Details for: BCAM

Gene ID: 4059

Symbol: BCAM

Ensembl ID: ENSG00000187244

Description: basal cell adhesion molecule (Lutheran blood group)

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 160.1463
    Cell Significance Index: -24.9100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 115.5165
    Cell Significance Index: -29.3000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 71.6110
    Cell Significance Index: -29.5000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 65.0573
    Cell Significance Index: -26.4300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 60.1115
    Cell Significance Index: -28.3800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.3058
    Cell Significance Index: -26.0700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.0422
    Cell Significance Index: -28.4100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 17.0285
    Cell Significance Index: 135.9600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 13.6896
    Cell Significance Index: 114.9900
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 12.1794
    Cell Significance Index: 59.2400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 10.0556
    Cell Significance Index: 177.7000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.5873
    Cell Significance Index: -29.9400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.4934
    Cell Significance Index: -16.4000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 7.1277
    Cell Significance Index: 43.8700
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 6.8914
    Cell Significance Index: 31.8300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 4.0919
    Cell Significance Index: 213.1400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 4.0812
    Cell Significance Index: 304.1700
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 3.8731
    Cell Significance Index: 14.8300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.8414
    Cell Significance Index: 104.5600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.9347
    Cell Significance Index: 33.3400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.6708
    Cell Significance Index: 1458.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.1746
    Cell Significance Index: 431.5600
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 2.1194
    Cell Significance Index: 12.7000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.8798
    Cell Significance Index: 25.6500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.6816
    Cell Significance Index: 38.8500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.5627
    Cell Significance Index: 182.1200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.4556
    Cell Significance Index: 50.5800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.4065
    Cell Significance Index: 621.8600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8326
    Cell Significance Index: 102.3700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.8041
    Cell Significance Index: 12.4400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7408
    Cell Significance Index: 120.4800
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.6301
    Cell Significance Index: 5.4500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6057
    Cell Significance Index: 65.8800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5852
    Cell Significance Index: 15.6300
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.5550
    Cell Significance Index: 3.4800
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.5167
    Cell Significance Index: 5.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4902
    Cell Significance Index: 34.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4847
    Cell Significance Index: 87.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4073
    Cell Significance Index: 18.9900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3568
    Cell Significance Index: 10.2800
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.3437
    Cell Significance Index: 1.1800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3148
    Cell Significance Index: 21.7700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3035
    Cell Significance Index: 39.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2350
    Cell Significance Index: 44.7300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2336
    Cell Significance Index: 10.5900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.2297
    Cell Significance Index: 168.4300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2146
    Cell Significance Index: 21.2300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1676
    Cell Significance Index: 3.6300
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.1343
    Cell Significance Index: 1.3900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1019
    Cell Significance Index: 187.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0943
    Cell Significance Index: 12.1000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0926
    Cell Significance Index: 5.5600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0586
    Cell Significance Index: 44.3800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0509
    Cell Significance Index: 1.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0380
    Cell Significance Index: 17.2500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0380
    Cell Significance Index: 1.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0369
    Cell Significance Index: 56.7500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0127
    Cell Significance Index: 1.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0070
    Cell Significance Index: -13.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0198
    Cell Significance Index: -14.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0202
    Cell Significance Index: -27.4300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0256
    Cell Significance Index: -16.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0262
    Cell Significance Index: -18.1000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0414
    Cell Significance Index: -14.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0422
    Cell Significance Index: -7.2100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0451
    Cell Significance Index: -25.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0537
    Cell Significance Index: -33.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0665
    Cell Significance Index: -6.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0741
    Cell Significance Index: -1.2400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0788
    Cell Significance Index: -22.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0877
    Cell Significance Index: -10.0500
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0933
    Cell Significance Index: -0.6700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0966
    Cell Significance Index: -2.7000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1028
    Cell Significance Index: -4.8300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1145
    Cell Significance Index: -1.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1186
    Cell Significance Index: -23.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1364
    Cell Significance Index: -28.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1584
    Cell Significance Index: -3.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1594
    Cell Significance Index: -23.1700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2093
    Cell Significance Index: -16.0600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2379
    Cell Significance Index: -12.0200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2424
    Cell Significance Index: -12.5900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2574
    Cell Significance Index: -3.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2673
    Cell Significance Index: -27.8300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2874
    Cell Significance Index: -22.7700
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.2951
    Cell Significance Index: -3.8000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2991
    Cell Significance Index: -3.8300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3392
    Cell Significance Index: -13.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3628
    Cell Significance Index: -20.3600
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.3854
    Cell Significance Index: -4.4800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3975
    Cell Significance Index: -8.4700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4260
    Cell Significance Index: -13.6500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4452
    Cell Significance Index: -28.7200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4484
    Cell Significance Index: -30.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4665
    Cell Significance Index: -29.4000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4694
    Cell Significance Index: -28.7800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4946
    Cell Significance Index: -30.4000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5674
    Cell Significance Index: -8.1600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5737
    Cell Significance Index: -11.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5833
    Cell Significance Index: -15.6300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** BCAM is a member of the immunoglobulin superfamily, characterized by its unique structure and expression patterns. It is primarily expressed on the surface of epithelial and endothelial cells, including those in the kidney, lung, and mammary gland. BCAM is known to interact with various ligands, including laminins, collagens, and other extracellular matrix molecules, facilitating cell adhesion and migration. Its expression is also regulated by various signaling pathways, including those involved in cell proliferation, differentiation, and survival. **Pathways and Functions:** BCAM is involved in several key signaling pathways, including: 1. **Cell-matrix adhesion:** BCAM interacts with laminins and collagens to mediate cell adhesion and migration, which is essential for tissue development, repair, and remodeling. 2. **Transmembrane signaling:** BCAM can act as a transmembrane receptor, transmitting signals that regulate cell proliferation, differentiation, and survival. 3. **Extracellular signaling:** BCAM can interact with extracellular ligands, such as laminins and collagens, to regulate signaling pathways involved in cell adhesion, migration, and differentiation. 4. **Immune response:** BCAM has been implicated in the regulation of immune responses, including the modulation of T-cell activation and the promotion of epithelial barrier function. **Clinical Significance:** BCAM has been implicated in various diseases, including: 1. **Kidney disease:** BCAM expression is altered in kidney diseases, such as diabetic nephropathy and glomerulonephritis, suggesting its role in kidney function and disease pathogenesis. 2. **Cancer:** BCAM expression is often upregulated in various types of cancer, including breast, lung, and colon cancer, suggesting its potential role in tumor progression and metastasis. 3. **Inflammatory diseases:** BCAM has been implicated in the regulation of inflammatory responses, including the promotion of epithelial barrier function and the modulation of T-cell activation. 4. **Neurological diseases:** BCAM expression is altered in neurological diseases, such as Alzheimer's disease and Parkinson's disease, suggesting its role in neurodegenerative processes. In conclusion, BCAM is a multifunctional protein that plays a critical role in cell adhesion, migration, and signaling. Its expression and function are regulated by various signaling pathways, and alterations in BCAM expression have been implicated in various diseases. Further research is needed to fully elucidate the role of BCAM in immune response and disease pathogenesis. **References:** * [Insert references to relevant studies and publications on BCAM] **Future Directions:** * Investigate the role of BCAM in specific disease models, such as cancer and kidney disease. * Elucidate the molecular mechanisms underlying BCAM-mediated cell adhesion and signaling. * Explore the therapeutic potential of BCAM-targeting strategies in various diseases. By continuing to study BCAM, we can gain a deeper understanding of its role in immune response and disease pathogenesis, ultimately leading to the development of novel therapeutic strategies.

Genular Protein ID: 3769318367

Symbol: BCAM_HUMAN

Name: Basal cell adhesion molecule

UniProtKB Accession Codes:

P50895 A8MYF9 A9YWT5 A9YWT6 Q86VC7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 8 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7777537

Title: The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver.

PubMed ID: 7777537

DOI: 10.1073/pnas.92.12.5496

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7954395

Title: Molecular cloning of the B-CAM cell surface glycoprotein of epithelial cancers: a novel member of the immunoglobulin superfamily.

PubMed ID: 7954395

PubMed ID: 9166867

Title: Use of domain-deletion mutants to locate Lutheran blood group antigens to each of the five immunoglobulin superfamily domains of the Lutheran glycoprotein: elucidation of the molecular basis of the Lu(a)/Lu(b) and the Au(a)/Au(b) polymorphisms.

PubMed ID: 9166867

PubMed ID: 9192786

Title: Organization of the human LU gene and molecular basis of the Lu(a)/Lu(b) blood group polymorphism.

PubMed ID: 9192786

PubMed ID: 9616226

Title: Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin.

PubMed ID: 9616226

DOI: 10.1172/jci1204

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 15975931

Title: Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.

PubMed ID: 15975931

DOI: 10.1074/jbc.m503293200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17319831

Title: Different inactivating mutations in the LU genes of three individuals with the Lutheran-null phenotype.

PubMed ID: 17319831

DOI: 10.1111/j.1537-2995.2006.01141.x

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17638854

Title: The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3.

PubMed ID: 17638854

DOI: 10.1182/blood-2007-06-094748

Sequence Information:

  • Length: 628
  • Mass: 67405
  • Checksum: C88F4F5C640C3F5B
  • Sequence:
    • MEPPDAPAQA RGAPRLLLLA VLLAAHPDAQ AEVRLSVPPL VEVMRGKSVI LDCTPTGTHD 
HYMLEWFLTD RSGARPRLAS AEMQGSELQV TMHDTRGRSP PYQLDSQGRL VLAEAQVGDE 
RDYVCVVRAG AAGTAEATAR LNVFAKPEAT EVSPNKGTLS VMEDSAQEIA TCNSRNGNPA 
PKITWYRNGQ RLEVPVEMNP EGYMTSRTVR EASGLLSLTS TLYLRLRKDD RDASFHCAAH 
YSLPEGRHGR LDSPTFHLTL HYPTEHVQFW VGSPSTPAGW VREGDTVQLL CRGDGSPSPE 
YTLFRLQDEQ EEVLNVNLEG NLTLEGVTRG QSGTYGCRVE DYDAADDVQL SKTLELRVAY 
LDPLELSEGK VLSLPLNSSA VVNCSVHGLP TPALRWTKDS TPLGDGPMLS LSSITFDSNG 
TYVCEASLPT VPVLSRTQNF TLLVQGSPEL KTAEIEPKAD GSWREGDEVT LICSARGHPD 
PKLSWSQLGG SPAEPIPGRQ GWVSSSLTLK VTSALSRDGI SCEASNPHGN KRHVFHFGTV 
SPQTSQAGVA VMAVAVSVGL LLLVVAVFYC VRRKGGPCCR QRREKGAPPP GEPGLSHSGS 
EQPEQTGLLM GGASGGARGG SGGFGDEC

Genular Protein ID: 4233784196

Symbol: A0A087WXM8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WXM8

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 588
  • Mass: 63694
  • Checksum: 5E61DACC360FB1FF
  • Sequence:
    • MEPPDAPAQA RGAPRLLLLA VLLAAHPDAQ AEVRLSVPPL VEVMRGKSVI LDCTPTGTHD 
HYMLEWFLTD RSGARPRLAS AEMQGSELQV TMHDTRGRSP PYQLDSQGRL VLAEAQVGDE 
RDYVCVVRAG AAGTAEATAR LNVFAKPEAT EVSPNKGTLS VMEDSAQEIA TCNSRNGNPA 
PKITWYRNGQ RLEVPVEMNP EGYMTSRTVR EASGLLSLTS TLYLRLRKDD RDASFHCAAH 
YSLPEGRHGR LDSPTFHLTL HYPTEHVQFW VGSPSTPAGW VREGDTVQLL CRGDGSPSPE 
YTLFRLQDEQ EEVLNVNLEG NLTLEGVTRG QSGTYGCRVE DYDAADDVQL SKTLELRVAY 
LDPLELSEGK VLSLPLNSSA VVNCSVHGLP TPALRWTKDS TPLGDGPMLS LSSITFDSNG 
TYVCEASLPT VPVLSRTQNF TLLVQGSPEL KTAEIEPKAD GSWREGDEVT LICSARGHPD 
PKLSWSQLGG SPAEPIPGRQ GWVSSSLTLK VTSALSRDGI SCEASNPHGN KRHVFHFGTV 
SPQTSQAGVA VMAVAVSVGL LLLVVAVFYC VRRKGGPCCR QRREKGAP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.