Details for: DEK
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 425.5997
Cell Significance Index: -66.2000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 330.5921
Cell Significance Index: -83.8500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 267.1820
Cell Significance Index: -110.0700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 231.7194
Cell Significance Index: -109.4000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 221.1407
Cell Significance Index: -89.8400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 197.1285
Cell Significance Index: -101.4000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 163.7651
Cell Significance Index: -109.8900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 94.7794
Cell Significance Index: -90.4900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 81.3168
Cell Significance Index: -100.2600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 33.0700
Cell Significance Index: -88.5900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 26.6976
Cell Significance Index: -105.3500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 24.0244
Cell Significance Index: -73.7900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.3889
Cell Significance Index: -33.6800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 5.9299
Cell Significance Index: 158.6200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 3.5423
Cell Significance Index: 123.1000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 3.2453
Cell Significance Index: 382.7200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.6235
Cell Significance Index: 322.5800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.3794
Cell Significance Index: 326.7600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.9817
Cell Significance Index: 357.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.9768
Cell Significance Index: 873.9900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.9378
Cell Significance Index: 1058.2900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.8941
Cell Significance Index: 122.2000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.8829
Cell Significance Index: 51.2500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.8636
Cell Significance Index: 20.2600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.8152
Cell Significance Index: 33.5500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.7582
Cell Significance Index: 98.6600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.7501
Cell Significance Index: 46.7300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.7079
Cell Significance Index: 80.2700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.6754
Cell Significance Index: 182.2300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.3970
Cell Significance Index: 98.8000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.3772
Cell Significance Index: 273.3100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.1989
Cell Significance Index: 55.9000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.1869
Cell Significance Index: 53.8000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.0903
Cell Significance Index: 313.7100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.9266
Cell Significance Index: 19.4000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.8802
Cell Significance Index: 112.8400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.8626
Cell Significance Index: 9.8000 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.8495
Cell Significance Index: 109.7500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6934
Cell Significance Index: 68.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.5701
Cell Significance Index: 14.9900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3985
Cell Significance Index: 29.7000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3759
Cell Significance Index: 71.5300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3281
Cell Significance Index: 65.8300 - Cell Name: peg cell (CL4033014)
Fold Change: 0.2634
Cell Significance Index: 6.0900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2474
Cell Significance Index: 42.2400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2251
Cell Significance Index: 155.6600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2017
Cell Significance Index: 72.3500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1996
Cell Significance Index: 12.5800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1586
Cell Significance Index: 143.2300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0848
Cell Significance Index: 5.2100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0482
Cell Significance Index: 2.5100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0245
Cell Significance Index: 0.4100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0238
Cell Significance Index: 36.7000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0148
Cell Significance Index: 0.7700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0097
Cell Significance Index: 7.3300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0045
Cell Significance Index: 0.1300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0014
Cell Significance Index: -2.6600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0022
Cell Significance Index: -1.6400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0124
Cell Significance Index: -22.8500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0153
Cell Significance Index: -11.3100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0353
Cell Significance Index: -1.1300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0400
Cell Significance Index: -54.4500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0595
Cell Significance Index: -37.7600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0667
Cell Significance Index: -6.8100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0715
Cell Significance Index: -32.4400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0902
Cell Significance Index: -56.3500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1297
Cell Significance Index: -73.1300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1583
Cell Significance Index: -8.3100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.1812
Cell Significance Index: -29.4800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1991
Cell Significance Index: -4.2400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2420
Cell Significance Index: -50.9800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3082
Cell Significance Index: -35.3100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3155
Cell Significance Index: -9.0900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3718
Cell Significance Index: -10.3900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.3981
Cell Significance Index: -13.9900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4255
Cell Significance Index: -61.8500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.5160
Cell Significance Index: -10.0700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5435
Cell Significance Index: -13.5900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5938
Cell Significance Index: -17.4400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5950
Cell Significance Index: -69.3400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6404
Cell Significance Index: -16.3600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.7245
Cell Significance Index: -55.6000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7531
Cell Significance Index: -4.5500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.7729
Cell Significance Index: -88.2300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.9005
Cell Significance Index: -19.5100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.9345
Cell Significance Index: -12.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9350
Cell Significance Index: -74.0500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.9425
Cell Significance Index: -98.1400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.0729
Cell Significance Index: -74.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.2076
Cell Significance Index: -31.0400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.2244
Cell Significance Index: -61.8800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.3330
Cell Significance Index: -23.5600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.3643
Cell Significance Index: -23.3800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.4936
Cell Significance Index: -100.4300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.5454
Cell Significance Index: -94.7500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.7758
Cell Significance Index: -52.3100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -1.8741
Cell Significance Index: -22.3400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -1.9107
Cell Significance Index: -78.2900 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -1.9953
Cell Significance Index: -16.7600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -2.1815
Cell Significance Index: -80.0800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1451792518
Symbol: DEK_HUMAN
Name: Protein DEK
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1549122
Title: The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.
PubMed ID: 1549122
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11118221
Title: The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.
PubMed ID: 11118221
PubMed ID: 12140263
Title: Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.
PubMed ID: 12140263
PubMed ID: 15199154
Title: Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK.
PubMed ID: 15199154
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16603771
Title: The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.
PubMed ID: 16603771
PubMed ID: 17524367
Title: The distribution of the DEK protein in mammalian chromatin.
PubMed ID: 17524367
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19695025
Title: Proteome analysis of human nuclear insoluble fractions.
PubMed ID: 19695025
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28190768
Title: Serine ADP-ribosylation depends on HPF1.
PubMed ID: 28190768
PubMed ID: 15238633
Title: Solution NMR structure of the C-terminal domain of the human protein DEK.
PubMed ID: 15238633
DOI: 10.1110/ps.04797104
PubMed ID: 18227428
Title: Solution NMR structure of the N-terminal domain of the human DEK protein.
PubMed ID: 18227428
DOI: 10.1110/ps.073244108
Sequence Information:
- Length: 375
- Mass: 42674
- Checksum: C07D22B37B719A23
- Sequence:
MSASAPAAEG EGTPTQPASE KEPEMPGPRE ESEEEEDEDD EEEEEEEKEK SLIVEGKREK KKVERLTMQV SSLQREPFTI AQGKGQKLCE IERIHFFLSK KKTDELRNLH KLLYNRPGTV SSLKKNVGQF SGFPFEKGSV QYKKKEEMLK KFRNAMLKSI CEVLDLERSG VNSELVKRIL NFLMHPKPSG KPLPKSKKTC SKGSKKERNS SGMARKAKRT KCPEILSDES SSDEDEKKNK EESSDDEDKE SEEEPPKKTA KREKPKQKAT SKSKKSVKSA NVKKADSSTT KKNQNSSKKE SESEDSSDDE PLIKKLKKPP TDEELKETIK KLLASANLEE VTMKQICKKV YENYPTYDLT ERKDFIKTTV KELIS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.