Details for: FKBP5

Gene ID: 2289

Symbol: FKBP5

Ensembl ID: ENSG00000096060

Description: FKBP prolyl isomerase 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 499.0188
    Cell Significance Index: -77.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 287.7268
    Cell Significance Index: -72.9800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 172.7161
    Cell Significance Index: -71.1500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 164.3217
    Cell Significance Index: -77.5800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 158.8403
    Cell Significance Index: -64.5300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 142.0142
    Cell Significance Index: -73.0500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 115.6743
    Cell Significance Index: -77.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 65.4200
    Cell Significance Index: -80.6600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 31.6593
    Cell Significance Index: -97.2400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 27.7394
    Cell Significance Index: -74.3100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 26.2932
    Cell Significance Index: 178.1500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 25.4868
    Cell Significance Index: -55.7800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.6333
    Cell Significance Index: -81.4200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 11.6664
    Cell Significance Index: 196.5200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 9.2084
    Cell Significance Index: 224.6800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 9.1183
    Cell Significance Index: 114.8200
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 8.2435
    Cell Significance Index: 133.0100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 5.2621
    Cell Significance Index: 46.7100
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 4.8815
    Cell Significance Index: 50.5600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 4.7833
    Cell Significance Index: 102.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 4.7591
    Cell Significance Index: 133.0000
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 3.9166
    Cell Significance Index: 8.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.4246
    Cell Significance Index: 262.8000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.9893
    Cell Significance Index: 76.8400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.5434
    Cell Significance Index: 49.6400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.7205
    Cell Significance Index: 111.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.5182
    Cell Significance Index: 37.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4500
    Cell Significance Index: 1309.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.4356
    Cell Significance Index: 156.1500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1086
    Cell Significance Index: 220.0000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.0103
    Cell Significance Index: 15.3700
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.9648
    Cell Significance Index: 4.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.8751
    Cell Significance Index: 555.8100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.8698
    Cell Significance Index: 12.4900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.7121
    Cell Significance Index: 10.5100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.7121
    Cell Significance Index: 47.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6811
    Cell Significance Index: 244.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.6793
    Cell Significance Index: 308.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.6179
    Cell Significance Index: 840.2100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5497
    Cell Significance Index: 1035.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5243
    Cell Significance Index: 15.1100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5130
    Cell Significance Index: 83.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5095
    Cell Significance Index: 102.2000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4817
    Cell Significance Index: 66.1500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4148
    Cell Significance Index: 18.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2940
    Cell Significance Index: 452.6400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.2907
    Cell Significance Index: 30.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2630
    Cell Significance Index: 485.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2208
    Cell Significance Index: 42.0200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1681
    Cell Significance Index: 74.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1570
    Cell Significance Index: 115.1400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1447
    Cell Significance Index: 100.0600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1209
    Cell Significance Index: 3.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1202
    Cell Significance Index: 14.7900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0919
    Cell Significance Index: 3.2300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0467
    Cell Significance Index: 0.6900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0164
    Cell Significance Index: -2.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0312
    Cell Significance Index: -17.0300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0422
    Cell Significance Index: -4.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0448
    Cell Significance Index: -33.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0790
    Cell Significance Index: -49.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0827
    Cell Significance Index: -6.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0904
    Cell Significance Index: -51.0000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0956
    Cell Significance Index: -72.3400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1126
    Cell Significance Index: -11.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1342
    Cell Significance Index: -15.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1653
    Cell Significance Index: -28.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1772
    Cell Significance Index: -22.9000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2084
    Cell Significance Index: -30.2900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2471
    Cell Significance Index: -71.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2495
    Cell Significance Index: -31.9900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2627
    Cell Significance Index: -55.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3514
    Cell Significance Index: -17.7600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3811
    Cell Significance Index: -17.7700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4378
    Cell Significance Index: -34.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4915
    Cell Significance Index: -30.9800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.5215
    Cell Significance Index: -24.5100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5263
    Cell Significance Index: -7.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6001
    Cell Significance Index: -31.2600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.6361
    Cell Significance Index: -44.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6536
    Cell Significance Index: -14.1600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6606
    Cell Significance Index: -76.9900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7079
    Cell Significance Index: -80.8100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.7710
    Cell Significance Index: -12.3700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7901
    Cell Significance Index: -90.5200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8310
    Cell Significance Index: -50.9500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.9265
    Cell Significance Index: -51.9900
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.9532
    Cell Significance Index: -13.3600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.0231
    Cell Significance Index: -18.9100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.1611
    Cell Significance Index: -51.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.2199
    Cell Significance Index: -39.0700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.2270
    Cell Significance Index: -75.4200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.3030
    Cell Significance Index: -68.4100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.3423
    Cell Significance Index: -50.8300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.4413
    Cell Significance Index: -74.8700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.5571
    Cell Significance Index: -45.7300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.6440
    Cell Significance Index: -60.3500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.6845
    Cell Significance Index: -48.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.7094
    Cell Significance Index: -59.4000
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -1.7235
    Cell Significance Index: -22.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FKBP5 is a 32-kDa protein that exhibits peptidyl-prolyl cis-trans isomerase activity, which is essential for the proper folding of proteins. The protein is also a potent inhibitor of the immunosuppressive drug cyclosporin A (CsA), which is used to prevent organ rejection in transplant patients. FKBP5 has been shown to interact with various transcription factors, including NF-κB and CREB, which are involved in the regulation of immune responses and stress response pathways. **Pathways and Functions** FKBP5 is involved in several cellular pathways, including: 1. **Chaperone-mediated protein folding**: FKBP5 is a chaperone protein that assists in the folding of proteins, particularly those with disordered or unfolded structures. 2. **Stress response**: FKBP5 is highly expressed in cells that are exposed to high levels of stress, such as skeletal muscle fibers, cardiac neurons, and microglial cells. It plays a crucial role in the regulation of stress response pathways, including the NF-κB and Hsp70 pathways. 3. **Immune responses**: FKBP5 is expressed in cells that are involved in immune responses, including basal epithelial cells of the prostatic duct and tracheobronchial tree. It interacts with various transcription factors, including NF-κB and CREB, which are involved in the regulation of immune responses. 4. **Transcriptional regulation**: FKBP5 interacts with transcription factors, including Mecp2, which regulates neuronal receptors and channels. **Clinical Significance** FKBP5 has significant clinical implications, particularly in the context of immune regulation and stress response. Some of the key clinical implications of FKBP5 include: 1. **Transplant rejection**: FKBP5 is involved in the regulation of immune responses, and its dysregulation can lead to transplant rejection. 2. **Stress-related disorders**: FKBP5 is highly expressed in cells that are exposed to high levels of stress, and its dysregulation has been implicated in stress-related disorders, including post-traumatic stress disorder (PTSD) and anxiety disorders. 3. **Cancer**: FKBP5 has been shown to interact with various transcription factors, including NF-κB and CREB, which are involved in the regulation of cancer cell growth and survival. 4. **Neurological disorders**: FKBP5 has been implicated in the regulation of neuronal receptors and channels, and its dysregulation has been linked to various neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, FKBP5 is a critical gene that plays a pivotal role in the regulation of cellular responses to stress, immune responses, and protein folding. Its dysregulation has significant clinical implications, particularly in the context of immune regulation and stress response. Further research is needed to fully elucidate the mechanisms by which FKBP5 regulates cellular processes and to explore its therapeutic potential in various diseases.

Genular Protein ID: 3672286074

Symbol: FKBP5_HUMAN

Name: Peptidyl-prolyl cis-trans isomerase FKBP5

UniProtKB Accession Codes:

Q13451 F5H7R1 Q59EB8 Q5TGM6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CPTAC 2 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugCentral 1 EC 1 EMBL 10 EMDB 2 Ensembl 4 EvolutionaryTrace 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 97 PDBsum 97 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 Rhea 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9125197

Title: Tissue distribution and abundance of human FKBP51, an FK506-binding protein that can mediate calcineurin inhibition.

PubMed ID: 9125197

DOI: 10.1006/bbrc.1997.6307

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9001212

Title: Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor.

PubMed ID: 9001212

DOI: 10.1128/mcb.17.2.594

PubMed ID: 7693698

Title: FKBP54, a novel FK506-binding protein in avian progesterone receptor complexes and HeLa extracts.

PubMed ID: 7693698

DOI: 10.1016/s0021-9258(20)80520-1

PubMed ID: 11350175

Title: Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40.

PubMed ID: 11350175

DOI: 10.1006/jmbi.2001.4595

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26101251

Title: FKBP51 employs both scaffold and isomerase functions to promote NF-kappaB activation in melanoma.

PubMed ID: 26101251

DOI: 10.1093/nar/gkv615

PubMed ID: 28147277

Title: Regulation of serine-threonine kinase Akt activation by NAD+-dependent deacetylase SIRT7.

PubMed ID: 28147277

DOI: 10.1016/j.celrep.2017.01.009

PubMed ID: 28363942

Title: USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.

PubMed ID: 28363942

DOI: 10.15252/embj.201695669

PubMed ID: 31434731

Title: Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses.

PubMed ID: 31434731

DOI: 10.1128/jvi.01159-19

PubMed ID: 12538866

Title: Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes.

PubMed ID: 12538866

DOI: 10.1073/pnas.0231020100

Sequence Information:

  • Length: 457
  • Mass: 51212
  • Checksum: 18A86608C6891A73
  • Sequence:
    • MTTDEGAKNN EESPTATVAE QGEDITSKKD RGVLKIVKRV GNGEETPMIG DKVYVHYKGK 
LSNGKKFDSS HDRNEPFVFS LGKGQVIKAW DIGVATMKKG EICHLLCKPE YAYGSAGSLP 
KIPSNATLFF EIELLDFKGE DLFEDGGIIR RTKRKGEGYS NPNEGATVEI HLEGRCGGRM 
FDCRDVAFTV GEGEDHDIPI GIDKALEKMQ REEQCILYLG PRYGFGEAGK PKFGIEPNAE 
LIYEVTLKSF EKAKESWEMD TKEKLEQAAI VKEKGTVYFK GGKYMQAVIQ YGKIVSWLEM 
EYGLSEKESK ASESFLLAAF LNLAMCYLKL REYTKAVECC DKALGLDSAN EKGLYRRGEA 
QLLMNEFESA KGDFEKVLEV NPQNKAARLQ ISMCQKKAKE HNERDRRIYA NMFKKFAEQD 
AKEEANKAMG KKTSEGVTNE KGTDSQAMEE EKPEGHV

Genular Protein ID: 1777276483

Symbol: Q2TA84_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2TA84

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 1 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 Rhea 3 SAM 1 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 457
  • Mass: 51178
  • Checksum: 7189EB6B4E203875
  • Sequence:
    • MTTDEGAKNN EESPTATVAE QGEDITSKKD RGVLKIVKRV GNGEETPMIG DKVYVHYKGK 
LSNGKKFDSS HDRNEPFVFS LGKGQVIKAW DIGVATMKKG EICHLLCKPE YAYGSAGSLP 
KIPSNATLFF EIELLDLKGE DLFEDGGIIR RTKRKGEGYS NPNEGATVEI HLEGRCGGRM 
FDCRDVAFTV GEGEDHDIPI GIDKALEKMQ REEQCILYLG PRYGFGEAGK PKFGIEPNAE 
LIYEVTLKSF EKAKESWEMD TKEKLEQAAI VKEKGTVYFK GGKYMQAVIQ YGKIVSWLEM 
EYGLSEKESK ASESFLLAAF LNLAMCYLKL REYTKAVECC DKALGLDSAN EKGLYRRGEA 
QLLMNEFESA KGDFEKVLEV NPQNKAARLQ ISMCQKKAKE HNERDRRIYA NMFKKFAEQD 
AKEEANKAMG KKTSEGVTNE KGTDSQAMEE EKPEGHV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.