Details for: MPDZ

Gene ID: 8777

Symbol: MPDZ

Ensembl ID: ENSG00000107186

Description: multiple PDZ domain crumbs cell polarity complex component

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 563.9196
    Cell Significance Index: -87.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 345.0120
    Cell Significance Index: -87.5100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 180.8005
    Cell Significance Index: -85.3600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 171.2339
    Cell Significance Index: -69.5700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 73.0144
    Cell Significance Index: -69.7100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 71.1583
    Cell Significance Index: -87.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 22.2260
    Cell Significance Index: -87.7100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 18.2721
    Cell Significance Index: -39.9900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.8116
    Cell Significance Index: 157.7800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.6117
    Cell Significance Index: 936.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5646
    Cell Significance Index: 514.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.0249
    Cell Significance Index: 155.3900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.8000
    Cell Significance Index: 121.0300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.3025
    Cell Significance Index: 33.4800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2618
    Cell Significance Index: 250.4100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.2132
    Cell Significance Index: 74.5700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.9484
    Cell Significance Index: 13.6400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.9279
    Cell Significance Index: 18.1100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8599
    Cell Significance Index: 594.7200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.7827
    Cell Significance Index: 18.7700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7386
    Cell Significance Index: 1390.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4778
    Cell Significance Index: 24.8900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2810
    Cell Significance Index: 178.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2084
    Cell Significance Index: 94.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1730
    Cell Significance Index: 318.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1649
    Cell Significance Index: 29.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1554
    Cell Significance Index: 239.2400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0996
    Cell Significance Index: 54.4100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0394
    Cell Significance Index: 35.5800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0371
    Cell Significance Index: 50.5000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0298
    Cell Significance Index: 0.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0228
    Cell Significance Index: 2.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0184
    Cell Significance Index: -3.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0224
    Cell Significance Index: -0.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0531
    Cell Significance Index: -23.4800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0666
    Cell Significance Index: -48.8200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0835
    Cell Significance Index: -10.7100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0861
    Cell Significance Index: -2.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1156
    Cell Significance Index: -85.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1174
    Cell Significance Index: -88.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1569
    Cell Significance Index: -97.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1592
    Cell Significance Index: -89.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2480
    Cell Significance Index: -34.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2610
    Cell Significance Index: -75.1100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2856
    Cell Significance Index: -41.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3586
    Cell Significance Index: -58.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3658
    Cell Significance Index: -42.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3938
    Cell Significance Index: -24.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4209
    Cell Significance Index: -43.8300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4389
    Cell Significance Index: -6.4800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4659
    Cell Significance Index: -98.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5070
    Cell Significance Index: -86.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5622
    Cell Significance Index: -72.6300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5635
    Cell Significance Index: -21.3400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5732
    Cell Significance Index: -28.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.5842
    Cell Significance Index: -57.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.6258
    Cell Significance Index: -68.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6491
    Cell Significance Index: -66.3100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6559
    Cell Significance Index: -11.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7383
    Cell Significance Index: -84.5900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7795
    Cell Significance Index: -47.7900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.8256
    Cell Significance Index: -37.4200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.8264
    Cell Significance Index: -13.9200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.8424
    Cell Significance Index: -29.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9336
    Cell Significance Index: -73.9400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.9345
    Cell Significance Index: -66.0900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.9391
    Cell Significance Index: -44.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.9799
    Cell Significance Index: -43.3500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.9965
    Cell Significance Index: -74.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.0149
    Cell Significance Index: -70.1900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.1820
    Cell Significance Index: -55.1100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.1960
    Cell Significance Index: -71.8000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.2273
    Cell Significance Index: -34.3000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.3564
    Cell Significance Index: -70.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.3609
    Cell Significance Index: -71.4500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -1.5518
    Cell Significance Index: -22.0500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.6016
    Cell Significance Index: -23.6400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.6817
    Cell Significance Index: -24.1500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.7031
    Cell Significance Index: -49.0700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.7230
    Cell Significance Index: -36.8300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.7898
    Cell Significance Index: -57.3300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.8671
    Cell Significance Index: -61.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.9094
    Cell Significance Index: -66.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.9527
    Cell Significance Index: -62.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.9873
    Cell Significance Index: -28.4600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -2.0669
    Cell Significance Index: -40.8700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.0788
    Cell Significance Index: -44.1200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.1050
    Cell Significance Index: -52.6200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -2.1234
    Cell Significance Index: -51.8100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -2.1628
    Cell Significance Index: -26.9700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -2.1643
    Cell Significance Index: -62.0400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.1729
    Cell Significance Index: -76.1200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -2.2320
    Cell Significance Index: -28.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -2.3381
    Cell Significance Index: -61.4800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -2.3554
    Cell Significance Index: -39.4200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.3686
    Cell Significance Index: -86.9500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -2.3962
    Cell Significance Index: -51.7700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -2.4141
    Cell Significance Index: -104.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -2.4322
    Cell Significance Index: -66.2000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -2.4766
    Cell Significance Index: -16.7800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MPDZ is a single-gene locus (ENSG00000107186) that encodes a protein consisting of multiple PDZ (PSD-95/Discs Large/ZO-1) domains. The PDZ domains are essential for recognizing and binding to specific sequences in other proteins, thereby regulating protein-protein interactions and cellular processes. The MPDZ protein is primarily expressed in pigmented epithelial cells, GABAergic cortical interneurons, ciliary muscle cells, corneal endothelial cells, vascular leptomeningeal cells, and anterior lens cells. The protein's expression pattern suggests its involvement in maintaining cell polarity and regulating cellular communication in these tissues. **Pathways and Functions:** MPDZ is involved in various signaling pathways, including: 1. **Apical plasma membrane organization**: MPDZ regulates the structure and function of the apical plasma membrane by interacting with other proteins, such as crumbs and occludin, to maintain cell polarity and tight junction assembly. 2. **Tight junction assembly**: MPDZ plays a crucial role in regulating the formation and maintenance of tight junctions, which are essential for maintaining cellular polarity and controlling the passage of molecules across the plasma membrane. 3. **Cell signaling**: MPDZ interacts with other proteins to regulate cell signaling pathways, including those involved in cell migration, differentiation, and survival. 4. **Protein binding**: MPDZ's PDZ domains recognize and bind to specific sequences in other proteins, regulating protein-protein interactions and cellular processes. **Clinical Significance:** Dysregulation of MPDZ has been implicated in various disease states, including: 1. **Neurological disorders**: Mutations in MPDZ have been associated with neurological disorders, such as epilepsy and schizophrenia, which are characterized by abnormal cell polarity and tight junction assembly. 2. **Eye diseases**: MPDZ has been implicated in eye diseases, such as corneal endothelial dysfunction and anterior lens opacification, which are characterized by abnormal cell polarity and tight junction assembly. 3. **Cancer**: MPDZ's role in regulating cell signaling and protein-protein interactions makes it a potential target for cancer therapy, particularly in cancers characterized by abnormal cell polarity and tight junction assembly. In conclusion, MPDZ is a crucial regulator of cell polarity and tight junction assembly, with implications for various cellular processes and disease states. Further research is necessary to fully understand the mechanisms by which MPDZ regulates cellular functions and to explore its potential as a therapeutic target in various disease states.

Genular Protein ID: 3506196214

Symbol: MPDZ_HUMAN

Name: Multiple PDZ domain protein

UniProtKB Accession Codes:

O75970 A6NLC2 B2RTS3 B7ZMI4 O43798 Q4LE30 Q5CZ80 Q5JTX3 Q5JTX6 Q5JTX7 Q5JUC3 Q5JUC4 Q5VZ62 Q8N790

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 11 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 11 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 9537516

Title: Cloning and characterization of MUPP1, a novel PDZ domain protein.

PubMed ID: 9537516

DOI: 10.1016/s0014-5793(98)00141-0

PubMed ID: 11000240

Title: Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins.

PubMed ID: 11000240

DOI: 10.1128/jvi.74.20.9680-9693.2000

PubMed ID: 11150294

Title: Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1.

PubMed ID: 11150294

DOI: 10.1074/jbc.m008089200

PubMed ID: 11802782

Title: Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.

PubMed ID: 11802782

DOI: 10.1042/0264-6021:3610525

PubMed ID: 15364909

Title: The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.

PubMed ID: 15364909

DOI: 10.1074/jbc.m409061200

PubMed ID: 15316081

Title: Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.

PubMed ID: 15316081

DOI: 10.1242/jcs.01301

PubMed ID: 15312654

Title: SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation.

PubMed ID: 15312654

DOI: 10.1016/j.neuron.2004.08.003

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23240096

Title: Mutation in MPDZ causes severe congenital hydrocephalus.

PubMed ID: 23240096

DOI: 10.1136/jmedgenet-2012-101294

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28556411

Title: The genetic landscape of familial congenital hydrocephalus.

PubMed ID: 28556411

DOI: 10.1002/ana.24964

PubMed ID: 17384233

Title: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.

PubMed ID: 17384233

DOI: 10.1110/ps.062657507

Sequence Information:

  • Length: 2070
  • Mass: 221618
  • Checksum: A4D304C20401FD45
  • Sequence:
    • MLEAIDKNRA LHAAERLQTK LRERGDVANE DKLSLLKSVL QSPLFSQILS LQTSVQQLKD 
QVNIATSATS NIEYAHVPHL SPAVIPTLQN ESFLLSPNNG NLEALTGPGI PHINGKPACD 
EFDQLIKNMA QGRHVEVFEL LKPPSGGLGF SVVGLRSENR GELGIFVQEI QEGSVAHRDG 
RLKETDQILA INGQALDQTI THQQAISILQ KAKDTVQLVI ARGSLPQLVS PIVSRSPSAA 
STISAHSNPV HWQHMETIEL VNDGSGLGFG IIGGKATGVI VKTILPGGVA DQHGRLCSGD 
HILKIGDTDL AGMSSEQVAQ VLRQCGNRVK LMIARGAIEE RTAPTALGIT LSSSPTSTPE 
LRVDASTQKG EESETFDVEL TKNVQGLGIT IAGYIGDKKL EPSGIFVKSI TKSSAVEHDG 
RIQIGDQIIA VDGTNLQGFT NQQAVEVLRH TGQTVLLTLM RRGMKQEAEL MSREDVTKDA 
DLSPVNASII KENYEKDEDF LSSTRNTNIL PTEEEGYPLL SAEIEEIEDA QKQEAALLTK 
WQRIMGINYE IVVAHVSKFS ENSGLGISLE ATVGHHFIRS VLPEGPVGHS GKLFSGDELL 
EVNGITLLGE NHQDVVNILK ELPIEVTMVC CRRTVPPTTQ SELDSLDLCD IELTEKPHVD 
LGEFIGSSET EDPVLAMTDA GQSTEEVQAP LAMWEAGIQH IELEKGSKGL GFSILDYQDP 
IDPASTVIII RSLVPGGIAE KDGRLLPGDR LMFVNDVNLE NSSLEEAVEA LKGAPSGTVR 
IGVAKPLPLS PEEGYVSAKE DSFLYPPHSC EEAGLADKPL FRADLALVGT NDADLVDEST 
FESPYSPEND SIYSTQASIL SLHGSSCGDG LNYGSSLPSS PPKDVIENSC DPVLDLHMSL 
EELYTQNLLQ RQDENTPSVD ISMGPASGFT INDYTPANAI EQQYECENTI VWTESHLPSE 
VISSAELPSV LPDSAGKGSE YLLEQSSLAC NAECVMLQNV SKESFERTIN IAKGNSSLGM 
TVSANKDGLG MIVRSIIHGG AISRDGRIAI GDCILSINEE STISVTNAQA RAMLRRHSLI 
GPDIKITYVP AEHLEEFKIS LGQQSGRVMA LDIFSSYTGR DIPELPEREE GEGEESELQN 
TAYSNWNQPR RVELWREPSK SLGISIVGGR GMGSRLSNGE VMRGIFIKHV LEDSPAGKNG 
TLKPGDRIVE VDGMDLRDAS HEQAVEAIRK AGNPVVFMVQ SIINRPRKSP LPSLLHNLYP 
KYNFSSTNPF ADSLQINADK APSQSESEPE KAPLCSVPPP PPSAFAEMGS DHTQSSASKI 
SQDVDKEDEF GYSWKNIRER YGTLTGELHM IELEKGHSGL GLSLAGNKDR SRMSVFIVGI 
DPNGAAGKDG RLQIADELLE INGQILYGRS HQNASSIIKC APSKVKIIFI RNKDAVNQMA 
VCPGNAVEPL PSNSENLQNK ETEPTVTTSD AAVDLSSFKN VQHLELPKDQ GGLGIAISEE 
DTLSGVIIKS LTEHGVAATD GRLKVGDQIL AVDDEIVVGY PIEKFISLLK TAKMTVKLTI 
HAENPDSQAV PSAAGAASGE KKNSSQSLMV PQSGSPEPES IRNTSRSSTP AIFASDPATC 
PIIPGCETTI EISKGRTGLG LSIVGGSDTL LGAIIIHEVY EEGAACKDGR LWAGDQILEV 
NGIDLRKATH DEAINVLRQT PQRVRLTLYR DEAPYKEEEV CDTLTIELQK KPGKGLGLSI 
VGKRNDTGVF VSDIVKGGIA DADGRLMQGD QILMVNGEDV RNATQEAVAA LLKCSLGTVT 
LEVGRIKAGP FHSERRPSQS SQVSEGSLSS FTFPLSGSST SESLESSSKK NALASEIQGL 
RTVEMKKGPT DSLGISIAGG VGSPLGDVPI FIAMMHPTGV AAQTQKLRVG DRIVTICGTS 
TEGMTHTQAV NLLKNASGSI EMQVVAGGDV SVVTGHQQEP ASSSLSFTGL TSSSIFQDDL 
GPPQCKSITL ERGPDGLGFS IVGGYGSPHG DLPIYVKTVF AKGAASEDGR LKRGDQIIAV 
NGQSLEGVTH EEAVAILKRT KGTVTLMVLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.