Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 106.4642
Cell Significance Index: -16.5600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 70.0984
Cell Significance Index: -17.7800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 52.2110
Cell Significance Index: -24.6500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 51.6668
Cell Significance Index: -20.9900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 45.3260
Cell Significance Index: -23.3200 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 36.8393
Cell Significance Index: -24.7200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 22.1945
Cell Significance Index: -21.1900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 17.6243
Cell Significance Index: -21.7300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.3945
Cell Significance Index: -17.1300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.7881
Cell Significance Index: -22.8400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 5.4730
Cell Significance Index: -16.8100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 2.7538
Cell Significance Index: 320.9200 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.2917
Cell Significance Index: 10.8500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2914
Cell Significance Index: 127.7500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.1676
Cell Significance Index: 1054.2600 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.1115
Cell Significance Index: 15.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.0004
Cell Significance Index: 26.7600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.9902
Cell Significance Index: 68.4800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.9499
Cell Significance Index: 44.2900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.9294
Cell Significance Index: 27.3000 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.8454
Cell Significance Index: 6.7500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.7234
Cell Significance Index: 9.8700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.7116
Cell Significance Index: 16.4400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.7104
Cell Significance Index: 13.1300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6363
Cell Significance Index: 17.3200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.6031
Cell Significance Index: 44.9500 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.5977
Cell Significance Index: 6.7900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.5907
Cell Significance Index: 69.6600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5899
Cell Significance Index: 322.1800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.5572
Cell Significance Index: 26.1900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.5554
Cell Significance Index: 19.3000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.5484
Cell Significance Index: 14.4200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5410
Cell Significance Index: 239.1800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5198
Cell Significance Index: 10.8800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.4952
Cell Significance Index: 4.5600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4711
Cell Significance Index: 30.4000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4641
Cell Significance Index: 63.7300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4577
Cell Significance Index: 82.5100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.4363
Cell Significance Index: 30.8600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4096
Cell Significance Index: 50.3700 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3395
Cell Significance Index: 43.8600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3222
Cell Significance Index: 41.3100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.2957
Cell Significance Index: 3.2200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2826
Cell Significance Index: 56.0900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2816
Cell Significance Index: 14.6300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2676
Cell Significance Index: 12.1300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2511
Cell Significance Index: 5.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2442
Cell Significance Index: 15.3900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2221
Cell Significance Index: 5.9300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1860
Cell Significance Index: 5.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1201
Cell Significance Index: 22.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0527
Cell Significance Index: 10.5700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0506
Cell Significance Index: 1.6200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0311
Cell Significance Index: 0.8700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0161
Cell Significance Index: 11.1200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0133
Cell Significance Index: 10.0600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0130
Cell Significance Index: 9.5000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0077
Cell Significance Index: -14.4900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0086
Cell Significance Index: -1.4700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0103
Cell Significance Index: -1.0500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0121
Cell Significance Index: -22.3500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0137
Cell Significance Index: -0.2300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0142
Cell Significance Index: -0.7400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0142
Cell Significance Index: -2.3100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0149
Cell Significance Index: -22.9300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0161
Cell Significance Index: -5.7800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0179
Cell Significance Index: -24.2800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0241
Cell Significance Index: -17.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0302
Cell Significance Index: -19.2000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0360
Cell Significance Index: -20.3300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0423
Cell Significance Index: -1.0800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0446
Cell Significance Index: -5.1100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0476
Cell Significance Index: -29.7300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0494
Cell Significance Index: -22.4200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0688
Cell Significance Index: -19.7900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1172
Cell Significance Index: -24.6800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1183
Cell Significance Index: -2.5200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1229
Cell Significance Index: -17.8600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1618
Cell Significance Index: -8.5000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1884
Cell Significance Index: -14.9200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2030
Cell Significance Index: -15.5800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2069
Cell Significance Index: -5.9300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2184
Cell Significance Index: -22.7400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2566
Cell Significance Index: -14.4000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2771
Cell Significance Index: -17.0300 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -0.2784
Cell Significance Index: -1.7300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3175
Cell Significance Index: -21.3500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.3410
Cell Significance Index: -17.2300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3421
Cell Significance Index: -20.9800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.3920
Cell Significance Index: -9.8000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.4078
Cell Significance Index: -16.7100 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.4081
Cell Significance Index: -4.2300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.4207
Cell Significance Index: -7.4400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4388
Cell Significance Index: -12.9300 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.4448
Cell Significance Index: -2.9000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.4849
Cell Significance Index: -6.2100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4849
Cell Significance Index: -21.4500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.4940
Cell Significance Index: -3.0400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.5143
Cell Significance Index: -18.8800 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.5290
Cell Significance Index: -7.5800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1191172913
Symbol: MTX1_HUMAN
Name: Metaxin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8660965
Title: Structure and organization of the human metaxin gene (MTX) and pseudogene.
PubMed ID: 8660965
PubMed ID: 9331372
Title: Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease.
PubMed ID: 9331372
DOI: 10.1101/gr.7.10.1020
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10381257
Title: Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane.
PubMed ID: 10381257
DOI: 10.1002/(sici)1097-4644(19990701)74:1<11::aid-jcb2>3.3.co;2-m
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22114354
Title: MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization.
PubMed ID: 22114354
PubMed ID: 25997101
Title: QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.
PubMed ID: 25997101
DOI: 10.7554/elife.06265
PubMed ID: 25621951
Title: USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.
PubMed ID: 25621951
DOI: 10.1038/ncb3097
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 31644573
Title: Armadillo repeat-containing protein 1 is a dual localization protein associated with mitochondrial intermembrane space bridging complex.
PubMed ID: 31644573
Sequence Information:
- Length: 466
- Mass: 51463
- Checksum: 2F98ABCA860F50E2
- Sequence:
MLLGGPPRSP RSGTSPKGPW SSTGHVQFGK SPQTWPRRTR PRSPEPAAPS GVRGSTWTRR RDSPRRAGPT ALSRYVGHLW MGRRPPSPEA RGPVPRSSAA SRARRSLASP GISPGPLTAT IGGAVAGGGP RQGRAEAHKE VFPGQRVGKM AAPMELFCWS GGWGLPSVDL DSLAVLTYAR FTGAPLKVHK ISNPWQSPSG TLPALRTSHG EVISVPHKII THLRKEKYNA DYDLSARQGA DTLAFMSLLE EKLLPVLVHT FWIDTKNYVE VTRKWYAEAM PFPLNFFLPG RMQRQYMERL QLLTGEHRPE DEEELEKELY REARECLTLL SQRLGSQKFF FGDAPASLDA FVFSYLALLL QAKLPSGKLQ VHLRGLHNLC AYCTHILSLY FPWDGAEVPP QRQTPAGPET EEEPYRRRNQ ILSVLAGLAA MVGYALLSGI VSIQRATPAR APGTRTLGMA EEDEEE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.