Details for: PDHB

Gene ID: 5162

Symbol: PDHB

Ensembl ID: ENSG00000168291

Description: pyruvate dehydrogenase E1 subunit beta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 210.9354
    Cell Significance Index: -32.8100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 112.4413
    Cell Significance Index: -28.5200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 99.6729
    Cell Significance Index: -41.0600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 83.1140
    Cell Significance Index: -39.2400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 78.9402
    Cell Significance Index: -32.0700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 72.9609
    Cell Significance Index: -37.5300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 58.7015
    Cell Significance Index: -39.3900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.0720
    Cell Significance Index: -32.5300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 30.3742
    Cell Significance Index: -37.4500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.8047
    Cell Significance Index: -38.6900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.6627
    Cell Significance Index: -25.8900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.9832
    Cell Significance Index: -24.5200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.0581
    Cell Significance Index: -11.0700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.9150
    Cell Significance Index: 15.2900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2230
    Cell Significance Index: 32.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.1911
    Cell Significance Index: 31.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1014
    Cell Significance Index: 601.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.0936
    Cell Significance Index: 75.6300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9015
    Cell Significance Index: 12.3000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.8738
    Cell Significance Index: 18.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8670
    Cell Significance Index: 106.6100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8235
    Cell Significance Index: 148.4600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8104
    Cell Significance Index: 103.8900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7833
    Cell Significance Index: 27.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7554
    Cell Significance Index: 103.7400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6840
    Cell Significance Index: 31.8900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6716
    Cell Significance Index: 6.1900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6283
    Cell Significance Index: 6.8300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6164
    Cell Significance Index: 32.0200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6139
    Cell Significance Index: 43.4200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6063
    Cell Significance Index: 39.1200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5973
    Cell Significance Index: 70.4500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5959
    Cell Significance Index: 96.9300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5687
    Cell Significance Index: 251.4400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5662
    Cell Significance Index: 29.4900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5504
    Cell Significance Index: 16.1700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5116
    Cell Significance Index: 23.1900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4061
    Cell Significance Index: 80.5900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2961
    Cell Significance Index: 59.3900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2725
    Cell Significance Index: 7.8500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2543
    Cell Significance Index: 25.1600
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.2477
    Cell Significance Index: 1.8700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2284
    Cell Significance Index: 43.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2065
    Cell Significance Index: 26.6800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.1593
    Cell Significance Index: 1.8100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1547
    Cell Significance Index: 7.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1509
    Cell Significance Index: 4.0300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1406
    Cell Significance Index: 8.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1367
    Cell Significance Index: 49.0500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1221
    Cell Significance Index: 6.4100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1050
    Cell Significance Index: 17.9300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0757
    Cell Significance Index: 5.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0642
    Cell Significance Index: 47.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0470
    Cell Significance Index: 1.2800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0417
    Cell Significance Index: 28.8600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0239
    Cell Significance Index: 0.5100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0212
    Cell Significance Index: 0.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0037
    Cell Significance Index: 2.7700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.8200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0054
    Cell Significance Index: -0.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0072
    Cell Significance Index: -13.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0119
    Cell Significance Index: -18.3400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0153
    Cell Significance Index: -11.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0173
    Cell Significance Index: -10.9700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0204
    Cell Significance Index: -27.7600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0205
    Cell Significance Index: -12.8100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0436
    Cell Significance Index: -1.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0450
    Cell Significance Index: -25.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0466
    Cell Significance Index: -4.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0566
    Cell Significance Index: -25.6800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0742
    Cell Significance Index: -15.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0906
    Cell Significance Index: -10.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1026
    Cell Significance Index: -29.5200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1366
    Cell Significance Index: -4.8000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1515
    Cell Significance Index: -3.8700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1628
    Cell Significance Index: -18.5800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1684
    Cell Significance Index: -13.3400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1769
    Cell Significance Index: -20.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1829
    Cell Significance Index: -26.5900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1955
    Cell Significance Index: -2.3300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2131
    Cell Significance Index: -16.3600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2619
    Cell Significance Index: -7.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2680
    Cell Significance Index: -15.0400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2743
    Cell Significance Index: -16.8600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.3250
    Cell Significance Index: -2.7300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3509
    Cell Significance Index: -2.1200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3516
    Cell Significance Index: -7.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3676
    Cell Significance Index: -38.2800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4114
    Cell Significance Index: -7.2700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4357
    Cell Significance Index: -29.3000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4549
    Cell Significance Index: -14.5700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4729
    Cell Significance Index: -8.7400
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.4840
    Cell Significance Index: -3.0300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4926
    Cell Significance Index: -14.5100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.5575
    Cell Significance Index: -7.1400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5873
    Cell Significance Index: -14.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6311
    Cell Significance Index: -38.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6552
    Cell Significance Index: -28.9800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.7718
    Cell Significance Index: -7.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7896
    Cell Significance Index: -29.9000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of the PDH Complex:** PDHB is a subunit of the PDH complex, which consists of three components: pyruvate dehydrogenase E1 (PDK1), pyruvate dehydrogenase E2 (PDK2), and dihydrolipoyl transacetylase (DHT). 2. **Mitochondrial Localization:** PDHB is a mitochondrial protein, specifically localized to the mitochondrial matrix. 3. **Regulatory Function:** PDHB acts as a regulatory subunit, modulating the activity of the PDH complex in response to various cellular signals. 4. **Cellular Expression:** PDHB is expressed in various cell types, including erythroid progenitor cells, placental trophoblasts, kidney collecting duct intercalated cells, and epithelial cells of the esophagus. **Pathways and Functions:** 1. **Pyruvate Metabolism:** PDHB is involved in the conversion of pyruvate to acetyl-CoA, a critical step in cellular energy metabolism. 2. **Citric Acid Cycle:** PDHB plays a role in the regulation of the citric acid cycle (TCA cycle) and respiratory electron transport. 3. **Glyoxylate Metabolism:** PDHB is also involved in glyoxylate metabolism and glycine degradation. 4. **Amino Acid Metabolism:** PDHB is involved in the metabolism of amino acids and derivatives. **Clinical Significance:** Dysregulation of PDHB has been implicated in various diseases, including: 1. **Metabolic Disorders:** PDHB mutations have been associated with metabolic disorders, such as mitochondrial myopathies and diabetic ketoacidosis. 2. **Cancer:** PDHB overexpression has been observed in certain types of cancer, suggesting a potential role in tumorigenesis. 3. **Neurological Disorders:** PDHB has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, PDHB is a crucial component of the PDH complex, playing a pivotal role in regulating cellular energy metabolism. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the functions and clinical significance of this gene.

Genular Protein ID: 2735085847

Symbol: ODPB_HUMAN

Name: Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

UniProtKB Accession Codes:

P11177 B2R7L0 B4DDD7 Q6FH45 Q9BQ27 Q9UFK3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CPTAC 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 2 EMBL 16 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 4 RefSeq 3 Rhea 3 SABIO-RK 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2323578

Title: Cloning and cDNA sequence of the beta-subunit component of human pyruvate dehydrogenase complex.

PubMed ID: 2323578

DOI: 10.1016/0378-1119(90)90294-2

PubMed ID: 1702713

Title: Isolation, characterization and chromosomal localization of cDNA clones for the E1 beta subunit of the pyruvate dehydrogenase complex.

PubMed ID: 1702713

DOI: 10.1111/j.1432-1033.1990.tb15656.x

PubMed ID: 2376596

Title: Characterization of two cDNA clones for pyruvate dehydrogenase E1 beta subunit and its regulation in tricarboxylic acid cycle-deficient fibroblast.

PubMed ID: 2376596

DOI: 10.1016/s0021-9258(19)38301-2

PubMed ID: 2377599

Title: Molecular cloning and characterization of human pyruvate dehydrogenase beta subunit gene.

PubMed ID: 2377599

DOI: 10.1073/pnas.87.15.5594

PubMed ID: 3422424

Title: Cloning and sequencing of cDNAs encoding alpha and beta subunits of human pyruvate dehydrogenase.

PubMed ID: 3422424

DOI: 10.1073/pnas.85.1.41

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2829898

Title: Identification of a cDNA clone for the beta-subunit of the pyruvate dehydrogenase component of human pyruvate dehydrogenase complex.

PubMed ID: 2829898

DOI: 10.1016/0006-291x(88)90714-0

PubMed ID: 7895732

Title: The human myocardial two-dimensional gel protein database: update 1994.

PubMed ID: 7895732

DOI: 10.1002/elps.11501501209

PubMed ID: 2295468

Title: Isolation of tryptic fragment of antigen from mitochondrial inner membrane proteins reacting with antimitochondrial antibody in sera of patients with primary biliary cirrhosis.

PubMed ID: 2295468

DOI: 10.1002/hep.1840110105

PubMed ID: 14638692

Title: Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components.

PubMed ID: 14638692

DOI: 10.1074/jbc.m308172200

PubMed ID: 20160912

Title: Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex.

PubMed ID: 20160912

DOI: 10.1016/j.molcatb.2009.05.001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 12651851

Title: Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase.

PubMed ID: 12651851

DOI: 10.1074/jbc.m300339200

PubMed ID: 17474719

Title: Phosphorylation of serine 264 impedes active site accessibility in the E1 component of the human pyruvate dehydrogenase multienzyme complex.

PubMed ID: 17474719

DOI: 10.1021/bi700083z

PubMed ID: 19081061

Title: Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.

PubMed ID: 19081061

DOI: 10.1016/j.str.2008.10.010

PubMed ID: 29970614

Title: Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the alphaV138M variant of human pyruvate dehydrogenase.

PubMed ID: 29970614

DOI: 10.1074/jbc.ra118.003996

PubMed ID: 15138885

Title: Mutations in the gene for the E1beta subunit: a novel cause of pyruvate dehydrogenase deficiency.

PubMed ID: 15138885

DOI: 10.1007/s00439-004-1124-8

Sequence Information:

  • Length: 359
  • Mass: 39233
  • Checksum: AB459B1259FBDBD3
  • Sequence:
    • MAAVSGLVRR PLREVSGLLK RRFHWTAPAA LQVTVRDAIN QGMDEELERD EKVFLLGEEV 
AQYDGAYKVS RGLWKKYGDK RIIDTPISEM GFAGIAVGAA MAGLRPICEF MTFNFSMQAI 
DQVINSAAKT YYMSGGLQPV PIVFRGPNGA SAGVAAQHSQ CFAAWYGHCP GLKVVSPWNS 
EDAKGLIKSA IRDNNPVVVL ENELMYGVPF EFPPEAQSKD FLIPIGKAKI ERQGTHITVV 
SHSRPVGHCL EAAAVLSKEG VECEVINMRT IRPMDMETIE ASVMKTNHLV TVEGGWPQFG 
VGAEICARIM EGPAFNFLDA PAVRVTGADV PMPYAKILED NSIPQVKDII FAIKKTLNI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.