Details for: NUCB1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 344.3372
Cell Significance Index: -53.5600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 200.4389
Cell Significance Index: -50.8400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 135.4315
Cell Significance Index: -55.0200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 130.5275
Cell Significance Index: -61.6300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 118.8895
Cell Significance Index: -61.1600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 92.1356
Cell Significance Index: -61.8300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 58.3089
Cell Significance Index: -55.6700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 46.7413
Cell Significance Index: -57.6300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.1831
Cell Significance Index: -48.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.3369
Cell Significance Index: -60.5200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 13.6515
Cell Significance Index: -41.9300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.0025
Cell Significance Index: -24.0800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 4.4817
Cell Significance Index: 37.6500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.6603
Cell Significance Index: 138.5700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.4695
Cell Significance Index: 43.6400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.1894
Cell Significance Index: 64.3000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.6868
Cell Significance Index: 231.6500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.6770
Cell Significance Index: 78.1900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 1.2183
Cell Significance Index: 13.8400 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.1676
Cell Significance Index: 149.6800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9934
Cell Significance Index: 542.5000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9778
Cell Significance Index: 882.9200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.9216
Cell Significance Index: 19.2900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8976
Cell Significance Index: 110.3700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.8330
Cell Significance Index: 150.1600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.7661
Cell Significance Index: 14.1600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.7472
Cell Significance Index: 55.6900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.7062
Cell Significance Index: 15.3000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6753
Cell Significance Index: 134.0300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.6162
Cell Significance Index: 79.6100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6067
Cell Significance Index: 121.7000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5371
Cell Significance Index: 14.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5229
Cell Significance Index: 23.7000 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.5072
Cell Significance Index: 4.0500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4909
Cell Significance Index: 217.0200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.4693
Cell Significance Index: 24.6400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4597
Cell Significance Index: 23.8800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4583
Cell Significance Index: 13.2100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4406
Cell Significance Index: 71.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3936
Cell Significance Index: 18.5000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3764
Cell Significance Index: 64.2700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3744
Cell Significance Index: 24.1600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3272
Cell Significance Index: 22.6300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.3230
Cell Significance Index: 8.6600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3083
Cell Significance Index: 58.6700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2900
Cell Significance Index: 20.5100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2697
Cell Significance Index: 96.7500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2202
Cell Significance Index: 5.7900 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.2182
Cell Significance Index: 2.7900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1606
Cell Significance Index: 111.0900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1207
Cell Significance Index: 14.2300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0980
Cell Significance Index: 1.6400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.0934
Cell Significance Index: 0.8600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0556
Cell Significance Index: 42.0900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0231
Cell Significance Index: 2.2900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0062
Cell Significance Index: 11.7000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0021
Cell Significance Index: 0.0600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0003
Cell Significance Index: -0.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0079
Cell Significance Index: -5.8000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0105
Cell Significance Index: -0.2800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0199
Cell Significance Index: -14.7400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0227
Cell Significance Index: -41.7800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0285
Cell Significance Index: -2.1900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0327
Cell Significance Index: -50.3400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0405
Cell Significance Index: -25.2800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0478
Cell Significance Index: -65.0200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0665
Cell Significance Index: -42.2100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0740
Cell Significance Index: -41.7600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0856
Cell Significance Index: -38.8700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1452
Cell Significance Index: -30.5800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1604
Cell Significance Index: -18.3800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1676
Cell Significance Index: -5.8900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1701
Cell Significance Index: -48.9500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2793
Cell Significance Index: -40.6100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3055
Cell Significance Index: -35.6000 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3398
Cell Significance Index: -7.8500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4484
Cell Significance Index: -51.1900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4599
Cell Significance Index: -14.7300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4870
Cell Significance Index: -13.6100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.5077
Cell Significance Index: -12.9700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.5504
Cell Significance Index: -33.8300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5518
Cell Significance Index: -57.4600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.6133
Cell Significance Index: -41.2400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6971
Cell Significance Index: -55.2100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.6987
Cell Significance Index: -24.2800 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.7085
Cell Significance Index: -10.7600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7224
Cell Significance Index: -40.5400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7492
Cell Significance Index: -47.2200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8524
Cell Significance Index: -22.8000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.8783
Cell Significance Index: -13.1600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.8793
Cell Significance Index: -21.9800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9181
Cell Significance Index: -56.2900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.9307
Cell Significance Index: -9.6400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.9443
Cell Significance Index: -18.4300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.0109
Cell Significance Index: -51.0900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.1172
Cell Significance Index: -49.4200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.1330
Cell Significance Index: -24.1300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.1978
Cell Significance Index: -17.6800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -1.2811
Cell Significance Index: -52.4900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.3013
Cell Significance Index: -38.3300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3294992711
Symbol: NUCB1_HUMAN
Name: Nucleobindin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1520323
Title: Molecular cloning of nucleobindin, a novel DNA-binding protein that contains both a signal peptide and a leucine zipper structure.
PubMed ID: 1520323
PubMed ID: 8661046
Title: Organization of the human gene for nucleobindin (NUC) and its chromosomal assignment to 19q13.2-q13.4.
PubMed ID: 8661046
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7589456
Title: Interaction of the protein nucleobindin with G alpha i2, as revealed by the yeast two-hybrid system.
PubMed ID: 7589456
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 23234360
Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.
PubMed ID: 23234360
DOI: 10.1021/pr300963h
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 30194280
Title: A biochemical and genetic discovery pipeline identifies PLCdelta4b as a nonreceptor activator of heterotrimeric G-proteins.
PubMed ID: 30194280
PubMed ID: 15287731
Title: Structural studies on the Ca2+-binding domain of human nucleobindin (Calnuc).
PubMed ID: 15287731
DOI: 10.1021/bi049310a
Sequence Information:
- Length: 461
- Mass: 53879
- Checksum: 913C4B87C2A644C5
- Sequence:
MPPSGPRGTL LLLPLLLLLL LRAVLAVPLE RGAPNKEETP ATESPDTGLY YHRYLQEVID VLETDGHFRE KLQAANAEDI KSGKLSRELD FVSHHVRTKL DELKRQEVSR LRMLLKAKMD AEQDPNVQVD HLNLLKQFEH LDPQNQHTFE ARDLELLIQT ATRDLAQYDA AHHEEFKRYE MLKEHERRRY LESLGEEQRK EAERKLEEQQ RRHREHPKVN VPGSQAQLKE VWEELDGLDP NRFNPKTFFI LHDINSDGVL DEQELEALFT KELEKVYDPK NEEDDMREME EERLRMREHV MKNVDTNQDR LVTLEEFLAS TQRKEFGDTG EGWETVEMHP AYTEEELRRF EEELAAREAE LNAKAQRLSQ ETEALGRSQG RLEAQKRELQ QAVLHMEQRK QQQQQQQGHK APAAHPEGQL KFHPDTDDVP VPAPAGDQKE VDTSEKKLLE RLPEVEVPQH L
Genular Protein ID: 1745732760
Symbol: A8K7Q1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 461
- Mass: 53883
- Checksum: DBDC44392B5562E2
- Sequence:
MPPSGPRGTL LLLPLLLLLL LRAVLAVPLE RGAPNKEETP ATESPDTGLY YHRYLQEVID VLETDGHFRE KLQAANAEDI KSGKLSRELD FVSHHVRTKL DELKRQEVSR LRMLLKAKMD AEQDPNVQVD HLNLLKQFEH LDPQNQHTFE ARDLELLIQT ATRDLAQYDA AHHEEFKRYE MLKEHERRRY LESLGEEQRK EAERKLEEQQ RRHREHPKVN VPGSQAQLKE VWEELDGLDP NRFNPKTFFI LHDINSDGVL DEQELEALFT KELEKVHDPK NEEDDMREME EERLRMWEHV MKNVDTNQDR LVTLEEFLAS TQRKEFGDTG EGWETVEMHP AYTEEELRRF EEELAAREAE LNAKAQRLSQ ETEALGRSQG RLEAQKRELQ QAVLHMEQRK QQQQQQQGHK APAAHPEGQL KFHPDTDDVP VPAPAGDQKE VDTSEKKLLE RLPEVEVPQH L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.