Details for: DACH1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 5.99
Marker Score: 6,355 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 5.1
Marker Score: 9,803 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 4.29
Marker Score: 2,063 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 4.2
Marker Score: 2,440 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 4.12
Marker Score: 2,309 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 3.67
Marker Score: 7,587 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 3.24
Marker Score: 2,590 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 3.11
Marker Score: 909 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 3.02
Marker Score: 958 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 2.77
Marker Score: 3,915 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 2.75
Marker Score: 936 - Cell Name: podocyte (CL0000653)
Fold Change: 2.71
Marker Score: 1,000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.65
Marker Score: 11,111 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.39
Marker Score: 1,841 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.2
Marker Score: 1,529 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 2.14
Marker Score: 555 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.96
Marker Score: 1,172 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.94
Marker Score: 4,258 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.94
Marker Score: 612 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.85
Marker Score: 113,955 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.84
Marker Score: 16,160 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.8
Marker Score: 493 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.79
Marker Score: 802 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.79
Marker Score: 993 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.78
Marker Score: 1,580 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.77
Marker Score: 1,689 - Cell Name: contractile cell (CL0000183)
Fold Change: 1.74
Marker Score: 942 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.62
Marker Score: 677 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.59
Marker Score: 505 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.54
Marker Score: 13,231 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.48
Marker Score: 3,012 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.48
Marker Score: 3,090 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,687 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.46
Marker Score: 1,683 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 1.44
Marker Score: 2,380 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.43
Marker Score: 955 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.41
Marker Score: 13,395 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.36
Marker Score: 819 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.32
Marker Score: 13,294 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 1.3
Marker Score: 332 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.24
Marker Score: 4,407 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.15
Marker Score: 3,076 - Cell Name: Unknown (CL0002371)
Fold Change: 1.09
Marker Score: 1,156 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.07
Marker Score: 411 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.04
Marker Score: 1,774 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,766 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.03
Marker Score: 2,064 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.99
Marker Score: 318 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,405 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.97
Marker Score: 501 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 455 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.96
Marker Score: 907 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.96
Marker Score: 6,356 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.95
Marker Score: 2,599 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.95
Marker Score: 1,324 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,410 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.94
Marker Score: 494 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.93
Marker Score: 14,523 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.91
Marker Score: 1,104 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,736 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.91
Marker Score: 5,479 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.89
Marker Score: 2,249 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 319 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5,049 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.82
Marker Score: 1,612 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.82
Marker Score: 192 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.81
Marker Score: 1,314 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.81
Marker Score: 1,115 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.8
Marker Score: 758 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.79
Marker Score: 247 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.78
Marker Score: 373 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.78
Marker Score: 314 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 592 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.77
Marker Score: 309 - Cell Name: brush cell (CL0002204)
Fold Change: 0.76
Marker Score: 698 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.76
Marker Score: 824 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.76
Marker Score: 1,793 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.76
Marker Score: 213 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.74
Marker Score: 189 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.73
Marker Score: 297 - Cell Name: granule cell (CL0000120)
Fold Change: 0.73
Marker Score: 5,487 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.72
Marker Score: 266 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.71
Marker Score: 472 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 0.71
Marker Score: 608 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.7
Marker Score: 179 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2,947 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.69
Marker Score: 735 - Cell Name: germ cell (CL0000586)
Fold Change: 0.69
Marker Score: 1,213 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.68
Marker Score: 258 - Cell Name: neuron (CL0000540)
Fold Change: 0.68
Marker Score: 2,765 - Cell Name: macroglial cell (CL0000126)
Fold Change: 0.66
Marker Score: 1,508 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.65
Marker Score: 381 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.64
Marker Score: 234 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.64
Marker Score: 239 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 0.63
Marker Score: 914 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.61
Marker Score: 159 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.6
Marker Score: 311 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 0.58
Marker Score: 621
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 282247221
Symbol: DACH1_HUMAN
Name: Dachshund homolog 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10502110
Title: Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene.
PubMed ID: 10502110
PubMed ID: 11543628
Title: Dach: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homolog.
PubMed ID: 11543628
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 9651501
Title: Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb.
PubMed ID: 9651501
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14525983
Title: DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
PubMed ID: 14525983
PubMed ID: 12057194
Title: Structure of the retinal determination protein dachshund reveals a DNA binding motif.
PubMed ID: 12057194
Sequence Information:
- Length: 758
- Mass: 78562
- Checksum: DFB5054D7EC5FF11
- Sequence:
MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS GPTLFRPEPI ASAAAAAATV TSTGGGGGGG GSGGGGGSSG NGGGGGGGGG GSNCNPNLAA ASNGSGGGGG GISAGGGVAS STPINASTGS SSSSSSSSSS SSSSSSSSSS SSSCGPLPGK PVYSTPSPVE NTPQNNECKM VDLRGAKVAS FTVEGCELIC LPQAFDLFLK HLVGGLHTVY TKLKRLEITP VVCNVEQVRI LRGLGAIQPG VNRCKLISRK DFETLYNDCT NASSRPGRPP KRTQSVTSPE NSHIMPHSVP GLMSPGIIPP TGLTAAAAAA AAATNAAIAE AMKVKKIKLE AMSNYHASNN QHGADSENGD MNSSVGSSDG SWDKETLPSS PSQGPQASIT HPRMPGARSL PLSHPLNHLQ QSHLLPNGLE LPFMMMPHPL IPVSLPPASV TMAMSQMNHL STIANMAAAA QVQSPPSRVE TSVIKERVPD SPSPAPSLEE GRRPGSHPSS HRSSSVSSSP ARTESSSDRI PVHQNGLSMN QMLMGLSPNV LPGPKEGDLA GHDMGHESKR MHIEKDETPL STPTARDSLD KLSLTGHGQP LPPGFPSPFL FPDGLSSIET LLTNIQGLLK VAIDNARAQE KQVQLEKTEL KMDFLREREL RETLEKQLAM EQKNRAIVQK RLKKEKKAKR KLQEALEFET KRREQAEQTL KQAASTDSLR VLNDSLTPEI EADRSGGRTD AERTIQDGRL YLKTTVMY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.