Details for: EIF3A

Gene ID: 8661

Symbol: EIF3A

Ensembl ID: ENSG00000107581

Description: eukaryotic translation initiation factor 3 subunit A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 488.0896
    Cell Significance Index: -75.9200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 306.2962
    Cell Significance Index: -77.6900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 225.1985
    Cell Significance Index: -92.7700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 214.7112
    Cell Significance Index: -101.3700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 205.8549
    Cell Significance Index: -83.6300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 185.9696
    Cell Significance Index: -95.6600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 151.7536
    Cell Significance Index: -101.8300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 88.2437
    Cell Significance Index: -84.2500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 75.1852
    Cell Significance Index: -92.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 34.1433
    Cell Significance Index: -91.4700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 24.6145
    Cell Significance Index: -97.1300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 22.6017
    Cell Significance Index: -69.4200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.9790
    Cell Significance Index: -37.1600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 4.5042
    Cell Significance Index: 120.4900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.8635
    Cell Significance Index: 103.1600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.4402
    Cell Significance Index: 93.6400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.2673
    Cell Significance Index: 401.7500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.0847
    Cell Significance Index: 556.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.5430
    Cell Significance Index: 175.8600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.3836
    Cell Significance Index: 21.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.3751
    Cell Significance Index: 1297.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.2412
    Cell Significance Index: 105.3400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.2184
    Cell Significance Index: 304.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2176
    Cell Significance Index: 440.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.1995
    Cell Significance Index: 141.9000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.0984
    Cell Significance Index: 228.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.8677
    Cell Significance Index: 97.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.8184
    Cell Significance Index: 63.1900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.7112
    Cell Significance Index: 121.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.6337
    Cell Significance Index: 76.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6267
    Cell Significance Index: 191.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5947
    Cell Significance Index: 705.0700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.4900
    Cell Significance Index: 42.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4662
    Cell Significance Index: 66.4600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.3514
    Cell Significance Index: 38.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.1639
    Cell Significance Index: 198.7500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1458
    Cell Significance Index: 229.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.1411
    Cell Significance Index: 147.4300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.0578
    Cell Significance Index: 11.5000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.0133
    Cell Significance Index: 23.4100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9808
    Cell Significance Index: 885.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9608
    Cell Significance Index: 26.8500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9351
    Cell Significance Index: 69.6900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.8819
    Cell Significance Index: 25.9000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7786
    Cell Significance Index: 14.3900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.7181
    Cell Significance Index: 15.0300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6264
    Cell Significance Index: 32.6300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6141
    Cell Significance Index: 220.2600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5224
    Cell Significance Index: 66.9700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4368
    Cell Significance Index: 24.5100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4342
    Cell Significance Index: 33.3200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4074
    Cell Significance Index: 281.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3795
    Cell Significance Index: 37.5400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2306
    Cell Significance Index: 43.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1828
    Cell Significance Index: 6.4300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1487
    Cell Significance Index: 3.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0881
    Cell Significance Index: 64.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0761
    Cell Significance Index: 143.2500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0389
    Cell Significance Index: 71.7200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0290
    Cell Significance Index: 44.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0259
    Cell Significance Index: 16.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0166
    Cell Significance Index: 12.5400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0011
    Cell Significance Index: 1.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0416
    Cell Significance Index: -30.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0482
    Cell Significance Index: -21.8700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0848
    Cell Significance Index: -52.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0942
    Cell Significance Index: -9.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1184
    Cell Significance Index: -66.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1760
    Cell Significance Index: -2.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.2157
    Cell Significance Index: -35.0800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2178
    Cell Significance Index: -4.2500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2183
    Cell Significance Index: -45.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2911
    Cell Significance Index: -83.7700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3017
    Cell Significance Index: -34.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3141
    Cell Significance Index: -45.6600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4247
    Cell Significance Index: -5.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4650
    Cell Significance Index: -28.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4703
    Cell Significance Index: -54.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5221
    Cell Significance Index: -59.8200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6428
    Cell Significance Index: -43.2300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6503
    Cell Significance Index: -10.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6697
    Cell Significance Index: -35.1600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.6976
    Cell Significance Index: -4.2200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7672
    Cell Significance Index: -19.6000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7742
    Cell Significance Index: -19.9000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8323
    Cell Significance Index: -86.6600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9193
    Cell Significance Index: -72.8100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9198
    Cell Significance Index: -29.4600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.9771
    Cell Significance Index: -61.5900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.0979
    Cell Significance Index: -55.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.2154
    Cell Significance Index: -53.7600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.2601
    Cell Significance Index: -27.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2812
    Cell Significance Index: -78.5500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.4960
    Cell Significance Index: -56.6500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5276
    Cell Significance Index: -38.1900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.6958
    Cell Significance Index: -25.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.7550
    Cell Significance Index: -47.0300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.8361
    Cell Significance Index: -14.6600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.8961
    Cell Significance Index: -21.5400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.1471
    Cell Significance Index: -63.2400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EIF3A exhibits a unique structure, consisting of a single polypeptide chain with a molecular weight of approximately 167 kDa. This protein is highly conserved across species, suggesting its essential role in eukaryotic translation initiation. EIF3A interacts with other components of the eIF3 complex, including eIF3E and eIF3M, to form a heterotrimeric complex that binds to the mRNA cap and recruits the small ribosomal subunit. The protein also exhibits a high degree of specificity for the initiation of translation, as evidenced by its ability to recognize and bind to specific mRNA sequences. **Pathways and Functions:** EIF3A is involved in several key pathways, including: 1. **Cap-dependent translation initiation**: EIF3A binds to the mRNA cap, facilitating the recruitment of the small ribosomal subunit and the initiation of translation. 2. **Eukaryotic translation initiation**: EIF3A plays a critical role in the initiation of translation, recognizing the start codon and recruiting the ribosome to the mRNA. 3. **Ribosomal scanning and start codon recognition**: EIF3A interacts with the ribosome to facilitate the scanning of the mRNA for the start codon. 4. **Translation reinitiation**: EIF3A has been implicated in the reinitiation of translation, allowing for the rapid regulation of protein synthesis. **Clinical Significance:** Dysregulation of EIF3A has been implicated in various diseases, including: 1. **Muscular dystrophy**: Mutations in EIF3A have been associated with certain forms of muscular dystrophy, highlighting its importance in muscle development and function. 2. **Neurological disorders**: EIF3A has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease, where impaired translation initiation may contribute to disease progression. 3. **Cancer**: EIF3A has been shown to play a role in cancer development, where its dysregulation may contribute to tumorigenesis and metastasis. In conclusion, EIF3A is a critical component of the eIF3 complex, essential for the initiation of protein synthesis in eukaryotic cells. Its dysregulation has been implicated in various diseases, highlighting the importance of EIF3A in maintaining cellular homeostasis and development. Further research is needed to fully elucidate the mechanisms by which EIF3A regulates translation initiation and its role in disease pathogenesis.

Genular Protein ID: 1360145783

Symbol: EIF3A_HUMAN

Name: eIF3 p167

UniProtKB Accession Codes:

Q14152 B1AMV5 B4DYS1 F5H335 O00653 Q15778

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EMDB 12 Ensembl 1 EvolutionaryTrace 1 GO 24 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9150439

Title: The human p167 gene encodes a unique structural protein that contains centrosomin A homology and associates with a multicomponent complex.

PubMed ID: 9150439

DOI: 10.1089/dna.1997.16.515

PubMed ID: 9054404

Title: Identification of cDNA clones for the large subunit of eukaryotic translation initiation factor 3. Comparison of homologues from human, Nicotiana tabacum, Caenorhabditis elegans, and Saccharomyces cerevisiae.

PubMed ID: 9054404

DOI: 10.1074/jbc.272.11.7106

PubMed ID: 8590280

Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8590280

DOI: 10.1093/dnares/2.4.167

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 11169732

Title: Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.

PubMed ID: 11169732

DOI: 10.1002/1097-4644(20010315)80:4<483::aid-jcb1002>3.0.co;2-b

PubMed ID: 14519125

Title: Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor eIF3.

PubMed ID: 14519125

DOI: 10.1046/j.1432-1033.2003.03807.x

PubMed ID: 14688252

Title: The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.

PubMed ID: 14688252

DOI: 10.1074/jbc.m312745200

PubMed ID: 15703437

Title: Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.

PubMed ID: 15703437

DOI: 10.1261/rna.7215305

PubMed ID: 16766523

Title: Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.

PubMed ID: 16766523

DOI: 10.1074/jbc.m605418200

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17468741

Title: Human INT6/eIF3e is required for nonsense-mediated mRNA decay.

PubMed ID: 17468741

DOI: 10.1038/sj.embor.7400955

PubMed ID: 18056426

Title: The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation.

PubMed ID: 18056426

DOI: 10.1101/gad.439507

PubMed ID: 17322308

Title: Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

PubMed ID: 17322308

DOI: 10.1074/mcp.m600399-mcp200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18599441

Title: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

PubMed ID: 18599441

DOI: 10.1073/pnas.0801313105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23766293

Title: Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.

PubMed ID: 23766293

DOI: 10.1093/nar/gkt510

PubMed ID: 24357634

Title: The mechanism of translation initiation on Type 1 picornavirus IRESs.

PubMed ID: 24357634

DOI: 10.1002/embj.201386124

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25849773

Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.

PubMed ID: 25849773

DOI: 10.1038/nature14267

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27462815

Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

PubMed ID: 27462815

DOI: 10.1038/nature18954

PubMed ID: 16322461

Title: Structural roles for human translation factor eIF3 in initiation of protein synthesis.

PubMed ID: 16322461

DOI: 10.1126/science.1118977

Sequence Information:

  • Length: 1382
  • Mass: 166569
  • Checksum: 485C01B28D67EBBA
  • Sequence:
    • MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD 
LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKMAEEK TEAAKEESQQ MVLDIEDLDN 
IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ 
AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA 
ISMELWQEAF KAVEDIHGLF SLSKKPPKPQ LMANYYNKVS TVFWKSGNAL FHASTLHRLY 
HLSREMRKNL TQDEMQRMST RVLLATLSIP ITPERTDIAR LLDMDGIIVE KQRRLATLLG 
LQAPPTRIGL INDMVRFNVL QYVVPEVKDL YNWLEVEFNP LKLCERVTKV LNWVREQPEK 
EPELQQYVPQ LQNNTILRLL QQVSQIYQSI EFSRLTSLVP FVDAFQLERA IVDAARHCDL 
QVRIDHTSRT LSFGSDLNYA TREDAPIGPH LQSMPSEQIR NQLTAMSSVL AKALEVIKPA 
HILQEKEEQH QLAVTAYLKN SRKEHQRILA RRQTIEERKE RLESLNIQRE KEELEQREAE 
LQKVRKAEEE RLRQEAKERE KERILQEHEQ IKKKTVRERL EQIKKTELGA KAFKDIDIED 
LEELDPDFIM AKQVEQLEKE KKELQERLKN QEKKIDYFER AKRLEEIPLI KSAYEEQRIK 
DMDLWEQQEE ERITTMQLER EKALEHKNRM SRMLEDRDLF VMRLKAARQS VYEEKLKQFE 
ERLAEERHNR LEERKRQRKE ERRITYYREK EEEEQRRAEE QMLKEREERE RAERAKREEE 
LREYQERVKK LEEVERKKRQ RELEIEERER RREEERRLGD SSLSRKDSRW GDRDSEGTWR 
KGPEADSEWR RGPPEKEWRR GEGRDEDRSH RRDEERPRRL GDDEDREPSL RPDDDRVPRR 
GMDDDRGPRR GPEEDRFSRR GADDDRPSWR NTDDDRPPRR IADEDRGNWR HADDDRPPRR 
GLDEDRGSWR TADEDRGPRR GMDDDRGPRR GGADDERSSW RNADDDRGPR RGLDDDRGPR 
RGMDDDRGPR RGMDDDRGPR RGMDDDRGPR RGLDDDRGPW RNADDDRIPR RGAEDDRGPW 
RNMDDDRLSR RADDDRFPRR GDDSRPGPWR PLVKPGGWRE KEKAREESWG PPRESRPSEE 
REWDREKERD RDNQDREEND KDPERERDRE RDVDREDRFR RPRDEGGWRR GPAEESSSWR 
DSSRRDDRDR DDRRRERDDR RDLRERRDLR DDRDRRGPPL RSEREEVSSW RRADDRKDDR 
VEERDPPRRV PPPALSRDRE RDRDREREGE KEKASWRAEK DRESLRRTKN ETDEDGWTTV 
RR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.