Details for: DNTTIP2

Gene ID: 30836

Symbol: DNTTIP2

Ensembl ID: ENSG00000067334

Description: deoxynucleotidyltransferase terminal interacting protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 246.0378
    Cell Significance Index: -38.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 131.2473
    Cell Significance Index: -33.2900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 107.8050
    Cell Significance Index: -44.4100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 95.1024
    Cell Significance Index: -44.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 94.4968
    Cell Significance Index: -38.3900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 84.7808
    Cell Significance Index: -43.6100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.5135
    Cell Significance Index: -38.6800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.0378
    Cell Significance Index: -43.2000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.2706
    Cell Significance Index: -35.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.3227
    Cell Significance Index: -44.6800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.4520
    Cell Significance Index: -25.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6868
    Cell Significance Index: 166.8600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3801
    Cell Significance Index: 18.8300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.3226
    Cell Significance Index: 62.1600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.1739
    Cell Significance Index: 33.6500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.1688
    Cell Significance Index: 20.6600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1211
    Cell Significance Index: 30.5200
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.1125
    Cell Significance Index: 11.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0880
    Cell Significance Index: 70.2000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9344
    Cell Significance Index: 151.9700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8450
    Cell Significance Index: 43.9000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8216
    Cell Significance Index: 112.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8104
    Cell Significance Index: 99.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7914
    Cell Significance Index: 55.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7677
    Cell Significance Index: 138.4000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7666
    Cell Significance Index: 338.9300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7658
    Cell Significance Index: 98.9400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7176
    Cell Significance Index: 647.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7151
    Cell Significance Index: 49.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6510
    Cell Significance Index: 48.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5650
    Cell Significance Index: 16.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5640
    Cell Significance Index: 308.0000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.5151
    Cell Significance Index: 9.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4205
    Cell Significance Index: 49.5900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3705
    Cell Significance Index: 256.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.3592
    Cell Significance Index: 9.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3488
    Cell Significance Index: 15.8100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2985
    Cell Significance Index: 15.5500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2764
    Cell Significance Index: 3.1400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2495
    Cell Significance Index: 6.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2411
    Cell Significance Index: 11.2400
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.2311
    Cell Significance Index: 1.6600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2229
    Cell Significance Index: 44.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2022
    Cell Significance Index: 40.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1970
    Cell Significance Index: 25.2600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1242
    Cell Significance Index: 23.6300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1048
    Cell Significance Index: 17.8900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0526
    Cell Significance Index: 1.8500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0478
    Cell Significance Index: 17.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0341
    Cell Significance Index: 0.5700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0277
    Cell Significance Index: 0.5800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0027
    Cell Significance Index: 0.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0138
    Cell Significance Index: -10.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0152
    Cell Significance Index: -11.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0170
    Cell Significance Index: -31.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0171
    Cell Significance Index: -32.2300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0218
    Cell Significance Index: -33.6100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0262
    Cell Significance Index: -16.3800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0322
    Cell Significance Index: -24.3900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0335
    Cell Significance Index: -0.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0341
    Cell Significance Index: -46.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0352
    Cell Significance Index: -22.3400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0434
    Cell Significance Index: -24.5000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0514
    Cell Significance Index: -5.2500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0795
    Cell Significance Index: -36.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0882
    Cell Significance Index: -18.5800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1224
    Cell Significance Index: -35.2100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1285
    Cell Significance Index: -14.7200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1343
    Cell Significance Index: -1.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1482
    Cell Significance Index: -17.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1560
    Cell Significance Index: -9.8400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1795
    Cell Significance Index: -26.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2007
    Cell Significance Index: -10.5400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2416
    Cell Significance Index: -2.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2512
    Cell Significance Index: -7.0200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2567
    Cell Significance Index: -5.9300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2573
    Cell Significance Index: -29.3700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2898
    Cell Significance Index: -16.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3130
    Cell Significance Index: -6.7800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3171
    Cell Significance Index: -8.1000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3803
    Cell Significance Index: -29.1900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4089
    Cell Significance Index: -12.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4275
    Cell Significance Index: -44.5100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4604
    Cell Significance Index: -36.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4692
    Cell Significance Index: -28.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4780
    Cell Significance Index: -24.1600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4835
    Cell Significance Index: -15.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5149
    Cell Significance Index: -34.6300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5181
    Cell Significance Index: -3.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5691
    Cell Significance Index: -12.1200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6077
    Cell Significance Index: -11.8600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6472
    Cell Significance Index: -39.6800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6762
    Cell Significance Index: -18.1200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6874
    Cell Significance Index: -28.1700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7158
    Cell Significance Index: -18.4000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7805
    Cell Significance Index: -19.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8182
    Cell Significance Index: -36.1900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.8423
    Cell Significance Index: -30.9200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9688
    Cell Significance Index: -36.6900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.9759
    Cell Significance Index: -20.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Cellular Expression**: DNTTIP2 is expressed in a wide array of cell types, including those of the nervous system, epithelial tissues, and connective tissue. This suggests a conserved role in maintaining cellular homeostasis across different tissues. 2. **Protein Binding**: DNTTIP2 interacts with various proteins, including deoxynucleotidyltransferases, which are involved in DNA synthesis and repair. This interaction highlights the potential role of DNTTIP2 in regulating gene expression and DNA integrity. 3. **Chromosomal Localization**: The gene is localized to chromosome 11q13.3, an area known for its involvement in various cellular processes, including cell cycle regulation and apoptosis. **Pathways and Functions** 1. **Ribosomal Small Subunit Biogenesis**: DNTTIP2 is involved in the assembly of ribosomal small subunits, which are essential for protein synthesis. This suggests a role in regulating cellular metabolism and energy homeostasis. 2. **RNA Binding and Processing**: DNTTIP2 interacts with RNA-binding proteins, which are involved in RNA processing and transcription. This interaction highlights the potential role of DNTTIP2 in regulating gene expression and RNA stability. 3. **Chromosome and Nucleolus Organization**: DNTTIP2 is involved in the organization of chromosomes and the nucleolus, which are critical for maintaining genome stability and regulating gene expression. **Clinical Significance** 1. **Cancer Association**: The expression of DNTTIP2 in various types of cancer cells, including prostate and breast cancer, suggests a potential role in tumorigenesis and cancer progression. 2. **Neurological Disorders**: The involvement of DNTTIP2 in the assembly of ribosomal small subunits and RNA processing suggests a potential role in neurological disorders, such as neurodegenerative diseases and cancer-associated cognitive decline. 3. **Regenerative Medicine**: The expression of DNTTIP2 in skeletal muscle satellite stem cells and other progenitor cells highlights its potential role in tissue regeneration and repair. In conclusion, DNTTIP2 is a multifaceted gene that plays a critical role in maintaining cellular homeostasis, regulating gene expression, and participating in various cellular processes. Further research is needed to fully elucidate the functions of DNTTIP2 and its potential implications in human disease. As an expert immunologist, I believe that DNTTIP2 is an exciting area of research that holds great promise for advancing our understanding of cellular biology and developing novel therapeutic strategies for various diseases.

Genular Protein ID: 2140801713

Symbol: TDIF2_HUMAN

Name: Deoxynucleotidyltransferase terminal-interacting protein 2

UniProtKB Accession Codes:

Q5QJE6 Q12987 Q53H59 Q5TFJ4 Q6TLI0 Q76MJ8 Q86WX9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 3 Ensembl 1 ExpressionAtlas 1 GO 7 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12786946

Title: Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone.

PubMed ID: 12786946

DOI: 10.1046/j.1365-2443.2003.00656.x

PubMed ID: 15047147

Title: ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor.

PubMed ID: 15047147

DOI: 10.1016/j.bbrc.2004.02.179

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

  • Length: 756
  • Mass: 84469
  • Checksum: 5C58EFABA2B42E4B
  • Sequence:
    • MVVTRSARAK ASIQAASAES SGQKSFAANG IQAHPESSTG SDARTTAESQ TTGKQSLIPR 
TPKARKRKSR TTGSLPKGTE PSTDGETSEA ESNYSVSEHH DTILRVTRRR QILIACSPVS 
SVRKKPKVTP TKESYTEEIV SEAESHVSGI SRIVLPTEKT TGARRSKAKS LTDPSQESHT 
EAISDAETSS SDISFSGIAT RRTRSMQRKL KAQTEKKDSK IVPGNEKQIV GTPVNSEDSD 
TRQTSHLQAR SLSEINKPNF YNNDFDDDFS HRSSENILTV HEQANVESLK ETKQNCKDLD 
EDANGITDEG KEINEKSSQL KNLSELQDTS LQQLVSQRHS TPQNKNAVSV HSNLNSEAVM 
KSLTQTFATV EVGRWNNNKK SPIKASDLTK FGDCGGSDDE EESTVISVSE DMNSEGNVDF 
ECDTKLYTSA PNTSQGKDNS VLLVLSSDES QQSENSENEE DTLCFVENSG QRESLSGDTG 
SLSCDNALFV IDTTPGMSAD KNFYLEEEDK ASEVAIEEEK EEEEDEKSEE DSSDHDENED 
EFSDEEDFLN STKAKLLKLT SSSIDPGLSI KQLGGLYINF NADKLQSNKR TLTQIKEKKK 
NELLQKAVIT PDFEKNHCVP PYSESKYQLQ KKRRKERQKT AGDGWFGMKA PEMTNELKND 
LKALKMRASM DPKRFYKKND RDGFPKYFQI GTIVDNPADF YHSRIPKKQR KRTIVEELLA 
DSEFRRYNRR KYSEIMAEKA ANAAGKKFRK KKKFRN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.