Details for: BRD7

Gene ID: 29117

Symbol: BRD7

Ensembl ID: ENSG00000166164

Description: bromodomain containing 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 274.0039
    Cell Significance Index: -42.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 176.3500
    Cell Significance Index: -44.7300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 133.3665
    Cell Significance Index: -54.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 112.7885
    Cell Significance Index: -53.2500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 105.8197
    Cell Significance Index: -42.9900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 96.5230
    Cell Significance Index: -49.6500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 79.4162
    Cell Significance Index: -53.2900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 45.4992
    Cell Significance Index: -43.4400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 39.4418
    Cell Significance Index: -48.6300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.8434
    Cell Significance Index: -47.8000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.5632
    Cell Significance Index: -49.5800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.3681
    Cell Significance Index: -24.8800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.0567
    Cell Significance Index: -33.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 4.0408
    Cell Significance Index: 470.9100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 3.2543
    Cell Significance Index: 44.4000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.0175
    Cell Significance Index: 219.4400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7044
    Cell Significance Index: 45.5100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5620
    Cell Significance Index: 281.5800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.5247
    Cell Significance Index: 187.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.2776
    Cell Significance Index: 82.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1911
    Cell Significance Index: 236.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1860
    Cell Significance Index: 647.6900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.1565
    Cell Significance Index: 33.3200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.0768
    Cell Significance Index: 8.3000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0547
    Cell Significance Index: 54.9400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.0524
    Cell Significance Index: 8.8400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.0360
    Cell Significance Index: 71.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.0108
    Cell Significance Index: 56.7200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.9813
    Cell Significance Index: 24.5300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8898
    Cell Significance Index: 40.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8739
    Cell Significance Index: 120.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8526
    Cell Significance Index: 376.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7460
    Cell Significance Index: 149.6600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7255
    Cell Significance Index: 51.3100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7080
    Cell Significance Index: 6.5200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7065
    Cell Significance Index: 19.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6826
    Cell Significance Index: 15.7700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6448
    Cell Significance Index: 40.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6126
    Cell Significance Index: 28.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6109
    Cell Significance Index: 31.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5988
    Cell Significance Index: 59.2300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4764
    Cell Significance Index: 430.1400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4062
    Cell Significance Index: 19.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4056
    Cell Significance Index: 145.4700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4041
    Cell Significance Index: 279.5200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3283
    Cell Significance Index: 56.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3244
    Cell Significance Index: 19.9400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2749
    Cell Significance Index: 35.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2410
    Cell Significance Index: 28.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2177
    Cell Significance Index: 27.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1982
    Cell Significance Index: 6.9700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1578
    Cell Significance Index: 11.7600
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.1417
    Cell Significance Index: 1.0700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0752
    Cell Significance Index: 115.8400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0628
    Cell Significance Index: 118.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0611
    Cell Significance Index: 112.7400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0390
    Cell Significance Index: 7.4200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0325
    Cell Significance Index: 1.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0285
    Cell Significance Index: 20.8900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0247
    Cell Significance Index: 33.5400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0184
    Cell Significance Index: 1.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0163
    Cell Significance Index: 2.6500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0104
    Cell Significance Index: 6.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0149
    Cell Significance Index: -6.7700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0187
    Cell Significance Index: -13.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0243
    Cell Significance Index: -18.3800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0294
    Cell Significance Index: -0.6100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0309
    Cell Significance Index: -19.2900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0395
    Cell Significance Index: -22.2600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1002
    Cell Significance Index: -21.1000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1208
    Cell Significance Index: -12.3400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1374
    Cell Significance Index: -39.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1377
    Cell Significance Index: -3.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1642
    Cell Significance Index: -4.5900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1724
    Cell Significance Index: -25.0600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1975
    Cell Significance Index: -3.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1991
    Cell Significance Index: -10.0600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2104
    Cell Significance Index: -24.0200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2157
    Cell Significance Index: -24.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2532
    Cell Significance Index: -11.2000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3387
    Cell Significance Index: -9.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3521
    Cell Significance Index: -13.3400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3597
    Cell Significance Index: -7.5300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3635
    Cell Significance Index: -7.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3862
    Cell Significance Index: -30.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4184
    Cell Significance Index: -43.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4227
    Cell Significance Index: -28.4300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4569
    Cell Significance Index: -7.8300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4734
    Cell Significance Index: -2.8600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5782
    Cell Significance Index: -4.7200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5785
    Cell Significance Index: -12.3200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5852
    Cell Significance Index: -8.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5906
    Cell Significance Index: -18.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6356
    Cell Significance Index: -33.3700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6532
    Cell Significance Index: -16.7900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7234
    Cell Significance Index: -44.3500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7342
    Cell Significance Index: -19.6400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.7618
    Cell Significance Index: -18.2700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.7793
    Cell Significance Index: -15.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.8002
    Cell Significance Index: -14.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Bromodomain structure:** The BRD7 protein contains a highly conserved bromodomain, which is responsible for its interaction with acetylated histones and other transcriptional regulators. 2. **Histone binding:** BRD7 binds to acetylated histones, particularly H3K27ac, and recruits other transcriptional regulators to specific genomic regions. 3. **Transcriptional regulation:** BRD7 acts as a transcriptional coactivator or corepressor, depending on the context, and regulates the expression of target genes involved in cell differentiation, proliferation, and survival. 4. **Cell-type specificity:** BRD7 is expressed in various cell types, including immune cells, germ cells, and epithelial cells, suggesting its involvement in multiple cellular processes. 5. **Disease association:** BRD7 dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and neurological disorders. **Pathways and Functions:** 1. **Cell cycle regulation:** BRD7 regulates the G1/S transition of the cell cycle by interacting with p53 and other transcriptional regulators. 2. **Gene expression:** BRD7 regulates the expression of target genes involved in cell differentiation, proliferation, and survival by interacting with RNA polymerase II and other transcriptional regulators. 3. **Chromatin remodeling:** BRD7 interacts with chromatin remodeling complexes, such as RSC, to regulate chromatin structure and transcriptional access. 4. **DNA damage response:** BRD7 regulates the response to DNA damage by interacting with p53 and other transcriptional regulators involved in double-strand break repair. 5. **Immune cell development:** BRD7 is essential for the development and function of immune cells, including T cells and B cells. **Clinical Significance:** 1. **Cancer:** BRD7 dysregulation has been implicated in various cancers, including lymphoma, leukemia, and breast cancer. 2. **Autoimmune disorders:** BRD7 dysregulation has been linked to autoimmune disorders, such as rheumatoid arthritis and lupus. 3. **Neurological disorders:** BRD7 dysregulation has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Immunotherapy:** BRD7 is a potential target for immunotherapy, given its role in immune cell development and function. 5. **Cancer therapy:** BRD7 inhibition has been explored as a potential therapeutic strategy for cancer treatment. In conclusion, the BRD7 gene plays a critical role in regulating transcriptional activities and cell differentiation. Its dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and neurological disorders. Further research is needed to fully understand the mechanisms of BRD7 regulation and its clinical significance.

Genular Protein ID: 2593632114

Symbol: BRD7_HUMAN

Name: Bromodomain-containing protein 7

UniProtKB Accession Codes:

Q9NPI1 Q4VC09 Q8N2L9 Q96KA4 Q9BV48 Q9UH59

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EMDB 2 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11025449

Title: Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2.

PubMed ID: 11025449

DOI: 10.1002/1097-4652(200011)185:2<269::aid-jcp12>3.0.co;2-l

PubMed ID: 12489984

Title: Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7.

PubMed ID: 12489984

DOI: 10.1042/bj20021281

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16265664

Title: The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain.

PubMed ID: 16265664

DOI: 10.1002/jcb.20645

PubMed ID: 16475162

Title: Identification of nuclear localization signal that governs nuclear import of BRD7 and its essential roles in inhibiting cell cycle progression.

PubMed ID: 16475162

DOI: 10.1002/jcb.20788

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 20215511

Title: BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

PubMed ID: 20215511

DOI: 10.1158/0008-5472.can-09-2089

PubMed ID: 20228809

Title: BRD7 is a candidate tumour suppressor gene required for p53 function.

PubMed ID: 20228809

DOI: 10.1038/ncb2038

PubMed ID: 20660729

Title: Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence.

PubMed ID: 20660729

DOI: 10.1073/pnas.1009559107

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 17498659

Title: Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4.

PubMed ID: 17498659

DOI: 10.1016/j.bbrc.2007.04.139

Sequence Information:

  • Length: 651
  • Mass: 74139
  • Checksum: 29B7947644C215E7
  • Sequence:
    • MGKKHKKHKS DKHLYEEYVE KPLKLVLKVG GNEVTELSTG SSGHDSSLFE DKNDHDKHKD 
RKRKKRKKGE KQIPGEEKGR KRRRVKEDKK KRDRDRVENE AEKDLQCHAP VRLDLPPEKP 
LTSSLAKQEE VEQTPLQEAL NQLMRQLQRK DPSAFFSFPV TDFIAPGYSM IIKHPMDFST 
MKEKIKNNDY QSIEELKDNF KLMCTNAMIY NKPETIYYKA AKKLLHSGMK ILSQERIQSL 
KQSIDFMADL QKTRKQKDGT DTSQSGEDGG CWQREREDSG DAEAHAFKSP SKENKKKDKD 
MLEDKFKSNN LEREQEQLDR IVKESGGKLT RRLVNSQCEF ERRKPDGTTT LGLLHPVDPI 
VGEPGYCPVR LGMTTGRLQS GVNTLQGFKE DKRNKVTPVL YLNYGPYSSY APHYDSTFAN 
ISKDDSDLIY STYGEDSDLP SDFSIHEFLA TCQDYPYVMA DSLLDVLTKG GHSRTLQEME 
MSLPEDEGHT RTLDTAKEME ITEVEPPGRL DSSTQDRLIA LKAVTNFGVP VEVFDSEEAE 
IFQKKLDETT RLLRELQEAQ NERLSTRPPP NMICLLGPSY REMHLAEQVT NNLKELAQQV 
TPGDIVSTYG VRKAMGISIP SPVMENNFVD LTEDTEEPKK TDVAECGPGG S

Genular Protein ID: 2527034335

Symbol: A0AA34QVS2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0AA34QVS2

Database IDs:

CDD 1 CTD 1 EMBL 3 Ensembl 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 668
  • Mass: 76136
  • Checksum: 5CB06770B68B7BE6
  • Sequence:
    • MGKKHKKHKS DKHLYEEYVE KPLKLVLKVG GNEVTELSTG SSGHDSSLFE DKNDHDKHKD 
RKRKKRKKGE KQIPGEEKGR KRRRVKVQVV TLLWLCGRHC LFQEDKKKRD RDRVENEAEK 
DLQCHAPVRL DLPPEKPLTS SLAKQEEVEQ TPLQEALNQL MRQLQRKDPS AFFSFPVTDF 
IAPGYSMIIK HPMDFSTMKE KIKNNDYQSI EELKDNFKLM CTNAMIYNKP ETIYYKAAKK 
LLHSGMKILS QERIQSLKQS IDFMADLQKT RKQKDGTDTS QSGEDGGCWQ REREDSGDAE 
AHAFKSPSKE NKKKDKDMLE DKFKSNNLER EQEQLDRIVK ESGGKLTRRL VNSQCEFERR 
KPDGTTTLGL LHPVDPIVGE PGYCPVRLGM TTGRLQSGVN TLQGFKEDKR NKVTPVLYLN 
YGPYSSYAPH YDSTFANISK DDSDLIYSTY GEDSDLPSDF SIHEFLATCQ DYPYVMADSL 
LDVLTKGGHS RTLQEMEMSL PEDEGHTRTL DTAKEMEITE VEPPGRLDSS TQDRLIALKA 
VTNFGVPVEV FDSEEAEIFQ KKLDETTRLL RELQEAQNER LSTRPPPNMI CLLGPSYREM 
HLAEQVTNNL KELAQQVTPG DIVSTYGVRK AMGISIPSPV MENNFVDLTE DTEEPKKTDV 
AECGPGGS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.