Details for: LGALS1

Gene ID: 3956

Symbol: LGALS1

Ensembl ID: ENSG00000100097

Description: galectin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 640.4568
    Cell Significance Index: -99.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 375.4484
    Cell Significance Index: -95.2300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 253.8308
    Cell Significance Index: -104.5700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 215.2619
    Cell Significance Index: -101.6300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 210.0566
    Cell Significance Index: -108.0500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 79.3459
    Cell Significance Index: -97.8300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 30.3620
    Cell Significance Index: -66.4500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 29.6863
    Cell Significance Index: -91.1800
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 27.4750
    Cell Significance Index: 114.3500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 26.1097
    Cell Significance Index: -103.0300
  • Cell Name: theca cell (CL0000503)
    Fold Change: 25.7327
    Cell Significance Index: 151.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.0031
    Cell Significance Index: -42.8700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 15.5334
    Cell Significance Index: 325.1400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 14.8376
    Cell Significance Index: 190.0200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 14.1089
    Cell Significance Index: 260.7700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 11.8019
    Cell Significance Index: 346.6100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 10.0488
    Cell Significance Index: 288.0600
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 8.9101
    Cell Significance Index: 41.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 7.8960
    Cell Significance Index: 1012.2200
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 7.8587
    Cell Significance Index: 67.5300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 7.6560
    Cell Significance Index: 1051.3900
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 7.2596
    Cell Significance Index: 38.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 7.0401
    Cell Significance Index: 454.1900
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 6.2529
    Cell Significance Index: 38.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 4.2334
    Cell Significance Index: 493.3500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 3.3062
    Cell Significance Index: 58.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.5528
    Cell Significance Index: 119.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.9458
    Cell Significance Index: 860.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.6316
    Cell Significance Index: 469.4600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 1.1288
    Cell Significance Index: 6.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0550
    Cell Significance Index: 576.1400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0507
    Cell Significance Index: 199.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0163
    Cell Significance Index: 53.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8471
    Cell Significance Index: 59.9100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.8208
    Cell Significance Index: 16.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7065
    Cell Significance Index: 19.2300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6714
    Cell Significance Index: 606.2400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6559
    Cell Significance Index: 7.1300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.5713
    Cell Significance Index: 3.5500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5396
    Cell Significance Index: 69.7100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4512
    Cell Significance Index: 12.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.3624
    Cell Significance Index: 6.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3006
    Cell Significance Index: 54.2000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2576
    Cell Significance Index: 19.2000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2242
    Cell Significance Index: 10.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0417
    Cell Significance Index: 4.2600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0380
    Cell Significance Index: 1.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0233
    Cell Significance Index: 2.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0051
    Cell Significance Index: -0.8400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0062
    Cell Significance Index: -0.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0064
    Cell Significance Index: -4.8600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0281
    Cell Significance Index: -2.7800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0296
    Cell Significance Index: -55.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0326
    Cell Significance Index: -60.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0346
    Cell Significance Index: -47.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0396
    Cell Significance Index: -60.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0610
    Cell Significance Index: -45.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1215
    Cell Significance Index: -75.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1388
    Cell Significance Index: -101.7600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1439
    Cell Significance Index: -91.4200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1469
    Cell Significance Index: -82.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1784
    Cell Significance Index: -80.9700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1905
    Cell Significance Index: -1.6000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.2456
    Cell Significance Index: -49.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2507
    Cell Significance Index: -42.8100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2606
    Cell Significance Index: -51.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.2610
    Cell Significance Index: -93.6000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2704
    Cell Significance Index: -9.5000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3219
    Cell Significance Index: -4.9800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3264
    Cell Significance Index: -8.7100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3427
    Cell Significance Index: -40.4200
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -0.3731
    Cell Significance Index: -2.1900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4151
    Cell Significance Index: -87.4300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.4535
    Cell Significance Index: -49.3300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.6118
    Cell Significance Index: -27.7300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.6270
    Cell Significance Index: -91.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6340
    Cell Significance Index: -72.6300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.7167
    Cell Significance Index: -20.6500
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.8493
    Cell Significance Index: -14.5900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8523
    Cell Significance Index: -97.2900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.8563
    Cell Significance Index: -8.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8607
    Cell Significance Index: -66.0500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.9591
    Cell Significance Index: -66.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9711
    Cell Significance Index: -101.1100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.0643
    Cell Significance Index: -27.1900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.1172
    Cell Significance Index: -68.6700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2130
    Cell Significance Index: -74.3700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3158
    Cell Significance Index: -45.7300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.3163
    Cell Significance Index: -104.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.3754
    Cell Significance Index: -82.5700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4381
    Cell Significance Index: -46.0600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.4818
    Cell Significance Index: -37.0400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.5185
    Cell Significance Index: -78.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.6518
    Cell Significance Index: -111.0700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.6587
    Cell Significance Index: -104.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.9964
    Cell Significance Index: -112.0300
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -2.0668
    Cell Significance Index: -35.6300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -2.1562
    Cell Significance Index: -52.6100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -2.2049
    Cell Significance Index: -17.9800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -2.4286
    Cell Significance Index: -56.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Carbohydrate-binding protein**: Galectin 1 binds to specific carbohydrate motifs, influencing cell-cell interactions, adhesion, and signaling. 2. **Immune response modulation**: Galectin 1 regulates immune cell function, including dendritic cell differentiation, T-cell costimulation, and the modulation of inflammatory responses. 3. **Apoptosis regulation**: Galectin 1 modulates apoptosis, influencing the survival and death of cells in response to stress and injury. 4. **Cell differentiation**: Galectin 1 is involved in the regulation of cell differentiation, particularly in the development of immune cells and myoblasts. 5. **Extracellular matrix dynamics**: Galectin 1 interacts with extracellular matrix components, influencing cell adhesion, migration, and tissue remodeling. **Pathways and Functions:** 1. **Apoptotic process**: Galectin 1 modulates apoptosis by interacting with specific cellular proteins, influencing the activation of caspases and the release of cytochrome c. 2. **Cell-cell adhesion**: Galectin 1 binds to carbohydrate motifs on cell surfaces, facilitating cell-cell interactions and adhesion. 3. **Collagen-containing extracellular matrix**: Galectin 1 interacts with collagen and other extracellular matrix components, influencing cell adhesion, migration, and tissue remodeling. 4. **Post-translational protein modification**: Galectin 1 participates in post-translational protein modifications, including protein phosphorylation and dephosphorylation. 5. **Inflammatory response**: Galectin 1 modulates the inflammatory response by regulating the expression of pro-inflammatory cytokines and chemokines. **Clinical Significance:** 1. **Cancer**: Galectin 1 has been implicated in the progression and metastasis of various cancers, including breast, lung, and colon cancer. 2. **Autoimmune diseases**: Galectin 1 may play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus. 3. **Infectious diseases**: Galectin 1 has been shown to regulate the entry of viruses into host cells, highlighting its potential role in viral infections. 4. **Immune-related disorders**: Galectin 1 may be involved in the regulation of immune cell function in disorders such as immunodeficiency and autoimmune diseases. 5. **Regenerative medicine**: Galectin 1 has been investigated as a potential therapeutic target for tissue engineering and regenerative medicine applications. In conclusion, galectin 1 is a multifaceted protein that plays a crucial role in various biological processes, including immune response modulation, cell differentiation, and extracellular matrix dynamics. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the molecular mechanisms underlying its functions and potential therapeutic applications.

Genular Protein ID: 2330560813

Symbol: LEG1_HUMAN

Name: Galectin-1

UniProtKB Accession Codes:

P09382 B2R5E8 Q9UDK5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 7 CPTC 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 13 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 2 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 38 PDBsum 38 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2719964

Title: Cloning and nucleotide sequence of a full-length cDNA for human 14 kDa beta-galactoside-binding lectin.

PubMed ID: 2719964

DOI: 10.1016/0167-4781(89)90173-5

PubMed ID: 2910856

Title: Molecular cloning, characterization, and expression of a human 14-kDa lectin.

PubMed ID: 2910856

DOI: 10.1016/s0021-9258(19)85087-1

PubMed ID: 2719646

Title: Evidence that the 14 kDa soluble beta-galactoside-binding lectin in man is encoded by a single gene.

PubMed ID: 2719646

DOI: 10.1042/bj2590291

PubMed ID: 18824694

Title: Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance.

PubMed ID: 18824694

DOI: 10.1073/pnas.0807606105

PubMed ID: 1988031

Title: Genomic sequence and organization of two members of a human lectin gene family.

PubMed ID: 1988031

DOI: 10.1021/bi00215a013

PubMed ID: 12761501

Title: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

PubMed ID: 12761501

DOI: 10.1038/sj.onc.1206406

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3065332

Title: Complete amino acid sequence of a beta-galactoside-binding lectin from human placenta.

PubMed ID: 3065332

DOI: 10.1093/oxfordjournals.jbchem.a122401

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 3611046

Title: Further characterization and structural studies on human placenta lectin.

PubMed ID: 3611046

DOI: 10.1093/oxfordjournals.jbchem.a121968

PubMed ID: 1386213

Title: Identification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin.

PubMed ID: 1386213

DOI: 10.1016/0003-9861(92)90650-l

PubMed ID: 2383549

Title: Human splenic galaptin: physicochemical characterization.

PubMed ID: 2383549

DOI: 10.1021/bi00474a014

PubMed ID: 7501023

Title: Apoptosis of T cells mediated by galectin-1.

PubMed ID: 7501023

DOI: 10.1038/378736a0

PubMed ID: 10369126

Title: Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45.

PubMed ID: 10369126

DOI: 10.1016/s0165-2478(99)00012-7

PubMed ID: 10764829

Title: Regulation of CD45-induced signaling by galectin-1 in Burkitt lymphoma B cells.

PubMed ID: 10764829

DOI: 10.1093/glycob/10.4.413

PubMed ID: 11146440

Title: Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation.

PubMed ID: 11146440

DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1022>3.3.co;2-q

PubMed ID: 14617626

Title: Presentation of galectin-1 by extracellular matrix triggers T cell death.

PubMed ID: 14617626

DOI: 10.1074/jbc.m311183200

PubMed ID: 19497882

Title: A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.

PubMed ID: 19497882

DOI: 10.1073/pnas.0903568106

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23131994

Title: Multiple functions of sushi domain containing 2 (SUSD2) in breast tumorigenesis.

PubMed ID: 23131994

DOI: 10.1158/1541-7786.mcr-12-0501-t

PubMed ID: 24945728

Title: Modulation of CD6 function through interaction with galectin-1 and -3.

PubMed ID: 24945728

DOI: 10.1016/j.febslet.2014.05.064

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24752896

Title: The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with galectin-1.

PubMed ID: 24752896

DOI: 10.1128/mcb.00348-14

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 32272059

Title: A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.

PubMed ID: 32272059

DOI: 10.1016/j.cell.2020.03.031

PubMed ID: 15476813

Title: Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding.

PubMed ID: 15476813

DOI: 10.1016/j.jmb.2004.08.078

PubMed ID: 18796645

Title: Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1.

PubMed ID: 18796645

DOI: 10.1093/glycob/cwn089

PubMed ID: 19128029

Title: Critical role of the solvent environment in galectin-1 binding to the disaccharide lactose.

PubMed ID: 19128029

DOI: 10.1021/bi801855g

Sequence Information:

  • Length: 135
  • Mass: 14716
  • Checksum: 2FBB8D7A1FC0F1F9
  • Sequence:
    • MACGLVASNL NLKPGECLRV RGEVAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV 
CNSKDGGAWG TEQREAVFPF QPGSVAEVCI TFDQANLTVK LPDGYEFKFP NRLNLEAINY 
MAADGDFKIK CVAFD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.