Details for: RANBP1

Gene ID: 5902

Symbol: RANBP1

Ensembl ID: ENSG00000099901

Description: RAN binding protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 201.5812
    Cell Significance Index: -31.3600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 174.7335
    Cell Significance Index: -44.3200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 160.3845
    Cell Significance Index: -66.0700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 138.0362
    Cell Significance Index: -65.1700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 136.0715
    Cell Significance Index: -55.2800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 123.4775
    Cell Significance Index: -63.5200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 97.5080
    Cell Significance Index: -65.4300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 58.8745
    Cell Significance Index: -56.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 47.8322
    Cell Significance Index: -58.9800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.5381
    Cell Significance Index: -65.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.4659
    Cell Significance Index: -41.3600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.8819
    Cell Significance Index: -31.8300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 6.3037
    Cell Significance Index: 68.5300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 5.3229
    Cell Significance Index: 184.9700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 5.0437
    Cell Significance Index: 40.2700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.1898
    Cell Significance Index: 87.7000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 4.1647
    Cell Significance Index: 109.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 3.5238
    Cell Significance Index: 211.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.1619
    Cell Significance Index: 254.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.0951
    Cell Significance Index: 98.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.0637
    Cell Significance Index: 283.4000
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 1.9097
    Cell Significance Index: 16.4100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.9064
    Cell Significance Index: 1041.1500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.9044
    Cell Significance Index: 99.9900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.7918
    Cell Significance Index: 48.7700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.7022
    Cell Significance Index: 109.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6390
    Cell Significance Index: 201.5300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5694
    Cell Significance Index: 693.8900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.5693
    Cell Significance Index: 110.9900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.5378
    Cell Significance Index: 17.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.3482
    Cell Significance Index: 100.4800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3429
    Cell Significance Index: 242.0900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.2632
    Cell Significance Index: 163.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.2037
    Cell Significance Index: 35.3500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.1494
    Cell Significance Index: 14.7200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.1356
    Cell Significance Index: 145.5800
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.9913
    Cell Significance Index: 7.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.9798
    Cell Significance Index: 51.0400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.9665
    Cell Significance Index: 27.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9581
    Cell Significance Index: 44.6700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8150
    Cell Significance Index: 11.1200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.7821
    Cell Significance Index: 13.8200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7146
    Cell Significance Index: 19.0800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6971
    Cell Significance Index: 36.2100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6618
    Cell Significance Index: 15.2900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5821
    Cell Significance Index: 16.7700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5650
    Cell Significance Index: 55.8900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5538
    Cell Significance Index: 109.9100
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: 0.4310
    Cell Significance Index: 2.4500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.4196
    Cell Significance Index: 13.4400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3660
    Cell Significance Index: 3.3700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3255
    Cell Significance Index: 65.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3095
    Cell Significance Index: 58.8900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1486
    Cell Significance Index: 112.5000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1138
    Cell Significance Index: 1.9100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1064
    Cell Significance Index: 96.1100
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.0829
    Cell Significance Index: 0.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0821
    Cell Significance Index: 13.3500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0772
    Cell Significance Index: 3.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0755
    Cell Significance Index: 2.1100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0622
    Cell Significance Index: 3.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0592
    Cell Significance Index: 21.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0571
    Cell Significance Index: 3.9500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0125
    Cell Significance Index: 9.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0135
    Cell Significance Index: -25.3700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0357
    Cell Significance Index: -65.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0401
    Cell Significance Index: -61.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0408
    Cell Significance Index: -4.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0565
    Cell Significance Index: -76.7600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0583
    Cell Significance Index: -40.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0713
    Cell Significance Index: -52.8300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0755
    Cell Significance Index: -47.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0982
    Cell Significance Index: -55.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1085
    Cell Significance Index: -18.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1141
    Cell Significance Index: -51.7700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1238
    Cell Significance Index: -77.3000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1378
    Cell Significance Index: -3.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1561
    Cell Significance Index: -44.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2249
    Cell Significance Index: -4.7900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.2714
    Cell Significance Index: -1.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2885
    Cell Significance Index: -33.6200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3488
    Cell Significance Index: -21.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3522
    Cell Significance Index: -51.1900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3595
    Cell Significance Index: -75.7200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3802
    Cell Significance Index: -43.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4182
    Cell Significance Index: -9.0600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4714
    Cell Significance Index: -12.6100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5349
    Cell Significance Index: -42.3700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5847
    Cell Significance Index: -6.9700
  • Cell Name: theca cell (CL0000503)
    Fold Change: -0.6043
    Cell Significance Index: -3.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6136
    Cell Significance Index: -34.4300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6172
    Cell Significance Index: -64.2700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6678
    Cell Significance Index: -19.6700
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.6768
    Cell Significance Index: -4.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8454
    Cell Significance Index: -64.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.8794
    Cell Significance Index: -59.1300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.9284
    Cell Significance Index: -15.9100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0535
    Cell Significance Index: -64.5900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.0758
    Cell Significance Index: -28.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2093
    Cell Significance Index: -30.2300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RANBP1 is a small protein that belongs to the Ran-binding protein family. It is approximately 100 amino acids in length and contains a Ran-binding domain, which allows it to interact with the small GTPase Ran. RANBP1 is highly expressed in various cell types, including those of hematopoietic origin, such as erythroid progenitor cells and myeloid dendritic cells. Its expression is also observed in epithelial cells of the nephron and neural crest cells. RANBP1 has been shown to regulate various cellular processes, including nuclear envelope structure, nucleocytoplasmic transport, and cell cycle regulation. **Pathways and Functions** RANBP1 plays a critical role in several cellular pathways, including: 1. **Nucleocytoplasmic transport**: RANBP1 regulates the transport of proteins and RNAs between the nucleus and cytoplasm by binding to Ran and influencing its GTPase activity. 2. **Cell cycle regulation**: RANBP1 has been shown to regulate cell cycle progression by modulating the activity of cyclin-dependent kinases. 3. **Nuclear envelope structure**: RANBP1 plays a role in maintaining the structure and integrity of the nuclear envelope by regulating the activity of nuclear envelope proteins. 4. **GTPase regulation**: RANBP1 binds to Ran and regulates its GTPase activity, which is essential for various cellular processes, including nucleocytoplasmic transport and cell cycle regulation. **Clinical Significance** Dysregulation of RANBP1 has been implicated in several diseases, including: 1. **Cancer**: RANBP1 has been shown to be overexpressed in various types of cancer, including breast cancer, lung cancer, and colon cancer. Its overexpression has been associated with poor prognosis and reduced survival rates. 2. **Infectious diseases**: RANBP1 has been implicated in the regulation of HIV-1 replication and nuclear export. Its dysregulation has been associated with increased viral replication and reduced antiretroviral therapy efficacy. 3. **Neurological disorders**: RANBP1 has been shown to play a role in the regulation of neuronal function and synaptic plasticity. Its dysregulation has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, RANBP1 is a critical regulator of various cellular processes, including nucleocytoplasmic transport, cell cycle regulation, and nuclear envelope structure. Its dysregulation has been implicated in several diseases, including cancer, infectious diseases, and neurological disorders. Further research is needed to fully understand the role of RANBP1 in human disease and to develop therapeutic strategies to target its dysregulation.

Genular Protein ID: 1282909999

Symbol: RANG_HUMAN

Name: Ran-specific GTPase-activating protein

UniProtKB Accession Codes:

P43487 Q53EY3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 5 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OGP 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7882974

Title: Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1.

PubMed ID: 7882974

DOI: 10.1002/j.1460-2075.1995.tb07049.x

PubMed ID: 7616957

Title: RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4.

PubMed ID: 7616957

DOI: 10.1007/bf00290397

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 7891706

Title: Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.

PubMed ID: 7891706

DOI: 10.1128/mcb.15.4.2117

PubMed ID: 8896452

Title: Identification of different roles for RanGDP and RanGTP in nuclear protein import.

PubMed ID: 8896452

DOI: 10.1002/j.1460-2075.1996.tb00943.x

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 16428860

Title: Phosphorylation of RanGAP1 stabilizes its interaction with Ran and RanBP1.

PubMed ID: 16428860

DOI: 10.1247/csf.30.69

PubMed ID: 17671426

Title: Coordination of chromosome alignment and mitotic progression by the chromosome-based Ran signal.

PubMed ID: 17671426

DOI: 10.4161/cc.6.15.4487

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20485264

Title: An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1.

PubMed ID: 20485264

DOI: 10.1038/emboj.2010.89

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 11832950

Title: RanGAP mediates GTP hydrolysis without an arginine finger.

PubMed ID: 11832950

DOI: 10.1038/415662a

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 201
  • Mass: 23310
  • Checksum: 05FC9B35DADA48C9
  • Sequence:
    • MAAAKDTHED HDTSTENTDE SNHDPQFEPI VSLPEQEIKT LEEDEEELFK MRAKLFRFAS 
ENDLPEWKER GTGDVKLLKH KEKGAIRLLM RRDKTLKICA NHYITPMMEL KPNAGSDRAW 
VWNTHADFAD ECPKPELLAI RFLNAENAQK FKTKFEECRK EIEEREKKAG SGKNDHAEKV 
AEKLEALSVK EETKEDAEEK Q

Genular Protein ID: 2941686971

Symbol: B4DE76_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DE76

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 IntAct 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 204
  • Mass: 22948
  • Checksum: D6A5374EAC572125
  • Sequence:
    • MAAAKDTHED HDTSTENTDE SNHDPQFEPI VSLPEQEIKT LEEDEEELFK MRAKLFRFAS 
ENDLPEWKER GTGDVKLLKH KEKGAIRLLM RRDKTLKICA NHYITPMMEL KPNAGSDRAW 
VWNTHADFAD ECPKPELLAI RFLNAESEPR ALGTCLTWGS PAWQRGGLCA TNAVAFWGEG 
AVTGKCVVWA ALPCCLGAMP RLKP

Genular Protein ID: 503362846

Symbol: B3KUP2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KUP2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 6 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 ProteomicsDB 1 RefSeq 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 181
  • Mass: 20136
  • Checksum: 8F8B96E6DCFA0338
  • Sequence:
    • MGGRSAQAGL GTRITPMMEL KPNAGSDRAW VWNTHADFAD ECPKPELLAI RFLNAENAQK 
FKTKFEECRK EIEEREKKGD VVPWVGGLLC RLTLHLTILP GGCFFCLPDK HSRVLWPPHV 
SRVMQLPGDT GASWGALSTC QCCWPQSNWA GIGVRALPGA HQKVLYDGPR FVSQRAWSPL 
P

Genular Protein ID: 2203462081

Symbol: F6WQW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6WQW2

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 4 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 278
  • Mass: 31904
  • Checksum: 18FE9336089B0CD3
  • Sequence:
    • MGSALGRARR TLSGRPFQRA PCKTRRALSL SAALRNVTKA QGGCPKSLVL WGCRPKRPRK 
RRTSLKLAWR GTFCSSSLKI SEDTHEDHDT STENTDESNH DPQFEPIVSL PEQEIKTLEE 
DEEELFKMRA KLFRFASEND LPEWKERGTG DVKLLKHKEK GAIRLLMRRD KTLKICANHY 
ITPMMELKPN AGSDRAWVWN THADFADECP KPELLAIRFL NAENAQKFKT KFEECRKEIE 
EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.