Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 5.44
Marker Score: 15880 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 4.38
Marker Score: 12094 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 3.67
Marker Score: 5407 - Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: 3.2
Marker Score: 1766 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 3.19
Marker Score: 10065 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 2.77
Marker Score: 1196 - Cell Name: memory T cell (CL0000813)
Fold Change: 2.48
Marker Score: 1066 - Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 2.38
Marker Score: 2645 - Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
Fold Change: 2.38
Marker Score: 783 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 2.16
Marker Score: 2978 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 2.12
Marker Score: 1865 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 1.98
Marker Score: 1434 - Cell Name: ILC1, human (CL0001077)
Fold Change: 1.82
Marker Score: 461 - Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
Fold Change: 1.7
Marker Score: 386 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: 1.69
Marker Score: 1306 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 1.67
Marker Score: 1617 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.59
Marker Score: 1152 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 1.48
Marker Score: 455 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 1.47
Marker Score: 848 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.4
Marker Score: 13899 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 1.2
Marker Score: 807 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 1.19
Marker Score: 313 - Cell Name: natural killer cell (CL0000623)
Fold Change: 1.11
Marker Score: 1440 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.09
Marker Score: 2068 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.05
Marker Score: 628 - Cell Name: blood cell (CL0000081)
Fold Change: 1.03
Marker Score: 11961 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.03
Marker Score: 784 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 1.02
Marker Score: 2487 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 1.01
Marker Score: 521 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71785 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48010 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.99
Marker Score: 837 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30406 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.98
Marker Score: 663.5 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.98
Marker Score: 406 - Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
Fold Change: 0.97
Marker Score: 1586 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.97
Marker Score: 500 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 454 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2410 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 0.93
Marker Score: 763 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5265 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.91
Marker Score: 366 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2732 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 319 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 0.88
Marker Score: 455.5 - Cell Name: Unknown (CL0000548)
Fold Change: 0.88
Marker Score: 640 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5285 - Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
Fold Change: 0.8
Marker Score: 707 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.79
Marker Score: 5080 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.78
Marker Score: 394 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1262 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.78
Marker Score: 659 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.77
Marker Score: 1568 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 699 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.75
Marker Score: 389 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 0.74
Marker Score: 435 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.74
Marker Score: 3101 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.7
Marker Score: 1969 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.66
Marker Score: 408 - Cell Name: mature NK T cell (CL0000814)
Fold Change: 0.62
Marker Score: 285 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.61
Marker Score: 391 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.6
Marker Score: 9365 - Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 0.58
Marker Score: 190 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.58
Marker Score: 314 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.58
Marker Score: 455 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.54
Marker Score: 172 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.54
Marker Score: 718 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.52
Marker Score: 137 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.52
Marker Score: 237 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.51
Marker Score: 372 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.51
Marker Score: 185 - Cell Name: mast cell (CL0000097)
Fold Change: 0.47
Marker Score: 272.5 - Cell Name: T-helper 17 cell (CL0000899)
Fold Change: 0.46
Marker Score: 301 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.46
Marker Score: 272 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.46
Marker Score: 345 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.45
Marker Score: 141 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.45
Marker Score: 399 - Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
Fold Change: 0.45
Marker Score: 1006 - Cell Name: intermediate monocyte (CL0002393)
Fold Change: 0.44
Marker Score: 152 - Cell Name: respiratory basal cell (CL0002633)
Fold Change: 0.42
Marker Score: 609 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.41
Marker Score: 196 - Cell Name: follicular B cell (CL0000843)
Fold Change: 0.41
Marker Score: 441.5 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.4
Marker Score: 644 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.39
Marker Score: 220 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.37
Marker Score: 912 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.34
Marker Score: 350 - Cell Name: B cell (CL0000236)
Fold Change: 0.34
Marker Score: 323 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.34
Marker Score: 878 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.33
Marker Score: 64 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.31
Marker Score: 179 - Cell Name: monocyte (CL0000576)
Fold Change: 0.31
Marker Score: 402 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.3
Marker Score: 76 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.3
Marker Score: 297 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.29
Marker Score: 69 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.29
Marker Score: 566 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.29
Marker Score: 62.5 - Cell Name: IgG plasma cell (CL0000985)
Fold Change: 0.28
Marker Score: 122 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.28
Marker Score: 62
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Other Information
Genular Protein ID: 2848280664
Symbol: GRAB_HUMAN
Name: C11
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2953813
Title: Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes.
PubMed ID: 2953813
PubMed ID: 3258865
Title: Structure and differential mechanisms of regulation of expression of a serine esterase gene in activated human T lymphocytes.
PubMed ID: 3258865
PubMed ID: 3261871
Title: Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes.
PubMed ID: 3261871
PubMed ID: 2788607
Title: Genomic organization and chromosomal assignment for a serine protease gene (CSPB) expressed by human cytotoxic lymphocytes.
PubMed ID: 2788607
PubMed ID: 2365998
Title: Nucleotide sequence and genomic organization of a human T lymphocyte serine protease gene.
PubMed ID: 2365998
PubMed ID: 2332171
Title: Structural organization of the hCTLA-1 gene encoding human granzyme B.
PubMed ID: 2332171
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2323780
Title: Isolation of a cDNA clone encoding a novel form of granzyme B from human NK cells and mapping to chromosome 14.
PubMed ID: 2323780
DOI: 10.1007/bf00195821
PubMed ID: 3262682
Title: Characterization of three serine esterases isolated from human IL-2 activated killer cells.
PubMed ID: 3262682
PubMed ID: 3263427
Title: Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes.
PubMed ID: 3263427
PubMed ID: 8258716
Title: Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes.
PubMed ID: 8258716
PubMed ID: 1985927
Title: Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity.
PubMed ID: 1985927
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 9852092
Title: Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.
PubMed ID: 9852092
PubMed ID: 20038786
Title: Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis.
PubMed ID: 20038786
PubMed ID: 24088571
Title: Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity.
PubMed ID: 24088571
PubMed ID: 32188940
Title: Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
PubMed ID: 32188940
PubMed ID: 31953257
Title: Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome.
PubMed ID: 31953257
PubMed ID: 11209755
Title: Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
PubMed ID: 11209755
DOI: 10.1515/bc.2000.148
PubMed ID: 11325591
Title: The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.
PubMed ID: 11325591
PubMed ID: 12721789
Title: Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population.
PubMed ID: 12721789
Sequence Information:
- Length: 247
- Mass: 27716
- Checksum: C652271918EF24F9
- Sequence:
MQPILLLLAF LLLPRADAGE IIGGHEAKPH SRPYMAYLMI WDQKSLKRCG GFLIRDDFVL TAAHCWGSSI NVTLGAHNIK EQEPTQQFIP VKRPIPHPAY NPKNFSNDIM LLQLERKAKR TRAVQPLRLP SNKAQVKPGQ TCSVAGWGQT APLGKHSHTL QEVKMTVQED RKCESDLRHY YDSTIELCVG DPEIKKTSFK GDSGGPLVCN KVAQGIVSYG RNNGMPPRAC TKVSSFVHWI KKTMKRY
Genular Protein ID: 644944040
Symbol: Q67BC3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 281
- Mass: 31392
- Checksum: 6CAD21A1A7E9DA44
- Sequence:
MKSLSLLHLF PLPRAKREQG GNNSSSNQGS LPEKMQPILL LLAFLLLPRA DAGEIIGGHE AKPHSRPYMA YLMIWDQKSL KRCGGFLIQD DFVLTAAHCW GSSINVTLGA HNIKEQEPTQ QFIPVKRPIP HPAYNPKNFS NDIMLLQLER KAKRTRAVQP LRLPSNKAQV KPGQTCSVAG WGQTAPLGKH SHTLQEVKMT VQEDRKCESD LRHYYDSTIE LCVGDPEIKK TSFKGDSGGP LVCNKVAQGI VSYGRNNGMP PRACTKVSSF VHWIKKTMKR Y
Genular Protein ID: 2503191846
Symbol: Q6XGZ4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 235
- Mass: 26389
- Checksum: E80E1075882803F8
- Sequence:
MQTFPSGEII GGHEAKPHSR PYMAYLMIWD QKSLKRCGGF LIQDDFVLTA AHCWGSSINV TLGAHNIKEQ EPTQQFIPVK RPIPHPAYNP KNFSNDIMLL QLERKAKRTR AVQPLRLPSN KAQVKPGQTC SVAGWGQTAP LGKHSHTLQE VKMTVQEDRK CESDLRHYYD STIELCVGDP EIKKTSFKGD SGGPLVCNKV AQGIVSYGRN NGMPPRACTK VSSFVHWIKK TMKRY
Genular Protein ID: 3781808694
Symbol: J3KQ52_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
Sequence Information:
- Length: 235
- Mass: 26417
- Checksum: 4613C1694635D3FA
- Sequence:
MQTFPSGEII GGHEAKPHSR PYMAYLMIWD QKSLKRCGGF LIRDDFVLTA AHCWGSSINV TLGAHNIKEQ EPTQQFIPVK RPIPHPAYNP KNFSNDIMLL QLERKAKRTR AVQPLRLPSN KAQVKPGQTC SVAGWGQTAP LGKHSHTLQE VKMTVQEDRK CESDLRHYYD STIELCVGDP EIKKTSFKGD SGGPLVCNKV AQGIVSYGRN NGMPPRACTK VSSFVHWIKK TMKRY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.