Details for: ANP32A

Gene ID: 8125

Symbol: ANP32A

Ensembl ID: ENSG00000140350

Description: acidic nuclear phosphoprotein 32 family member A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 379.3752
    Cell Significance Index: -59.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 225.2769
    Cell Significance Index: -57.1400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 166.3804
    Cell Significance Index: -68.5400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 151.7614
    Cell Significance Index: -71.6500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 148.8589
    Cell Significance Index: -60.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 134.8600
    Cell Significance Index: -69.3700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 106.8221
    Cell Significance Index: -71.6800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 64.3157
    Cell Significance Index: -61.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 57.5041
    Cell Significance Index: -70.9000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.2310
    Cell Significance Index: -56.8800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.6972
    Cell Significance Index: -73.7800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.5780
    Cell Significance Index: -53.9900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.5365
    Cell Significance Index: -23.0600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.1938
    Cell Significance Index: 23.8500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.9127
    Cell Significance Index: 24.5000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.8850
    Cell Significance Index: 55.3600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.7032
    Cell Significance Index: 109.8800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6460
    Cell Significance Index: 43.9500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.5776
    Cell Significance Index: 12.1600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.5749
    Cell Significance Index: 82.6900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.4657
    Cell Significance Index: 27.0900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.4554
    Cell Significance Index: 171.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4549
    Cell Significance Index: 288.7200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.4070
    Cell Significance Index: 29.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3863
    Cell Significance Index: 249.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.3164
    Cell Significance Index: 718.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2894
    Cell Significance Index: 158.5400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0706
    Cell Significance Index: 147.0300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.0544
    Cell Significance Index: 36.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.9840
    Cell Significance Index: 62.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9212
    Cell Significance Index: 330.4200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9169
    Cell Significance Index: 405.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8537
    Cell Significance Index: 171.2600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8466
    Cell Significance Index: 22.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.7592
    Cell Significance Index: 218.4600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6776
    Cell Significance Index: 31.8500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6561
    Cell Significance Index: 36.8200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6438
    Cell Significance Index: 45.5300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.5674
    Cell Significance Index: 4.5300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5036
    Cell Significance Index: 26.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4747
    Cell Significance Index: 60.8500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3687
    Cell Significance Index: 3.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3355
    Cell Significance Index: 17.4800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3219
    Cell Significance Index: 290.6200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2786
    Cell Significance Index: 12.6300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2063
    Cell Significance Index: 9.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1854
    Cell Significance Index: 35.2900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1012
    Cell Significance Index: 16.4700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1007
    Cell Significance Index: 189.6200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0741
    Cell Significance Index: 12.6600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0649
    Cell Significance Index: 1.5000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0456
    Cell Significance Index: 84.1300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0399
    Cell Significance Index: 61.4600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0342
    Cell Significance Index: 1.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0159
    Cell Significance Index: 21.5800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0116
    Cell Significance Index: 8.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0068
    Cell Significance Index: -0.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0144
    Cell Significance Index: -10.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0202
    Cell Significance Index: -14.9600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0267
    Cell Significance Index: -2.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0308
    Cell Significance Index: -3.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0333
    Cell Significance Index: -21.1600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0464
    Cell Significance Index: -28.9800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0471
    Cell Significance Index: -4.8100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0549
    Cell Significance Index: -24.9300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0633
    Cell Significance Index: -1.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0911
    Cell Significance Index: -51.3500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1019
    Cell Significance Index: -3.2700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1163
    Cell Significance Index: -15.0300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1797
    Cell Significance Index: -37.8400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1917
    Cell Significance Index: -22.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2390
    Cell Significance Index: -6.6800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2632
    Cell Significance Index: -38.2600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2759
    Cell Significance Index: -7.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3265
    Cell Significance Index: -37.4100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.3268
    Cell Significance Index: -2.7500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3689
    Cell Significance Index: -9.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3803
    Cell Significance Index: -8.2400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3855
    Cell Significance Index: -44.0100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4127
    Cell Significance Index: -8.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4740
    Cell Significance Index: -12.6800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5808
    Cell Significance Index: -39.0500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6246
    Cell Significance Index: -65.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6681
    Cell Significance Index: -52.9100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7195
    Cell Significance Index: -12.3300
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.7311
    Cell Significance Index: -10.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7551
    Cell Significance Index: -33.4000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.8624
    Cell Significance Index: -10.2800
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.8750
    Cell Significance Index: -5.7100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.9279
    Cell Significance Index: -27.3300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.9418
    Cell Significance Index: -5.6900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.9535
    Cell Significance Index: -24.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9678
    Cell Significance Index: -36.6500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.0575
    Cell Significance Index: -65.0000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.0740
    Cell Significance Index: -28.7800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1484
    Cell Significance Index: -70.4100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.1837
    Cell Significance Index: -16.1500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.3369
    Cell Significance Index: -13.8400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -1.4540
    Cell Significance Index: -20.3800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.4615
    Cell Significance Index: -47.8500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ANP32A is a nuclear phosphoprotein that belongs to the acidic nuclear phosphoprotein 32 family. It is characterized by its ability to bind to specific DNA sequences, such as AU-rich elements, and regulate mRNA stability. ANP32A is also involved in histone binding, which is essential for chromatin remodeling and gene expression. Furthermore, ANP32A interacts with various signaling pathways, including those involved in apoptosis, metabolism of RNA, and intracellular signal transduction. **Pathways and Functions:** ANP32A is involved in several key pathways, including: 1. **Histone Binding:** ANP32A interacts with histones, which are the main protein components of chromatin. This interaction is crucial for chromatin remodeling and gene expression. 2. **Regulation of mRNA Stability:** ANP32A binds to AU-rich elements in the 3' untranslated region of mRNAs, which regulates mRNA stability and translation. 3. **Intracellular Signaling:** ANP32A interacts with various signaling pathways, including those involved in apoptosis, metabolism of RNA, and intracellular signal transduction. 4. **Nucleocytoplasmic Transport:** ANP32A is involved in the transport of proteins and RNAs between the nucleus and cytoplasm. 5. **Regulation of Apoptotic Process:** ANP32A interacts with pro-apoptotic and anti-apoptotic proteins, which regulates the apoptotic process. **Clinical Significance:** ANP32A has been implicated in various diseases, including: 1. **Cancer:** ANP32A is overexpressed in several types of cancer, including breast, lung, and colon cancer. Its overexpression is associated with poor prognosis and poor response to chemotherapy. 2. **Neurodegenerative Diseases:** ANP32A has been implicated in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 3. **Immune Response:** ANP32A plays a crucial role in regulating the immune response, particularly in the context of T cell activation and apoptosis. In conclusion, ANP32A is a multifunctional protein that plays a crucial role in various cellular processes, including regulation of mRNA stability, histone binding, and intracellular signaling. Its clinical significance is evident in its involvement in various diseases, including cancer, neurodegenerative diseases, and immune response disorders. Further research is needed to fully understand the mechanisms of ANP32A and its potential therapeutic applications.

Genular Protein ID: 618293982

Symbol: AN32A_HUMAN

Name: Acidic nuclear phosphoprotein pp32

UniProtKB Accession Codes:

P39687 B2R6T4 Q53FK4 Q5J8L8 Q7M4N6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8192856

Title: Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.

PubMed ID: 8192856

DOI: 10.1515/bchm3.1994.375.2.113

PubMed ID: 8679524

Title: Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A.

PubMed ID: 8679524

DOI: 10.1021/bi960581y

PubMed ID: 8970164

Title: Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci.

PubMed ID: 8970164

DOI: 10.1091/mbc.7.12.2045

PubMed ID: 9353121

Title: The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.

PubMed ID: 9353121

DOI: 10.1038/40159

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15642345

Title: Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau.

PubMed ID: 15642345

DOI: 10.1016/j.febslet.2004.11.097

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10400610

Title: Identification of sequences required for inhibition of oncogene-mediated transformation by pp32.

PubMed ID: 10400610

DOI: 10.1074/jbc.274.29.20053

PubMed ID: 11163245

Title: Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the Set oncoprotein.

PubMed ID: 11163245

DOI: 10.1016/s0092-8674(01)00196-9

PubMed ID: 11555662

Title: Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.

PubMed ID: 11555662

DOI: 10.1074/jbc.m108137200

PubMed ID: 11360199

Title: Tumor suppression and potentiation by manipulation of pp32 expression.

PubMed ID: 11360199

DOI: 10.1038/sj.onc.1204294

PubMed ID: 11729309

Title: Delineation of mRNA export pathways by the use of cell-permeable peptides.

PubMed ID: 11729309

DOI: 10.1126/science.1064693

PubMed ID: 11830591

Title: Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex.

PubMed ID: 11830591

DOI: 10.1074/jbc.m112455200

PubMed ID: 12628186

Title: Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.

PubMed ID: 12628186

DOI: 10.1016/s0092-8674(03)00150-8

PubMed ID: 12524539

Title: Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.

PubMed ID: 12524539

DOI: 10.1038/ni885

PubMed ID: 15287743

Title: The identification of phosphorylation sites of pp32 and biochemical purification of a cellular pp32-kinase.

PubMed ID: 15287743

DOI: 10.1021/bi0493968

PubMed ID: 15895553

Title: The Anp32 family of proteins containing leucine-rich repeats.

PubMed ID: 15895553

DOI: 10.1080/14734220410019020

PubMed ID: 16818237

Title: The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.

PubMed ID: 16818237

DOI: 10.1016/j.molcel.2006.06.005

PubMed ID: 16341127

Title: Tumor suppressor pp32 represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.

PubMed ID: 16341127

DOI: 10.1038/sj.cdd.4401825

PubMed ID: 17557114

Title: The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.

PubMed ID: 17557114

DOI: 10.1038/sj.embor.7400983

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18180367

Title: Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis.

PubMed ID: 18180367

DOI: 10.1083/jcb.200709030

PubMed ID: 18439902

Title: PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1.

PubMed ID: 18439902

DOI: 10.1016/j.molcel.2008.03.014

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21159877

Title: Foamy virus nuclear RNA export is distinct from that of other retroviruses.

PubMed ID: 21159877

DOI: 10.1128/jvi.01518-10

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30666459

Title: The interaction of cellular protein ANP32A with influenza A virus polymerase component PB2 promotes vRNA synthesis.

PubMed ID: 30666459

DOI: 10.1007/s00705-018-04139-z

PubMed ID: 32694517

Title: Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A.

PubMed ID: 32694517

DOI: 10.1038/s41467-020-17407-x

PubMed ID: 33045004

Title: Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range.

PubMed ID: 33045004

DOI: 10.1371/journal.ppat.1008989

PubMed ID: 33208942

Title: Host ANP32A mediates the assembly of the influenza virus replicase.

PubMed ID: 33208942

DOI: 10.1038/s41586-020-2927-z

PubMed ID: 17567741

Title: The crystal structure of the tumor suppressor protein pp32 (Anp32a): structural insights into Anp32 family of proteins.

PubMed ID: 17567741

DOI: 10.1110/ps.072803507

Sequence Information:

  • Length: 249
  • Mass: 28585
  • Checksum: CA2D1A756FBAEA04
  • Sequence:
    • MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL 
PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL 
FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE EEDEDEEEYD 
EDAQVVEDEE DEDEEEEGEE EDVSGEEEED EEGYNDGEVD DEEDEEELGE EERGQKRKRE 
PEDEGEDDD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.