Details for: PSMA7
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 5.24
Marker Score: 3,951 - Cell Name: mature T cell (CL0002419)
Fold Change: 3.9
Marker Score: 38,598 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 3.64
Marker Score: 5,608 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 3.49
Marker Score: 4,209 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 3.38
Marker Score: 3,526 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 3.37
Marker Score: 188,527 - Cell Name: blood cell (CL0000081)
Fold Change: 3.31
Marker Score: 38,458 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 3.31
Marker Score: 1,058 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 3.12
Marker Score: 4,292 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.1
Marker Score: 105,487 - Cell Name: supporting cell (CL0000630)
Fold Change: 3.07
Marker Score: 5,772 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.05
Marker Score: 7,452 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 3
Marker Score: 23,461 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.98
Marker Score: 39,298 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.98
Marker Score: 1,340 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.96
Marker Score: 3,161 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.94
Marker Score: 3,363 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 2.94
Marker Score: 9,275 - Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 2.93
Marker Score: 3,252 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.93
Marker Score: 699 - Cell Name: malignant cell (CL0001064)
Fold Change: 2.92
Marker Score: 39,173 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 2.9
Marker Score: 2,903 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.9
Marker Score: 1,299 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.89
Marker Score: 100,102 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 2.86
Marker Score: 7,264 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.85
Marker Score: 3,071 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 2.85
Marker Score: 7,881 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 2.84
Marker Score: 1,668 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.84
Marker Score: 72,779 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.83
Marker Score: 2,223 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 2.83
Marker Score: 8,246 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 2.82
Marker Score: 3,991 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 2.81
Marker Score: 3,378 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.8
Marker Score: 2,385 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 2.79
Marker Score: 5,438 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 2.78
Marker Score: 4,027 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.77
Marker Score: 5,537 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 2.77
Marker Score: 1,851 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.75
Marker Score: 7,718 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.75
Marker Score: 3,576 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.74
Marker Score: 1,142 - Cell Name: epithelial cell (CL0000066)
Fold Change: 2.73
Marker Score: 4,350 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 2.71
Marker Score: 2,376 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.7
Marker Score: 23,262 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.7
Marker Score: 1,226 - Cell Name: myelocyte (CL0002193)
Fold Change: 2.69
Marker Score: 1,164 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 2.68
Marker Score: 14,067 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.67
Marker Score: 1,755 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.66
Marker Score: 29,961 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 2.66
Marker Score: 1,328 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.65
Marker Score: 16,969 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.65
Marker Score: 2,379 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.65
Marker Score: 17,247 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.65
Marker Score: 11,431 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.65
Marker Score: 2,972 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.65
Marker Score: 2,879 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 2.64
Marker Score: 139,703 - Cell Name: pro-T cell (CL0000827)
Fold Change: 2.64
Marker Score: 10,809 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.64
Marker Score: 26,752 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 2.64
Marker Score: 4,712 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 2.64
Marker Score: 17,186 - Cell Name: renal intercalated cell (CL0005010)
Fold Change: 2.63
Marker Score: 1,405 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.63
Marker Score: 2,217 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 2.63
Marker Score: 12,933 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 2.62
Marker Score: 693 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.61
Marker Score: 5,458 - Cell Name: naive T cell (CL0000898)
Fold Change: 2.61
Marker Score: 1,681 - Cell Name: Unknown (CL0000548)
Fold Change: 2.61
Marker Score: 1,899 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 2.6
Marker Score: 684 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.59
Marker Score: 832 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 2.59
Marker Score: 1,880 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 2.59
Marker Score: 6,250 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.59
Marker Score: 5,898 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.58
Marker Score: 6,752 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.58
Marker Score: 4,702 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 2.55
Marker Score: 10,954 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 2.55
Marker Score: 4,447 - Cell Name: basal cell (CL0000646)
Fold Change: 2.55
Marker Score: 3,290 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.54
Marker Score: 1,598 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 2.54
Marker Score: 2,160 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.54
Marker Score: 1,449 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 2.54
Marker Score: 1,311 - Cell Name: memory B cell (CL0000787)
Fold Change: 2.54
Marker Score: 1,921 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.54
Marker Score: 4,158 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 2.53
Marker Score: 1,301 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.53
Marker Score: 2,965 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 2.53
Marker Score: 2,444 - Cell Name: motor neuron (CL0000100)
Fold Change: 2.53
Marker Score: 1,500 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.53
Marker Score: 4,189 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 2.52
Marker Score: 1,031 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 2.52
Marker Score: 1,698 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 2.52
Marker Score: 18,785 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 2.52
Marker Score: 1,982 - Cell Name: enterocyte (CL0000584)
Fold Change: 2.51
Marker Score: 12,068 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.51
Marker Score: 4,272 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 2.5
Marker Score: 1,289 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 2.5
Marker Score: 1,041 - Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 2.49
Marker Score: 1,562 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.49
Marker Score: 4,000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.49
Marker Score: 9,593
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 871818572
Symbol: PSA7_HUMAN
Name: Proteasome subunit alpha type-7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8764072
Title: Proteasome complex as a potential cellular target of hepatitis B virus X protein.
PubMed ID: 8764072
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8610016
Title: A role for the proteasome regulator PA28alpha in antigen presentation.
PubMed ID: 8610016
DOI: 10.1038/381166a0
PubMed ID: 10748218
Title: Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex.
PubMed ID: 10748218
PubMed ID: 11389899
Title: Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7.
PubMed ID: 11389899
PubMed ID: 11713272
Title: Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation.
PubMed ID: 11713272
PubMed ID: 11574696
Title: C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification.
PubMed ID: 11574696
PubMed ID: 12119296
Title: Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells.
PubMed ID: 12119296
PubMed ID: 12181345
Title: Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.
PubMed ID: 12181345
PubMed ID: 14550573
Title: Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits.
PubMed ID: 14550573
PubMed ID: 15244466
Title: 20S proteasome prevents aggregation of heat-denatured proteins without PA700 regulatory subcomplex like a molecular chaperone.
PubMed ID: 15244466
DOI: 10.1021/bm049957a
PubMed ID: 14759258
PubMed ID: 14998988
Title: The proteasome alpha-subunit XAPC7 interacts specifically with Rab7 and late endosomes.
PubMed ID: 14998988
PubMed ID: 15987638
Title: Parkin interacts with the proteasome subunit alpha4.
PubMed ID: 15987638
PubMed ID: 16251969
Title: A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.
PubMed ID: 16251969
DOI: 10.1038/nature04106
PubMed ID: 16678104
Title: Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation.
PubMed ID: 16678104
PubMed ID: 17323924
Title: Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
PubMed ID: 17323924
DOI: 10.1021/bi061994u
PubMed ID: 18202793
Title: The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer.
PubMed ID: 18202793
PubMed ID: 19362550
Title: Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome.
PubMed ID: 19362550
PubMed ID: 19734229
Title: Negative regulation of MAVS-mediated innate immune response by PSMA7.
PubMed ID: 19734229
PubMed ID: 19442227
Title: PSMA7, a potential biomarker of diseases.
PubMed ID: 19442227
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27176742
Title: Human 20S proteasome activity towards fluorogenic peptides of various chain lengths.
PubMed ID: 27176742
PubMed ID: 26133119
Title: Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core.
PubMed ID: 26133119
DOI: 10.1038/ncomms8573
PubMed ID: 25599644
Title: Crystal structure of the human 20S proteasome in complex with carfilzomib.
PubMed ID: 25599644
PubMed ID: 27428775
PubMed ID: 27342858
Title: Structure of the human 26S proteasome at a resolution of 3.9 Aa.
PubMed ID: 27342858
PubMed ID: 27493187
Title: The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
PubMed ID: 27493187
PubMed ID: 34711951
Title: AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
PubMed ID: 34711951
PubMed ID: 23033978
Title: Diagnostic exome sequencing in persons with severe intellectual disability.
PubMed ID: 23033978
Sequence Information:
- Length: 248
- Mass: 27887
- Checksum: 5DD0276A1C2DEF91
- Sequence:
MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGRDI VVLGVEKKSV AKLQDERTVR KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDEA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQSLKIL NPEEIEKYVA EIEKEKEENE KKKQKKAS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.