Details for: HARS1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 2.18
Marker Score: 1946 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 2.18
Marker Score: 2132 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.63
Marker Score: 3448 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.55
Marker Score: 95225 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.46
Marker Score: 13869 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.44
Marker Score: 1915 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.44
Marker Score: 14855 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.4
Marker Score: 12015 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 1.39
Marker Score: 931 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.36
Marker Score: 12800.5 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.33
Marker Score: 904 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.32
Marker Score: 2034 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.31
Marker Score: 981 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.31
Marker Score: 48237 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.24
Marker Score: 24610.5 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.22
Marker Score: 16290 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.22
Marker Score: 2545 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.22
Marker Score: 18176 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.21
Marker Score: 509 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.21
Marker Score: 1361 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.2
Marker Score: 5185 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.18
Marker Score: 1252 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.17
Marker Score: 44305 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.16
Marker Score: 1458.5 - Cell Name: enteric neuron (CL0007011)
Fold Change: 1.16
Marker Score: 616 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.15
Marker Score: 332 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.15
Marker Score: 8829.5 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.15
Marker Score: 7363 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.15
Marker Score: 4756 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 1.15
Marker Score: 1195 - Cell Name: pro-T cell (CL0000827)
Fold Change: 1.14
Marker Score: 4677 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.14
Marker Score: 4399 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.11
Marker Score: 739 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.1
Marker Score: 2242 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.09
Marker Score: 1860 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.09
Marker Score: 410 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.09
Marker Score: 365 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.08
Marker Score: 991.5 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.08
Marker Score: 1551.5 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.07
Marker Score: 1081 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.04
Marker Score: 8991 - Cell Name: Unknown (CL0002371)
Fold Change: 1.04
Marker Score: 1102 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.03
Marker Score: 3832 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.03
Marker Score: 4067 - Cell Name: neuron (CL0000540)
Fold Change: 1.03
Marker Score: 4210 - Cell Name: blood cell (CL0000081)
Fold Change: 1.03
Marker Score: 11944 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.01
Marker Score: 237 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1
Marker Score: 2280 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1
Marker Score: 2353 - Cell Name: Unknown (CL0000548)
Fold Change: 1
Marker Score: 728 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71637.5 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47861.5 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.99
Marker Score: 271 - Cell Name: unswitched memory B cell (CL0000970)
Fold Change: 0.99
Marker Score: 580 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.99
Marker Score: 1065 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.99
Marker Score: 673 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30379 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.97
Marker Score: 1020 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.97
Marker Score: 2634 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.96
Marker Score: 1580.5 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.96
Marker Score: 1158 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.96
Marker Score: 4435 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.95
Marker Score: 1392 - Cell Name: oocyte (CL0000023)
Fold Change: 0.94
Marker Score: 233 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2389 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.93
Marker Score: 381 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.93
Marker Score: 511 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476.5 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 0.91
Marker Score: 430 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.91
Marker Score: 1779 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.91
Marker Score: 478 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.91
Marker Score: 451 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 0.9
Marker Score: 660 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.9
Marker Score: 1273 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.9
Marker Score: 1687 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2681 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.89
Marker Score: 928 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5080 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.89
Marker Score: 11714 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.89
Marker Score: 836 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.89
Marker Score: 741 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.89
Marker Score: 8927.5 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.88
Marker Score: 588 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.88
Marker Score: 9934 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.88
Marker Score: 523 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.88
Marker Score: 1351.5 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5290 - Cell Name: follicular B cell (CL0000843)
Fold Change: 0.87
Marker Score: 945 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.87
Marker Score: 305 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.87
Marker Score: 8822.5 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.87
Marker Score: 2366 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.87
Marker Score: 549 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.87
Marker Score: 5642 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 310 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.86
Marker Score: 918 - Cell Name: basal cell (CL0000646)
Fold Change: 0.85
Marker Score: 1103 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.85
Marker Score: 18105 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.83
Marker Score: 236 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.83
Marker Score: 199
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Other Information
Genular Protein ID: 3167441631
Symbol: HARS1_HUMAN
Name: Histidine--tRNA ligase, cytoplasmic
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1549469
Title: Human histidyl-tRNA synthetase: recognition of amino acid signature regions in class 2a aminoacyl-tRNA synthetases.
PubMed ID: 1549469
PubMed ID: 3554142
Title: Isolation, structure and expression of mammalian genes for histidyl-tRNA synthetase.
PubMed ID: 3554142
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8406012
Title: Transcriptional analyses of the gene region that encodes human histidyl-tRNA synthetase: identification of a novel bidirectional regulatory element.
PubMed ID: 8406012
PubMed ID: 7755634
Title: A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS.
PubMed ID: 7755634
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22930593
Title: A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo.
PubMed ID: 22930593
DOI: 10.1002/humu.22210
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26072516
Title: Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies.
PubMed ID: 26072516
DOI: 10.1093/brain/awv158
PubMed ID: 25151410
Title: Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases.
PubMed ID: 25151410
PubMed ID: 22279524
Title: Genetic mapping and exome sequencing identify variants associated with five novel diseases.
PubMed ID: 22279524
PubMed ID: 29235198
Title: Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy.
PubMed ID: 29235198
DOI: 10.1002/humu.23380
Sequence Information:
- Length: 509
- Mass: 57411
- Checksum: 65D8BB71CE79B1FF
- Sequence:
MAERAALEEL VKLQGERVRG LKQQKASAEL IEEEVAKLLK LKAQLGPDES KQKFVLKTPK GTRDYSPRQM AVREKVFDVI IRCFKRHGAE VIDTPVFELK ETLMGKYGED SKLIYDLKDQ GGELLSLRYD LTVPFARYLA MNKLTNIKRY HIAKVYRRDN PAMTRGRYRE FYQCDFDIAG NFDPMIPDAE CLKIMCEILS SLQIGDFLVK VNDRRILDGM FAICGVSDSK FRTICSSVDK LDKVSWEEVK NEMVGEKGLA PEVADRIGDY VQQHGGVSLV EQLLQDPKLS QNKQALEGLG DLKLLFEYLT LFGIDDKISF DLSLARGLDY YTGVIYEAVL LQTPAQAGEE PLGVGSVAAG GRYDGLVGMF DPKGRKVPCV GLSIGVERIF SIVEQRLEAL EEKIRTTETQ VLVASAQKKL LEERLKLVSE LWDAGIKAEL LYKKNPKLLN QLQYCEEAGI PLVAIIGEQE LKDGVIKLRS VTSREEVDVR REDLVEEIKR RTGQPLCIC
Genular Protein ID: 3538536841
Symbol: B4E1C5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 395
- Mass: 43879
- Checksum: 2A282CBBC98845F4
- Sequence:
MAERAALEEL VKLQGERVRG LKQQKASAEL IEEEVAKLLK LKAQLGPDES KQKFVLKTPK DFDIAGNFDP MIPDAECLKI MCEILSSLQI GDFLVKVNDR RILDGMFAIC GVSDSKFRTI CSSVDKLDKV SWEEVKNEMV GEKGLAPEVA DRIGDYVQQH GGVSLVEQLL QDPKLSQNKQ ALEGLGDLKL LFEYLTLFGI DDKISFDLSL ARGLDYYTGV IYEAVLLQTP AQAGEEPLGV GSVAAGGRYD GLVGMFDPKG RKVPCVGLSI GVERIFSIVE QRLEALEEKI RTTETQVLVA SAQKKLLEER LKLVSELWDA GIKAELLYKK NPKLLNQLQY CEEAGIPLVA IIGEQELKDG VIKLRSVTSR EEVDVRREDL VEEIKRRTGQ PLCIC
Genular Protein ID: 3011041153
Symbol: B4DDD8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 435
- Mass: 48569
- Checksum: 35F075F833629F5A
- Sequence:
MAERAALEEL VKLQGERVRG LKQQKASAEL IEEEVAKLLK LKAQLGPDES KQKFVLKTPK GTRDYSPRQM AVREKVFDVI IRCFKRHGAE VIDTPVFELK DFDIAGNFDP MIPDAECLKI MCEILSSLQI GDFLVKVNDR RILDGMFAIC GVSDSKFRTI CSSVDKLDKV SWEEVKNEMV GEKGLAPEVA DRIGDYVQQH GGVSLVEQLL QDPKLSQNKQ ALEGLGDLKL LFEYLTLFGI DDKISFDLSL ARGLDYYTGV IYEAVLLQTP AQAGEEPLGV GSVAAGGRYD GLVGMFDPKG RKVPCVGLSI GVERIFSIVE QRLEALEEKI RTTETQVLVA SAQKKLLEER LKLVSELWDA GIKAELLYKK NPKLLNQLQY CEEAGIPLVA IIGEQELKDG VIKLRSVTSR EEVDVRREDL VEEIKRRTGQ PLCIC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.