Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: gut endothelial cell (CL0000131)
Fold Change: 2.26
Marker Score: 810.5 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.98
Marker Score: 3357 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.93
Marker Score: 1811 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.77
Marker Score: 4804 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.63
Marker Score: 1741.5 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.61
Marker Score: 4772 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.48
Marker Score: 1488 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.39
Marker Score: 3785 - Cell Name: pro-T cell (CL0000827)
Fold Change: 1.2
Marker Score: 4927 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.2
Marker Score: 813 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.19
Marker Score: 896 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.13
Marker Score: 1360 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.11
Marker Score: 1575.5 - Cell Name: Unknown (CL0000548)
Fold Change: 1.07
Marker Score: 779 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.06
Marker Score: 2504 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.06
Marker Score: 2012 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.04
Marker Score: 330 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251706 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.04
Marker Score: 651 - Cell Name: neural cell (CL0002319)
Fold Change: 1.03
Marker Score: 497 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1
Marker Score: 600 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71724 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47949 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.99
Marker Score: 489 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30395 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.95
Marker Score: 2618 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2399 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.94
Marker Score: 304 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.94
Marker Score: 236 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 482 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.93
Marker Score: 636 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 436 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.92
Marker Score: 292 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5249 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.92
Marker Score: 515 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2707 - Cell Name: IgG plasmablast (CL0000982)
Fold Change: 0.88
Marker Score: 244 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.88
Marker Score: 1106 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.88
Marker Score: 13709 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5294 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308.5 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.85
Marker Score: 47548 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.83
Marker Score: 1105 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.83
Marker Score: 7100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.81
Marker Score: 8255 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.81
Marker Score: 445 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.8
Marker Score: 836 - Cell Name: stem cell (CL0000034)
Fold Change: 0.79
Marker Score: 1880.5 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.79
Marker Score: 455 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.79
Marker Score: 1969.5 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.79
Marker Score: 29852 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.79
Marker Score: 246 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 314 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1265 - Cell Name: centroblast (CL0009112)
Fold Change: 0.77
Marker Score: 379 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 587 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.76
Marker Score: 46800 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.75
Marker Score: 766 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.75
Marker Score: 2955 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.74
Marker Score: 4763 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.74
Marker Score: 364 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.74
Marker Score: 1740 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.74
Marker Score: 9733 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.73
Marker Score: 5594 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 375 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.72
Marker Score: 324 - Cell Name: blood cell (CL0000081)
Fold Change: 0.72
Marker Score: 8362 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.72
Marker Score: 6831 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.71
Marker Score: 1475 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.7
Marker Score: 291 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.7
Marker Score: 229 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.69
Marker Score: 243 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.69
Marker Score: 222 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.69
Marker Score: 438 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.69
Marker Score: 6830 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.69
Marker Score: 164 - Cell Name: brush cell (CL0002204)
Fold Change: 0.68
Marker Score: 622 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.68
Marker Score: 482 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.67
Marker Score: 2831 - Cell Name: neuron (CL0000540)
Fold Change: 0.67
Marker Score: 2744 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.67
Marker Score: 2575 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.66
Marker Score: 621 - Cell Name: glial cell (CL0000125)
Fold Change: 0.65
Marker Score: 720 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.65
Marker Score: 173 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.65
Marker Score: 9718 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.64
Marker Score: 402 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.64
Marker Score: 719 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.64
Marker Score: 439 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.64
Marker Score: 338 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.63
Marker Score: 386 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.63
Marker Score: 405 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.63
Marker Score: 189 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.62
Marker Score: 286 - Cell Name: Unknown (CL0002371)
Fold Change: 0.61
Marker Score: 648 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.61
Marker Score: 404 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.61
Marker Score: 486 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 0.6
Marker Score: 1765 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.6
Marker Score: 442 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.6
Marker Score: 11902
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Other Information
Genular Protein ID: 3779653985
Symbol: LMNB1_HUMAN
Name: Lamin-B1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2325650
Title: In vitro posttranslational modification of lamin B cloned from a human T-cell line.
PubMed ID: 2325650
PubMed ID: 7557986
Title: Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.
PubMed ID: 7557986
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2684976
Title: Human lamin B contains a farnesylated cysteine residue.
PubMed ID: 2684976
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 16951681
Title: Lamin B1 duplications cause autosomal dominant leukodystrophy.
PubMed ID: 16951681
DOI: 10.1038/ng1872
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25775403
Title: SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells.
PubMed ID: 25775403
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 22265972
Title: Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
PubMed ID: 22265972
PubMed ID: 24686783
Title: Mutations in the matrin 3 gene cause familial amyotrophic lateral sclerosis.
PubMed ID: 24686783
DOI: 10.1038/nn.3688
PubMed ID: 28716252
Title: LMNB1 mutation causes cerebellar involvement and a genome instability defect.
PubMed ID: 28716252
PubMed ID: 32910914
Title: De Novo Variants in LMNB1 Cause Pronounced Syndromic Microcephaly and Disruption of Nuclear Envelope Integrity.
PubMed ID: 32910914
PubMed ID: 33033404
Title: Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy.
PubMed ID: 33033404
Sequence Information:
- Length: 586
- Mass: 66408
- Checksum: 73292877745722C4
- Sequence:
MATATPVPPR MGSRAGGPTT PLSPTRLSRL QEKEELRELN DRLAVYIDKV RSLETENSAL QLQVTEREEV RGRELTGLKA LYETELADAR RALDDTARER AKLQIELGKC KAEHDQLLLN YAKKESDLNG AQIKLREYEA ALNSKDAALA TALGDKKSLE GDLEDLKDQI AQLEASLAAA KKQLADETLL KVDLENRCQS LTEDLEFRKS MYEEEINETR RKHETRLVEV DSGRQIEYEY KLAQALHEMR EQHDAQVRLY KEELEQTYHA KLENARLSSE MNTSTVNSAR EELMESRMRI ESLSSQLSNL QKESRACLER IQELEDLLAK EKDNSRRMLT DKEREMAEIR DQMQQQLNDY EQLLDVKLAL DMEISAYRKL LEGEEERLKL SPSPSSRVTV SRASSSRSVR TTRGKRKRVD VEESEASSSV SISHSASATG NVCIEEIDVD GKFIRLKNTS EQDQPMGGWE MIRKIGDTSV SYKYTSRYVL KAGQTVTIWA ANAGVTASPP TDLIWKNQNS WGTGEDVKVI LKNSQGEEVA QRSTVFKTTI PEEEEEEEEA AGVVVEEELF HQQGTPRASN RSCAIM
Genular Protein ID: 2269307674
Symbol: B4DZT3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 376
- Mass: 43034
- Checksum: 7AE8F395AF286EB9
- Sequence:
MYEEEINETR RKHETRLVEV DPGRQIEYEY KLAQALHEMR EQHDAQVRLY KEELEQTYHA KLENARLSSE MNTSTVNSAR EELMESRMRI ESLSSQLSNL QKESRACLER IQELEDLLAK EKDNSRRMLT DKEREMAEIR DQMQQQLNDY EQLLDVKLAL DMEISAYRKL LEGEEERLKL SPSPSSRVTV SRASSSRSVR TTRGKRKRVD VEESEASSSV SISHSASATG NVCIEEIDVD GKFIRLKNTS EQDQPMGGWE MIRKIGDTSV SYKYTSRYVL KAGQTVTIWA ANAGVTASPP TDLIWKNQNS WGTGEDVKVI LKNSQGEEVA QRSTVFKTTI PEEEEEEEEA AGVVVEEELF HQQGTPRASN RSCAIM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.