Details for: HSP90AA1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 1520.0081
Cell Significance Index: -236.4300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 977.8296
Cell Significance Index: -248.0200 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 705.4295
Cell Significance Index: -290.6000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 616.4288
Cell Significance Index: -291.0300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 538.6819
Cell Significance Index: -277.0900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 435.0527
Cell Significance Index: -291.9300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 228.6213
Cell Significance Index: -281.8800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 82.4362
Cell Significance Index: -220.8400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 78.8779
Cell Significance Index: -242.2700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 74.6798
Cell Significance Index: -294.6900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 41.0402
Cell Significance Index: -89.8200 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 17.1927
Cell Significance Index: 182.6700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 10.0132
Cell Significance Index: 525.7300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 9.8299
Cell Significance Index: 281.7800 - Cell Name: odontoblast (CL0000060)
Fold Change: 8.9261
Cell Significance Index: 1144.2800 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 8.6094
Cell Significance Index: 66.3600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 8.5378
Cell Significance Index: 401.2700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 7.3054
Cell Significance Index: 253.8600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 6.2367
Cell Significance Index: 1124.2800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 6.0719
Cell Significance Index: 746.5900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 5.7229
Cell Significance Index: 785.9200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 5.4136
Cell Significance Index: 2956.5000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 4.9238
Cell Significance Index: 129.4700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 4.3923
Cell Significance Index: 1941.9400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 4.3593
Cell Significance Index: 281.2400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.3228
Cell Significance Index: 201.5500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 4.2424
Cell Significance Index: 500.3100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.7323
Cell Significance Index: 101.5900 - Cell Name: lactocyte (CL0002325)
Fold Change: 3.6887
Cell Significance Index: 476.5600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 3.5934
Cell Significance Index: 95.9500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.5530
Cell Significance Index: 705.1000 - Cell Name: peg cell (CL4033014)
Fold Change: 3.5384
Cell Significance Index: 81.7500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.8259
Cell Significance Index: 199.8600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.6323
Cell Significance Index: 24.2400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.3960
Cell Significance Index: 178.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.1404
Cell Significance Index: 429.3700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.9809
Cell Significance Index: 710.5200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.7913
Cell Significance Index: 51.6100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.7525
Cell Significance Index: 98.3400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.5332
Cell Significance Index: 261.8100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7566
Cell Significance Index: 74.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.7565
Cell Significance Index: 554.6600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.5060
Cell Significance Index: 383.0200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2169
Cell Significance Index: 7.6200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1781
Cell Significance Index: 28.9600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0960
Cell Significance Index: 180.6800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0747
Cell Significance Index: -101.6100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1126
Cell Significance Index: -11.5000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1315
Cell Significance Index: -242.5400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1319
Cell Significance Index: -2.7600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1446
Cell Significance Index: -222.5400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1503
Cell Significance Index: -111.3600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1895
Cell Significance Index: -120.3500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.2713
Cell Significance Index: -169.4300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3019
Cell Significance Index: -19.0300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3338
Cell Significance Index: -17.3400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.3902
Cell Significance Index: -220.0400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3908
Cell Significance Index: -24.0200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.4021
Cell Significance Index: -278.1300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.4256
Cell Significance Index: -193.1600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.4619
Cell Significance Index: -87.9100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4905
Cell Significance Index: -56.0000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.6882
Cell Significance Index: -144.9600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.6919
Cell Significance Index: -20.3200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.7338
Cell Significance Index: -12.2800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.8933
Cell Significance Index: -257.0300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.9747
Cell Significance Index: -17.2300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -1.0339
Cell Significance Index: -112.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.4373
Cell Significance Index: -208.9400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.4626
Cell Significance Index: -167.5700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -1.6335
Cell Significance Index: -190.3700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.6431
Cell Significance Index: -130.1300 - Cell Name: kidney cell (CL1000497)
Fold Change: -1.7040
Cell Significance Index: -13.6100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.7736
Cell Significance Index: -119.2600 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -2.0112
Cell Significance Index: -23.9800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -2.1214
Cell Significance Index: -39.2100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -2.3323
Cell Significance Index: -65.1800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -2.4856
Cell Significance Index: -63.5000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -2.7223
Cell Significance Index: -208.9100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.7550
Cell Significance Index: -286.8600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -3.0679
Cell Significance Index: -139.0600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -3.1300
Cell Significance Index: -53.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -3.3344
Cell Significance Index: -72.2400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -3.4744
Cell Significance Index: -240.2700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -3.5718
Cell Significance Index: -214.4300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -3.6081
Cell Significance Index: -159.6000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -3.6758
Cell Significance Index: -47.0800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -3.8714
Cell Significance Index: -52.8200 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -3.9160
Cell Significance Index: -33.6500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -4.6201
Cell Significance Index: -174.9500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -4.7154
Cell Significance Index: -289.1000 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -4.8237
Cell Significance Index: -52.4400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -4.8949
Cell Significance Index: -130.9400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -4.9101
Cell Significance Index: -140.1200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -5.2497
Cell Significance Index: -168.1400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -5.4531
Cell Significance Index: -61.9500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -5.5540
Cell Significance Index: -163.5900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -5.6754
Cell Significance Index: -141.8700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -6.4845
Cell Significance Index: -238.0400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -6.8630
Cell Significance Index: -224.7000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2723957671
Symbol: HS90A_HUMAN
Name: Heat shock 86 kDa
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2780322
Title: Nucleotide sequence of a full-length cDNA for 90 kDa heat-shock protein from human peripheral blood lymphocytes.
PubMed ID: 2780322
PubMed ID: 1368637
Title: Molecular cloning of cDNA encoding a human heat-shock protein whose expression is induced by adenovirus type 12 E1A in HeLa cells.
PubMed ID: 1368637
PubMed ID: 2527334
Title: Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein.
PubMed ID: 2527334
PubMed ID: 16269234
Title: The HSP90 family of genes in the human genome: insights into their divergence and evolution.
PubMed ID: 16269234
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 2469626
Title: Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.
PubMed ID: 2469626
PubMed ID: 2591742
Title: Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.
PubMed ID: 2591742
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2492519
Title: Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.
PubMed ID: 2492519
PubMed ID: 10409742
Title: Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
PubMed ID: 10409742
PubMed ID: 15937123
Title: S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities.
PubMed ID: 15937123
PubMed ID: 2507541
Title: The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein, hsp90 alpha at two NH2-terminal threonine residues.
PubMed ID: 2507541
PubMed ID: 8289821
Title: The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo.
PubMed ID: 8289821
PubMed ID: 7588731
Title: Mechanism of dimer formation of the 90-kDa heat-shock protein.
PubMed ID: 7588731
PubMed ID: 9195923
Title: Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin.
PubMed ID: 9195923
PubMed ID: 9660753
Title: Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90.
PubMed ID: 9660753
PubMed ID: 10508479
Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.
PubMed ID: 10508479
DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5
PubMed ID: 11274138
Title: Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.
PubMed ID: 11274138
PubMed ID: 11583998
Title: Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.
PubMed ID: 11583998
PubMed ID: 11276205
PubMed ID: 12526792
Title: Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70.
PubMed ID: 12526792
PubMed ID: 12853476
Title: Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.
PubMed ID: 12853476
DOI: 10.1093/emboj/cdg362
PubMed ID: 12604615
Title: Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone.
PubMed ID: 12604615
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 15235609
Title: SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
PubMed ID: 15235609
DOI: 10.1038/ncb1151
PubMed ID: 15708368
Title: Small glutamine-rich tetratricopeptide repeat-containing protein is composed of three structural units with distinct functions.
PubMed ID: 15708368
PubMed ID: 15383005
Title: Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.
PubMed ID: 15383005
DOI: 10.1042/bj20040690
PubMed ID: 15577939
Title: Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.
PubMed ID: 15577939
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16807684
Title: Phosphoproteomic analysis of the human pituitary.
PubMed ID: 16807684
PubMed ID: 16531226
Title: Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.
PubMed ID: 16531226
PubMed ID: 17947705
Title: Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase.
PubMed ID: 17947705
PubMed ID: 18400751
Title: Conserved conformational changes in the ATPase cycle of human Hsp90.
PubMed ID: 18400751
PubMed ID: 19367720
Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
PubMed ID: 19367720
DOI: 10.1021/pr800500r
PubMed ID: 18088087
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 19875381
Title: A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.
PubMed ID: 19875381
PubMed ID: 16139798
Title: Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
PubMed ID: 16139798
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 17028174
Title: Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
PubMed ID: 17028174
PubMed ID: 18256191
Title: The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis.
PubMed ID: 18256191
DOI: 10.1242/dev.018150
PubMed ID: 19696785
Title: Hsp90 is regulated by a switch point in the C-terminal domain.
PubMed ID: 19696785
PubMed ID: 20628368
Title: Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.
PubMed ID: 20628368
DOI: 10.1038/cr.2010.103
PubMed ID: 20353823
Title: Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response.
PubMed ID: 20353823
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22066472
Title: Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion.
PubMed ID: 22066472
PubMed ID: 23569206
Title: Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites.
PubMed ID: 23569206
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24613385
Title: Hsp70 and Hsp90 oppositely regulate TGF-beta signaling through CHIP/Stub1.
PubMed ID: 24613385
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24681825
Title: The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.
PubMed ID: 24681825
PubMed ID: 25973397
Title: Hsp90, the concertmaster: tuning transcription.
PubMed ID: 25973397
PubMed ID: 25609812
Title: Tom70 mediates Sendai virus-induced apoptosis on mitochondria.
PubMed ID: 25609812
DOI: 10.1128/jvi.02959-14
PubMed ID: 25738358
Title: C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis.
PubMed ID: 25738358
PubMed ID: 26517842
Title: Client proteins and small molecule inhibitors display distinct binding preferences for constitutive and stress-induced HSP90 isoforms and their conformationally restricted mutants.
PubMed ID: 26517842
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27295069
Title: Hsp90: Friends, clients and natural foes.
PubMed ID: 27295069
PubMed ID: 26991466
Title: Review: The HSP90 molecular chaperone-an enigmatic ATPase.
PubMed ID: 26991466
DOI: 10.1002/bip.22835
PubMed ID: 27353360
Title: The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
PubMed ID: 27353360
DOI: 10.1038/ncomms12037
PubMed ID: 26754925
Title: IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis.
PubMed ID: 26754925
DOI: 10.1038/srep19174
PubMed ID: 29127155
Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
PubMed ID: 29127155
PubMed ID: 30559449
Title: Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
PubMed ID: 30559449
PubMed ID: 29743370
Title: Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex.
PubMed ID: 29743370
DOI: 10.1128/jvi.00402-18
PubMed ID: 9108479
Title: Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
PubMed ID: 9108479
PubMed ID: 9817749
Title: In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis.
PubMed ID: 9817749
PubMed ID: 16307917
Title: Chaperoned ubiquitylation -- crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
PubMed ID: 16307917
Sequence Information:
- Length: 732
- Mass: 84660
- Checksum: 969F65FCC0BC86FD
- Sequence:
MPEETQTQDQ PMEEEEVETF AFQAEIAQLM SLIINTFYSN KEIFLRELIS NSSDALDKIR YESLTDPSKL DSGKELHINL IPNKQDRTLT IVDTGIGMTK ADLINNLGTI AKSGTKAFME ALQAGADISM IGQFGVGFYS AYLVAEKVTV ITKHNDDEQY AWESSAGGSF TVRTDTGEPM GRGTKVILHL KEDQTEYLEE RRIKEIVKKH SQFIGYPITL FVEKERDKEV SDDEAEEKED KEEEKEKEEK ESEDKPEIED VGSDEEEEKK DGDKKKKKKI KEKYIDQEEL NKTKPIWTRN PDDITNEEYG EFYKSLTNDW EDHLAVKHFS VEGQLEFRAL LFVPRRAPFD LFENRKKKNN IKLYVRRVFI MDNCEELIPE YLNFIRGVVD SEDLPLNISR EMLQQSKILK VIRKNLVKKC LELFTELAED KENYKKFYEQ FSKNIKLGIH EDSQNRKKLS ELLRYYTSAS GDEMVSLKDY CTRMKENQKH IYYITGETKD QVANSAFVER LRKHGLEVIY MIEPIDEYCV QQLKEFEGKT LVSVTKEGLE LPEDEEEKKK QEEKKTKFEN LCKIMKDILE KKVEKVVVSN RLVTSPCCIV TSTYGWTANM ERIMKAQALR DNSTMGYMAA KKHLEINPDH SIIETLRQKA EADKNDKSVK DLVILLYETA LLSSGFSLED PQTHANRIYR MIKLGLGIDE DDPTADDTSA AVTEEMPPLE GDDDTSRMEE VD
Genular Protein ID: 2236158157
Symbol: Q86SX1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 262
- Mass: 29031
- Checksum: 886BBF5DEE3BFF29
- Sequence:
MPPCSGGDGS TPPGPSLRDR DCPAQSAEYP RDRLDPRPGS PSEASSPPFL RSRAPVNWYQ EKAQVFLWHL MVSGSTTLLC LWKQPFHVSA FPVTASLAFR QSQGAGQHLY KDLQPFILLR LLMPEETQTQ DQPMEEEEVE TFAFQAEIAQ LMSLIINTFY SNKEIFLREL ISNSSDALDK IRYESLTDPS KLDSGKELHI NLIPNKQDRT LTIVDTGIGM TKADLINNLG TIAKSGTKAF MEALQAGADI SMIGQFGVGF YS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.