Details for: GALNS
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.23
Marker Score: 10674 - Cell Name: germ cell (CL0000586)
Fold Change: 1.14
Marker Score: 1989 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.07
Marker Score: 2035 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71761 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47984 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30401 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.97
Marker Score: 3351 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2405 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 487 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.94
Marker Score: 1447 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 441 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2718 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9
Marker Score: 14054 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.89
Marker Score: 32824 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5022 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5261 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.86
Marker Score: 408 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 0.82
Marker Score: 1562 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.8
Marker Score: 227 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.79
Marker Score: 1134 - Cell Name: oocyte (CL0000023)
Fold Change: 0.79
Marker Score: 195 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1267 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.77
Marker Score: 6648 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.77
Marker Score: 465 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.76
Marker Score: 701 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.76
Marker Score: 1547.5 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 581 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.74
Marker Score: 1749 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.74
Marker Score: 238 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.74
Marker Score: 891 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.73
Marker Score: 10950 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 377 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.72
Marker Score: 290 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.72
Marker Score: 207 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.69
Marker Score: 4160 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.69
Marker Score: 13746 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.69
Marker Score: 2888 - Cell Name: brush cell (CL0002204)
Fold Change: 0.68
Marker Score: 621 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.68
Marker Score: 41815 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.68
Marker Score: 2817 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.67
Marker Score: 25513 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 169 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.65
Marker Score: 6203 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.64
Marker Score: 4905 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.61
Marker Score: 291 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.58
Marker Score: 12389 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 433 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.54
Marker Score: 170 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.54
Marker Score: 596 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.54
Marker Score: 2070 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.52
Marker Score: 4925 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.51
Marker Score: 592 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.51
Marker Score: 5288 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5
Marker Score: 17397 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.49
Marker Score: 782 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.47
Marker Score: 213 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.46
Marker Score: 448 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.46
Marker Score: 11876 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.45
Marker Score: 225 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.45
Marker Score: 101 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.45
Marker Score: 295 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.45
Marker Score: 1922 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.44
Marker Score: 5828 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.44
Marker Score: 600 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.43
Marker Score: 1129 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.43
Marker Score: 106 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.43
Marker Score: 23986 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.43
Marker Score: 229 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.43
Marker Score: 178 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.42
Marker Score: 267 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.42
Marker Score: 806 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.42
Marker Score: 363 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.41
Marker Score: 1533 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.41
Marker Score: 88 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.41
Marker Score: 251 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.41
Marker Score: 130 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.41
Marker Score: 106 - Cell Name: interneuron (CL0000099)
Fold Change: 0.41
Marker Score: 185 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.4
Marker Score: 165 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.4
Marker Score: 496 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.4
Marker Score: 986 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.4
Marker Score: 566 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.4
Marker Score: 177 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.4
Marker Score: 431 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.4
Marker Score: 1086 - Cell Name: basal cell (CL0000646)
Fold Change: 0.4
Marker Score: 515 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.39
Marker Score: 137 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.39
Marker Score: 250 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.38
Marker Score: 84 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.38
Marker Score: 991 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.38
Marker Score: 242 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.38
Marker Score: 185 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.38
Marker Score: 97 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.38
Marker Score: 339 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 0.38
Marker Score: 2298 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.38
Marker Score: 379 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.38
Marker Score: 130 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.37
Marker Score: 450.5 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.37
Marker Score: 188
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Other Information
Genular Protein ID: 3608982954
Symbol: GALNS_HUMAN
Name: N-acetylgalactosamine-6-sulfatase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1755850
Title: Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6-sulfate sulfatase.
PubMed ID: 1755850
PubMed ID: 8001980
Title: Morquio A syndrome: cloning, sequence, and structure of the human N-acetylgalactosamine 6-sulfatase (GALNS) gene.
PubMed ID: 8001980
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 22940367
Title: The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A.
PubMed ID: 22940367
PubMed ID: 1522213
Title: Mucopolysaccharidosis type IVA. N-acetylgalactosamine-6-sulfate sulfatase exonic point mutations in classical Morquio and mild cases.
PubMed ID: 1522213
DOI: 10.1172/jci115919
PubMed ID: 7668283
Title: Mucopolysaccharidosis IVA: identification of a common missense mutation I113F in the N-Acetylgalactosamine-6-sulfate sulfatase gene.
PubMed ID: 7668283
PubMed ID: 7795586
Title: Mucopolysaccharidosis IVA: screening and identification of mutations of the N-acetylgalactosamine-6-sulfate sulfatase gene.
PubMed ID: 7795586
DOI: 10.1093/hmg/4.3.341
PubMed ID: 7633425
Title: Mucopolysaccharidosis type IVA: identification of six novel mutations among non-Japanese patients.
PubMed ID: 7633425
DOI: 10.1093/hmg/4.4.741
PubMed ID: 7581409
Title: Two new mutations, Q473X and N487S, in a Caucasian patient with mucopolysaccharidosis IVA (Morquio disease).
PubMed ID: 7581409
PubMed ID: 8651279
Title: Mucopolysaccharidosis IVA: four new exonic mutations in patients with N-acetylgalactosamine-6-sulfate sulfatase deficiency.
PubMed ID: 8651279
PubMed ID: 8826435
Title: Heteroallelic missense mutations of the galactosamine-6-sulfate sulfatase (GALNS) gene in a mild form of Morquio disease (MPS IVA).
PubMed ID: 8826435
DOI: 10.1002/(sici)1096-8628(19960628)63:4<558::aid-ajmg9>3.0.co;2-k
PubMed ID: 9298823
Title: Identification of 31 novel mutations in the N-acetylgalactosamine-6-sulfatase gene reveals excessive allelic heterogeneity among patients with Morquio A syndrome.
PubMed ID: 9298823
DOI: 10.1002/(sici)1098-1004(1997)10:3<223::aid-humu8>3.0.co;2-j
PubMed ID: 9375852
Title: Fourteen novel mucopolysaccharidosis IVA producing mutations in GALNS gene.
PubMed ID: 9375852
DOI: 10.1002/(sici)1098-1004(1997)10:5<368::aid-humu6>3.0.co;2-b
PubMed ID: 9521421
Title: Molecular heterogeneity in mucopolysaccharidosis IVA in Australia and Northern Ireland: nine novel mutations including T312S, a common allele that confers a mild phenotype.
PubMed ID: 9521421
DOI: 10.1002/(sici)1098-1004(1998)11:3<202::aid-humu4>3.0.co;2-j
PubMed ID: 9452036
Title: Fifteen polymorphisms in the N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene: diagnostic implications in Morquio disease.
PubMed ID: 9452036
PubMed ID: 16287098
Title: Mutation and polymorphism spectrum of the GALNS gene in mucopolysaccharidosis IVA (Morquio A).
PubMed ID: 16287098
DOI: 10.1002/humu.20257
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 24726177
Title: Molecular testing of 163 patients with Morquio A (Mucopolysaccharidosis IVA) identifies 39 novel GALNS mutations.
PubMed ID: 24726177
Sequence Information:
- Length: 522
- Mass: 58026
- Checksum: 1D086E528AAAE949
- Sequence:
MAAVVAATRW WQLLLVLSAA GMGASGAPQP PNILLLLMDD MGWGDLGVYG EPSRETPNLD RMAAEGLLFP NFYSANPLCS PSRAALLTGR LPIRNGFYTT NAHARNAYTP QEIVGGIPDS EQLLPELLKK AGYVSKIVGK WHLGHRPQFH PLKHGFDEWF GSPNCHFGPY DNKARPNIPV YRDWEMVGRY YEEFPINLKT GEANLTQIYL QEALDFIKRQ ARHHPFFLYW AVDATHAPVY ASKPFLGTSQ RGRYGDAVRE IDDSIGKILE LLQDLHVADN TFVFFTSDNG AALISAPEQG GSNGPFLCGK QTTFEGGMRE PALAWWPGHV TAGQVSHQLG SIMDLFTTSL ALAGLTPPSD RAIDGLNLLP TLLQGRLMDR PIFYYRGDTL MAATLGQHKA HFWTWTNSWE NFRQGIDFCP GQNVSGVTTH NLEDHTKLPL IFHLGRDPGE RFPLSFASAE YQEALSRITS VVQQHQEALV PAQPQLNVCN WAVMNWAPPG CEKLGKCLTP PESIPKKCLW SH
Genular Protein ID: 1926451998
Symbol: Q6YL38_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 337
- Mass: 37579
- Checksum: 7D6A6DBF166CE355
- Sequence:
MVGRYYEEFP INLKTGEANL TQIYLQEALD FIKRQARHHP FFLYWAVDAT HAPVYASKPF LGTSQRGRYG DAVREIDDSI GKILELLQDL HVADNTFVFF TSDNGAALIS APEQGGSNGP FLCGKQTTFE GGMREPALAW WPGHVTAGQV SHQLGSIMDL FTTSLALAGL TPPSDRAIDG LNLLPTLLQG RLMDRPIFYY RGDTLMAATL GQHKAHFWTW TNSWENFRQG IDFCPGQNVS GVTTHNLEDH TKLPLIFHLG RDPGERFPLS FASAEYQEAL SRITSVVQQH QEALVPAQPQ LNVCNWAVMN WAPPGCEKLG KCLTPPESIP KKCLWSH
Genular Protein ID: 3250203457
Symbol: Q96I49_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 238
- Mass: 26148
- Checksum: BC4810E73D89D5ED
- Sequence:
FTSDNGAALI SAPEQGGSNG PFLCGKQTTF EGGMREPALA WWPGHVTAGQ VSHQLGSIMD LFTTSLALAG LTPPSDRAID GLNLLPTLLQ GRLMDRPIFY YRGDTLMAAT LGQHKAHFWT WTNSWENFRQ GIDFCPGQNV SGVTTHNLED HTKLPLIFHL GRDPGERFPL SFASAEYQEA LSRITSVVQQ HQEALVPAQP QLNVCNWAVM NWAPPGCEKL GKCLTPPESI PKKCLWSH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.