Details for: MT2A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 724.0981
Cell Significance Index: -112.6300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 443.0630
Cell Significance Index: -112.3800 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 308.3827
Cell Significance Index: -127.0400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 256.1834
Cell Significance Index: -120.9500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 240.3938
Cell Significance Index: -123.6600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 180.6796
Cell Significance Index: -121.2400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 94.9831
Cell Significance Index: -117.1100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 41.9320
Cell Significance Index: -112.3300 - Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 35.7220
Cell Significance Index: 17.9400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 30.3265
Cell Significance Index: -119.6700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 28.4198
Cell Significance Index: -87.2900 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 25.1909
Cell Significance Index: 445.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 23.8921
Cell Significance Index: -52.2900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 21.5986
Cell Significance Index: 619.1400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 17.1125
Cell Significance Index: 288.2600 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 16.9918
Cell Significance Index: 146.0100 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 11.1802
Cell Significance Index: 68.8100 - Cell Name: perivascular cell (CL4033054)
Fold Change: 8.6480
Cell Significance Index: 39.9300 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 6.9783
Cell Significance Index: 170.2700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 6.7799
Cell Significance Index: 505.3000 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 6.2134
Cell Significance Index: 64.3000 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 6.1309
Cell Significance Index: 41.5400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 5.3247
Cell Significance Index: 250.2600 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 4.4111
Cell Significance Index: 31.6800 - Cell Name: lactocyte (CL0002325)
Fold Change: 3.9996
Cell Significance Index: 516.7300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.9237
Cell Significance Index: 106.8000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 3.3211
Cell Significance Index: 88.9900 - Cell Name: odontoblast (CL0000060)
Fold Change: 2.9260
Cell Significance Index: 375.0900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.7869
Cell Significance Index: 51.5100 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 2.7303
Cell Significance Index: 8.1200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.4510
Cell Significance Index: 64.4500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.0388
Cell Significance Index: 279.9900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.9928
Cell Significance Index: 881.0600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.9682
Cell Significance Index: 29.0500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.7902
Cell Significance Index: 977.6600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.6857
Cell Significance Index: 196.4500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.5011
Cell Significance Index: 24.2200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.4649
Cell Significance Index: 159.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.1806
Cell Significance Index: 83.5000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9509
Cell Significance Index: 188.7000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.8924
Cell Significance Index: 675.4700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.6698
Cell Significance Index: 18.7200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6446
Cell Significance Index: 122.6700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6377
Cell Significance Index: 78.4100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.6251
Cell Significance Index: 106.7400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.4464
Cell Significance Index: 11.1600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4358
Cell Significance Index: 393.4700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.3308
Cell Significance Index: 242.5500 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.1650
Cell Significance Index: 0.9500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0944
Cell Significance Index: 2.5200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0708
Cell Significance Index: 12.7700 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0672
Cell Significance Index: 6.8600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0545
Cell Significance Index: 102.5400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0453
Cell Significance Index: 69.7700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0365
Cell Significance Index: 3.6100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0080
Cell Significance Index: 14.8000 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 0.0072
Cell Significance Index: 0.0800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0365
Cell Significance Index: -4.1800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0447
Cell Significance Index: -60.8100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0734
Cell Significance Index: -5.8100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0803
Cell Significance Index: -51.0000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0812
Cell Significance Index: -60.1300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1243
Cell Significance Index: -77.6500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1405
Cell Significance Index: -79.2300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.2000
Cell Significance Index: -1.6800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.2146
Cell Significance Index: -14.8400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.2293
Cell Significance Index: -104.0700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.2346
Cell Significance Index: -84.1300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2782
Cell Significance Index: -5.4300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2873
Cell Significance Index: -82.6700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.2967
Cell Significance Index: -4.5900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3735
Cell Significance Index: -10.9700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3747
Cell Significance Index: -54.4700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3763
Cell Significance Index: -79.2600 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: -0.3885
Cell Significance Index: -1.8500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4006
Cell Significance Index: -47.2400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.4463
Cell Significance Index: -89.5200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4644
Cell Significance Index: -53.0100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.5114
Cell Significance Index: -3.0900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.6289
Cell Significance Index: -40.5800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.7265
Cell Significance Index: -32.9300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7808
Cell Significance Index: -31.9900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.8136
Cell Significance Index: -26.0600 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: -0.8648
Cell Significance Index: -9.4400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.9241
Cell Significance Index: -46.7000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.9814
Cell Significance Index: -28.2800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.0827
Cell Significance Index: -112.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.1330
Cell Significance Index: -86.9500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.1353
Cell Significance Index: -59.6100 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -1.1619
Cell Significance Index: -13.2000 - Cell Name: epidermal cell (CL0000362)
Fold Change: -1.2730
Cell Significance Index: -2.8700 - Cell Name: mononuclear cell (CL0000842)
Fold Change: -1.3191
Cell Significance Index: -5.4900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -1.3400
Cell Significance Index: -82.3600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.5638
Cell Significance Index: -98.5600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.5737
Cell Significance Index: -23.5800 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: -1.6183
Cell Significance Index: -5.6300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.7341
Cell Significance Index: -116.6000 - Cell Name: hepatoblast (CL0005026)
Fold Change: -1.7379
Cell Significance Index: -29.2300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.7684
Cell Significance Index: -108.4200 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -1.7702
Cell Significance Index: -24.2400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2007106952
Symbol: MT2_HUMAN
Name: Metallothionein-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 913597
Title: Primary structure of human hepatic metallothionein.
PubMed ID: 913597
PubMed ID: 7133118
Title: Human metallothionein genes -- primary structure of the metallothionein-II gene and a related processed gene.
PubMed ID: 7133118
DOI: 10.1038/299797a0
PubMed ID: 6896577
Title: Human metallothionein genes: molecular cloning and sequence analysis of the mRNA.
PubMed ID: 6896577
PubMed ID: 2780570
Title: Changes in brain gene expression shared by scrapie and Alzheimer disease.
PubMed ID: 2780570
PubMed ID: 1339282
Title: Expression of human metallothionein-II fusion protein in Escherichia coli.
PubMed ID: 1339282
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15541360
Title: Identification and characterization of a novel gene EOLA1 stimulating ECV304 cell proliferation.
PubMed ID: 15541360
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 2388267
Title: Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy.
PubMed ID: 2388267
PubMed ID: 1593628
Title: Comparison of the solution conformations of human [Zn7]-metallothionein-2 and [Cd7]-metallothionein-2 using nuclear magnetic resonance spectroscopy.
PubMed ID: 1593628
Sequence Information:
- Length: 61
- Mass: 6042
- Checksum: 7B0A7E1F99843078
- Sequence:
MDPNCSCAAG DSCTCAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCIC KGASDKCSCC A
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.