Details for: KCNN3

Gene ID: 3782

Symbol: KCNN3

Ensembl ID: ENSG00000143603

Description: potassium calcium-activated channel subfamily N member 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 166.5753
    Cell Significance Index: -25.9100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 102.4667
    Cell Significance Index: -25.9900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 20.9983
    Cell Significance Index: -25.8900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.5914
    Cell Significance Index: -26.0100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.4099
    Cell Significance Index: -11.8400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 5.1003
    Cell Significance Index: 71.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.9799
    Cell Significance Index: 131.8100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.9764
    Cell Significance Index: 112.7100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.7101
    Cell Significance Index: 77.5200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1704
    Cell Significance Index: 222.7400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8228
    Cell Significance Index: 21.1500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.7694
    Cell Significance Index: 12.4200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7506
    Cell Significance Index: 74.2500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7482
    Cell Significance Index: 675.6100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.7231
    Cell Significance Index: 48.6200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7032
    Cell Significance Index: 252.2300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.4309
    Cell Significance Index: 7.4500
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.4301
    Cell Significance Index: 4.4900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3523
    Cell Significance Index: 70.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3268
    Cell Significance Index: 53.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3027
    Cell Significance Index: 9.7000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2717
    Cell Significance Index: 187.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.2139
    Cell Significance Index: 31.1000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1968
    Cell Significance Index: 4.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1797
    Cell Significance Index: 19.5500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1763
    Cell Significance Index: 325.0600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.1396
    Cell Significance Index: 87.1500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1288
    Cell Significance Index: 198.2500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1285
    Cell Significance Index: 7.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0488
    Cell Significance Index: 3.3800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0441
    Cell Significance Index: 5.2100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0211
    Cell Significance Index: 4.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0089
    Cell Significance Index: 16.7300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0031
    Cell Significance Index: -0.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0090
    Cell Significance Index: -0.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0136
    Cell Significance Index: -10.0400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0163
    Cell Significance Index: -11.9300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0221
    Cell Significance Index: -30.0500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0250
    Cell Significance Index: -13.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0314
    Cell Significance Index: -17.7200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0318
    Cell Significance Index: -20.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0391
    Cell Significance Index: -29.5600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0413
    Cell Significance Index: -18.2500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0419
    Cell Significance Index: -19.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0567
    Cell Significance Index: -11.9500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0696
    Cell Significance Index: -20.0300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0771
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0936
    Cell Significance Index: -15.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0937
    Cell Significance Index: -16.9000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0965
    Cell Significance Index: -2.3600
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: -0.1116
    Cell Significance Index: -1.2400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1199
    Cell Significance Index: -15.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1624
    Cell Significance Index: -19.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1881
    Cell Significance Index: -25.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1940
    Cell Significance Index: -11.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2154
    Cell Significance Index: -27.8300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2209
    Cell Significance Index: -13.2600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2256
    Cell Significance Index: -25.7500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2325
    Cell Significance Index: -27.0900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2327
    Cell Significance Index: -17.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2408
    Cell Significance Index: -25.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2497
    Cell Significance Index: -25.5100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2573
    Cell Significance Index: -18.2000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2945
    Cell Significance Index: -15.3400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3072
    Cell Significance Index: -35.2000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3218
    Cell Significance Index: -6.4600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3235
    Cell Significance Index: -25.6200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3477
    Cell Significance Index: -5.3800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3554
    Cell Significance Index: -11.6400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.3710
    Cell Significance Index: -2.3300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3719
    Cell Significance Index: -8.9200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3740
    Cell Significance Index: -8.0800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3746
    Cell Significance Index: -27.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3894
    Cell Significance Index: -21.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4023
    Cell Significance Index: -11.4800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4190
    Cell Significance Index: -4.7600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.4262
    Cell Significance Index: -6.1300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4469
    Cell Significance Index: -7.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4470
    Cell Significance Index: -28.8400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4576
    Cell Significance Index: -28.8400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4613
    Cell Significance Index: -10.1000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4703
    Cell Significance Index: -6.7400
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.4806
    Cell Significance Index: -5.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4845
    Cell Significance Index: -13.5400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5167
    Cell Significance Index: -18.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5263
    Cell Significance Index: -27.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5330
    Cell Significance Index: -27.6900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5428
    Cell Significance Index: -8.1800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.5537
    Cell Significance Index: -26.0300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.5755
    Cell Significance Index: -6.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5796
    Cell Significance Index: -18.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.7056
    Cell Significance Index: -14.7700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7107
    Cell Significance Index: -26.0900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.7395
    Cell Significance Index: -34.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7448
    Cell Significance Index: -25.8800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7578
    Cell Significance Index: -16.1400
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.7712
    Cell Significance Index: -7.6300
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.7740
    Cell Significance Index: -9.0300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.7751
    Cell Significance Index: -10.3400
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.8033
    Cell Significance Index: -5.8400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Channel Type:** SK channels are small conductance calcium-activated potassium channels, which are characterized by their ability to respond to increases in intracellular calcium concentrations. 2. **Subcellular Localization:** These channels are primarily localized to the plasma membrane, where they regulate the flow of potassium ions in and out of the cell. 3. **Cellular Expression:** KCNN3 is widely expressed in various cell types, including retinal bipolar neurons, astrocytes, dopaminergic neurons, and endothelial cells. 4. **Protein Structure:** The KCNN3 protein consists of six transmembrane domains and two pore-forming domains, which facilitate the channel's function. **Pathways and Functions:** 1. **Neuronal Excitability:** SK channels modulate neuronal excitability by regulating the flow of potassium ions, which affects the action potential threshold and neuronal firing. 2. **Muscle Relaxation:** SK channels contribute to muscle relaxation by facilitating the efflux of potassium ions, which counteracts muscle contraction. 3. **Immune System Modulation:** SK channels play a role in regulating immune responses, particularly in the context of T-cell activation and cytokine production. 4. **Inflammation:** KCNN3 has been implicated in the regulation of inflammatory responses, including the production of pro-inflammatory cytokines. **Clinical Significance:** 1. **Neurological Disorders:** Abnormalities in SK channel function have been linked to various neurological disorders, including epilepsy, migraines, and Parkinson's disease. 2. **Immune System Dysregulation:** Dysregulation of SK channels has been implicated in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cardiac Arrhythmias:** Alterations in SK channel function have been associated with cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. 4. **Pain Modulation:** SK channels have been shown to play a role in pain modulation, particularly in the context of neuropathic pain. In conclusion, the KCNN3 gene encodes for a critical component of the SK channel family, which regulates various cellular processes, including neuronal excitability, muscle relaxation, and immune system modulation. Understanding the roles of KCNN3 in these processes has significant implications for the treatment and management of neurological disorders, immune system dysregulation, and cardiac arrhythmias.

Genular Protein ID: 399626918

Symbol: KCNN3_HUMAN

Name: KCa2.3

UniProtKB Accession Codes:

Q9UGI6 B1ANX0 O43517 Q86VF9 Q8WXG7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 8 DrugCentral 1 EMBL 11 Ensembl 3 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 3 Rhea 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9491810

Title: Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

PubMed ID: 9491810

DOI: 10.1038/sj.mp.4000353

PubMed ID: 11501944

Title: Genomic organization and promoter analysis of human KCNN3 gene.

PubMed ID: 11501944

DOI: 10.1007/s100380170046

PubMed ID: 12808432

Title: Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia.

PubMed ID: 12808432

DOI: 10.1038/sj.mp.4001271

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20689065

Title: Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.

PubMed ID: 20689065

DOI: 10.1161/circresaha.109.215269

PubMed ID: 20562108

Title: Allosteric block of KCa2 channels by apamin.

PubMed ID: 20562108

DOI: 10.1074/jbc.m110.110072

PubMed ID: 31155282

Title: Gain-of-function mutations in KCNN3 encoding the small-conductance Ca2+-activated K+ channel SK3 cause Zimmermann-Laband syndrome.

PubMed ID: 31155282

DOI: 10.1016/j.ajhg.2019.04.012

PubMed ID: 36502918

Title: Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function.

PubMed ID: 36502918

DOI: 10.1016/j.jbc.2022.102783

PubMed ID: 26658685

Title: A de novo mutation in KCNN3 associated with autosomal dominant idiopathic non-cirrhotic portal hypertension.

PubMed ID: 26658685

DOI: 10.1016/j.jhep.2015.11.027

Sequence Information:

  • Length: 731
  • Mass: 81385
  • Checksum: 02E5E79D7EAAAC29
  • Sequence:
    • MDTSGHFHDS GVGDLDEDPK CPCPSSGDEQ QQQQQQQQQQ QPPPPAPPAA PQQPLGPSLQ 
PQPPQLQQQQ QQQQQQQQQQ PPHPLSQLAQ LQSQPVHPGL LHSSPTAFRA PPSSNSTAIL 
HPSSRQGSQL NLNDHLLGHS PSSTATSGPG GGSRHRQASP LVHRRDSNPF TEIAMSSCKY 
SGGVMKPLSR LSASRRNLIE AETEGQPLQL FSPSNPPEIV ISSREDNHAH QTLLHHPNAT 
HNHQHAGTTA SSTTFPKANK RKNQNIGYKL GHRRALFEKR KRLSDYALIF GMFGIVVMVI 
ETELSWGLYS KDSMFSLALK CLISLSTIIL LGLIIAYHTR EVQLFVIDNG ADDWRIAMTY 
ERILYISLEM LVCAIHPIPG EYKFFWTARL AFSYTPSRAE ADVDIILSIP MFLRLYLIAR 
VMLLHSKLFT DASSRSIGAL NKINFNTRFV MKTLMTICPG TVLLVFSISL WIIAAWTVRV 
CERYHDQQDV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA 
VVARKLELTK AEKHVHNFMM DTQLTKRIKN AAANVLRETW LIYKHTKLLK KIDHAKVRKH 
QRKFLQAIHQ LRSVKMEQRK LSDQANTLVD LSKMQNVMYD LITELNDRSE DLEKQIGSLE 
SKLEHLTASF NSLPLLIADT LRQQQQQLLS AIIEARGVSV AVGTTHTPIS DSPIGVSSTS 
FPTPYTSSSS C

Genular Protein ID: 3670895700

Symbol: A0A087WYJ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WYJ0

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 746
  • Mass: 82809
  • Checksum: DBAEBC1D1762C237
  • Sequence:
    • MDTSGHFHDS GVGDLDEDPK CPCPSSGDEQ QQQQQQQQQQ QPPPPAPPAA PQQPLGPSLQ 
PQPPQLQQQQ QQQQQQQQQQ PPHPLSQLAQ LQSQPVHPGL LHSSPTAFRA PPSSNSTAIL 
HPSSRQGSQL NLNDHLLGHS PSSTATSGPG GGSRHRQASP LVHRRDSNPF TEIAMSSCKY 
SGGVMKPLSR LSASRRNLIE AETEGQPLQL FSPSNPPEIV ISSREDNHAH QTLLHHPNAT 
HNHQHAGTTA SSTTFPKANK RKNQNIGYKL GHRRALFEKR KRLSDYALIF GMFGIVVMVI 
ETELSWGLYS KDSMFSLALK CLISLSTIIL LGLIIAYHTR EVQLFVIDNG ADDWRIAMTY 
ERILYISLEM LVCAIHPIPG EYKFFWTARL AFSYTPSRAE ADVDIILSIP MFLRLYLIAR 
VMLLHSKLFT DASSRSIGAL NKINFNTRFV MKTLMTICPG TVLLVFSISL WIIAAWTVRV 
CESPESPAQP SGSSLPAWYH DQQDVTSNFL GAMWLISITF LSIGYGDMVP HTYCGKGVCL 
LTGIMGAGCT ALVVAVVARK LELTKAEKHV HNFMMDTQLT KRIKNAAANV LRETWLIYKH 
TKLLKKIDHA KVRKHQRKFL QAIHQLRSVK MEQRKLSDQA NTLVDLSKMQ NVMYDLITEL 
NDRSEDLEKQ IGSLESKLEH LTASFNSLPL LIADTLRQQQ QQLLSAIIEA RGVSVAVGTT 
HTPISDSPIG VSSTSFPTPY TSSSSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.