POLR2I | ENSG00000105258 | NCBI 5438

Details for: POLR2I

Gene ID: 5438

Symbol: POLR2I

Ensembl ID: ENSG00000105258

Description: RNA polymerase II subunit I

Associated with

Abortive elongation of hiv-1 transcript in the absence of tat
(R-HSA-167242)
Activation of anterior hox genes in hindbrain development during early embryogenesis
(R-HSA-5617472)
Activation of hox genes during differentiation
(R-HSA-5619507)
Cell cycle
(R-HSA-1640170)
Chromosome maintenance
(R-HSA-73886)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Dna repair
(R-HSA-73894)
Dual incision in tc-ner
(R-HSA-6782135)
Esr-mediated signaling
(R-HSA-8939211)
Estrogen-dependent gene expression
(R-HSA-9018519)
Fgfr2 alternative splicing
(R-HSA-6803529)
Fgfr2 mutant receptor activation
(R-HSA-1839126)
Formation of hiv-1 elongation complex containing hiv-1 tat
(R-HSA-167200)
Formation of hiv elongation complex in the absence of hiv tat
(R-HSA-167152)
Formation of rna pol ii elongation complex
(R-HSA-112382)
Formation of tc-ner pre-incision complex
(R-HSA-6781823)
Formation of the early elongation complex
(R-HSA-113418)
Formation of the hiv-1 early elongation complex
(R-HSA-167158)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-HSA-6782210)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Gene silencing by rna
(R-HSA-211000)
Hiv elongation arrest and recovery
(R-HSA-167287)
Hiv infection
(R-HSA-162906)
Hiv life cycle
(R-HSA-162587)
Hiv transcription elongation
(R-HSA-167169)
Hiv transcription initiation
(R-HSA-167161)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
Inhibition of dna recombination at telomere
(R-HSA-9670095)
Late phase of hiv life cycle
(R-HSA-162599)
Metabolism of rna
(R-HSA-8953854)
Microrna (mirna) biogenesis
(R-HSA-203927)
Mrna capping
(R-HSA-72086)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Mrna splicing - minor pathway
(R-HSA-72165)
Nucleotide excision repair
(R-HSA-5696398)
Pausing and recovery of hiv elongation
(R-HSA-167290)
Pausing and recovery of tat-mediated hiv elongation
(R-HSA-167238)
Piwi-interacting rna (pirna) biogenesis
(R-HSA-5601884)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Rna pol ii ctd phosphorylation and interaction with ce
(R-HSA-77075)
Rna pol ii ctd phosphorylation and interaction with ce during hiv infection
(R-HSA-167160)
Rna polymerase ii hiv promoter escape
(R-HSA-167162)
Rna polymerase ii pre-transcription events
(R-HSA-674695)
Rna polymerase ii promoter escape
(R-HSA-73776)
Rna polymerase ii transcribes snrna genes
(R-HSA-6807505)
Rna polymerase ii transcription
(R-HSA-73857)
Rna polymerase ii transcription elongation
(R-HSA-75955)
Rna polymerase ii transcription initiation
(R-HSA-75953)
Rna polymerase ii transcription initiation and promoter clearance
(R-HSA-76042)
Rna polymerase ii transcription pre-initiation and promoter opening
(R-HSA-73779)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr2
(R-HSA-5654738)
Signaling by fgfr2 iiia tm
(R-HSA-8851708)
Signaling by fgfr2 in disease
(R-HSA-5655253)
Signaling by fgfr in disease
(R-HSA-1226099)
Signaling by nuclear receptors
(R-HSA-9006931)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Tat-mediated elongation of the hiv-1 transcript
(R-HSA-167246)
Tat-mediated hiv elongation arrest and recovery
(R-HSA-167243)
Telomere maintenance
(R-HSA-157579)
Tp53 regulates transcription of dna repair genes
(R-HSA-6796648)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-HSA-6781827)
Transcriptional regulation by small rnas
(R-HSA-5578749)
Transcriptional regulation by tp53
(R-HSA-3700989)
Transcription of the hiv genome
(R-HSA-167172)
Viral infection pathways
(R-HSA-9824446)
Viral messenger rna synthesis
(R-HSA-168325)
Dna-directed 5'-3' rna polymerase activity
(GO:0003899)
Maintenance of transcriptional fidelity during transcription elongation by rna polymerase ii
(GO:0001193)
Nucleic acid binding
(GO:0003676)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Rna polymerase ii, core complex
(GO:0005665)
Transcription-coupled nucleotide-excision repair
(GO:0006283)
Transcription by rna polymerase ii
(GO:0006366)
Transcription initiation at rna polymerase ii promoter
(GO:0006367)
Zinc ion binding
(GO:0008270)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 237.1015
Cell Significance Index: -36.8800
Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 202.1736
Cell Significance Index: -51.2800
Cell Name: embryonic stem cell (CL0002322)
Fold Change: 150.0676
Cell Significance Index: -61.8200
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 128.3777
Cell Significance Index: -60.6100
Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 123.9117
Cell Significance Index: -50.3400
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 110.1315
Cell Significance Index: -56.6500
Cell Name: ileal goblet cell (CL1000326)
Fold Change: 90.4143
Cell Significance Index: -60.6700
Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 52.9881
Cell Significance Index: -50.5900
Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 47.6294
Cell Significance Index: -58.7300
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.3063
Cell Significance Index: -49.0400
Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 16.1529
Cell Significance Index: -63.7400
Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.4859
Cell Significance Index: -38.3500
Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 3.8287
Cell Significance Index: 32.1600
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 2.8355
Cell Significance Index: 17.4500
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.7026
Cell Significance Index: 126.0100
Cell Name: peg cell (CL4033014)
Fold Change: 2.3893
Cell Significance Index: 55.2000
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.3758
Cell Significance Index: 386.4000
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.3215
Cell Significance Index: 121.8900
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.2413
Cell Significance Index: 307.7900
Cell Name: cell in vitro (CL0001034)
Fold Change: 2.1299
Cell Significance Index: 1163.1700
Cell Name: kidney cell (CL1000497)
Fold Change: 2.0879
Cell Significance Index: 16.6700
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.8068
Cell Significance Index: 49.1800
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.7998
Cell Significance Index: 84.5900
Cell Name: granulosa cell (CL0000501)
Fold Change: 1.7140
Cell Significance Index: 45.0700
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.5339
Cell Significance Index: 678.1800
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.4960
Cell Significance Index: 269.6800
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.4830
Cell Significance Index: 104.8900
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.4642
Cell Significance Index: 180.0400
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.4031
Cell Significance Index: 104.5700
Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.3581
Cell Significance Index: 20.3500
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.3378
Cell Significance Index: 60.6400
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 1.3239
Cell Significance Index: 15.0400
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.3097
Cell Significance Index: 27.4200
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.3020
Cell Significance Index: 11.9900
Cell Name: lactocyte (CL0002325)
Fold Change: 1.2587
Cell Significance Index: 162.6200
Cell Name: odontoblast (CL0000060)
Fold Change: 1.2540
Cell Significance Index: 160.7500
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.1712
Cell Significance Index: 31.3300
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.0259
Cell Significance Index: 120.9800
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.0017
Cell Significance Index: 10.8900
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.9294
Cell Significance Index: 58.5800
Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.7663
Cell Significance Index: 49.4400
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7028
Cell Significance Index: 36.5100
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5899
Cell Significance Index: 17.0000
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5076
Cell Significance Index: 96.5900
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4651
Cell Significance Index: 46.0100
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.4243
Cell Significance Index: 12.4600
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.3822
Cell Significance Index: 13.2800
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3313
Cell Significance Index: 299.1000
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1072
Cell Significance Index: 81.1700
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0721
Cell Significance Index: 52.8400
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0426
Cell Significance Index: 8.5400
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0359
Cell Significance Index: 0.6000
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0281
Cell Significance Index: 0.7500
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0064
Cell Significance Index: 2.2900
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0218
Cell Significance Index: -41.1000
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0316
Cell Significance Index: -5.3900
Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0391
Cell Significance Index: -0.6700
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0397
Cell Significance Index: -73.2200
Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0410
Cell Significance Index: -4.1900
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0453
Cell Significance Index: -69.6900
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0542
Cell Significance Index: -40.1600
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0547
Cell Significance Index: -74.3700
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0727
Cell Significance Index: -46.2000
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0891
Cell Significance Index: -50.2500
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.1078
Cell Significance Index: -1.3800
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1097
Cell Significance Index: -49.7800
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1145
Cell Significance Index: -71.4800
Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.1179
Cell Significance Index: -1.7900
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1475
Cell Significance Index: -29.2700
Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1616
Cell Significance Index: -8.4200
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1651
Cell Significance Index: -47.4900
Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1932
Cell Significance Index: -22.5200
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2191
Cell Significance Index: -13.4700
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2459
Cell Significance Index: -28.1700
Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2525
Cell Significance Index: -6.4500
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3162
Cell Significance Index: -66.6100
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.3231
Cell Significance Index: -7.0000
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3390
Cell Significance Index: -26.8500
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3600
Cell Significance Index: -10.3200
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3694
Cell Significance Index: -11.8300
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3732
Cell Significance Index: -54.2500
Cell Name: thyroid follicular cell (CL0002258)
Fold Change: -0.4424
Cell Significance Index: -4.7000
Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.4709
Cell Significance Index: -3.8400
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.5871
Cell Significance Index: -8.0100
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6125
Cell Significance Index: -63.7800
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.6788
Cell Significance Index: -18.9700
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.6983
Cell Significance Index: -12.3400
Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.7114
Cell Significance Index: -15.1500
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.8187
Cell Significance Index: -8.4800
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.8223
Cell Significance Index: -63.1000
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.8749
Cell Significance Index: -21.8700
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.8998
Cell Significance Index: -60.5000
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.9042
Cell Significance Index: -50.7400
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9698
Cell Significance Index: -59.4600
Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.9782
Cell Significance Index: -7.5400
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.0133
Cell Significance Index: -29.8500
Cell Name: mesodermal cell (CL0000222)
Fold Change: -1.0351
Cell Significance Index: -6.4800
Cell Name: melanocyte of skin (CL1000458)
Fold Change: -1.0538
Cell Significance Index: -14.7700
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.1146
Cell Significance Index: -20.6000
Cell Name: retinal rod cell (CL0000604)
Fold Change: -1.2264
Cell Significance Index: -14.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics:** POLR2I is a 73-kDa protein that is highly conserved across species. It is a subunit of the Pol II enzyme, which is responsible for transcribing approximately 80% of the human genome. POLR2I is responsible for the phosphorylation and interaction of the Pol II C-terminal domain (CTD) with other proteins, which is essential for transcription elongation and processivity. The protein also interacts with other transcription factors and co-factors to regulate gene expression. **Pathways and Functions:** POLR2I is involved in various cellular pathways, including: 1. **Transcription elongation:** POLR2I plays a crucial role in the phosphorylation and interaction of the Pol II CTD, which is essential for transcription elongation and processivity. 2. **Gene expression:** POLR2I regulates gene expression by interacting with transcription factors and co-factors, including the CTD, to control the recruitment of RNA polymerase II to promoters. 3. **DNA repair:** POLR2I is involved in the repair of DNA damage by interacting with other proteins to regulate the activity of DNA repair enzymes. 4. **Cell cycle regulation:** POLR2I is required for the regulation of the cell cycle by interacting with other proteins to control the expression of genes involved in cell proliferation and survival. 5. **Neurological disorders:** POLR2I has been implicated in the regulation of gene expression in the nervous system, and its dysregulation has been associated with neurological disorders, including Alzheimer's disease and schizophrenia. **Clinical Significance:** Dysregulation of POLR2I has been implicated in various diseases, including: 1. **Cancer:** POLR2I is often overexpressed in cancer cells, where it contributes to the regulation of gene expression and tumorigenesis. 2. **Neurological disorders:** POLR2I has been implicated in the regulation of gene expression in the nervous system, and its dysregulation has been associated with neurological disorders, including Alzheimer's disease and schizophrenia. 3. **Infectious diseases:** POLR2I has been implicated in the regulation of gene expression in response to viral infections, and its dysregulation has been associated with the progression of infectious diseases, including HIV-1 and influenza. 4. **Aging and longevity:** POLR2I has been implicated in the regulation of gene expression in response to cellular stress, and its dysregulation has been associated with aging and longevity. In conclusion, POLR2I is a critical regulator of transcription and beyond, with implications for various diseases, including cancer, neurological disorders, infectious diseases, and aging. Further research is needed to fully understand the mechanisms by which POLR2I regulates gene expression and its role in disease.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

DNA-directed RNA polymerase II subunit RPB9

Genular Protein ID: 2280916840

Symbol: RPB9_HUMAN

Name: DNA-directed RNA polymerase II subunit RPB9

UniProtKB Accession Codes:

P36954 B2R5J2 Q6NW05

Database IDs:

Citations:

PubMed ID: 8265347

Title: Structure of the gene encoding the 14.5 kDa subunit of human RNA polymerase II.

PubMed ID: 8265347

DOI: 10.1093/nar/21.23.5345

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9852112

Title: Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

PubMed ID: 9852112

DOI: 10.1074/jbc.273.51.34444

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 27193682

Title: Near-atomic resolution visualization of human transcription promoter opening.

PubMed ID: 27193682

DOI: 10.1038/nature17970

PubMed ID: 30190596

Title: Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.

PubMed ID: 30190596

DOI: 10.1038/s41594-018-0118-5

Sequence Information:

Length: 125
Mass: 14523
Checksum: 6520687BB57EE018
Sequence:

MEPDGTYEPG FVGIRFCQEC NNMLYPKEDK ENRILLYACR NCDYQQEADN SCIYVNKITH 
EVDELTQIIA DVSQDPTLPR TEDHPCQKCG HKEAVFFQSH SARAEDAMRL YYVCTAPHCG 
HRWTE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: POLR2I

Associated with

Cells (max top 100)

Other Information

Structure of the gene encoding the 14.5 kDa subunit of human RNA polymerase II. PubMed ID: 8265347

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. PubMed ID: 9852112

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Near-atomic resolution visualization of human transcription promoter opening. PubMed ID: 27193682

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. PubMed ID: 30190596