Details for: EIF4A1

Gene ID: 1973

Symbol: EIF4A1

Ensembl ID: ENSG00000161960

Description: eukaryotic translation initiation factor 4A1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 593.2037
    Cell Significance Index: -92.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 299.5544
    Cell Significance Index: -75.9800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 227.7374
    Cell Significance Index: -107.5200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 220.1315
    Cell Significance Index: -89.4300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 202.5525
    Cell Significance Index: -104.1900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 160.4567
    Cell Significance Index: -107.6700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 96.3715
    Cell Significance Index: -92.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 80.9275
    Cell Significance Index: -99.7800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 38.5910
    Cell Significance Index: -103.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 25.9044
    Cell Significance Index: -102.2200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 21.0910
    Cell Significance Index: -64.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 19.1036
    Cell Significance Index: -41.8100
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 11.3476
    Cell Significance Index: 97.5100
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 10.9915
    Cell Significance Index: 78.9400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 10.4948
    Cell Significance Index: 300.8400
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 9.8386
    Cell Significance Index: 29.2600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 6.3129
    Cell Significance Index: 145.8500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 6.0663
    Cell Significance Index: 107.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 5.9309
    Cell Significance Index: 760.3100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 5.8004
    Cell Significance Index: 170.3500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 4.7378
    Cell Significance Index: 222.6700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 4.4585
    Cell Significance Index: 50.6500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.2324
    Cell Significance Index: 38.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 4.0800
    Cell Significance Index: 501.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.7702
    Cell Significance Index: 487.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.6380
    Cell Significance Index: 655.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.5963
    Cell Significance Index: 268.0300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.4961
    Cell Significance Index: 182.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.3976
    Cell Significance Index: 466.5900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 3.1784
    Cell Significance Index: 66.5300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 3.1295
    Cell Significance Index: 108.7500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.5038
    Cell Significance Index: 27.2200
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 2.3174
    Cell Significance Index: 10.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.3078
    Cell Significance Index: 163.2200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.2463
    Cell Significance Index: 1226.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.0416
    Cell Significance Index: 902.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.8755
    Cell Significance Index: 51.0500
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.7345
    Cell Significance Index: 10.1900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.7118
    Cell Significance Index: 10.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.5995
    Cell Significance Index: 103.1900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.5919
    Cell Significance Index: 12.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3543
    Cell Significance Index: 147.3100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.3177
    Cell Significance Index: 34.6500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.2325
    Cell Significance Index: 32.9100
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 0.8145
    Cell Significance Index: 4.6700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7796
    Cell Significance Index: 16.8900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7778
    Cell Significance Index: 156.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5991
    Cell Significance Index: 540.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5628
    Cell Significance Index: 29.5500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5102
    Cell Significance Index: 101.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4778
    Cell Significance Index: 171.3800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4621
    Cell Significance Index: 25.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3710
    Cell Significance Index: 10.6900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3578
    Cell Significance Index: 42.1900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1713
    Cell Significance Index: 32.5900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.1407
    Cell Significance Index: 0.8500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1249
    Cell Significance Index: 2.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1107
    Cell Significance Index: 83.7800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0461
    Cell Significance Index: 4.7100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0330
    Cell Significance Index: -1.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0443
    Cell Significance Index: -7.2100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0552
    Cell Significance Index: -103.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0628
    Cell Significance Index: -115.7900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0753
    Cell Significance Index: -115.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0795
    Cell Significance Index: -58.3200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0852
    Cell Significance Index: -115.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1022
    Cell Significance Index: -75.7300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.1041
    Cell Significance Index: -72.0100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1328
    Cell Significance Index: -8.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1562
    Cell Significance Index: -99.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1635
    Cell Significance Index: -92.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1810
    Cell Significance Index: -113.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2262
    Cell Significance Index: -102.6800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.2388
    Cell Significance Index: -23.6300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2636
    Cell Significance Index: -45.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2923
    Cell Significance Index: -84.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3500
    Cell Significance Index: -9.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3572
    Cell Significance Index: -24.7000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4251
    Cell Significance Index: -17.4200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.5030
    Cell Significance Index: -22.8000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5173
    Cell Significance Index: -26.8700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5228
    Cell Significance Index: -110.1200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5973
    Cell Significance Index: -69.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.6965
    Cell Significance Index: -101.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7493
    Cell Significance Index: -85.8500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8414
    Cell Significance Index: -64.5700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8802
    Cell Significance Index: -41.0400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.9295
    Cell Significance Index: -17.1800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.9334
    Cell Significance Index: -25.0100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.9471
    Cell Significance Index: -24.2000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.1482
    Cell Significance Index: -90.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.1926
    Cell Significance Index: -80.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.3461
    Cell Significance Index: -82.5300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.4137
    Cell Significance Index: -49.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.4452
    Cell Significance Index: -8.9800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.4836
    Cell Significance Index: -22.2300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.5380
    Cell Significance Index: -49.2600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5500
    Cell Significance Index: -38.7500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.6012
    Cell Significance Index: -100.9200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.6219
    Cell Significance Index: -71.7400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EIF4A1 is a single-codon-decoding gene that encodes a protein with helicase and ATPase activity. Its primary function is to facilitate the translation initiation process by binding to the mRNA cap and recruiting the 43S ribosomal subunit. This gene is highly conserved across species, suggesting its essential role in eukaryotic translation initiation. EIF4A1 is also involved in various cellular processes, including antiviral mechanisms, cytokine signaling, and protein metabolism. **Pathways and Functions:** EIF4A1 is embedded in multiple signaling pathways, including: 1. **Activation of mRNA upon binding of the cap-binding complex and eIFs**: EIF4A1 plays a crucial role in the recruitment of the 43S ribosomal subunit to the mRNA cap, facilitating the initiation of translation. 2. **Antiviral mechanisms by IFN-stimulated genes**: EIF4A1 is involved in the regulation of antiviral gene expression in response to interferons (IFNs). 3. **ATP binding and hydrolysis activity**: EIF4A1 exhibits ATPase activity, which is essential for its helicase function. 4. **Cap-dependent translation initiation**: EIF4A1 is a key component of the cap-dependent translation initiation pathway, which is responsible for the translation of mRNAs containing the 5' cap. 5. **Cytokine signaling in the immune system**: EIF4A1 is involved in the regulation of cytokine signaling, which is essential for the proper functioning of the immune system. 6. **Deadenylation-dependent mRNA decay**: EIF4A1 is involved in the regulation of mRNA decay, which is essential for the control of gene expression. **Clinical Significance:** EIF4A1 has been implicated in various diseases, including: 1. **Cancer**: EIF4A1 has been found to be overexpressed in several types of cancer, including breast, lung, and colon cancer. 2. **Infectious diseases**: EIF4A1 has been shown to play a role in the regulation of antiviral gene expression in response to IFNs. 3. **Neurological disorders**: EIF4A1 has been implicated in the regulation of protein metabolism and has been found to be associated with neurodegenerative diseases, such as Alzheimer's disease. 4. **Immune system disorders**: EIF4A1 has been found to be involved in the regulation of cytokine signaling and has been implicated in immune system disorders, such as rheumatoid arthritis. In conclusion, EIF4A1 is a multifaceted gene that plays a crucial role in eukaryotic translation initiation and various cellular processes. Its significant expression in various cell types underscores its importance in multiple biological processes. Further research is needed to fully elucidate the functions and clinical significance of EIF4A1.

Genular Protein ID: 2077815853

Symbol: IF4A1_HUMAN

Name: Eukaryotic initiation factor 4A-I

UniProtKB Accession Codes:

P60842 B2R6L8 D3DTP9 J3QLC4 P04765 Q5U018 Q61516

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChEBI 6 ChEMBL 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 2 EMBL 11 EMDB 4 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIR 1 PRIDE 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 2 Rhea 1 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8493113

Title: Nucleotide sequence of human cDNA encoding eukaryotic initiation factor 4AI.

PubMed ID: 8493113

DOI: 10.1093/nar/21.8.2012

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9548260

Title: Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.

PubMed ID: 9548260

DOI: 10.1038/33198

PubMed ID: 11073994

Title: Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes.

PubMed ID: 11073994

DOI: 10.1128/mcb.20.23.8944-8957.2000

PubMed ID: 11408474

Title: Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo.

PubMed ID: 11408474

DOI: 10.1074/jbc.c100284200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15282546

Title: Exportin 7 defines a novel general nuclear export pathway.

PubMed ID: 15282546

DOI: 10.1038/sj.emboj.7600338

PubMed ID: 15715967

Title: Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia.

PubMed ID: 15715967

DOI: 10.1016/j.gene.2004.12.027

PubMed ID: 17284590

Title: Cell stress modulates the function of splicing regulatory protein RBM4 in translation control.

PubMed ID: 17284590

DOI: 10.1073/pnas.0611015104

PubMed ID: 18596238

Title: The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control.

PubMed ID: 18596238

DOI: 10.1091/mbc.e07-12-1264

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20133758

Title: Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1.

PubMed ID: 20133758

DOI: 10.1073/pnas.0914856107

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 19153607

Title: Structural basis for translational inhibition by the tumour suppressor Pdcd4.

PubMed ID: 19153607

DOI: 10.1038/emboj.2008.278

PubMed ID: 19204291

Title: Crystal structure of the eIF4A-PDCD4 complex.

PubMed ID: 19204291

DOI: 10.1073/pnas.0808275106

PubMed ID: 20941364

Title: Comparative structural analysis of human DEAD-box RNA helicases.

PubMed ID: 20941364

DOI: 10.1371/journal.pone.0012791

Sequence Information:

  • Length: 406
  • Mass: 46154
  • Checksum: 6EF89939F3045420
  • Sequence:
    • MSASQDSRSR DNGPDGMEPE GVIESNWNEI VDSFDDMNLS ESLLRGIYAY GFEKPSAIQQ 
RAILPCIKGY DVIAQAQSGT GKTATFAISI LQQIELDLKA TQALVLAPTR ELAQQIQKVV 
MALGDYMGAS CHACIGGTNV RAEVQKLQME APHIIVGTPG RVFDMLNRRY LSPKYIKMFV 
LDEADEMLSR GFKDQIYDIF QKLNSNTQVV LLSATMPSDV LEVTKKFMRD PIRILVKKEE 
LTLEGIRQFY INVEREEWKL DTLCDLYETL TITQAVIFIN TRRKVDWLTE KMHARDFTVS 
AMHGDMDQKE RDVIMREFRS GSSRVLITTD LLARGIDVQQ VSLVINYDLP TNRENYIHRI 
GRGGRFGRKG VAINMVTEED KRTLRDIETF YNTSIEEMPL NVADLI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.