POLR2F | ENSG00000100142 | NCBI 5435

Details for: POLR2F

Gene ID: 5435

Symbol: POLR2F

Ensembl ID: ENSG00000100142

Description: RNA polymerase II, I and III subunit F

Associated with

Abortive elongation of hiv-1 transcript in the absence of tat
(R-HSA-167242)
Activation of anterior hox genes in hindbrain development during early embryogenesis
(R-HSA-5617472)
Activation of hox genes during differentiation
(R-HSA-5619507)
B-wich complex positively regulates rrna expression
(R-HSA-5250924)
Cell cycle
(R-HSA-1640170)
Chromosome maintenance
(R-HSA-73886)
Cytosolic sensors of pathogen-associated dna
(R-HSA-1834949)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Dna repair
(R-HSA-73894)
Dual incision in tc-ner
(R-HSA-6782135)
Epigenetic regulation of gene expression
(R-HSA-212165)
Esr-mediated signaling
(R-HSA-8939211)
Estrogen-dependent gene expression
(R-HSA-9018519)
Fgfr2 alternative splicing
(R-HSA-6803529)
Fgfr2 mutant receptor activation
(R-HSA-1839126)
Formation of hiv-1 elongation complex containing hiv-1 tat
(R-HSA-167200)
Formation of hiv elongation complex in the absence of hiv tat
(R-HSA-167152)
Formation of rna pol ii elongation complex
(R-HSA-112382)
Formation of tc-ner pre-incision complex
(R-HSA-6781823)
Formation of the early elongation complex
(R-HSA-113418)
Formation of the hiv-1 early elongation complex
(R-HSA-167158)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-HSA-6782210)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Gene silencing by rna
(R-HSA-211000)
Hiv elongation arrest and recovery
(R-HSA-167287)
Hiv infection
(R-HSA-162906)
Hiv life cycle
(R-HSA-162587)
Hiv transcription elongation
(R-HSA-167169)
Hiv transcription initiation
(R-HSA-167161)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
Inhibition of dna recombination at telomere
(R-HSA-9670095)
Innate immune system
(R-HSA-168249)
Late phase of hiv life cycle
(R-HSA-162599)
Metabolism of rna
(R-HSA-8953854)
Microrna (mirna) biogenesis
(R-HSA-203927)
Mrna capping
(R-HSA-72086)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Mrna splicing - minor pathway
(R-HSA-72165)
Negative epigenetic regulation of rrna expression
(R-HSA-5250941)
Norc negatively regulates rrna expression
(R-HSA-427413)
Nucleotide excision repair
(R-HSA-5696398)
Pausing and recovery of hiv elongation
(R-HSA-167290)
Pausing and recovery of tat-mediated hiv elongation
(R-HSA-167238)
Piwi-interacting rna (pirna) biogenesis
(R-HSA-5601884)
Positive epigenetic regulation of rrna expression
(R-HSA-5250913)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Rna pol ii ctd phosphorylation and interaction with ce
(R-HSA-77075)
Rna pol ii ctd phosphorylation and interaction with ce during hiv infection
(R-HSA-167160)
Rna polymerase ii hiv promoter escape
(R-HSA-167162)
Rna polymerase iii abortive and retractive initiation
(R-HSA-749476)
Rna polymerase iii chain elongation
(R-HSA-73780)
Rna polymerase iii transcription
(R-HSA-74158)
Rna polymerase iii transcription initiation
(R-HSA-76046)
Rna polymerase iii transcription initiation from type 1 promoter
(R-HSA-76061)
Rna polymerase iii transcription initiation from type 2 promoter
(R-HSA-76066)
Rna polymerase iii transcription initiation from type 3 promoter
(R-HSA-76071)
Rna polymerase iii transcription termination
(R-HSA-73980)
Rna polymerase ii pre-transcription events
(R-HSA-674695)
Rna polymerase ii promoter escape
(R-HSA-73776)
Rna polymerase ii transcribes snrna genes
(R-HSA-6807505)
Rna polymerase ii transcription
(R-HSA-73857)
Rna polymerase ii transcription elongation
(R-HSA-75955)
Rna polymerase ii transcription initiation
(R-HSA-75953)
Rna polymerase ii transcription initiation and promoter clearance
(R-HSA-76042)
Rna polymerase ii transcription pre-initiation and promoter opening
(R-HSA-73779)
Rna polymerase i promoter clearance
(R-HSA-73854)
Rna polymerase i promoter escape
(R-HSA-73772)
Rna polymerase i transcription
(R-HSA-73864)
Rna polymerase i transcription initiation
(R-HSA-73762)
Rna polymerase i transcription termination
(R-HSA-73863)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr2
(R-HSA-5654738)
Signaling by fgfr2 iiia tm
(R-HSA-8851708)
Signaling by fgfr2 in disease
(R-HSA-5655253)
Signaling by fgfr in disease
(R-HSA-1226099)
Signaling by nuclear receptors
(R-HSA-9006931)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Tat-mediated elongation of the hiv-1 transcript
(R-HSA-167246)
Tat-mediated hiv elongation arrest and recovery
(R-HSA-167243)
Telomere maintenance
(R-HSA-157579)
Tp53 regulates transcription of dna repair genes
(R-HSA-6796648)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-HSA-6781827)
Transcriptional regulation by small rnas
(R-HSA-5578749)
Transcriptional regulation by tp53
(R-HSA-3700989)
Transcription of the hiv genome
(R-HSA-167172)
Viral infection pathways
(R-HSA-9824446)
Viral messenger rna synthesis
(R-HSA-168325)
Dna binding
(GO:0003677)
Rna polymerase i activity
(GO:0001054)
Rna polymerase ii activity
(GO:0001055)
Rna polymerase iii activity
(GO:0001056)
Transcription by rna polymerase i
(GO:0006360)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 311.6135
Cell Significance Index: -48.4700
Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 212.4242
Cell Significance Index: -53.8800
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 135.3038
Cell Significance Index: -63.8800
Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 128.6008
Cell Significance Index: -52.2500
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 117.6161
Cell Significance Index: -60.5000
Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 54.8315
Cell Significance Index: -52.3500
Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 48.8095
Cell Significance Index: -60.1800
Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 16.2720
Cell Significance Index: -64.2100
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 15.7791
Cell Significance Index: -42.2700
Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.5334
Cell Significance Index: -47.7100
Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.6037
Cell Significance Index: -18.8300
Cell Name: kidney cell (CL1000497)
Fold Change: 2.2707
Cell Significance Index: 18.1300
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.1725
Cell Significance Index: 101.2900
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.0869
Cell Significance Index: 98.0800
Cell Name: granulosa cell (CL0000501)
Fold Change: 1.8296
Cell Significance Index: 48.1100
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.7120
Cell Significance Index: 35.8400
Cell Name: cell in vitro (CL0001034)
Fold Change: 1.5845
Cell Significance Index: 865.3200
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.5067
Cell Significance Index: 206.9100
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.2593
Cell Significance Index: 13.6900
Cell Name: odontoblast (CL0000060)
Fold Change: 1.2280
Cell Significance Index: 157.4200
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.2260
Cell Significance Index: 11.2900
Cell Name: lactocyte (CL0002325)
Fold Change: 1.1903
Cell Significance Index: 153.7800
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.0612
Cell Significance Index: 130.4900
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.0392
Cell Significance Index: 459.4500
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0075
Cell Significance Index: 181.6200
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.9945
Cell Significance Index: 74.1200
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8867
Cell Significance Index: 144.2100
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8446
Cell Significance Index: 22.9900
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.8443
Cell Significance Index: 59.7100
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7513
Cell Significance Index: 269.4800
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.7314
Cell Significance Index: 25.4200
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6361
Cell Significance Index: 75.0100
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6012
Cell Significance Index: 120.6000
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.5348
Cell Significance Index: 14.2800
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4740
Cell Significance Index: 10.2700
Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4452
Cell Significance Index: 28.7300
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4176
Cell Significance Index: 11.9700
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4123
Cell Significance Index: 21.4200
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3426
Cell Significance Index: 15.5300
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3295
Cell Significance Index: 17.3000
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3262
Cell Significance Index: 55.7000
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.3235
Cell Significance Index: 9.5000
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2900
Cell Significance Index: 55.1800
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2832
Cell Significance Index: 28.0100
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.2452
Cell Significance Index: 6.5600
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.1866
Cell Significance Index: 2.1200
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1774
Cell Significance Index: 35.2000
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1524
Cell Significance Index: 4.3900
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0812
Cell Significance Index: 61.4600
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0509
Cell Significance Index: 95.7700
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0269
Cell Significance Index: 0.4500
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0139
Cell Significance Index: 21.4700
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0020
Cell Significance Index: -1.4400
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0054
Cell Significance Index: -4.0300
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0102
Cell Significance Index: -18.8900
Cell Name: tuft cell of colon (CL0009041)
Fold Change: -0.0184
Cell Significance Index: -16.6100
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0418
Cell Significance Index: -26.1300
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0469
Cell Significance Index: -63.7800
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0491
Cell Significance Index: -31.1800
Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0505
Cell Significance Index: -5.1600
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0694
Cell Significance Index: -39.1200
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0927
Cell Significance Index: -42.1000
Cell Name: peg cell (CL4033014)
Fold Change: -0.1091
Cell Significance Index: -2.5200
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1258
Cell Significance Index: -6.3600
Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1417
Cell Significance Index: -3.6200
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1453
Cell Significance Index: -16.6500
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1457
Cell Significance Index: -8.9600
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1479
Cell Significance Index: -31.1600
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1730
Cell Significance Index: -49.7700
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1844
Cell Significance Index: -5.9000
Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2043
Cell Significance Index: -23.8100
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2626
Cell Significance Index: -7.3400
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.2894
Cell Significance Index: -10.1700
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3139
Cell Significance Index: -45.6300
Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3427
Cell Significance Index: -39.1200
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3832
Cell Significance Index: -25.7700
Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.4144
Cell Significance Index: -6.2100
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4267
Cell Significance Index: -32.7500
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.4411
Cell Significance Index: -7.8000
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4685
Cell Significance Index: -29.5300
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5243
Cell Significance Index: -54.5900
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5299
Cell Significance Index: -41.9700
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6303
Cell Significance Index: -35.3700
Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7135
Cell Significance Index: -29.2400
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.7207
Cell Significance Index: -31.8800
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.7361
Cell Significance Index: -13.6100
Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7800
Cell Significance Index: -40.6300
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.7859
Cell Significance Index: -10.0700
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.8831
Cell Significance Index: -26.0100
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.9119
Cell Significance Index: -34.5300
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.0302
Cell Significance Index: -63.1600
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -1.1089
Cell Significance Index: -15.1300
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.2256
Cell Significance Index: -44.9900
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.2601
Cell Significance Index: -32.3900
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.2715
Cell Significance Index: -7.8300
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.2807
Cell Significance Index: -13.2600
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.3439
Cell Significance Index: -36.0100
Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.4242
Cell Significance Index: -40.6400
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.4296
Cell Significance Index: -50.0800
Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.4696
Cell Significance Index: -32.1800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** 1. **Function**: The POLR2F gene is a subunit of the RNA polymerase II complex, which is responsible for transcribing protein-coding genes in eukaryotic cells. 2. **Expression**: The gene is significantly expressed in various cell types, including those mentioned above. 3. **Subcellular localization**: The POLR2F protein is localized to the nucleus. 4. **Post-translational modifications**: The POLR2F protein undergoes phosphorylation, which is essential for its function. **Pathways and Functions** The POLR2F gene is involved in various cellular pathways, including: 1. **Transcription**: The POLR2F gene is essential for transcribing protein-coding genes in eukaryotic cells. 2. **Transcriptional regulation**: The POLR2F gene is involved in regulating the expression of genes involved in various cellular processes. 3. **DNA repair**: The POLR2F gene plays a role in maintaining genome stability by regulating DNA repair processes. 4. **Cell cycle regulation**: The POLR2F gene is involved in regulating the cell cycle, particularly during the S phase. 5. **Immune system regulation**: The POLR2F gene is involved in regulating the immune system, particularly during the response to viral infections. **Clinical Significance** Dysregulation of the POLR2F gene has been implicated in several diseases, including: 1. **Cancer**: The POLR2F gene is often overexpressed in various types of cancer, including breast, lung, and colon cancer. 2. **Neurological disorders**: The POLR2F gene has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 3. **Infectious diseases**: The POLR2F gene is involved in regulating the expression of genes involved in viral infections, such as HIV-1. 4. **Developmental disorders**: The POLR2F gene is involved in regulating the expression of genes involved in embryonic development, particularly during the formation of the nervous system. In conclusion, the POLR2F gene is a crucial component of the RNA polymerase II complex, which plays a central role in transcribing protein-coding genes in eukaryotic cells. Its dysregulation has been implicated in several diseases, including cancer, neurological disorders, and infectious diseases. Further research is needed to fully understand the role of the POLR2F gene in these diseases and to develop therapeutic strategies to target this gene.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

DNA-directed RNA polymerases I, II, and III subunit RPABC2
B0QYL9_HUMAN

Genular Protein ID: 3401093711

Symbol: RPAB2_HUMAN

Name: DNA-directed RNA polymerases I, II, and III subunit RPABC2

UniProtKB Accession Codes:

P61218 P41584 Q6IAY3

Database IDs:

Citations:

PubMed ID: 7803819

Title: A 14.4 KDa acidic subunit of human RNA polymerase II with a putative leucine-zipper.

PubMed ID: 7803819

DOI: 10.3109/10425179409020860

PubMed ID: 8786150

Title: Genomic structure of the RNA polymerase II small subunit (hRPB14.4) locus (POLRF) and mapping to 22q13.1 by sequence identity.

PubMed ID: 8786150

DOI: 10.1006/geno.1996.0312

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9852112

Title: Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

PubMed ID: 9852112

DOI: 10.1074/jbc.273.51.34444

PubMed ID: 20413673

Title: Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells.

PubMed ID: 20413673

DOI: 10.1101/gr.101337.109

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10542096

Title: Solution structure of the hRPABC14.4 subunit of human RNA polymerases.

PubMed ID: 10542096

DOI: 10.1038/14923

PubMed ID: 27193682

Title: Near-atomic resolution visualization of human transcription promoter opening.

PubMed ID: 27193682

DOI: 10.1038/nature17970

PubMed ID: 30190596

Title: Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.

PubMed ID: 30190596

DOI: 10.1038/s41594-018-0118-5

PubMed ID: 33335104

Title: Structure of human RNA polymerase III.

PubMed ID: 33335104

DOI: 10.1038/s41467-020-20262-5

PubMed ID: 34671025

Title: Structure of the human RNA polymerase I elongation complex.

PubMed ID: 34671025

DOI: 10.1038/s41421-021-00335-5

PubMed ID: 33674783

Title: Structure of human RNA polymerase III elongation complex.

PubMed ID: 33674783

DOI: 10.1038/s41422-021-00472-2

PubMed ID: 34675218

Title: Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.

PubMed ID: 34675218

DOI: 10.1038/s41467-021-26402-9

PubMed ID: 33558764

Title: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.

PubMed ID: 33558764

DOI: 10.1038/s41594-020-00555-5

PubMed ID: 34887565

Title: Cryo-EM structures of human RNA polymerase I.

PubMed ID: 34887565

DOI: 10.1038/s41594-021-00693-4

PubMed ID: 33558766

Title: Structural insights into transcriptional regulation of human RNA polymerase III.

PubMed ID: 33558766

DOI: 10.1038/s41594-021-00557-x

PubMed ID: 36271492

Title: The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.

PubMed ID: 36271492

DOI: 10.26508/lsa.202201568

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 127
Mass: 14478
Checksum: 6362B0D7EB3F0921
Sequence:

MSDNEDNFDG DDFDDVEEDE GLDDLENAEE EGQENVEILP SGERPQANQK RITTPYMTKY 
ERARVLGTRA LQIAMCAPVM VELEGETDPL LIAMKELKAR KIPIIIRRYL PDGSYEDWGV 
DELIITD

Genular Protein ID: 1771510502

Symbol: B0QYL9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0QYL9

Database IDs:

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 158
Mass: 17574
Checksum: 066D69F202A354E3
Sequence:

MSDNEDNFDG DDFDDVEEDE GLDDLENAEE EGQENVEILP SGERPQANQK RITTPYMTKY 
ERARVLGTRA LQIAMCAPVM VELEGETDPL LIAMKELNAR SASEPPGEEP PWMDRGTRDE 
HLPSCPGCPA VASNTRCCPP AACLPGISLS RRRRLREE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: POLR2F

Associated with

Cells (max top 100)

Other Information

A 14.4 KDa acidic subunit of human RNA polymerase II with a putative leucine-zipper. PubMed ID: 7803819

Genomic structure of the RNA polymerase II small subunit (hRPB14.4) locus (POLRF) and mapping to 22q13.1 by sequence identity. PubMed ID: 8786150

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. PubMed ID: 9852112

Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells. PubMed ID: 20413673

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Solution structure of the hRPABC14.4 subunit of human RNA polymerases. PubMed ID: 10542096

Near-atomic resolution visualization of human transcription promoter opening. PubMed ID: 27193682

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. PubMed ID: 30190596

Structure of human RNA polymerase III. PubMed ID: 33335104

Structure of the human RNA polymerase I elongation complex. PubMed ID: 34671025

Structure of human RNA polymerase III elongation complex. PubMed ID: 33674783

Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. PubMed ID: 34675218

Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. PubMed ID: 33558764

Cryo-EM structures of human RNA polymerase I. PubMed ID: 34887565

Structural insights into transcriptional regulation of human RNA polymerase III. PubMed ID: 33558766

The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. PubMed ID: 36271492

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974

The DNA sequence of human chromosome 22. PubMed ID: 10591208

Initial sequencing and analysis of the human genome. PubMed ID: 11237011

Finishing the euchromatic sequence of the human genome. PubMed ID: 15496913

Finishing the finished human chromosome 22 sequence. PubMed ID: 18477386

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Database document:

PubMed ID: 7803819

PubMed ID: 8786150

PubMed ID: 15461802

PubMed ID: 10591208

PubMed ID: 15489334

PubMed ID: 9852112

PubMed ID: 20413673

PubMed ID: 20068231

PubMed ID: 24275569

PubMed ID: 10542096

PubMed ID: 27193682

PubMed ID: 30190596

PubMed ID: 33335104

PubMed ID: 34671025

PubMed ID: 33674783

PubMed ID: 34675218

PubMed ID: 33558764

PubMed ID: 34887565

PubMed ID: 33558766

PubMed ID: 36271492

PubMed ID: 16959974

PubMed ID: 10591208

PubMed ID: 11237011

PubMed ID: 15496913

PubMed ID: 18477386

PubMed ID: 20068231

PubMed ID: 24275569