Details for: EGR3

Gene ID: 1960

Symbol: EGR3

Ensembl ID: ENSG00000179388

Description: early growth response 3

Associated with

  • Ngf-stimulated transcription
    (R-HSA-9031628)
  • Nuclear events (kinase and transcription factor activation)
    (R-HSA-198725)
  • Signaling by ntrk1 (trka)
    (R-HSA-187037)
  • Signaling by ntrks
    (R-HSA-166520)
  • Signaling by receptor tyrosine kinases
    (R-HSA-9006934)
  • Signal transduction
    (R-HSA-162582)
  • Cell migration involved in sprouting angiogenesis
    (GO:0002042)
  • Cellular response to fibroblast growth factor stimulus
    (GO:0044344)
  • Cellular response to vascular endothelial growth factor stimulus
    (GO:0035924)
  • Chromatin
    (GO:0000785)
  • Circadian rhythm
    (GO:0007623)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Endothelial cell chemotaxis
    (GO:0035767)
  • Metal ion binding
    (GO:0046872)
  • Muscle organ development
    (GO:0007517)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Neuromuscular synaptic transmission
    (GO:0007274)
  • Nucleoplasm
    (GO:0005654)
  • Peripheral nervous system development
    (GO:0007422)
  • Positive regulation of endothelial cell proliferation
    (GO:0001938)
  • Positive regulation of t cell differentiation in thymus
    (GO:0033089)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of gamma-delta t cell differentiation
    (GO:0045586)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Synapse
    (GO:0045202)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 114.3719
    Cell Significance Index: -17.7900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 69.1916
    Cell Significance Index: -17.5500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 24.5558
    Cell Significance Index: -16.4800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.4125
    Cell Significance Index: -17.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.5070
    Cell Significance Index: -17.7900
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 3.0530
    Cell Significance Index: 3.9500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.3480
    Cell Significance Index: 157.0900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9467
    Cell Significance Index: 49.1800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8467
    Cell Significance Index: 59.8800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7910
    Cell Significance Index: 349.7300
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.7702
    Cell Significance Index: 6.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7123
    Cell Significance Index: 87.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7046
    Cell Significance Index: 19.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6124
    Cell Significance Index: 116.5400
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.5390
    Cell Significance Index: 7.5600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5072
    Cell Significance Index: 22.9900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5027
    Cell Significance Index: 11.6200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.4974
    Cell Significance Index: 310.6200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4783
    Cell Significance Index: 13.7100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4439
    Cell Significance Index: 12.7900
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.4202
    Cell Significance Index: 5.8300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.4149
    Cell Significance Index: 10.9100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4050
    Cell Significance Index: 81.2400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2851
    Cell Significance Index: 28.2000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2703
    Cell Significance Index: 244.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2506
    Cell Significance Index: 136.8600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2351
    Cell Significance Index: 8.2600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2327
    Cell Significance Index: 3.6000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1940
    Cell Significance Index: 34.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1768
    Cell Significance Index: 8.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1602
    Cell Significance Index: 10.7700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1563
    Cell Significance Index: 25.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1324
    Cell Significance Index: 17.1100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1314
    Cell Significance Index: 14.2900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1071
    Cell Significance Index: 2.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1017
    Cell Significance Index: 4.7400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0995
    Cell Significance Index: 13.6700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0943
    Cell Significance Index: 2.6900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0911
    Cell Significance Index: 11.6800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0843
    Cell Significance Index: 9.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0710
    Cell Significance Index: 4.2600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0704
    Cell Significance Index: 0.9600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0239
    Cell Significance Index: 1.6600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0056
    Cell Significance Index: -4.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0061
    Cell Significance Index: -3.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0089
    Cell Significance Index: -16.7400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0127
    Cell Significance Index: -9.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0204
    Cell Significance Index: -12.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0209
    Cell Significance Index: -15.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0249
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0292
    Cell Significance Index: -6.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0310
    Cell Significance Index: -11.1200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0354
    Cell Significance Index: -16.0900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0417
    Cell Significance Index: -11.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0471
    Cell Significance Index: -8.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0547
    Cell Significance Index: -6.2700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0573
    Cell Significance Index: -8.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0581
    Cell Significance Index: -1.8600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0713
    Cell Significance Index: -0.8100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0715
    Cell Significance Index: -5.3300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0728
    Cell Significance Index: -1.2000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0744
    Cell Significance Index: -8.7800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0779
    Cell Significance Index: -15.4500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0834
    Cell Significance Index: -1.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1042
    Cell Significance Index: -2.6100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1086
    Cell Significance Index: -3.2000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1286
    Cell Significance Index: -4.8700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1287
    Cell Significance Index: -13.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1367
    Cell Significance Index: -8.3800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1440
    Cell Significance Index: -2.1700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.1508
    Cell Significance Index: -2.0100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1524
    Cell Significance Index: -4.2600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1552
    Cell Significance Index: -6.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1686
    Cell Significance Index: -17.5600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1737
    Cell Significance Index: -3.0700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1882
    Cell Significance Index: -14.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1976
    Cell Significance Index: -12.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2085
    Cell Significance Index: -16.0000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2315
    Cell Significance Index: -4.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2331
    Cell Significance Index: -12.2400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2536
    Cell Significance Index: -9.3100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2610
    Cell Significance Index: -16.0400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2631
    Cell Significance Index: -13.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2686
    Cell Significance Index: -15.0700
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.2759
    Cell Significance Index: -2.8800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3173
    Cell Significance Index: -11.0300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.3341
    Cell Significance Index: -5.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3428
    Cell Significance Index: -9.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3443
    Cell Significance Index: -9.2100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3597
    Cell Significance Index: -12.6000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3627
    Cell Significance Index: -9.6900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3655
    Cell Significance Index: -11.6400
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.4144
    Cell Significance Index: -5.7300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4155
    Cell Significance Index: -7.6800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4349
    Cell Significance Index: -14.2400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4419
    Cell Significance Index: -9.2500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5199
    Cell Significance Index: -15.2700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.5244
    Cell Significance Index: -7.3600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5415
    Cell Significance Index: -13.9200
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.5434
    Cell Significance Index: -7.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** EGR3 is a member of the early growth response (EGR) family of transcription factors, which are known for their ability to regulate gene expression in response to various cellular signals. The EGR3 protein is a DNA-binding transcription activator that regulates the expression of target genes involved in cell proliferation, differentiation, and survival. It is also a potent transcriptional co-repressor, capable of inhibiting the expression of certain genes. EGR3 is highly conserved across species, with high sequence identity to its mouse and rat counterparts, suggesting its conserved function across species. **Pathways and Functions** EGR3 is involved in a wide range of cellular processes, including: 1. **Angiogenesis**: EGR3 regulates the expression of genes involved in endothelial cell migration, proliferation, and differentiation, making it a key player in the formation of new blood vessels. 2. **Nervous system development**: EGR3 is essential for the development of the nervous system, particularly in the formation of the cerebral cortex and the regulation of neuronal migration and differentiation. 3. **Immune response**: EGR3 regulates the expression of genes involved in immune response, including the differentiation of T cells and the regulation of cytokine production. 4. **Cell migration**: EGR3 is involved in the regulation of cell migration, including the migration of endothelial cells, neurons, and immune cells. 5. **Apoptosis**: EGR3 has been shown to regulate the expression of anti-apoptotic genes, preventing excessive cell death. **Clinical Significance** The dysregulation of EGR3 has been implicated in various diseases, including: 1. **Cancer**: Overexpression of EGR3 has been observed in several types of cancer, including breast, lung, and colon cancer, where it promotes tumor growth and metastasis. 2. **Neurodegenerative diseases**: EGR3 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where it regulates the expression of genes involved in neuronal survival and differentiation. 3. **Cardiovascular disease**: EGR3 has been shown to regulate the expression of genes involved in cardiovascular disease, including the regulation of endothelial cell function and the promotion of atherosclerosis. 4. **Immune disorders**: EGR3 has been implicated in the pathogenesis of immune disorders, such as autoimmune diseases, where it regulates the expression of genes involved in immune response and tolerance. In conclusion, EGR3 is a critical transcription factor that regulates various cellular processes, including cell migration, proliferation, and differentiation. Its dysregulation has been implicated in various diseases, making it a promising target for therapeutic intervention. Further studies are needed to fully elucidate the functions of EGR3 and its role in disease pathogenesis.

Genular Protein ID: 1966248341

Symbol: EGR3_HUMAN

Name: Early growth response protein 3

UniProtKB Accession Codes:

Q06889 A8K8U9 B4DHJ5 E7EW38 Q2M3W2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 ExpressionAtlas 1 GO 22 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8443122

Title: Expression of PILOT, a putative transcription factor, requires two signals and is cyclosporin A sensitive in T cells.

PubMed ID: 8443122

DOI: 10.1093/intimm/5.1.63

PubMed ID: 1906159

Title: EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

PubMed ID: 1906159

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 387
  • Mass: 42613
  • Checksum: 77FAF7D5A278C68E
  • Sequence:
    • MTGKLAEKLP VTMSSLLNQL PDNLYPEEIP SALNLFSGSS DSVVHYNQMA TENVMDIGLT 
NEKPNPELSY SGSFQPAPGN KTVTYLGKFA FDSPSNWCQD NIISLMSAGI LGVPPASGAL 
STQTSTASMV QPPQGDVEAM YPALPPYSNC GDLYSEPVSF HDPQGNPGLA YSPQDYQSAK 
PALDSNLFPM IPDYNLYHHP NDMGSIPEHK PFQGMDPIRV NPPPITPLET IKAFKDKQIH 
PGFGSLPQPP LTLKPIRPRK YPNRPSKTPL HERPHACPAE GCDRRFSRSD ELTRHLRIHT 
GHKPFQCRIC MRSFSRSDHL TTHIRTHTGE KPFACEFCGR KFARSDERKR HAKIHLKQKE 
KKAEKGGAPS ASSAPPVSLA PVVTTCA

Genular Protein ID: 3902035284

Symbol: B4DH80_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DH80

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 Pfam 2 RefSeq 2 RuleBase 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 333
  • Mass: 36736
  • Checksum: 846A3E579E71B66C
  • Sequence:
    • MDIGLTNEKP NPELSYSGSF QPAPGNKTVT YLGKFAFDSP SNWCQDNIIS LMSAGILGVP 
PASGALSTQT STASMVQPPQ GDVEAMYPAL PPYSNCGDLY SEPVSFHDPQ GNPGLAYSPQ 
DYQSAKPALD SNLFPMIPDY NLYHHPNDMG SIPEHKPFQG MDPIRVNPPP ITPLETIKAF 
KDKQIHPGFG SLPQPPLTLK PIRPRKYPNR PSKTPLHERP HACPAEGCDR RFSRSDELTR 
HLRIHTGHKP FQCRICMRSF SRSDHLTTHI RTHTGEKPFA CEFCGRKFAR SDERKRHAKI 
HLKQKEKKAE KGGAPSASSA PPVSLAPVVT TCA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.