Details for: MDH1

Gene ID: 4190

Symbol: MDH1

Ensembl ID: ENSG00000014641

Description: malate dehydrogenase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 454.5302
    Cell Significance Index: -70.7000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 249.3659
    Cell Significance Index: -63.2500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 193.8839
    Cell Significance Index: -79.8700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 168.4308
    Cell Significance Index: -79.5200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 159.3695
    Cell Significance Index: -64.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 143.9194
    Cell Significance Index: -74.0300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 68.5944
    Cell Significance Index: -65.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 63.9926
    Cell Significance Index: -78.9000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.5750
    Cell Significance Index: -81.1900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.3119
    Cell Significance Index: -49.0600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.1966
    Cell Significance Index: -55.8900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.8230
    Cell Significance Index: -19.3100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 5.1733
    Cell Significance Index: 271.6200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.4331
    Cell Significance Index: 35.4000
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 4.0489
    Cell Significance Index: 34.0100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.5247
    Cell Significance Index: 410.6100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 2.3399
    Cell Significance Index: 34.5500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1099
    Cell Significance Index: 423.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.7868
    Cell Significance Index: 137.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.7739
    Cell Significance Index: 125.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.7001
    Cell Significance Index: 35.5900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6216
    Cell Significance Index: 191.2400
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.5678
    Cell Significance Index: 8.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.5067
    Cell Significance Index: 822.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.4776
    Cell Significance Index: 181.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.4535
    Cell Significance Index: 262.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4034
    Cell Significance Index: 192.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3612
    Cell Significance Index: 601.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.2289
    Cell Significance Index: 36.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.2089
    Cell Significance Index: 42.0100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.1869
    Cell Significance Index: 31.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.0443
    Cell Significance Index: 48.6900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.9684
    Cell Significance Index: 62.4800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.9681
    Cell Significance Index: 11.5400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9410
    Cell Significance Index: 44.2300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9287
    Cell Significance Index: 333.1300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9149
    Cell Significance Index: 117.2900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8472
    Cell Significance Index: 168.1300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.8160
    Cell Significance Index: 51.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7901
    Cell Significance Index: 102.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7704
    Cell Significance Index: 16.6900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7001
    Cell Significance Index: 133.2300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5864
    Cell Significance Index: 30.4600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5817
    Cell Significance Index: 13.4400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.5482
    Cell Significance Index: 5.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5041
    Cell Significance Index: 37.5700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3944
    Cell Significance Index: 10.7400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3398
    Cell Significance Index: 17.7000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.2595
    Cell Significance Index: 2.0000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2140
    Cell Significance Index: 148.0200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1795
    Cell Significance Index: 11.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1486
    Cell Significance Index: 108.9500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1301
    Cell Significance Index: 12.8700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0823
    Cell Significance Index: 154.9300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0605
    Cell Significance Index: 4.0700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0521
    Cell Significance Index: 1.3900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0512
    Cell Significance Index: 46.2300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0103
    Cell Significance Index: -0.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0151
    Cell Significance Index: -9.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0200
    Cell Significance Index: -9.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0230
    Cell Significance Index: -17.3900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0291
    Cell Significance Index: -53.7400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0367
    Cell Significance Index: -0.3900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0374
    Cell Significance Index: -57.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0468
    Cell Significance Index: -63.6700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0529
    Cell Significance Index: -1.8600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0552
    Cell Significance Index: -5.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0875
    Cell Significance Index: -64.8200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1040
    Cell Significance Index: -1.7400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1185
    Cell Significance Index: -2.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1238
    Cell Significance Index: -69.8400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1300
    Cell Significance Index: -5.7500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1459
    Cell Significance Index: -91.0800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1750
    Cell Significance Index: -4.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1758
    Cell Significance Index: -13.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2029
    Cell Significance Index: -23.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2118
    Cell Significance Index: -36.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2315
    Cell Significance Index: -66.6200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2892
    Cell Significance Index: -10.9500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2948
    Cell Significance Index: -2.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3014
    Cell Significance Index: -43.8200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3754
    Cell Significance Index: -9.5900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3841
    Cell Significance Index: -10.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3916
    Cell Significance Index: -44.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4206
    Cell Significance Index: -88.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6059
    Cell Significance Index: -34.0000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6459
    Cell Significance Index: -67.2500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6576
    Cell Significance Index: -17.6200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7299
    Cell Significance Index: -19.5300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7435
    Cell Significance Index: -18.1400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7809
    Cell Significance Index: -16.6300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.8172
    Cell Significance Index: -11.1500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.8254
    Cell Significance Index: -23.6600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.8564
    Cell Significance Index: -38.8200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.9733
    Cell Significance Index: -12.4700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.0783
    Cell Significance Index: -13.3800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.2495
    Cell Significance Index: -26.5200
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -1.2514
    Cell Significance Index: -17.5400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2669
    Cell Significance Index: -77.6700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2745
    Cell Significance Index: -31.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MDH1 is a member of the malate dehydrogenase family, which consists of enzymes that catalyze the oxidation of malate to oxaloacetate. The enzyme is characterized by its high specificity for NAD+ as a cofactor, allowing it to drive the conversion of malate to oxaloacetate. MDH1 is also notable for its ability to regulate its own activity through allosteric modulation, ensuring that the enzyme's activity is finely tuned to meet the needs of the cell. **Pathways and Functions** MDH1 is involved in several key metabolic pathways, including: 1. **Gluconeogenesis**: MDH1 plays a crucial role in the gluconeogenic pathway, converting malate to oxaloacetate, which can then be converted to glucose through the action of other enzymes. 2. **Glucose Metabolism**: MDH1 is also involved in the regulation of glucose metabolism, influencing the availability of glucose for energy production and storage. 3. **Tricarboxylic Acid Cycle**: MDH1 participates in the tricarboxylic acid cycle, a key metabolic pathway that generates energy for the cell through the oxidation of acetyl-CoA. 4. **NADH Metabolic Process**: MDH1 is also involved in the regulation of NADH levels, influencing the availability of NAD+ for energy production. **Clinical Significance** Dysregulation of MDH1 has been implicated in various diseases, including: 1. **Diabetes**: Alterations in MDH1 activity have been linked to impaired glucose metabolism and insulin resistance, highlighting its potential as a therapeutic target for the treatment of diabetes. 2. **Cancer**: MDH1 has been shown to be overexpressed in certain types of cancer, including breast and lung cancer, suggesting its potential as a biomarker for cancer diagnosis and prognosis. 3. **Neurological Disorders**: MDH1 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease, highlighting its potential as a therapeutic target for the treatment of these conditions. In conclusion, MDH1 is a critical enzyme involved in various metabolic pathways, and its dysregulation has been implicated in various diseases. Further research is needed to fully elucidate the role of MDH1 in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 3647357689

Symbol: MDHC_HUMAN

Name: Cytosolic malate dehydrogenase

UniProtKB Accession Codes:

P40925 B2R5V5 B4DUN2 B7Z3I7 F5H098 Q6I9V0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 3 CPTC 1 CTD 1 ChEBI 20 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EC 2 EMBL 9 Ensembl 3 ExpressionAtlas 1 GO 15 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 2 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 4 Rhea 7 SABIO-RK 1 SIGNOR 1 SMR 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8786100

Title: Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1).

PubMed ID: 8786100

DOI: 10.1006/geno.1996.0087

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7895732

Title: The human myocardial two-dimensional gel protein database: update 1994.

PubMed ID: 7895732

DOI: 10.1002/elps.11501501209

PubMed ID: 2449162

Title: The reduction of aromatic alpha-keto acids by cytoplasmic malate dehydrogenase and lactate dehydrogenase.

PubMed ID: 2449162

DOI: 10.1007/bf00556210

PubMed ID: 3052244

Title: Biochemical and genetic identity of alpha-keto acid reductase and cytoplasmic malate dehydrogenase from human erythrocytes.

PubMed ID: 3052244

DOI: 10.1111/j.1469-1809.1988.tb01075.x

PubMed ID: 16139798

Title: Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.

PubMed ID: 16139798

DOI: 10.1016/j.bbrc.2005.08.132

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22693256

Title: Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity.

PubMed ID: 22693256

DOI: 10.1194/jlr.m026567

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 31538237

Title: MDH1 deficiency is a metabolic disorder of the malate-aspartate shuttle associated with early onset severe encephalopathy.

PubMed ID: 31538237

DOI: 10.1007/s00439-019-02063-z

PubMed ID: 34012073

Title: The metabolite alpha-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.

PubMed ID: 34012073

DOI: 10.1038/s41422-021-00506-9

Sequence Information:

  • Length: 334
  • Mass: 36426
  • Checksum: 5F7ED9789CA1DB55
  • Sequence:
    • MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC 
ALPLLKDVIA TDKEDVAFKD LDVAILVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA 
KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKAQIALK LGVTANDVKN 
VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFVTTVQQR GAAVIKARKL 
SSAMSAAKAI CDHVRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV 
EGLPINDFSR EKMDLTAKEL TEEKESAFEF LSSA

Genular Protein ID: 4060518586

Symbol: A0A5K1VW95_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A5K1VW95

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChEBI 18 DNASU 1 DisGeNET 1 EC 2 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 2 GeneTree 1 HAMAP 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 NCBIfam 2 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PROSITE 1 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 7 RuleBase 2 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 353
  • Mass: 38619
  • Checksum: 796C351071175B34
  • Sequence:
    • MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC 
ALPLLKDVIA TDKEDVAFKD LDVAILVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA 
KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKAQIALK LGVTANDVKN 
VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFVTTVQQR GAAVIKARKL 
SSAMSAAKAI CDHVRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV 
EGLPINDFSR EKMDLTAKEL TEEKESAFEF LSSAXLDNDV TKCFKAEESK CRL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.