Details for: LAMC1

Gene ID: 3915

Symbol: LAMC1

Ensembl ID: ENSG00000135862

Description: laminin subunit gamma 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 333.4400
    Cell Significance Index: -51.8700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 204.0660
    Cell Significance Index: -51.7600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 124.0206
    Cell Significance Index: -51.0900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 110.5645
    Cell Significance Index: -52.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 110.3981
    Cell Significance Index: -44.8500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 46.9550
    Cell Significance Index: -44.8300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.0494
    Cell Significance Index: -51.8500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 23.8712
    Cell Significance Index: 161.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 22.8047
    Cell Significance Index: -49.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.1600
    Cell Significance Index: -51.9300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 6.5476
    Cell Significance Index: 127.7900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.7907
    Cell Significance Index: 127.9200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 4.6044
    Cell Significance Index: 66.1200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.8143
    Cell Significance Index: 72.3400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.5242
    Cell Significance Index: 500.9400
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 1.8241
    Cell Significance Index: 22.9700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.7110
    Cell Significance Index: 934.4100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6283
    Cell Significance Index: 326.6300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2079
    Cell Significance Index: 92.7000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0808
    Cell Significance Index: 15.5500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0251
    Cell Significance Index: 195.0900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.0239
    Cell Significance Index: 51.7500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.9101
    Cell Significance Index: 26.0900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7597
    Cell Significance Index: 93.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7256
    Cell Significance Index: 99.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6547
    Cell Significance Index: 28.9600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.6501
    Cell Significance Index: 13.9000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5613
    Cell Significance Index: 201.3300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5525
    Cell Significance Index: 382.1200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5457
    Cell Significance Index: 15.2500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5190
    Cell Significance Index: 19.6600
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.5169
    Cell Significance Index: 2.2500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4984
    Cell Significance Index: 450.0300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4876
    Cell Significance Index: 32.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.4855
    Cell Significance Index: 220.3600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.4287
    Cell Significance Index: 2.5900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4221
    Cell Significance Index: 76.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3487
    Cell Significance Index: 9.4900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.2369
    Cell Significance Index: 5.7800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2291
    Cell Significance Index: 145.4900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1847
    Cell Significance Index: 347.6800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1840
    Cell Significance Index: 29.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1497
    Cell Significance Index: 2.2100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0994
    Cell Significance Index: 43.9600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0535
    Cell Significance Index: 6.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0525
    Cell Significance Index: 80.8300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0321
    Cell Significance Index: 3.4900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0318
    Cell Significance Index: 3.1500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0308
    Cell Significance Index: 1.7300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0122
    Cell Significance Index: 22.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0067
    Cell Significance Index: 1.1400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0063
    Cell Significance Index: 0.1100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.0022
    Cell Significance Index: 0.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0013
    Cell Significance Index: 1.8200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0009
    Cell Significance Index: -0.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0104
    Cell Significance Index: -0.3000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0153
    Cell Significance Index: -9.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0234
    Cell Significance Index: -17.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0317
    Cell Significance Index: -0.8300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0485
    Cell Significance Index: -27.3500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0531
    Cell Significance Index: -0.9100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0540
    Cell Significance Index: -40.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0571
    Cell Significance Index: -41.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1269
    Cell Significance Index: -18.4500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1371
    Cell Significance Index: -15.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1506
    Cell Significance Index: -43.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1506
    Cell Significance Index: -17.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1529
    Cell Significance Index: -6.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1601
    Cell Significance Index: -33.7300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1922
    Cell Significance Index: -24.8300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1935
    Cell Significance Index: -20.1500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2506
    Cell Significance Index: -5.4300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.2567
    Cell Significance Index: -17.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2585
    Cell Significance Index: -12.1500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2834
    Cell Significance Index: -28.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3488
    Cell Significance Index: -18.1700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3869
    Cell Significance Index: -23.7800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4091
    Cell Significance Index: -28.9300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4184
    Cell Significance Index: -25.6500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4221
    Cell Significance Index: -48.1900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4295
    Cell Significance Index: -22.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4586
    Cell Significance Index: -54.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4756
    Cell Significance Index: -22.1800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.5004
    Cell Significance Index: -11.5600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5072
    Cell Significance Index: -37.8000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5129
    Cell Significance Index: -10.6400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5200
    Cell Significance Index: -14.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5347
    Cell Significance Index: -18.5800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5605
    Cell Significance Index: -15.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6296
    Cell Significance Index: -8.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6348
    Cell Significance Index: -50.2800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.6519
    Cell Significance Index: -3.0100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7676
    Cell Significance Index: -49.5200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.8957
    Cell Significance Index: -56.4500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9069
    Cell Significance Index: -19.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.9403
    Cell Significance Index: -49.3700
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.9688
    Cell Significance Index: -8.6000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.9870
    Cell Significance Index: -12.6400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9887
    Cell Significance Index: -32.3700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9911
    Cell Significance Index: -31.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** LAMC1 is a type of laminin subunit, specifically gamma-1, which is one of the three subunits that make up laminin-1, a major component of the basal lamina. Laminin-1 is a heterotrimeric protein consisting of alpha, beta, and gamma chains. The gamma-1 chain is the most abundant subunit of laminin-1 and is essential for its function. LAMC1 is a transmembrane protein, with a short cytoplasmic tail and a long extracellular domain that interacts with other ECM proteins and cell surface receptors. The protein has a unique structure, with a globular head domain and a fibrous tail domain, which allows it to interact with a wide range of ligands, including integrins, collagens, and proteoglycans. **Pathways and Functions** LAMC1 plays a crucial role in various biological processes, including: 1. **Cell adhesion**: LAMC1 interacts with integrins and other ECM proteins to mediate cell adhesion to the ECM, which is essential for tissue development and maintenance. 2. **Cell migration**: LAMC1 is involved in cell migration, particularly during embryonic development and tissue repair. 3. **Differentiation**: LAMC1 regulates cell differentiation, particularly in skeletal muscle and cardiac muscle cells. 4. **Signaling**: LAMC1 interacts with various signaling molecules, including growth factors and cytokines, to regulate cell behavior. 5. **ECM organization**: LAMC1 is involved in the organization of the ECM, particularly in the formation of the basal lamina. **Clinical Significance** LAMC1 is significantly expressed in various diseases, including: 1. **Muscular dystrophy**: Mutations in LAMC1 have been associated with muscular dystrophy, particularly in skeletal muscle. 2. **Cancer**: LAMC1 is overexpressed in various types of cancer, including breast, lung, and colon cancer. 3. **Neurological disorders**: LAMC1 is involved in the pathogenesis of neurological disorders, including Alzheimer's disease and multiple sclerosis. 4. **Cardiovascular disease**: LAMC1 is involved in the development of cardiovascular disease, particularly in atherosclerosis and cardiac hypertrophy. In conclusion, LAMC1 is a crucial component of the ECM that plays a significant role in various biological processes, including cell adhesion, migration, and differentiation. Its dysregulation is associated with various diseases, including muscular dystrophy, cancer, neurological disorders, and cardiovascular disease. Further research is needed to fully understand the functions and clinical significance of LAMC1.

Genular Protein ID: 2823062116

Symbol: LAMC1_HUMAN

Name: Laminin subunit gamma-1

UniProtKB Accession Codes:

P11047 Q5VYE7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 CarbonylDB 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 11 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 31 EMDB 2 Ensembl 1 ExpressionAtlas 1 GO 24 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3360804

Title: Human laminin B2 chain. Comparison of the complete amino acid sequence with the B1 chain reveals variability in sequence homology between different structural domains.

PubMed ID: 3360804

DOI: 10.1016/s0021-9258(18)68707-1

PubMed ID: 1985895

Title: Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain gene.

PubMed ID: 1985895

DOI: 10.1016/s0021-9258(18)52424-8

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 1806043

Title: Differences in human laminin B2 sequences.

PubMed ID: 1806043

DOI: 10.3109/10425179109020782

PubMed ID: 3234037

Title: Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25-->q31.

PubMed ID: 3234037

DOI: 10.1159/000132610

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

Sequence Information:

  • Length: 1609
  • Mass: 177603
  • Checksum: 42D9A9958EEBBB01
  • Sequence:
    • MRGSHRAAPA LRPRGRLWPV LAVLAAAAAA GCAQAAMDEC TDEGGRPQRC MPEFVNAAFN 
VTVVATNTCG TPPEEYCVQT GVTGVTKSCH LCDAGQPHLQ HGAAFLTDYN NQADTTWWQS 
QTMLAGVQYP SSINLTLHLG KAFDITYVRL KFHTSRPESF AIYKRTREDG PWIPYQYYSG 
SCENTYSKAN RGFIRTGGDE QQALCTDEFS DISPLTGGNV AFSTLEGRPS AYNFDNSPVL 
QEWVTATDIR VTLNRLNTFG DEVFNDPKVL KSYYYAISDF AVGGRCKCNG HASECMKNEF 
DKLVCNCKHN TYGVDCEKCL PFFNDRPWRR ATAESASECL PCDCNGRSQE CYFDPELYRS 
TGHGGHCTNC QDNTDGAHCE RCRENFFRLG NNEACSSCHC SPVGSLSTQC DSYGRCSCKP 
GVMGDKCDRC QPGFHSLTEA GCRPCSCDPS GSIDECNIET GRCVCKDNVE GFNCERCKPG 
FFNLESSNPR GCTPCFCFGH SSVCTNAVGY SVYSISSTFQ IDEDGWRAEQ RDGSEASLEW 
SSERQDIAVI SDSYFPRYFI APAKFLGKQV LSYGQNLSFS FRVDRRDTRL SAEDLVLEGA 
GLRVSVPLIA QGNSYPSETT VKYVFRLHEA TDYPWRPALT PFEFQKLLNN LTSIKIRGTY 
SERSAGYLDD VTLASARPGP GVPATWVESC TCPVGYGGQF CEMCLSGYRR ETPNLGPYSP 
CVLCACNGHS ETCDPETGVC NCRDNTAGPH CEKCSDGYYG DSTAGTSSDC QPCPCPGGSS 
CAVVPKTKEV VCTNCPTGTT GKRCELCDDG YFGDPLGRNG PVRLCRLCQC SDNIDPNAVG 
NCNRLTGECL KCIYNTAGFY CDRCKDGFFG NPLAPNPADK CKACNCNLYG TMKQQSSCNP 
VTGQCECLPH VTGQDCGACD PGFYNLQSGQ GCERCDCHAL GSTNGQCDIR TGQCECQPGI 
TGQHCERCEV NHFGFGPEGC KPCDCHPEGS LSLQCKDDGR CECREGFVGN RCDQCEENYF 
YNRSWPGCQE CPACYRLVKD KVADHRVKLQ ELESLIANLG TGDEMVTDQA FEDRLKEAER 
EVMDLLREAQ DVKDVDQNLM DRLQRVNNTL SSQISRLQNI RNTIEETGNL AEQARAHVEN 
TERLIEIASR ELEKAKVAAA NVSVTQPEST GDPNNMTLLA EEARKLAERH KQEADDIVRV 
AKTANDTSTE AYNLLLRTLA GENQTAFEIE ELNRKYEQAK NISQDLEKQA ARVHEEAKRA 
GDKAVEIYAS VAQLSPLDSE TLENEANNIK MEAENLEQLI DQKLKDYEDL REDMRGKELE 
VKNLLEKGKT EQQTADQLLA RADAAKALAE EAAKKGRDTL QEANDILNNL KDFDRRVNDN 
KTAAEEALRK IPAINQTITE ANEKTREAQQ ALGSAAADAT EAKNKAHEAE RIASAVQKNA 
TSTKAEAERT FAEVTDLDNE VNNMLKQLQE AEKELKRKQD DADQDMMMAG MASQAAQEAE 
INARKAKNSV TSLLSIINDL LEQLGQLDTV DLNKLNEIEG TLNKAKDEMK VSDLDRKVSD 
LENEAKKQEA AIMDYNRDIE EIMKDIRNLE DIRKTLPSGC FNTPSIEKP

Genular Protein ID: 3130512742

Symbol: Q6NVY8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NVY8

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SMR 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 248
  • Mass: 27079
  • Checksum: E42903FF0505C03D
  • Sequence:
    • MRGSHRAAPA LRPRGRLWPV LAVLAAAAAA GCAQAAMDEC TDEGGRPQRC MPEFVNAAFN 
VTVVATNTCG TPPEEYCVQT GVTGVTKSCH LCDAGQPHLQ HGAAFLTDYN NQADTTWWQS 
QTMLAGVQYP SSINLTLHLG KAFDITYVRL KFHTSRPESF AIYKRTREDG PWIPYQYYSG 
SCENTYSKAN RGFIRTGGDE QQALCTDEFS DISPLTGGNV AFSTLEGRPS AYNFDNSPVL 
QVNSHRLA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.