Details for: HNRNPD

Gene ID: 3184

Symbol: HNRNPD

Ensembl ID: ENSG00000138668

Description: heterogeneous nuclear ribonucleoprotein D

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 576.5526
    Cell Significance Index: -89.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 360.7427
    Cell Significance Index: -91.5000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 266.6298
    Cell Significance Index: -109.8400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 231.2111
    Cell Significance Index: -109.1600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 199.3059
    Cell Significance Index: -102.5200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 162.6623
    Cell Significance Index: -109.1500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 83.3282
    Cell Significance Index: -102.7400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 35.2949
    Cell Significance Index: -94.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 26.9662
    Cell Significance Index: -106.4100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 24.3631
    Cell Significance Index: -74.8300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 19.0808
    Cell Significance Index: -41.7600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.9897
    Cell Significance Index: 106.5300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.4144
    Cell Significance Index: 95.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.8789
    Cell Significance Index: 395.3500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.5868
    Cell Significance Index: 166.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.2829
    Cell Significance Index: 128.1100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.1931
    Cell Significance Index: 76.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.1226
    Cell Significance Index: 261.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.1043
    Cell Significance Index: 379.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.8684
    Cell Significance Index: 87.8200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.8594
    Cell Significance Index: 369.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8065
    Cell Significance Index: 986.5500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.7837
    Cell Significance Index: 788.6000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7698
    Cell Significance Index: 355.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.7420
    Cell Significance Index: 50.1900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.6232
    Cell Significance Index: 114.8000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.4891
    Cell Significance Index: 175.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4306
    Cell Significance Index: 66.7000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4013
    Cell Significance Index: 227.9100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.3059
    Cell Significance Index: 78.4000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.2409
    Cell Significance Index: 13.4900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0962
    Cell Significance Index: 393.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0809
    Cell Significance Index: 29.4200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.9837
    Cell Significance Index: 20.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9582
    Cell Significance Index: 43.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.9581
    Cell Significance Index: 123.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8987
    Cell Significance Index: 811.4700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8618
    Cell Significance Index: 596.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7610
    Cell Significance Index: 39.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7565
    Cell Significance Index: 46.5000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6872
    Cell Significance Index: 19.7000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5799
    Cell Significance Index: 43.2200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5533
    Cell Significance Index: 70.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4824
    Cell Significance Index: 82.3800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3194
    Cell Significance Index: 7.3800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2331
    Cell Significance Index: 12.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2268
    Cell Significance Index: 7.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1950
    Cell Significance Index: 19.2900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1083
    Cell Significance Index: 6.8200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1024
    Cell Significance Index: 192.7400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1012
    Cell Significance Index: 2.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0982
    Cell Significance Index: 18.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0784
    Cell Significance Index: 49.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0399
    Cell Significance Index: 3.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0303
    Cell Significance Index: 13.7700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0291
    Cell Significance Index: 44.7400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0207
    Cell Significance Index: 38.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0168
    Cell Significance Index: 12.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0238
    Cell Significance Index: -32.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0283
    Cell Significance Index: -21.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0294
    Cell Significance Index: -21.8000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0642
    Cell Significance Index: -40.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1046
    Cell Significance Index: -1.7500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1199
    Cell Significance Index: -67.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1747
    Cell Significance Index: -17.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2416
    Cell Significance Index: -50.8800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.3026
    Cell Significance Index: -32.9100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3217
    Cell Significance Index: -92.5600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3399
    Cell Significance Index: -49.4200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4537
    Cell Significance Index: -51.7900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4724
    Cell Significance Index: -9.2200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5004
    Cell Significance Index: -58.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5180
    Cell Significance Index: -34.8300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6267
    Cell Significance Index: -71.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6372
    Cell Significance Index: -18.7200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7058
    Cell Significance Index: -18.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.8458
    Cell Significance Index: -11.5400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8626
    Cell Significance Index: -89.8200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9120
    Cell Significance Index: -72.2300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.0212
    Cell Significance Index: -6.1700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1305
    Cell Significance Index: -10.4100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.1807
    Cell Significance Index: -20.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.1953
    Cell Significance Index: -52.8700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.2278
    Cell Significance Index: -31.5600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.2812
    Cell Significance Index: -23.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.3088
    Cell Significance Index: -41.9200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.3968
    Cell Significance Index: -70.5900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.3987
    Cell Significance Index: -15.8900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.5108
    Cell Significance Index: -57.2100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.5599
    Cell Significance Index: -37.4100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.6485
    Cell Significance Index: -28.2500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.6710
    Cell Significance Index: -41.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.7415
    Cell Significance Index: -106.7700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.8337
    Cell Significance Index: -49.1400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.8655
    Cell Significance Index: -39.7300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.8896
    Cell Significance Index: -31.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.9153
    Cell Significance Index: -41.5000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.9191
    Cell Significance Index: -51.3400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -2.1225
    Cell Significance Index: -16.3600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.3285
    Cell Significance Index: -68.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** HNRNPD is a 55-kDa protein that belongs to the hnRNP family, which consists of multiple subtypes. The protein is characterized by its ability to bind to specific RNA sequences, including AU-rich elements (AREs) and 3'-untranslated regions (3'-UTRs). HNRNPD is highly expressed in cells that require rapid changes in gene expression, such as neurons and hematopoietic stem cells. **Pathways and Functions:** HNRNPD is involved in various cellular processes, including: 1. **mRNA Stabilization:** HNRNPD binds to 3'-UTRs and AU-rich elements, promoting the stability of mRNAs and regulating their translation. 2. **Gene Expression Regulation:** HNRNPD modulates gene expression by regulating mRNA localization, translation, and degradation. 3. **Signaling Pathways:** HNRNPD is involved in various signaling pathways, including the cellular response to amino acid stimulus, estradiol stimulus, and nitric oxide. 4. **Circadian Regulation:** HNRNPD regulates circadian rhythm by controlling the expression of clock genes. 5. **Telomere Maintenance:** HNRNPD is involved in telomere capping and maintenance, ensuring the stability of telomeres. **Clinical Significance:** HNRNPD has been implicated in various diseases, including: 1. **Neurological Disorders:** HNRNPD is involved in the regulation of gene expression in neurons, making it a potential target for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. 2. **Cancer:** HNRNPD has been associated with cancer progression and metastasis, suggesting its potential as a therapeutic target. 3. **Cardiovascular Disease:** HNRNPD is involved in the regulation of gene expression in cardiac cells, making it a potential target for the treatment of cardiovascular disease. **Significantly Expressed Cells:** HNRNPD is highly expressed in multiple cell types, including: 1. **GABAergic Neuron:** HNRNPD is involved in the regulation of gene expression in GABAergic neurons, which are critical for neuronal function. 2. **Erythroid Progenitor Cell:** HNRNPD regulates the expression of genes involved in erythropoiesis. 3. **Cord Blood Hematopoietic Stem Cell:** HNRNPD is involved in the regulation of gene expression in hematopoietic stem cells. 4. **Basal Epithelial Cell:** HNRNPD regulates the expression of genes involved in epithelial homeostasis. In conclusion, HNRNPD is a multifaceted protein that plays a critical role in various cellular processes, including mRNA stabilization, gene expression regulation, and involvement in signaling pathways. Its clinical significance is evident in its involvement in neurological disorders, cancer, and cardiovascular disease. Further research is needed to fully elucidate the functions of HNRNPD and its potential as a therapeutic target.

Genular Protein ID: 3708939482

Symbol: HNRPD_HUMAN

Name: Heterogeneous nuclear ribonucleoprotein D0

UniProtKB Accession Codes:

Q14103 A8K9J2 P07029 Q01858 Q14100 Q14101 Q14102 Q4W5A1 Q9UCE8 Q9UCE9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 16 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 43 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 3 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7673195

Title: The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family.

PubMed ID: 7673195

DOI: 10.1074/jbc.270.38.22167

PubMed ID: 9615222

Title: The human HNRPD locus maps to 4q21 and encodes a highly conserved protein.

PubMed ID: 9615222

DOI: 10.1006/geno.1998.5237

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3754960

Title: A cDNA clone of the hnRNP C proteins and its homology with the single-stranded DNA binding protein UP2.

PubMed ID: 3754960

DOI: 10.1093/nar/14.10.4077

PubMed ID: 10024518

Title: Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specific DNA-binding protein.

PubMed ID: 10024518

DOI: 10.1042/bj3380417

PubMed ID: 1433497

Title: Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II.

PubMed ID: 1433497

DOI: 10.1128/jvi.66.12.6841-6848.1992

PubMed ID: 8321232

Title: Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.

PubMed ID: 8321232

DOI: 10.1128/mcb.13.7.4301-4310.1993

PubMed ID: 9521873

Title: Structure and genomic organization of the human AUF1 gene: alternative pre-mRNA splicing generates four protein isoforms.

PubMed ID: 9521873

DOI: 10.1006/geno.1997.5142

PubMed ID: 11051545

Title: A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex.

PubMed ID: 11051545

DOI: 10.1016/s0092-8674(00)00102-1

PubMed ID: 12674497

Title: Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D).

PubMed ID: 12674497

DOI: 10.1515/bc.2003.004

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15782174

Title: Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.

PubMed ID: 15782174

DOI: 10.1038/nmeth715

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21515746

Title: Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs.

PubMed ID: 21515746

DOI: 10.1096/fj.10-178715

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 24423872

Title: AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation.

PubMed ID: 24423872

DOI: 10.1093/nar/gkt1379

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 10080887

Title: Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0.

PubMed ID: 10080887

DOI: 10.1006/jmbi.1999.2616

Sequence Information:

  • Length: 355
  • Mass: 38434
  • Checksum: D0B6EA177BEF789E
  • Sequence:
    • MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS 
AESEGAKIDA SKNEEDEGHS NSSPRHSEAA TAQREEWKMF IGGLSWDTTK KDLKDYFSKF 
GEVVDCTLKL DPITGRSRGF GFVLFKESES VDKVMDQKEH KLNGKVIDPK RAKAMKTKEP 
VKKIFVGGLS PDTPEEKIRE YFGGFGEVES IELPMDNKTN KRRGFCFITF KEEEPVKKIM 
EKKYHNVGLS KCEIKVAMSK EQYQQQQQWG SRGGFAGRAR GRGGGPSQNW NQGYSNYWNQ 
GYGNYGYNSQ GYGGYGGYDY TGYNNYYGYG DYSNQQSGYG KVSRRGGHQN SYKPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.