8600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0072
    Cell Significance Index: -4.9500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0091
    Cell Significance Index: -1.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0091
    Cell Significance Index: -12.4100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0136
    Cell Significance Index: -9.9400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0138
    Cell Significance Index: -0.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0159
    Cell Significance Index: -11.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0189
    Cell Significance Index: -8.6000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0191
    Cell Significance Index: -3.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0205
    Cell Significance Index: -11.5800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0234
    Cell Significance Index: -0.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0252
    Cell Significance Index: -3.6700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0262
    Cell Significance Index: -9.4100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0299
    Cell Significance Index: -0.6200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0321
    Cell Significance Index: -2.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0350
    Cell Significance Index: -4.0200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0360
    Cell Significance Index: -10.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0365
    Cell Significance Index: -1.1700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0376
    Cell Significance Index: -2.6600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0431
    Cell Significance Index: -8.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0570
    Cell Significance Index: -12.0000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0612
    Cell Significance Index: -1.2000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0619
    Cell Significance Index: -0.5700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0735
    Cell Significance Index: -1.2300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0934
    Cell Significance Index: -7.1700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0978
    Cell Significance Index: -10.1800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1230
    Cell Significance Index: -7.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1375
    Cell Significance Index: -10.8900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1483
    Cell Significance Index: -1.5400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1573
    Cell Significance Index: -4.5100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1636
    Cell Significance Index: -11.0000
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.1661
    Cell Significance Index: -1.0400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1705
    Cell Significance Index: -6.9900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1708
    Cell Significance Index: -1.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1723
    Cell Significance Index: -10.8600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1863
    Cell Significance Index: -11.4500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2042
    Cell Significance Index: -11.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2127
    Cell Significance Index: -11.1700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2147
    Cell Significance Index: -2.7500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.2230
    Cell Significance Index: -3.4500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2286
    Cell Significance Index: -8.3900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2399
    Cell Significance Index: -10.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2533
    Cell Significance Index: -6.6600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2547
    Cell Significance Index: -6.8000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2616
    Cell Significance Index: -4.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2799
    Cell Significance Index: -10.6000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2828
    Cell Significance Index: -4.0500
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: -0.2884
    Cell Significance Index: -0.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** UBA7 is a ubiquitin-like modifier activating enzyme that catalyzes the activation of ubiquitin-like modifiers (Ulm). These modifiers are essential for the covalent modification of proteins, which regulates their activity, localization, and stability. UBA7 is highly conserved across species, indicating its essential role in maintaining cellular homeostasis. The enzyme's ability to activate Um suggests its involvement in various cellular processes, including protein degradation, antigen processing, and antiviral responses. **Pathways and Functions:** UBA7 is implicated in several key pathways, including: 1. **Adaptive Immune System:** UBA7 is essential for the activation of Um, which is required for the proper functioning of immune cells, such as T cells and B cells. 2. **Antigen Processing:** UBA7 is involved in the processing and presentation of antigens to the immune system, particularly through the major histocompatibility complex (MHC) class I pathway. 3. **Antiviral Mechanism:** UBA7 is required for the activation of Um, which plays a crucial role in the antiviral response, particularly through the induction of interferon-alpha/beta. 4. **Cytokine Signaling:** UBA7 is involved in the regulation of cytokine signaling, which is essential for the proper functioning of the immune system. **Functions:** UBA7's primary function is to activate Um, which is required for the covalent modification of proteins. This modification can regulate protein activity, localization, and stability, which is essential for various cellular processes, including: 1. **Protein Degradation:** UBA7's activation of Um is required for the degradation of proteins, which is essential for maintaining cellular homeostasis. 2. **Antigen Processing:** UBA7's involvement in antigen processing and presentation is critical for the activation of immune cells. 3. **Antiviral Mechanism:** UBA7's activation of Um is essential for the induction of interferon-alpha/beta, which is a key antiviral response. **Clinical Significance:** UBA7's dysregulation has been implicated in various diseases, including: 1. **Autoimmune Disorders:** UBA7's dysregulation has been linked to autoimmune disorders, such as rheumatoid arthritis and lupus. 2. **Cancer:** UBA7's activation of Um has been implicated in the regulation of protein degradation, which is essential for cancer cell growth and survival. 3. **Neurological Disorders:** UBA7's dysregulation has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, UBA7 is a crucial enzyme in the regulation of the immune system, involved in various cellular processes, including protein modification, antigen processing, and antiviral mechanisms. Its dysregulation has been implicated in various diseases, highlighting the importance of UBA7 in maintaining immune homeostasis and preventing disease. Further research is necessary to fully elucidate the role of UBA7 in human disease and to develop therapeutic strategies targeting this enzyme.

Genular Protein ID: 898963362

Symbol: UBA7_HUMAN

Name: Ubiquitin-like modifier-activating enzyme 7

UniProtKB Accession Codes:

P41226 Q9BRB2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EMDB 6 Ensembl 1 GO 12 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8327486

Title: A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme.

PubMed ID: 8327486

DOI: 10.1073/pnas.90.13.6071

PubMed ID: 7734949

Title: The genomic structure of the human UBE1L gene.

PubMed ID: 7734949

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 11157743

Title: Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein.

PubMed ID: 11157743

DOI: 10.1093/emboj/20.3.362

PubMed ID: 16254333

Title: Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo.

PubMed ID: 16254333

DOI: 10.1128/jvi.79.22.13974-13983.2005

PubMed ID: 19073728

Title: ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus.

PubMed ID: 19073728

DOI: 10.1128/jvi.01590-08

PubMed ID: 20133869

Title: ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells.

PubMed ID: 20133869

DOI: 10.1073/pnas.0909144107

PubMed ID: 22693631

Title: Covalent protein modification with ISG15 via a conserved cysteine in the hinge region.

PubMed ID: 22693631

DOI: 10.1371/journal.pone.0038294

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27545325

Title: Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification.

PubMed ID: 27545325

DOI: 10.1038/ncomms12513

PubMed ID: 27564865

Title: Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators.

PubMed ID: 27564865

DOI: 10.1371/journal.ppat.1005850

PubMed ID: 29056542

Title: Inhibition of rabies virus replication by interferon-stimulated gene 15 and its activating enzyme UBA7.

PubMed ID: 29056542

DOI: 10.1016/j.meegid.2017.10.016

PubMed ID: 28035359

Title: ISG15 inhibits cancer cell growth and promotes apoptosis.

PubMed ID: 28035359

DOI: 10.3892/ijmm.2016.2845

PubMed ID: 29743376

Title: Transmembrane Protein pUL50 of Human Cytomegalovirus Inhibits ISGylation by Downregulating UBE1L.

PubMed ID: 29743376

DOI: 10.1128/jvi.00462-18

PubMed ID: 37722521

Title: Rotavirus circumvents the antiviral effects of protein ISGylation via proteasomal degradation of Ube1L.

PubMed ID: 37722521

DOI: 10.1016/j.cellsig.2023.110891

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

Sequence Information:

  • Length: 1012
  • Mass: 111694
  • Checksum: A01E1106D81778EB
  • Sequence:
    • MDALDASKLL DEELYSRQLY VLGSPAMQRI QGARVLVSGL QGLGAEVAKN LVLMGVGSLT 
LHDPHPTCWS DLAAQFLLSE QDLERSRAEA SQELLAQLNR AVQVVVHTGD ITEDLLLDFQ 
VVVLTAAKLE EQLKVGTLCH KHGVCFLAAD TRGLVGQLFC DFGEDFTVQD PTEAEPLTAA 
IQHISQGSPG ILTLRKGANT HYFRDGDLVT FSGIEGMVEL NDCDPRSIHV REDGSLEIGD 
TTTFSRYLRG GAITEVKRPK TVRHKSLDTA LLQPHVVAQS SQEVHHAHCL HQAFCALHKF 
QHLHGRPPQP WDPVDAETVV GLARDLEPLK RTEEEPLEEP LDEALVRTVA LSSAGVLSPM 
VAMLGAVAAQ EVLKAISRKF MPLDQWLYFD ALDCLPEDGE LLPSPEDCAL RGSRYDGQIA 
VFGAGFQEKL RRQHYLLVGA GAIGCELLKV FALVGLGAGN SGGLTVVDMD HIERSNLSRQ 
FLFRSQDVGR PKAEVAAAAA RGLNPDLQVI PLTYPLDPTT EHIYGDNFFS RVDGVAAALD 
SFQARRYVAA RCTHYLKPLL EAGTSGTWGS ATVFMPHVTE AYRAPASAAA SEDAPYPVCT 
VRYFPSTAEH TLQWARHEFE ELFRLSAETI NHHQQAHTSL ADMDEPQTLT LLKPVLGVLR 
VRPQNWQDCV AWALGHWKLC FHYGIKQLLR HFPPNKVLED GTPFWSGPKQ CPQPLEFDTN 
QDTHLLYVLA AANLYAQMHG LPGSQDWTAL RELLKLLPQP DPQQMAPIFA SNLELASASA 
EFGPEQQKEL NKALEVWSVG PPLKPLMFEK DDDSNFHVDF VVAAASLRCQ NYGIPPVNRA 
QSKRIVGQII PAIATTTAAV AGLLGLELYK VVSGPRPRSA FRHSYLHLAE NYLIRYMPFA 
PAIQTFHHLK WTSWDRLKVP AGQPERTLES LLAHLQEQHG LRVRILLHGS ALLYAAGWSP 
EKQAQHLPLR VTELVQQLTG QAPAPGQRVL VLELSCEGDD EDTAFPPLHY EL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.