Details for: HK1

Gene ID: 3098

Symbol: HK1

Ensembl ID: ENSG00000156515

Description: hexokinase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.16
    Marker Score: 2608.5
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.15
    Marker Score: 2440
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.07
    Marker Score: 4207.5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.99
    Marker Score: 2091
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.98
    Marker Score: 1866.5
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.95
    Marker Score: 2356
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.86
    Marker Score: 2055
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.85
    Marker Score: 1643
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.83
    Marker Score: 18860
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.82
    Marker Score: 7552
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.81
    Marker Score: 66620
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.76
    Marker Score: 108365
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.74
    Marker Score: 16383
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.7
    Marker Score: 64707
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.69
    Marker Score: 16026
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.67
    Marker Score: 35666
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.67
    Marker Score: 2015
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.66
    Marker Score: 14234
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.65
    Marker Score: 692
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.64
    Marker Score: 24560
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.64
    Marker Score: 32541
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.62
    Marker Score: 6252
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.6
    Marker Score: 3521
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.6
    Marker Score: 12294
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.6
    Marker Score: 7398
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.59
    Marker Score: 12426
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.58
    Marker Score: 1819
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.56
    Marker Score: 2293
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.54
    Marker Score: 6285
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.52
    Marker Score: 1057
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.5
    Marker Score: 2318
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 1.5
    Marker Score: 1564
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.45
    Marker Score: 986
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.43
    Marker Score: 1193
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.43
    Marker Score: 31870
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.4
    Marker Score: 1804
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.38
    Marker Score: 5420
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.37
    Marker Score: 11841
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.37
    Marker Score: 917
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.36
    Marker Score: 4676
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.35
    Marker Score: 2635
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.35
    Marker Score: 803
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.33
    Marker Score: 422
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.33
    Marker Score: 15438
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.32
    Marker Score: 412
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.31
    Marker Score: 766
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.3
    Marker Score: 72799
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.3
    Marker Score: 680
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.3
    Marker Score: 1122
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.28
    Marker Score: 1380
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.28
    Marker Score: 3187
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.28
    Marker Score: 1858
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.28
    Marker Score: 380
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.27
    Marker Score: 9469
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.27
    Marker Score: 19828
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.27
    Marker Score: 4498
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.26
    Marker Score: 1690
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.26
    Marker Score: 427
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.25
    Marker Score: 608
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.25
    Marker Score: 726
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.23
    Marker Score: 336
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.22
    Marker Score: 2167
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.22
    Marker Score: 391.5
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.22
    Marker Score: 7769
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.2
    Marker Score: 1105.5
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.19
    Marker Score: 744
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.19
    Marker Score: 1132
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.18
    Marker Score: 301
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 1.17
    Marker Score: 491
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.15
    Marker Score: 3267
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 1.14
    Marker Score: 247
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.11
    Marker Score: 17819
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.11
    Marker Score: 1570
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.1
    Marker Score: 223
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.09
    Marker Score: 1318
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.09
    Marker Score: 840
  • Cell Name: PP cell (CL0000696)
    Fold Change: 1.09
    Marker Score: 245
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.08
    Marker Score: 2086
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.08
    Marker Score: 540
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.07
    Marker Score: 1093
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.07
    Marker Score: 1202
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.07
    Marker Score: 778
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 1.07
    Marker Score: 351
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.06
    Marker Score: 1324
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.06
    Marker Score: 310
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.05
    Marker Score: 3897
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.05
    Marker Score: 1482
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.04
    Marker Score: 1058
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.04
    Marker Score: 4363
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.04
    Marker Score: 901
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.03
    Marker Score: 679
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.03
    Marker Score: 2584
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 1.03
    Marker Score: 2489
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1
    Marker Score: 573
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1
    Marker Score: 633
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1
    Marker Score: 289
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71605
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47830
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.99
    Marker Score: 577
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.99
    Marker Score: 2815.5

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Other Information

**Key characteristics:** * The HK1 gene is located on chromosome 15q25. * It is a large gene with a length of approximately 13.6 kb. * The protein encoded by HK1 is a transmembrane protein with a molecular weight of approximately 145 kDa. * It is expressed in a wide variety of cell types, including endothelial cells, hepatocytes, and immune cells. **Pathways and functions:** * The HK1 protein is a key regulator of glucose metabolism. It is expressed in many tissues, including muscle, liver, heart, and immune cells. * It is involved in the regulation of blood glucose levels by controlling the uptake of glucose into cells. * It also plays a role in the regulation of insulin signaling, which is a pathway that helps to control blood sugar levels. * The HK1 protein is also involved in the regulation of inflammation and cell survival. **Clinical significance:** * Mutations in the HK1 gene have been linked to a number of human diseases, including diabetes, obesity, and cardiovascular disease. * In diabetes, mutations in HK1 can lead to a decrease in the activity of the protein, which can result in high blood sugar levels. * In obesity, mutations in HK1 can lead to an increase in the activity of the protein, which can also result in high blood sugar levels. * The HK1 gene is also a potential target for the treatment of cardiovascular disease. **Additional points:** * The HK1 protein is a member of the hexokinase family of enzymes. * Hexokinases are involved in the regulation of many cellular processes, including metabolism, cell signaling, and inflammation. * The HK1 protein is a well-characterized target for drug development.

Genular Protein ID: 3118089889

Symbol: HXK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P19367 E9PCK0 O43443 O43444 O75574 Q5VTC3 Q96HC8 Q9NNZ4 Q9NNZ5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CPTAC 2 CTD 1 CarbonylDB 1 ChEBI 56 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 7 EC 5 EMBL 73 EPD 1 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 9 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 25 PDBsum 10 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 7 Rhea 10 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 2 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3207429

Title: Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous.

PubMed ID: 3207429

DOI: 10.1016/s0006-291x(88)80964-1

PubMed ID: 9531504

Title: Structure of the human hexokinase type I gene and nucleotide sequence of the 5' flanking region.

PubMed ID: 9531504

DOI: 10.1042/bj3310607

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10978502

Title: Structure of the 5' region of the human hexokinase type I (HKI) gene and identification of an additional testis-specific HKI mRNA.

PubMed ID: 10978502

DOI: 10.1016/s0167-4781(00)00147-0

PubMed ID: 1985912

Title: Human hexokinase type I microheterogeneity is due to different amino-terminal sequences.

PubMed ID: 1985912

DOI: 10.1016/s0021-9258(18)52464-9

PubMed ID: 1637300

Title: A recombinant human 'mini'-hexokinase is catalytically active and regulated by hexose 6-phosphates.

PubMed ID: 1637300

DOI: 10.1042/bj2850193

PubMed ID: 9028305

Title: Identification of the cDNA for human red blood cell-specific hexokinase isozyme.

PubMed ID: 9028305

PubMed ID: 8706938

Title: Crystallization and preliminary X-ray analysis of human brain hexokinase.

PubMed ID: 8706938

DOI: 10.1016/0014-5793(96)00688-6

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19536174

Title: A mutation in an alternative untranslated exon of hexokinase 1 associated with hereditary motor and sensory neuropathy -- Russe (HMSNR).

PubMed ID: 19536174

DOI: 10.1038/ejhg.2009.99

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22304920

Title: PKCepsilon promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.

PubMed ID: 22304920

DOI: 10.1016/j.cell.2012.01.016

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27374331

Title: Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan.

PubMed ID: 27374331

DOI: 10.1016/j.cell.2016.05.076

PubMed ID: 28675158

Title: Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis.

PubMed ID: 28675158

DOI: 10.1038/cr.2017.85

PubMed ID: 9493266

Title: The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate.

PubMed ID: 9493266

DOI: 10.1016/s0969-2126(98)00006-9

PubMed ID: 9735292

Title: Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate.

PubMed ID: 9735292

DOI: 10.1006/jmbi.1998.2017

PubMed ID: 10574795

Title: Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control.

PubMed ID: 10574795

DOI: 10.1016/s0969-2126(00)80032-5

PubMed ID: 10686099

Title: Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.

PubMed ID: 10686099

DOI: 10.1006/jmbi.1999.3494

PubMed ID: 7655856

Title: Hexokinase mutations that produce nonspherocytic hemolytic anemia.

PubMed ID: 7655856

DOI: 10.1006/bcmd.1995.0002

PubMed ID: 12393545

Title: HK Utrecht: missense mutation in the active site of human hexokinase associated with hexokinase deficiency and severe nonspherocytic hemolytic anemia.

PubMed ID: 12393545

DOI: 10.1182/blood-2002-06-1851

PubMed ID: 25190649

Title: A dominant mutation in hexokinase 1 (HK1) causes retinitis pigmentosa.

PubMed ID: 25190649

DOI: 10.1167/iovs.14-15419

PubMed ID: 25316723

Title: A missense mutation in HK1 leads to autosomal dominant retinitis pigmentosa.

PubMed ID: 25316723

DOI: 10.1167/iovs.14-15520

PubMed ID: 30778173

Title: De novo variants in HK1 associated with neurodevelopmental abnormalities and visual impairment.

PubMed ID: 30778173

DOI: 10.1038/s41431-019-0366-9

PubMed ID: 34193129

Title: Novel homozygous mutations in Pakistani families with Charcot-Marie-Tooth disease.

PubMed ID: 34193129

DOI: 10.1186/s12920-021-01019-5

Sequence Information:

  • Length: 917
  • Mass: 102486
  • Checksum: F29A6837531C0594
  • Sequence:
    • MIAAQLLAYY FTELKDDQVK KIDKYLYAMR LSDETLIDIM TRFRKEMKNG LSRDFNPTAT 
VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVHMESE VYDTPENIVH 
GSGSQLFDHV AECLGDFMEK RKIKDKKLPV GFTFSFPCQQ SKIDEAILIT WTKRFKASGV 
EGADVVKLLN KAIKKRGDYD ANIVAVVNDT VGTMMTCGYD DQHCEVGLII GTGTNACYME 
ELRHIDLVEG DEGRMCINTE WGAFGDDGSL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM 
YLGELVRLIL VKMAKEGLLF EGRITPELLT RGKFNTSDVS AIEKNKEGLH NAKEILTRLG 
VEPSDDDCVS VQHVCTIVSF RSANLVAATL GAILNRLRDN KGTPRLRTTV GVDGSLYKTH 
PQYSRRFHKT LRRLVPDSDV RFLLSESGSG KGAAMVTAVA YRLAEQHRQI EETLAHFHLT 
KDMLLEVKKR MRAEMELGLR KQTHNNAVVK MLPSFVRRTP DGTENGDFLA LDLGGTNFRV 
LLVKIRSGKK RTVEMHNKIY AIPIEIMQGT GEELFDHIVS CISDFLDYMG IKGPRMPLGF 
TFSFPCQQTS LDAGILITWT KGFKATDCVG HDVVTLLRDA IKRREEFDLD VVAVVNDTVG 
TMMTCAYEEP TCEVGLIVGT GSNACYMEEM KNVEMVEGDQ GQMCINMEWG AFGDNGCLDD 
IRTHYDRLVD EYSLNAGKQR YEKMISGMYL GEIVRNILID FTKKGFLFRG QISETLKTRG 
IFETKFLSQI ESDRLALLQV RAILQQLGLN STCDDSILVK TVCGVVSRRA AQLCGAGMAA 
VVDKIRENRG LDRLNVTVGV DGTLYKLHPH FSRIMHQTVK ELSPKCNVSF LLSEDGSGKG 
AALITAVGVR LRTEASS

Genular Protein ID: 2954810854

Symbol: Q59FD4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FD4

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 EC 2 EMBL 2 GO 6 Gene3D 2 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 Rhea 4 SAM 1 SMR 1 SUPFAM 1 UniPathway 2

Sequence Information:

  • Length: 949
  • Mass: 105804
  • Checksum: 54972BD394467EA3
  • Sequence:
    • GAAEQPPEDH GSPGLRRTDR PHACRPATPT ASMIAAQLLA YYFTELKDDQ VKKIDKYLYA 
MRLSDETLID IMTRFRKEMK NGLSRDFNPT ATVKMLPTFV RSIPDGSEKG DFIALDLGGS 
SFRILRVQVN HEKNQNVHME SEVYDTPENI VHGSGSQLFD HVAECLGDFM EKRKIKDKKL 
PVGFTFSFPC QQSKIDEAIL ITWTKRFKAS GVEGADVVKL LNKAIKKRGD YDANIVAVVN 
DTVGTMMTCG YDDQHCEVGL IIGTGTNACY MEELRHIDLV EGDEGRMCIN TEWGAFGDDG 
SLEDIRTEFD REIDRGSLNP GKQLFEKMVS GMYLGELVRL ILVKMAKEGL LFEGRITPEL 
LTRGKFNTSD VSAIEKNKEG LHNAKEILTR LGVEPSDDDC VSVQHVCTIV SFRSANLVAA 
TLGAILNRLR DNKGTPRLRT TVGVDGSLYK THPQYSRRFH KTLRRLVPDS DVRFLLSESG 
SGKGAAMVTA VAYRLAEQHR QIEETLAHFH LTKDMLLEVK KRMRAEMELG LRKQTHNNAV 
VKMLPSFVRR TPDGTENGDF LALDLGGTNF RVLLVKIRSG KKRTVEMHNK IYAIPIEIMQ 
GTGEELFDHI VSCISDFLDY MGIKGPRMPL GFTFSFPCQQ TSLDAGILIT WTKGFKATDC 
VGHDVVTLLR DAIKRREEFD LDVVAVVNDT VGTMMTCAYE EPTCEVGLIV GTGSNACYME 
EMKNVEMVEG DQGQMCINME WGAFGDNGCL DDIRTHYDRL VDEYSLNAGK QRYEKMISGM 
YLGEIVRNIL IDFTKKGFLF RGQISETLKT RGIFETKFLS QIESDRLALL QVRAILQQLG 
LNSTCDDSIL VKTVCGVVSR RAAQLCGAGM AAVVDKIREN RGLDRLNVTV GVDGTLYKLH 
PHFSRIMHQT VKELSPKCNV SFLLSEDGSG KGAALITAVG VRLRTEASS

Genular Protein ID: 3210814083

Symbol: A0A994J753_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J753

Database IDs:

ARBA 11 CDD 1 CTD 1 ChEBI 10 EC 2 EMBL 3 EPD 1 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 Pfam 4 Proteomes 2 RefSeq 2 Rhea 4 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

Sequence Information:

  • Length: 889
  • Mass: 99148
  • Checksum: 68CA5022123C1B0C
  • Sequence:
    • MRLSDETLID IMTRFRKEMK NGLSRDFNPT ATVKMLPTFV RSIPDGSEKG DFIALDLGGS 
SFRILRVQVN HEKNQNVHME SEVYDTPENI VHGSGSQLFD HVAECLGDFM EKRKIKDKKL 
PVGFTFSFPC QQSKIDEAIL ITWTKRFKAS GVEGADVVKL LNKAIKKRGD YDANIVAVVN 
DTVGTMMTCG YDDQHCEVGL IIGTGTNACY MEELRHIDLV EGDEGRMCIN TEWGAFGDDG 
SLEDIRTEFD REIDRGSLNP GKQLFEKMVS GMYLGELVRL ILVKMAKEGL LFEGRITPEL 
LTRGKFNTSD VSAIEKNKEG LHNAKEILTR LGVEPSDDDC VSVQHVCTIV SFRSANLVAA 
TLGAILNRLR DNKGTPRLRT TVGVDGSLYK THPQYSRRFH KTLRRLVPDS DVRFLLSESG 
SGKGAAMVTA VAYRLAEQHR QIEETLAHFH LTKDMLLEVK KRMRAEMELG LRKQTHNNAV 
VKMLPSFVRR TPDGTENGDF LALDLGGTNF RVLLVKIRSG KKRTVEMHNK IYAIPIEIMQ 
GTGEELFDHI VSCISDFLDY MGIKGPRMPL GFTFSFPCQQ TSLDAGILIT WTKGFKATDC 
VGHDVVTLLR DAIKRREEFD LDVVAVVNDT VGTMMTCAYE EPTCEVGLIV GTGSNACYME 
EMKNVEMVEG DQGQMCINME WGAFGDNGCL DDIRTHYDRL VDEYSLNAGK QRYEKMISGM 
YLGEIVRNIL IDFTKKGFLF RGQISETLKT RGIFETKFLS QIESDRLALL QVRAILQQLG 
LNSTCDDSIL VKTVCGVVSR RAAQLCGAGM AAVVDKIREN RGLDRLNVTV GVDGTLYKLH 
PHFSRIMHQT VKELSPKCNV SFLLSEDGSG KGAALITAVG VRLRTEASS

Genular Protein ID: 3277480494

Symbol: P78542_HUMAN

Name: N/A

UniProtKB Accession Codes:

P78542 B1AR61

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 2 GO 1 GeneTree 1 GenomeRNAi 1 HGNC 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 8722688

Title: Testis-specific expression of mRNAs for a unique human type 1 hexokinase lacking the porin-binding domain.

PubMed ID: 8722688

DOI: 10.1002/(SICI)1098-2795(199605)44:1<14::AID-MRD2>3.0.CO;2-W

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 30
  • Mass: 3374
  • Checksum: E84D89B518AD02FC
  • Sequence:
    • MGQICQRESA TAAEKPKLHL LAESEIDKYL

Genular Protein ID: 734820901

Symbol: A8K7J7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K7J7

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 EC 2 EMBL 2 GO 6 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 Rhea 4 SUPFAM 1 UniPathway 2

Sequence Information:

  • Length: 917
  • Mass: 102387
  • Checksum: 0795D838ECB91F3E
  • Sequence:
    • MIAAQLLAYY FTELKDDQVK KIDKYLYAMR LSDETLIDIM TRFRKEMKNG LSRDFNPTAT 
VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVHMESE VYDTPENIVH 
GSGSQLFDHV AECLGDFMEK RKIKDKKLPV GFTFSFPCQQ SKIDEAILIT WTKRFKASGV 
EGADVVKLLN KAIKKRGDYD ANIVAVVNDT VGTMMTCGYD DQHCEVGLII GTGTNACYME 
ELRHIDLVEG DEGRMCINTE WGAFGDDGSL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM 
YLGELVRLIL VKMAKEGLLF EGRITPELLT RGKFNTSDVS AIEKNKEGLH NAKEILTRLG 
VEPSDDDCVS VQHVCTIVSF RSANLVAATL GAILNRLRDN KGTPRLRTTV GVDGSLYKTH 
PQYSRRFHKT LRRLVPDSDV RFLLSESGSG KGAAMVTAVA YRLAEQHRQI EETLAHFHLT 
KDMLLEVKKR MRAEMELGLR KQTHNNAVVK MLPSFVRRTP DGTENGDFLA LDLGGTNFRV 
LLVKIRSGKK RTVEMHNKIY AIPIEIMQGT GEELFDHIVS CISDFLDYMG IKGPRMPLGF 
TFSFPCQQTS LDAGILITWT KGFKATDCVG HDVVTLLRDA IKRREEFDLD VVAVVNDTVG 
TMMTCAYEEP TCEVGLIVGT GSNACYMEEM KNVEMVEGDQ GQMCINMEWG AFGDNGCLDD 
IRTHYDRLVD EYSLNAGKQG YEKMISGMYL GEIVRNILID FTKKGFLFRG QISETLKTRG 
IFETKFLSQI ESDRLALLQV RAILQQLGLN STCDDSILVK TVCGVVSRRA AQLCGAGMAA 
VVDKIRENRG LDRLNVTVGV DGTLYKLHPH FSRIMHQTVK ELSPKCNVSF LLSEDGSGKG 
AALITAVGVR LRTEASS

Genular Protein ID: 2655623070

Symbol: B3KXY9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KXY9

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 EC 2 EMBL 2 GO 6 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 5 KEGG 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 5 Rhea 4 SUPFAM 1 UniPathway 2

Sequence Information:

  • Length: 952
  • Mass: 106251
  • Checksum: A94B1EA9F55547E7
  • Sequence:
    • MGQICQRESR QGLAMLPRLF LNPWRQVILL PQPPKVLGLQ ATAAEKPKLH LLAESEIDKY 
LYAMRLSDET LIDIMTRFRK EMKNGLSRDF NPTATVKMLP TFVRPIPDGS EKGDFIALDL 
GGSSFRILRV QVNHEKNQNV HMESEVYDTP ENIVHGSGSQ LFDHVAECLG DFMEKRKIKD 
KKLPVGFTFS FPCQQSKIDE AILITWTKRF KASGVEGADV VKLLNKAIKK RGDYDANIVA 
VVNDTVGTMM TCGYDDQHCE VGLIIGTGTN ACYMEELRHI DLVEGDEGRM CINTEWGAFG 
DDGSLEDIRT EFDREIDRGS LNPGKQLFEK MVSGMYLGEL VRLILVKMAK EGLLFEGRIT 
PELLTRGKFN TSDVSAIEKN KEGLHNAKEI LTRLGVEPSD DDCVSVQHVC TIVSFRSANL 
VAATLGAILN RLRDNKGTPR LRTTVGVDGS LYKTHPQYSR RFHKTLRRLV PDSDVRFLLS 
ESGSGKGAAM VTAVAYRLAE QHRQIEETLA HFHLTKDMLL EVKKRMRAEM ELGLRKQTHN 
NAVVKMLPSF VRRTPDGTEN GDFLALDLGG TNFRVLLVKI RSGKKRTVEM HNKIYAIPIE 
IMQGTGEELF DHIVSCISDF LDYMGIKGPR MPLGFTFSFP CQQTSLDAGI LITWTKGFKA 
TDCVGHDVVT LLRDAIKRRE EFDLDVVAVV NDTVGTMMTC AYGEPTCEVG LIVGTGSNAC 
YMEEMKNVEM VEGDQGQMCI NMEWGAFGDN GCLDDIRTHY DRLVDEYSLN AGKQRYEKMI 
SGMYLGEIVR NILIDFTKKG FLFRGQISET LKTRGIFETK FLSQIESDRL ALLQVRAILQ 
QLGLNSTCDD SILVKTVCGV VSRRAAQLCG AGMAAVVDKI RENRGLDRLN VTVGVDGTLY 
KLHPHFSRIM HQTVKELSPK CNVSFLLSED GSGKGAALIT AVGVRLRTEA SS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.