Details for: EIF3L

Gene ID: 51386

Symbol: EIF3L

Ensembl ID: ENSG00000100129

Description: eukaryotic translation initiation factor 3 subunit L

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 440.1292
    Cell Significance Index: -68.4600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 220.3678
    Cell Significance Index: -90.7800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 203.2457
    Cell Significance Index: -82.5700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 197.2257
    Cell Significance Index: -50.0300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 187.4937
    Cell Significance Index: -88.5200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 181.3038
    Cell Significance Index: -93.2600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 132.3205
    Cell Significance Index: -88.7900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 88.0551
    Cell Significance Index: -84.0700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 67.9668
    Cell Significance Index: -83.8000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 22.8456
    Cell Significance Index: -90.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.9960
    Cell Significance Index: -45.5300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 16.3017
    Cell Significance Index: -50.0700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.1984
    Cell Significance Index: -22.3200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 8.0910
    Cell Significance Index: 87.9600
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 7.1607
    Cell Significance Index: 57.1700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 7.0606
    Cell Significance Index: 147.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 6.1478
    Cell Significance Index: 164.4500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 5.6127
    Cell Significance Index: 71.8800
  • Cell Name: theca cell (CL0000503)
    Fold Change: 5.0774
    Cell Significance Index: 29.8300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 4.9553
    Cell Significance Index: 640.1900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 4.8675
    Cell Significance Index: 169.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 4.7967
    Cell Significance Index: 126.1300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 4.6884
    Cell Significance Index: 82.8500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 3.8080
    Cell Significance Index: 269.3200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.6838
    Cell Significance Index: 274.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.4401
    Cell Significance Index: 472.4200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.3939
    Cell Significance Index: 218.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.1782
    Cell Significance Index: 149.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 3.1434
    Cell Significance Index: 146.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.1217
    Cell Significance Index: 368.1400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.7321
    Cell Significance Index: 1207.9400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.6961
    Cell Significance Index: 79.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.6647
    Cell Significance Index: 327.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.5515
    Cell Significance Index: 435.6800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.5454
    Cell Significance Index: 69.2900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.2464
    Cell Significance Index: 1226.8400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.1577
    Cell Significance Index: 113.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.0052
    Cell Significance Index: 361.4800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7503
    Cell Significance Index: 23.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.5246
    Cell Significance Index: 195.4500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1828
    Cell Significance Index: 234.7400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.7741
    Cell Significance Index: 40.3200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7427
    Cell Significance Index: 38.5800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6674
    Cell Significance Index: 133.8900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.5739
    Cell Significance Index: 6.5200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5707
    Cell Significance Index: 15.9500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4940
    Cell Significance Index: 94.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4798
    Cell Significance Index: 13.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4349
    Cell Significance Index: 43.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2776
    Cell Significance Index: 99.5900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1966
    Cell Significance Index: 5.6400
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.1874
    Cell Significance Index: 1.4100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1514
    Cell Significance Index: 114.5600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1486
    Cell Significance Index: 4.7600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1087
    Cell Significance Index: 1.8200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1025
    Cell Significance Index: 92.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0471
    Cell Significance Index: 34.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0088
    Cell Significance Index: 16.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0090
    Cell Significance Index: -6.6800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0125
    Cell Significance Index: -0.4400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0184
    Cell Significance Index: -33.9800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0192
    Cell Significance Index: -1.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0314
    Cell Significance Index: -48.3700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0442
    Cell Significance Index: -1.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0454
    Cell Significance Index: -28.3800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0493
    Cell Significance Index: -67.0800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0503
    Cell Significance Index: -0.9300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0912
    Cell Significance Index: -57.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0951
    Cell Significance Index: -53.6500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1440
    Cell Significance Index: -65.3400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1498
    Cell Significance Index: -31.5600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1703
    Cell Significance Index: -27.6900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1789
    Cell Significance Index: -20.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2167
    Cell Significance Index: -25.2500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2513
    Cell Significance Index: -6.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2678
    Cell Significance Index: -77.0500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3553
    Cell Significance Index: -19.9400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.3952
    Cell Significance Index: -2.4500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4157
    Cell Significance Index: -25.5500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4202
    Cell Significance Index: -10.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4459
    Cell Significance Index: -51.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4484
    Cell Significance Index: -34.4100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4490
    Cell Significance Index: -65.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5288
    Cell Significance Index: -33.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5618
    Cell Significance Index: -28.3900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6344
    Cell Significance Index: -13.5100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.6689
    Cell Significance Index: -6.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6771
    Cell Significance Index: -53.6300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7553
    Cell Significance Index: -18.8800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8140
    Cell Significance Index: -84.7600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.8169
    Cell Significance Index: -54.9300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.8853
    Cell Significance Index: -19.1800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.9760
    Cell Significance Index: -39.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.0136
    Cell Significance Index: -17.3700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.0157
    Cell Significance Index: -10.5200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.0245
    Cell Significance Index: -23.6700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.0277
    Cell Significance Index: -46.5800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.1471
    Cell Significance Index: -68.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2118
    Cell Significance Index: -74.3000
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -1.3152
    Cell Significance Index: -7.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of eIF3 complex**: EIF3L is a subunit of the eIF3 complex, which is a crucial component of the eukaryotic translation initiation complex. 2. **Cap-binding complex and eIFs interaction**: EIF3L interacts with the cap-binding complex and eIFs to activate mRNA upon binding. 3. **Binding to 43S ribosomal subunit**: EIF3L binds to the 43S ribosomal subunit, which is essential for the initiation of protein synthesis. 4. **Significant expression in various cell types**: EIF3L is significantly expressed in hematopoietic progenitor cells, embryonic stem cells, and smooth muscle fibers. **Pathways and Functions:** 1. **Activation of mRNA**: EIF3L plays a crucial role in the activation of mRNA upon binding of the cap-binding complex and eIFs. 2. **Binding to 43S ribosomal subunit**: EIF3L binds to the 43S ribosomal subunit, which is essential for the initiation of protein synthesis. 3. **Translation initiation**: EIF3L is involved in the translation initiation process, which is the first step in protein synthesis. 4. **Regulation of protein expression**: EIF3L regulates the expression of proteins by controlling the translation initiation process. **Clinical Significance:** EIF3L plays a crucial role in various cellular processes, including protein synthesis, cell proliferation, and differentiation. Dysregulation of EIF3L has been implicated in various diseases, including: 1. **Ceruloplasmin expression**: EIF3L-mediated translational silencing of ceruloplasmin expression has been implicated in Wilson's disease, a genetic disorder characterized by copper accumulation in the body. 2. **Hematological disorders**: EIF3L is significantly expressed in hematopoietic progenitor cells, and dysregulation of EIF3L has been implicated in various hematological disorders, including leukemia and lymphoma. 3. **Neurological disorders**: EIF3L has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease, due to its role in protein synthesis and degradation. In conclusion, EIF3L is a crucial component of the eukaryotic translation initiation complex, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the role of EIF3L in eukaryotic translation initiation and its clinical significance.

Genular Protein ID: 2701695674

Symbol: EIF3L_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9Y262 B2RDG6 B4DYB2 G8JLH4 Q53HQ1 Q53HT4 Q5QTR1 Q5TI15 Q6ICD2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 EMDB 12 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 6 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11590142

Title: The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3.

PubMed ID: 11590142

DOI: 10.1074/jbc.m104966200

PubMed ID: 12393749

Title: Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter.

PubMed ID: 12393749

DOI: 10.1093/embo-reports/kvf212

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15703437

Title: Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.

PubMed ID: 15703437

DOI: 10.1261/rna.7215305

PubMed ID: 16766523

Title: Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.

PubMed ID: 16766523

DOI: 10.1074/jbc.m605418200

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 18056426

Title: The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation.

PubMed ID: 18056426

DOI: 10.1101/gad.439507

PubMed ID: 17322308

Title: Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

PubMed ID: 17322308

DOI: 10.1074/mcp.m600399-mcp200

PubMed ID: 18599441

Title: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

PubMed ID: 18599441

DOI: 10.1073/pnas.0801313105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25849773

Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.

PubMed ID: 25849773

DOI: 10.1038/nature14267

PubMed ID: 27462815

Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

PubMed ID: 27462815

DOI: 10.1038/nature18954

PubMed ID: 16322461

Title: Structural roles for human translation factor eIF3 in initiation of protein synthesis.

PubMed ID: 16322461

DOI: 10.1126/science.1118977

Sequence Information:

  • Length: 564
  • Mass: 66727
  • Checksum: ECBD32192D96E3FE
  • Sequence:
    • MSYPADDYES EAAYDPYAYP SDYDMHTGDP KQDLAYERQY EQQTYQVIPE VIKNFIQYFH 
KTVSDLIDQK VYELQASRVS SDVIDQKVYE IQDIYENSWT KLTERFFKNT PWPEAEAIAP 
QVGNDAVFLI LYKELYYRHI YAKVSGGPSL EQRFESYYNY CNLFNYILNA DGPAPLELPN 
QWLWDIIDEF IYQFQSFSQY RCKTAKKSEE EIDFLRSNPK IWNVHSVLNV LHSLVDKSNI 
NRQLEVYTSG GDPESVAGEY GRHSLYKMLG YFSLVGLLRL HSLLGDYYQA IKVLENIELN 
KKSMYSRVPE CQVTTYYYVG FAYLMMRRYQ DAIRVFANIL LYIQRTKSMF QRTTYKYEMI 
NKQNEQMHAL LAIALTMYPM RIDESIHLQL REKYGDKMLR MQKGDPQVYE ELFSYSCPKF 
LSPVVPNYDN VHPNYHKEPF LQQLKVFSDE VQQQAQLSTI RSFLKLYTTM PVAKLAGFLD 
LTEQEFRIQL LVFKHKMKNL VWTSGISALD GEFQSASEVD FYIDKDMIHI ADTKVARRYG 
DFFIRQIHKF EELNRTLKKM GQRP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.