Details for: BABAM1

Gene ID: 29086

Symbol: BABAM1

Ensembl ID: ENSG00000105393

Description: BRISC and BRCA1 A complex member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 158.7320
    Cell Significance Index: -24.6900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 113.1707
    Cell Significance Index: -28.7100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 81.6851
    Cell Significance Index: -33.6500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.8127
    Cell Significance Index: -36.2700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 76.2448
    Cell Significance Index: -30.9800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 69.0922
    Cell Significance Index: -35.5400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 54.5288
    Cell Significance Index: -36.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 32.6685
    Cell Significance Index: -31.1900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.0164
    Cell Significance Index: -33.3100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.4132
    Cell Significance Index: -37.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.9623
    Cell Significance Index: -21.3300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.5502
    Cell Significance Index: -23.1900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.0315
    Cell Significance Index: 209.6500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 2.3499
    Cell Significance Index: 273.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.2597
    Cell Significance Index: 58.7400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.0553
    Cell Significance Index: 22.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.9871
    Cell Significance Index: 34.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7840
    Cell Significance Index: 157.2700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7498
    Cell Significance Index: 48.3800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7498
    Cell Significance Index: 102.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6579
    Cell Significance Index: 30.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6483
    Cell Significance Index: 34.0400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.5977
    Cell Significance Index: 4.7700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5851
    Cell Significance Index: 319.5300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.5473
    Cell Significance Index: 5.9500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5434
    Cell Significance Index: 40.5000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5281
    Cell Significance Index: 476.7900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5061
    Cell Significance Index: 91.2300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.5017
    Cell Significance Index: 5.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4830
    Cell Significance Index: 62.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4511
    Cell Significance Index: 55.4700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4489
    Cell Significance Index: 198.4600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4344
    Cell Significance Index: 11.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4053
    Cell Significance Index: 51.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3197
    Cell Significance Index: 37.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2882
    Cell Significance Index: 20.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2857
    Cell Significance Index: 102.4900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2699
    Cell Significance Index: 14.0200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2272
    Cell Significance Index: 22.4800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1901
    Cell Significance Index: 9.6100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1745
    Cell Significance Index: 9.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1703
    Cell Significance Index: 7.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1685
    Cell Significance Index: 32.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1569
    Cell Significance Index: 26.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1547
    Cell Significance Index: 9.7500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1508
    Cell Significance Index: 4.0400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1348
    Cell Significance Index: 3.5400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0697
    Cell Significance Index: 1.8600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0631
    Cell Significance Index: 4.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0202
    Cell Significance Index: 3.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0198
    Cell Significance Index: 14.9900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0108
    Cell Significance Index: 0.1800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0074
    Cell Significance Index: -5.4000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0198
    Cell Significance Index: -37.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0263
    Cell Significance Index: -48.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0312
    Cell Significance Index: -1.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0316
    Cell Significance Index: -48.7200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0336
    Cell Significance Index: -24.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0383
    Cell Significance Index: -3.9100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0442
    Cell Significance Index: -1.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0502
    Cell Significance Index: -28.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0522
    Cell Significance Index: -33.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0800
    Cell Significance Index: -49.9800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0855
    Cell Significance Index: -38.7900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0979
    Cell Significance Index: -2.6700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1046
    Cell Significance Index: -30.0900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1048
    Cell Significance Index: -1.5700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1433
    Cell Significance Index: -1.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1707
    Cell Significance Index: -9.5800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1752
    Cell Significance Index: -5.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1776
    Cell Significance Index: -20.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1851
    Cell Significance Index: -36.7400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1998
    Cell Significance Index: -42.0800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2504
    Cell Significance Index: -36.4000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3422
    Cell Significance Index: -27.1100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3466
    Cell Significance Index: -7.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3596
    Cell Significance Index: -37.4500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3765
    Cell Significance Index: -3.0700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3797
    Cell Significance Index: -5.1800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4034
    Cell Significance Index: -16.5300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4352
    Cell Significance Index: -12.7800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4513
    Cell Significance Index: -7.9800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4600
    Cell Significance Index: -13.5500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4669
    Cell Significance Index: -8.6300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4965
    Cell Significance Index: -30.4400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5212
    Cell Significance Index: -11.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5250
    Cell Significance Index: -23.2200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6029
    Cell Significance Index: -13.9300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6153
    Cell Significance Index: -23.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.6248
    Cell Significance Index: -17.9100
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.6757
    Cell Significance Index: -4.4100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6879
    Cell Significance Index: -17.2000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.7235
    Cell Significance Index: -10.2800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.7312
    Cell Significance Index: -15.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7584
    Cell Significance Index: -24.1600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7648
    Cell Significance Index: -25.0400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7860
    Cell Significance Index: -28.8600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.8041
    Cell Significance Index: -28.1700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.8095
    Cell Significance Index: -6.8000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.8345
    Cell Significance Index: -7.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** BABAM1 is highly expressed in various cell types, including placental villous trophoblast, CD14-low, CD16-positive monocyte, erythroid progenitor cell, enteric smooth muscle cell, peripheral nervous system neuron, epithelial cell of nephron, pro-T cell, kidney epithelial cell, and proerythroblast. 2. **Protein Structure:** BABAM1 is a protein that interacts with BRCA1 and other proteins to form the BRISC complex, which is essential for DNA double-strand break repair. 3. **Function:** BABAM1 is involved in the regulation of DNA repair, particularly in the homology-directed repair (HDR) pathway, and plays a crucial role in maintaining genome stability. **Pathways and Functions:** 1. **DNA Double-Strand Break Repair:** BABAM1 is involved in the repair of DNA double-strand breaks through the HDR pathway, which is a critical mechanism for maintaining genome stability. 2. **Cell Cycle Regulation:** BABAM1 interacts with BRCA1 and other proteins to regulate cell cycle progression, particularly in the G2/M checkpoint. 3. **Deubiquitination:** BABAM1 is involved in the deubiquitination of proteins, which is essential for the regulation of DNA repair and cell cycle progression. 4. **Metalloprotease Activity:** BABAM1 has metalloprotease activity, which is involved in the processing of DNA double-strand break ends. **Clinical Significance:** 1. **Cancer:** Alterations in BABAM1 have been associated with various cancers, including breast, ovarian, and colon cancer. 2. **Genetic Disorders:** Mutations in BABAM1 have been linked to genetic disorders such as Fanconi anemia, which is characterized by congenital abnormalities and increased risk of cancer. 3. **Neurological Disorders:** BABAM1 has been implicated in the pathogenesis of neurological disorders such as Alzheimer's disease and Parkinson's disease. 4. **Radiation Response:** BABAM1 is involved in the response to ionizing radiation, which is essential for understanding the mechanisms of radiation-induced damage and developing strategies for radiation therapy. In conclusion, BABAM1 is a critical gene that plays a vital role in maintaining genome stability and regulating cell cycle progression. Its involvement in DNA double-strand break repair and cell cycle regulation makes it an important target for understanding the mechanisms of various diseases, including cancer, genetic disorders, and neurological disorders. Further research is needed to fully elucidate the functions of BABAM1 and its clinical significance in human disease.

Genular Protein ID: 3155542156

Symbol: BABA1_HUMAN

Name: BRISC and BRCA1-A complex member 1

UniProtKB Accession Codes:

Q9NWV8 A8MQT0 B4DRY9 B4DVR1 Q6FIA0 Q9P018

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 10 EMDB 2 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19214193

Title: K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1.

PubMed ID: 19214193

DOI: 10.1038/emboj.2009.27

PubMed ID: 19261746

Title: MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

PubMed ID: 19261746

DOI: 10.1101/gad.1739609

PubMed ID: 19261749

Title: NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

PubMed ID: 19261749

DOI: 10.1101/gad.1770309

PubMed ID: 19261748

Title: MERIT40 facilitates BRCA1 localization and DNA damage repair.

PubMed ID: 19261748

DOI: 10.1101/gad.1770609

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21282113

Title: NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes.

PubMed ID: 21282113

DOI: 10.1074/jbc.m110.200857

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24075985

Title: A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses.

PubMed ID: 24075985

DOI: 10.1016/j.celrep.2013.08.025

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25283148

Title: ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53.

PubMed ID: 25283148

DOI: 10.1038/ncomms6059

PubMed ID: 26195665

Title: The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.

PubMed ID: 26195665

DOI: 10.1083/jcb.201503039

Sequence Information:

  • Length: 329
  • Mass: 36560
  • Checksum: 7A84D8EE6D03C1DB
  • Sequence:
    • MEVAEPSSPT EEEEEEEEHS AEPRPRTRSN PEGAEDRAVG AQASVGSRSE GEGEAASADD 
GSLNTSGAGP KSWQVPPPAP EVQIRTPRVN CPEKVIICLD LSEEMSLPKL ESFNGSKTNA 
LNVSQKMIEM FVRTKHKIDK SHEFALVVVN DDTAWLSGLT SDPRELCSCL YDLETASCST 
FNLEGLFSLI QQKTELPVTE NVQTIPPPYV VRTILVYSRP PCQPQFSLTE PMKKMFQCPY 
FFFDVVYIHN GTEEKEEEMS WKDMFAFMGS LDTKGTSYKY EVALAGPALE LHNCMAKLLA 
HPLQRPCQSH ASYSLLEEED EAIEVEATV

Genular Protein ID: 1375995096

Symbol: J3KQS6_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KQS6 M0QX07

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 GO 6 GeneTree 1 HGNC 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 254
  • Mass: 28164
  • Checksum: DB72BFDBA8185E43
  • Sequence:
    • MEVAEPSSPT EEEEEEEEHS AEPRPRTRSN PEGAEDRAVG AQASVGSRSE GEGEAASADD 
GSLNTSGAGP KSWQVPPPAP EVQIRTPRVN CPEKVIICLD LSEEMSLPKL ESFNGQQKTE 
LPVTENVQTI PPPYVVRTIL VYSRPPCQPQ FSLTEPMKKM FQCPYFFFDV VYIHNGTEEK 
EEEMSWKDMF AFMGSLDTKG TSYKYEVALA GPALELHNCM AKLLAHPLQR PCQSHASYSL 
LEEEDEAIEV EATV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.