Details for: PACSIN3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: enterocyte of colon (CL1000347)
Fold Change: 3
Marker Score: 4,627 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.59
Marker Score: 1,155 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 169,040 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 1.24
Marker Score: 10,486 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.2
Marker Score: 18,711 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.19
Marker Score: 10,279 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.08
Marker Score: 592 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 1.06
Marker Score: 8,278 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.03
Marker Score: 784 - Cell Name: peptic cell (CL0000155)
Fold Change: 1.01
Marker Score: 424 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,799 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,023 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1
Marker Score: 2,269 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.98
Marker Score: 3,640 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.97
Marker Score: 501 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 454 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 0.95
Marker Score: 338 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,411 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.92
Marker Score: 1,017 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.92
Marker Score: 367 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,731 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5,195 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.91
Marker Score: 1,611 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.9
Marker Score: 934 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 319 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.87
Marker Score: 728 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,277 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.84
Marker Score: 1,768 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 0.83
Marker Score: 264 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.82
Marker Score: 6,088 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.8
Marker Score: 1,678 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.79
Marker Score: 1,498 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.79
Marker Score: 827 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,269 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.77
Marker Score: 244 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.77
Marker Score: 1,562 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.76
Marker Score: 2,993 - Cell Name: brush cell (CL0002204)
Fold Change: 0.75
Marker Score: 689 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.75
Marker Score: 390 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.75
Marker Score: 1,698 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.73
Marker Score: 773 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.73
Marker Score: 1,774 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.72
Marker Score: 482 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.71
Marker Score: 2,978 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.69
Marker Score: 440 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.69
Marker Score: 15,357 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 175 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.68
Marker Score: 723 - Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
Fold Change: 0.67
Marker Score: 161 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.66
Marker Score: 919 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.65
Marker Score: 310 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.65
Marker Score: 1,520 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.64
Marker Score: 301 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.64
Marker Score: 1,084 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.63
Marker Score: 2,421 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.63
Marker Score: 588 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.62
Marker Score: 178 - Cell Name: malignant cell (CL0001064)
Fold Change: 0.61
Marker Score: 8,220 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.61
Marker Score: 733 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 0.61
Marker Score: 462 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.61
Marker Score: 182 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.59
Marker Score: 1,390 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.59
Marker Score: 2,097 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.57
Marker Score: 403 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.57
Marker Score: 908 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.56
Marker Score: 7,421 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 0.56
Marker Score: 277 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.56
Marker Score: 258 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.56
Marker Score: 862 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.56
Marker Score: 232 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.55
Marker Score: 891 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.55
Marker Score: 333 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.55
Marker Score: 436 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.55
Marker Score: 141 - Cell Name: neural cell (CL0002319)
Fold Change: 0.55
Marker Score: 266 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.55
Marker Score: 1,026 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.54
Marker Score: 170 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.54
Marker Score: 3,503 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.52
Marker Score: 5,856 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 0.51
Marker Score: 153 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.5
Marker Score: 293 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.5
Marker Score: 335 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 0.49
Marker Score: 2,594 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.49
Marker Score: 160 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.48
Marker Score: 330 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.48
Marker Score: 164 - Cell Name: T-helper 17 cell (CL0000899)
Fold Change: 0.48
Marker Score: 316 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.48
Marker Score: 299 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.47
Marker Score: 776 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 0.47
Marker Score: 420 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.47
Marker Score: 856 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.47
Marker Score: 442 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 0.46
Marker Score: 605 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.46
Marker Score: 677 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.46
Marker Score: 552 - Cell Name: Unknown (CL0000003)
Fold Change: 0.45
Marker Score: 1,398 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.45
Marker Score: 2,940 - Cell Name: basal cell (CL0000646)
Fold Change: 0.45
Marker Score: 579
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2343175138
Symbol: PACN3_HUMAN
Name: Protein kinase C and casein kinase substrate in neurons protein 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10531379
Title: Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.
PubMed ID: 10531379
PubMed ID: 11082044
Title: All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.
PubMed ID: 11082044
PubMed ID: 11179684
Title: PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.
PubMed ID: 11179684
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23236520
Title: Versatile membrane deformation potential of activated pacsin.
PubMed ID: 23236520
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 424
- Mass: 48487
- Checksum: 6DBD940AE6D1F352
- Sequence:
MAPEEDAGGE ALGGSFWEAG NYRRTVQRVE DGHRLCGDLV SCFQERARIE KAYAQQLADW ARKWRGTVEK GPQYGTLEKA WHAFFTAAER LSALHLEVRE KLQGQDSERV RAWQRGAFHR PVLGGFRESR AAEDGFRKAQ KPWLKRLKEV EASKKSYHAA RKDEKTAQTR ESHAKADSAV SQEQLRKLQE RVERCAKEAE KTKAQYEQTL AELHRYTPRY MEDMEQAFET CQAAERQRLL FFKDMLLTLH QHLDLSSSEK FHELHRDLHQ GIEAASDEED LRWWRSTHGP GMAMNWPQFE EWSLDTQRTI SRKEKGGRSP DEVTLTSIVP TRDGTAPPPQ SPGSPGTGQD EEWSDEESPR KAATGVRVRA LYDYAGQEAD ELSFRAGEEL LKMSEEDEQG WCQGQLQSGR IGLYPANYVE CVGA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.