Details for: NACA

Gene ID: 4666

Symbol: NACA

Ensembl ID: ENSG00000196531

Description: nascent polypeptide associated complex subunit alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 1284.8353
    Cell Significance Index: -199.8500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 691.0490
    Cell Significance Index: -175.2800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 618.1854
    Cell Significance Index: -254.6600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 560.6056
    Cell Significance Index: -227.7500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 511.3925
    Cell Significance Index: -241.4400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 488.5443
    Cell Significance Index: -251.3000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 361.1058
    Cell Significance Index: -242.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 244.0971
    Cell Significance Index: -233.0500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 181.6529
    Cell Significance Index: -223.9700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 63.0225
    Cell Significance Index: -248.6900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 62.5030
    Cell Significance Index: -191.9800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 44.7989
    Cell Significance Index: -120.0100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 32.4913
    Cell Significance Index: -71.1100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 11.3563
    Cell Significance Index: 533.7400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 10.5293
    Cell Significance Index: 134.8500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 9.8916
    Cell Significance Index: 283.5500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 9.0809
    Cell Significance Index: 209.8000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 8.4711
    Cell Significance Index: 394.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 8.3601
    Cell Significance Index: 1148.0800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 8.2623
    Cell Significance Index: 1067.4300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 8.0544
    Cell Significance Index: 211.7900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 7.7392
    Cell Significance Index: 547.3500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 7.5270
    Cell Significance Index: 85.5100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 7.4497
    Cell Significance Index: 131.6500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 7.1826
    Cell Significance Index: 496.7100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 7.1678
    Cell Significance Index: 132.4800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 7.0251
    Cell Significance Index: 3105.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 6.9956
    Cell Significance Index: 860.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 6.9339
    Cell Significance Index: 1249.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 6.8753
    Cell Significance Index: 187.1400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 6.8280
    Cell Significance Index: 142.9200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 6.8115
    Cell Significance Index: 74.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 6.8083
    Cell Significance Index: 439.2400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 6.7694
    Cell Significance Index: 504.5200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 6.6609
    Cell Significance Index: 3637.6700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 6.5425
    Cell Significance Index: 227.3500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 5.8755
    Cell Significance Index: 692.9000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 4.8650
    Cell Significance Index: 253.4100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.7271
    Cell Significance Index: 138.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 4.5176
    Cell Significance Index: 579.1300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.9685
    Cell Significance Index: 36.5500
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 3.7316
    Cell Significance Index: 22.9700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.4161
    Cell Significance Index: 179.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 3.1573
    Cell Significance Index: 143.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.1218
    Cell Significance Index: 421.0800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7329
    Cell Significance Index: 46.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.6836
    Cell Significance Index: 87.4600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.5192
    Cell Significance Index: 1371.7200
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.4860
    Cell Significance Index: 8.7300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 1.2380
    Cell Significance Index: 937.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.8763
    Cell Significance Index: 642.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8076
    Cell Significance Index: 153.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5160
    Cell Significance Index: 103.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1363
    Cell Significance Index: 8.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1324
    Cell Significance Index: 47.5000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.1107
    Cell Significance Index: 8.7700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0626
    Cell Significance Index: 1.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0531
    Cell Significance Index: 5.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0170
    Cell Significance Index: -1.7400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0463
    Cell Significance Index: -87.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.1420
    Cell Significance Index: -261.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1724
    Cell Significance Index: -265.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1967
    Cell Significance Index: -33.5900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.2161
    Cell Significance Index: -293.8000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.2837
    Cell Significance Index: -180.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.2933
    Cell Significance Index: -217.2800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.3574
    Cell Significance Index: -247.1900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.3957
    Cell Significance Index: -223.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.4611
    Cell Significance Index: -209.3000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.4778
    Cell Significance Index: -77.7100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.5333
    Cell Significance Index: -333.0500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.7130
    Cell Significance Index: -205.1500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.7277
    Cell Significance Index: -5.8100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7279
    Cell Significance Index: -45.8800
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.7576
    Cell Significance Index: -6.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.9756
    Cell Significance Index: -58.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.9927
    Cell Significance Index: -25.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9951
    Cell Significance Index: -31.8700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.1168
    Cell Significance Index: -31.2100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.3125
    Cell Significance Index: -7.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -1.3198
    Cell Significance Index: -277.9900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.3831
    Cell Significance Index: -161.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.3996
    Cell Significance Index: -34.9800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -1.4507
    Cell Significance Index: -210.8700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.6791
    Cell Significance Index: -94.2200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.6918
    Cell Significance Index: -193.8200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.8899
    Cell Significance Index: -32.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -2.3506
    Cell Significance Index: -244.7500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -2.4143
    Cell Significance Index: -32.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -2.4253
    Cell Significance Index: -186.1200
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -2.5340
    Cell Significance Index: -11.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.5391
    Cell Significance Index: -55.0100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -2.6486
    Cell Significance Index: -45.3900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -3.0856
    Cell Significance Index: -108.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -3.1306
    Cell Significance Index: -210.5000
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -3.3137
    Cell Significance Index: -69.1100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -3.3233
    Cell Significance Index: -88.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -3.3435
    Cell Significance Index: -204.9900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -3.9395
    Cell Significance Index: -59.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -4.6050
    Cell Significance Index: -203.6900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The NACA protein is a subunit of the nascent polypeptide-associated complex (NAC), a protein complex that plays a critical role in protein synthesis and folding. The NACA protein is characterized by its ability to bind to nascent polypeptides, which are newly synthesized proteins, and facilitate their integration into the endoplasmic reticulum (ER) for proper folding and targeting to membranes. The protein's involvement in DNA binding and unfolded protein binding further highlights its role in regulating cellular processes, including transcription, protein homeostasis, and stress response. **Pathways and Functions:** The NACA protein is involved in several key pathways, including: 1. **Protein Synthesis and Folding:** The NACA protein plays a crucial role in protein synthesis and folding by facilitating the integration of nascent polypeptides into the ER. 2. **DNA Binding:** The protein's ability to bind to DNA suggests its potential role in regulating gene expression and transcription. 3. **Protein Targeting to Membranes:** The NACA protein is involved in targeting proteins to membranes, which is essential for various cellular processes, including cell signaling and transport. 4. **Unfolded Protein Binding:** The protein's ability to bind to unfolded proteins suggests its role in regulating protein homeostasis and responding to stress. **Clinical Significance:** The NACA protein's involvement in various cellular processes suggests its potential role in several diseases. For example: 1. **Cancer:** The NACA protein's expression in malignant cells suggests its potential role in cancer progression and metastasis. 2. **Autoimmune Diseases:** The protein's involvement in DNA binding and unfolded protein binding suggests its potential role in autoimmune diseases, such as rheumatoid arthritis and lupus. 3. **Neurological Disorders:** The NACA protein's expression in radial glial cells and fibroblasts of the mammary gland suggests its potential role in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, the NACA protein plays a crucial role in various cellular processes, including protein synthesis and folding, DNA binding, protein targeting to membranes, and unfolded protein binding. Its involvement in these pathways suggests its potential role in several diseases, including cancer, autoimmune diseases, and neurological disorders. Further research is necessary to fully elucidate the role of the NACA protein in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 1443823050

Symbol: NACA_HUMAN

Name: Nascent polypeptide-associated complex subunit alpha

UniProtKB Accession Codes:

Q13765 A8MTN7 B2R4P8 F8VU71 Q3KQV4 Q53A18 Q53G46

Database IDs:

AGR 1 Allergome 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 EMDB 4 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 IntAct 1 InterPro 4 KEGG 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PIRSF 1 PROSITE 1 PathwayCommons 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RefSeq 6 SIGNOR 1 SMART 1 SMR 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12209604

Title: Novel products of the HuD, HuC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library.

PubMed ID: 12209604

DOI: 10.1002/ijc.10550

PubMed ID: 15196207

Title: Investigation of alpha nascent polypeptide-associated complex functions in a human CD8(+) T cell ex vivo expansion model using antisense oligonucleotides.

PubMed ID: 15196207

DOI: 10.1111/j.1365-2567.2004.01893.x

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9806765

Title: Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.

PubMed ID: 9806765

DOI: 10.1096/fasebj.12.14.1559

PubMed ID: 9877153

Title: Unregulated exposure of the ribosomal M-site caused by NAC depletion results in delivery of non-secretory polypeptides to the Sec61 complex.

PubMed ID: 9877153

DOI: 10.1016/s0014-5793(98)01440-9

PubMed ID: 10982809

Title: The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functions.

PubMed ID: 10982809

DOI: 10.1074/jbc.m006368200

PubMed ID: 12684039

Title: The alpha-chain of the nascent polypeptide-associated complex binds to and regulates FADD function.

PubMed ID: 12684039

DOI: 10.1016/s0006-291x(03)00487-x

PubMed ID: 12689679

Title: Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas.

PubMed ID: 12689679

DOI: 10.1016/s8756-3282(03)00026-7

PubMed ID: 15299025

Title: Integrin-linked kinase regulates the nuclear entry of the c-Jun coactivator alpha-NAC and its coactivation potency.

PubMed ID: 15299025

DOI: 10.1074/jbc.m406310200

PubMed ID: 15784678

Title: NACA is a positive regulator of human erythroid-cell differentiation.

PubMed ID: 15784678

DOI: 10.1242/jcs.02295

PubMed ID: 16201836

Title: Emergence of young human genes after a burst of retroposition in primates.

PubMed ID: 16201836

DOI: 10.1371/journal.pbio.0030357

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 20214399

Title: The crystal structure of the human nascent polypeptide-associated complex domain reveals a nucleic acid-binding region on the NACA subunit.

PubMed ID: 20214399

DOI: 10.1021/bi902050p

PubMed ID: 21203952

Title: Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit.

PubMed ID: 21203952

DOI: 10.1007/s13238-010-0049-3

Sequence Information:

  • Length: 215
  • Mass: 23384
  • Checksum: 05DC563A8BEF307C
  • Sequence:
    • MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID 
EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY 
IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETGVEVKD 
IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.